Clinical trials: Influenza A
Childhood Influenza Vaccination, School-located Influenza Vaccination
Evaluation of the School Kids Influenza Prevention Project
Children whose parents receive text reminders are more likely to be consented to participate in the school located influenza vaccination clinic than children whose parents do not receive text reminders.
- Trial name
- SKIPP (NCT03307642)
- Testing
- Text message notification
- Where
- United States
- Volunteers
- 18,540 people
- Sponsor
- University of Rochester
PTEN Hamartoma Tumor Syndrome
Response of Immune System to Flu Vaccination in PHTS
this study evaluates the cellular and humoral immune response to seasonal influenze vaccination in PTEN Hamartoma Tumor Syndrome. All subjects will be administered flu vaccination, half of the subjects will be control subjects.
- Trial name
- RIPS (NCT03630523)
- Testing
- Influvac Tetra
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Healthy Adults
Safety Study of Seasonal Influenza Vaccine by Jet Injection
This research study involves testing of a device that can give injections (shots) without the use of a needle.
- Trial name
- NCT00987350
- Testing
- LectraJet, TIV by jet injection, Seasonal Trivalent Influenza Vaccine
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Influenza Viral Infections
Intradermal Influenza Vaccine in the Young
Influenza poses a heavy burden to our health service. The WHO estimates that seasonal influenza causes 250,000-500,000 deaths worldwide each year.
- Trial name
- NCT02103023
- Testing
- Imiquimod ointment, Aqueous cream, Intradermal influenza vaccine
- Where
- China
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Influenza
Safety and Efficacy of H1N1 Vaccines in Children Aged 6 Months to Less Than 10 Years of Age
The purpose of this study is to characterize the safety and efficacy of GSK Biologicals' H1N1 flu candidate vaccines GSK2340274A and GSK2340273A in children 6 months to less than 10 years of age.
- Trial name
- NCT01051661
- Testing
- GSK Biologicals' investigational vaccine GSK2340274A (alternative formulations), GSK Biologicals' investigational vaccine GSK2340273A (alternative formulations)
- Where
- 17 sites in Australia, Brazil and 6 more
- Volunteers
- 6,154 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Influenza
Study of the Ability of a Flu Vaccine to Prevent Flu Infection
The purpose of this study is to evaluate how effective the vaccine is at preventing subjects developing flu symptoms after they are directly exposed to flu virus.
- Trial name
- NCT00349037
- Testing
- Trivalent DNA vaccine with and without pPJV2012 administered by PMED
- Where
- United Kingdom
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- PowderMed
Influenza, Human, COVID-19
A Study to Evaluate the Safety, Tolerability, and Immunogenicity of Combined Modified RNA Vaccine Candidates Against COVID-19 and Influenza
Substudy A: This is a Phase 1 randomized, open-label study to describe the safety and immunogenicity of up to 3 dose- level combinations of modRNA quadrivalent influenza vaccine (qIRV (22/23)) and bivalent BNT162b2 (original/Omi…
- Trial name
- NCT05596734
- Testing
- bivalent BNT162b2 (original/Omi BA.4/BA.5), qIRV (22/23), QIV
- Where
- 59 sites in United States
- Volunteers
- 1,019 people, healthy volunteers welcome
- Sponsor
- BioNTech SE
Influenza Virus
A Study to Investigate VX-787 Given to Adult Volunteers Inoculated With Live Influenza Virus
The purpose of this study is to determine the antiviral activity and safety of VX-787 given to healthy adult volunteers that have been inoculated with the influenza virus.
- Trial name
- NCT01561807
- Testing
- VX-787
- Where
- United Kingdom
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Vertex Pharmaceuticals Incorporated
Influenza
Adjunctive Sirolimus and Oseltamivir Versus Oseltamivir Alone for Treatment of Influenza
Seasonal influenza epidemics are important causes of mortality and morbidity. Cytokine dysregulation, with high levels of pro-inflammatory cytokines, occurs in patients with severe influenza A(H1N1)pdm09 virus infection, A(H5N1)…
- Trial name
- NCT03901001
- Testing
- sirolimus and oseltamivir, Oseltamivir
- Where
- Hong Kong
- Volunteers
- 160 people
- Sponsor
- Chinese University of Hong Kong
Influenza, Human
Immunogenicity and Safety of Quadrivalent Influenza Vaccine in Children Aged 6~35 Months
This study is a multi-center, randomized, double-blind Phase III Clinical trial. The purpose of this study is to assess the immunogenicity and safety of the quadrivalent cell culture-derived influenza vaccine compare to the…
- Trial name
- NCT03020628
- Testing
- NBP607-QIV, NBP607-TIV
- Where
- 12 sites in South Korea
- Volunteers
- 171 people, healthy volunteers welcome
- Sponsor
- SK Chemicals Co., Ltd.
Virus Diseases, RNA Virus Infections
Immunogenicity, Safety, Tolerability of a Plant-Made H5 VLP Influenza Vaccine
The primary objective is to assess the immunogenicity and safety and tolerability of two consecutive doses of H5 VLP Influenza vaccine given 21 days apart, at three dose levels: in part A: 20 µg, 30 µg and 45 µg combined with…
- Conditions
- Virus Diseases, RNA Virus Infections, Respiratory Tract Diseases, Respiratory Tract Infections
- Trial name
- NCT01244867
- Testing
- 20 micrograms dose H5 VLP, 30 micrograms dose H5 VLP, 45 micrograms dose H5 VLP
- Where
- Canada
- Volunteers
- 255 people, healthy volunteers welcome
- Sponsor
- Medicago
Influenza
A Study to Evaluate the Safety, Reactogenicity, and Immunogenicity of mRNA-1010 in Healthy Adults
The main purpose of the study is to evaluate the safety, reactogenicity, and the humoral immunogenicity of mRNA-1010 and comparator influenza vaccines against homologous influenza A and B strains at Day 29.
- Trial name
- NCT05606965
- Testing
- mRNA-1010, Egg-based Quadrivalent Influenza Vaccine, Adjuvanted Quadrivalent Influenza Vaccine
- Where
- United States
- Volunteers
- 172 people, healthy volunteers welcome
- Sponsor
- ModernaTX, Inc.
Influenza Vaccine
Preliminary Safety Assessment of a Quadrivalent Subunit Influenza Vaccine in China
This study evaluates the safety of the quadrivalent subunit influenza vaccine in individuals aged 3 years and older in Jiangsu Province, China.
- Trial name
- NCT07710586
- Testing
- quadrivalent subunit influenza vaccine
- Where
- 2 sites in China
- Volunteers
- 3,105 people, healthy volunteers welcome
- Sponsor
- Ab&B Bio-tech Co., Ltd.JS
Influenza, Human
Phase 3 Pivotal Trial of NanoFlu™ in Older Adults
A Phase 3, randomized, observer-blinded, active-controlled trial to evaluate the immunogenicity and safety of a recombinant quadrivalent nanoparticle influenza vaccine with Matrix-M1 adjuvant (NanoFlu) compared with a licensed…
- Trial name
- NCT04120194
- Testing
- NanoFlu, Fluzone Quadrivalent
- Where
- 19 sites in United States
- Volunteers
- 2,654 people, healthy volunteers welcome
- Sponsor
- Novavax
Human Influenza
Post-marketing Clinical Observation of an Inactivated Influenza Split Vaccine
Phase III clinical trial was carried out in Jintan city, Jiangsu Province, China in May, 2006. Trial results showed that the vaccine had proved safety and immunogenicity.
- Trial name
- NCT01568788
- Testing
- Inactivated Influenza Vaccine, Inactivated Influenza Vaccine of Pasteur, Inactivated Influenza Vaccine of GSK
- Where
- China
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Hualan Biological Engineering, Inc.
Influenza
Phase II Study of Pandemic Influenza Vaccine
The World Health Organisation has warned that an influenza pandemic is inevitable. The avian influenza H5N1 virus strain is the leading candidate to cause the next influenza pandemic.
- Trial name
- NCT00320346
- Testing
- Pandemic Influenza Vaccine
- Where
- 3 sites in Australia
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Seqirus
Influenza
ED Influenza Therapeutic Pilot Study: Oseltamivir vs. Peramivir
This pilot study is designed to demonstrate the feasibility of utilizing Emergency Departments (EDs) as a primary site for subject enrollment in clinical trials evaluating influenza therapeutics, and to provide pilot data for…
- Trial name
- NCT02609399
- Testing
- Oseltamivir, Peramivir
- Where
- 2 sites in United States
- Volunteers
- 180 people
- Sponsor
- Johns Hopkins University
Influenza
A Study to Evaluate the Safety and Efficacy of MK-1406/CD388 for Prevention of Influenza (MK-1406-005/CD388.SQ.3.06)
Approximately one billion cases of seasonal influenza occur annually. Of these, 3 to 5 million illnesses are severe and responsible for up to 650,000 deaths per year (WHO 2025).
- Trial name
- ANCHOR (NCT07159763)
- Testing
- MK-1406
- Where
- 185 sites in United States, Argentina and 4 more
- Volunteers
- 10,000 people
- Sponsor
- Cidara Therapeutics Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
Influenza, Fever
Safety of Two Trivalent Influenza Vaccines Evaluated in Children and Adolescents 4 to 17 Years of Age
Evaluate safety and tolerability of TIVa or TIVb vaccine in healthy children and adolescents 4 to 17 years of age.
- Trial name
- NCT01857206
- Testing
- Mammalian cell based flu vaccine, Egg based flu vaccine
- Where
- 34 sites in United States, Australia and 3 more
- Volunteers
- 2,055 people, healthy volunteers welcome
- Sponsor
- Novartis Vaccines
Virus Diseases
Safety, Tolerability and Clinical Effect of Danirixin in Adults With Influenza
Study 201682 is a Phase IIa, randomized, double blind, placebo-controlled four arm outpatient study evaluating the safety, tolerability and clinical effect of danirixin or danirixin + oseltamivir combination in comparison to…
- Trial name
- NCT02469298
- Testing
- GSK1325756 (Danirixin), Oseltamivir Phosphate
- Where
- 33 sites in United States, Australia and 1 more
- Volunteers
- 45 people
- Sponsor
- GlaxoSmithKline
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.