Clinical trials: Inflammatory Markers
Chronic Spinal Pain
RTMS and Steroid Joint Steroid Injection in Chronic Spinal Pain
Chronic spinal pain (CSP) is one of the most common chronic pain conditions globally. Steroid joint injections (SJI) are a routine treatment option for patients with CLBP that is recalcitrant to other treatments.
- Trial name
- NCT05840354
- Testing
- Magstim Rapid2
- Where
- 2 sites in Canada
- Volunteers
- 40 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Acute Coronary Syndrome
A Study to Evaluate the Safety of 12 Weeks of Dosing With GW856553 and Its Effects on Inflammatory Markers, Infarct Size, and Cardiac Function in Subjects With Myocardial Infarction Without ST-segment Elevation
This is a randomized, double-blind, placebo-controlled, parallel group, multi-center study to evaluate initial safety and efficacy of GW856553 in subjects with NSTEMI.
- Trial name
- Solstice (NCT00910962)
- Testing
- GW856553
- Where
- 108 sites in United States, Australia and 7 more
- Volunteers
- 526 people
- Sponsor
- GlaxoSmithKline
Inflammation, Chronic Kidney Disease
Role of Prohepcidin in Uremic Patients
The investigators aimed to study the effect of prohepcidin levels on hematologic parameters and inflammatory markers in non-diabetic uremic patients.
- Trial name
- NCT01735773
- Where
- Turkey (Türkiye)
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Haseki Training and Research Hospital
Diabetes Mellitus, Type 2
Effects of Legume Consumption on Adiponectin and Inflammatory Markers Among Adults
The aim of this randomized cross-over study was to determine the effects of legume consumption on adiponectin and inflammatory factors among first degree relatives of diabetic patients
- Trial name
- NCT01906086
- Testing
- nutritional intervention, life style intervention
- Where
- Iran
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Isfahan University of Medical Sciences
HELLP Syndrome
Study of Prognostic Values of Platelet Indices and Inflammatory Markers in Patients With HELLP Syndrome.
This study aims to evaluate the prognostic values of platelet indices and inflammatory markers in patients with HELLP syndrome as:- :-Primary outcome To investigate prognostic values of platelet indices and. .
- Trial name
- NCT07377786
- Testing
- Group I: 30 patients with HELLP syndrome
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sohag University
Cystic Fibrosis
Omega 3 Supplementation in Cystic Fibrosis Patients
Essential fatty acids (EFA) deficiency has been often reported in patients with cystic fibrosis (CF), particularly in those homozygous for the DF508 mutation.
- Trial name
- NCT00959010
- Testing
- omega-3 triglycerides
- Where
- Belgium
- Volunteers
- 15 people
- Sponsor
- Queen Fabiola Children's University Hospital
Trauma Injury, Trauma, Multiple
The Usefulness of Inflammatory Markers to Predict Poor Outcomes for Trauma Patients
1) Research Hypothesis 1. Trauma -> Inflammation -> Severe inflammation -> Poor prognosis 2. If the degree of inflammation in the serum is precisely measurable, the prognosis of patients with trauma can be predicted.
- Trial name
- NCT05441787
- Where
- South Korea
- Volunteers
- 89 people
- Sponsor
- Wonju Severance Christian Hospital
Periodontal Diseases, Smoking Cessation
Effect of Smoking Cessation on Salivary IL-1β and PGE-2 Levels Following Non-Surgical Periodontal Therapy
The aim of this study is to evaluate the effect of smoking cessation on inflammatory markers following non-surgical treatment of periodontal disease.
- Trial name
- NCT06145685
- Testing
- Minimally invasive non-surgical periodontal therapy, Conventional non-surgical periodontal therapy
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- October 6 University
Benign Paroxysmal Positional Vertigo (Disorder)
Comparing Oral Lumbrokinase DLBS1033 and Betahistine Mesylate in Benign Paroxysmal Positional Vertigo
The goal of this clinical trial is to learn if oral lumbrokinase DLBS1033 works better than betahistine mesylate on inflammation, quality of life, and dizziness symptoms of adult benign paroxysmal positional vertigo (BPPV)…
- Trial name
- NCT07075289
- Testing
- DLBS1033, Betahistine Mesylate tablet
- Where
- Indonesia
- Volunteers
- 44 people
- Sponsor
- Universitas Sebelas Maret
Depression
Inflammatory Biomarkers and Brain Metabolites, a Study Based on Magnetic Resonance Spectroscopy
Suicidal behaviors (SB) are a major health problem in France : 10 000 suicides and 220 000 suicide attempts every year. SB management is therefore a major public health issue.
- Trial name
- BICS (NCT03052855)
- Testing
- Magnetic Resonance Imaging (MRI) and biological samples
- Where
- France
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Asthmatic Smokers, Non-asthmatic Smokers
The Effects of Montelukast on Smokers With Asthma
The purpose of this study is: 1. To compare neutrophilia, eosinophilic inflammatory markers and asthma symptom indices between smokers and non-smokers. 2.
- Trial name
- NCT00712335
- Testing
- Fluticasone Propionate, Montelukast, Salmeterol
- Where
- South Korea
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Inje University
Asthma
To Evaluate the Inflammatory Markers in Adult Patients With Asthma Associated With Allergic Rhinitis Receiving Montelukast Therapy (0476-366)
To evaluate the changes in proinflammatory markers (ltd4 in urine) and eosinophil from peripheral blood after newly initiated montelukast therapy.
- Trial name
- NCT00398151
- Testing
- MK0476, montelukast sodium / Duration of Treatment: 12 Weeks
- Volunteers
- 58 people
- Sponsor
- Organon and Co
Retroperitoneal Sarcoma, Body Composition
Influence of Nutritional Status on Oncologic and Operative Outcome in Patients Operated for Retroperitoneal Sarcoma
This is a retrospective, observational study in consecutive patients operated on for primary RPS in the Institute of Oncology Ljubljana (Slovenia) between September 1999 and June 2020.
- Conditions
- Retroperitoneal Sarcoma, Body Composition, Malnutrition, Sarcopenia
- Trial name
- NCT05631379
- Testing
- Measurement of body composition with computed tomography (CT), GLIM malnutrition criteria, EWGSOP2 sarcopenia criteria
- Where
- Slovenia
- Volunteers
- 100 people
- Sponsor
- Institute of Oncology Ljubljana
Intestinal Metaplasia, Metabolic Syndrome
Oxidative Stress in Intestinal Metaplasia and Metabolic Syndrome
Intestinal metaplasia is generally considered a precancerous lesion. Although it is associated with a very small increase of gastric cancer risk, European Endoscopic Society and other European academic companies highlighted the…
- Conditions
- Intestinal Metaplasia, Metabolic Syndrome, Oxidative Stress, Inflammatory Response
- Trial name
- NCT02695186
- Testing
- Gastroscopy
- Where
- Greece
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- General Hospital of Filiates
Lifestyle Risk Reduction, Rheumatoid Arthritis
Lifestyle Intervention for Rheumatoid Arthritis
The main purpose of this study is to assess whether adding a multifaceted lifestyle intervention to the standard best practice of care can be more effective than standard best practices alone for treating Rheumatoid Arthritis.
- Trial name
- NCT05554705
- Testing
- Intensive Lifestyle intervention
- Where
- United States
- Volunteers
- 114 people
- Sponsor
- Blue Cross Blue Shield of Vermont
Inflammatory Response, Radiculopathy
Inflammatory Markers in Lumbar Radicular Pain Treated With PRF and TFESI
This retrospective observational study aims to evaluate the predictive value of systemic inflammatory markers in determining treatment response in patients with lumbar radicular pain treated with a combination of pulsed…
- Conditions
- Inflammatory Response, Radiculopathy, Radiculopathy Lumbar, Chronic Pain
- Trial name
- NCT07495566
- Testing
- Lumbar Dorsal Root Ganglion Pulsed Radiofrequency
- Where
- Turkey (Türkiye)
- Volunteers
- 264 people
- Sponsor
- Ankara Etlik City Hospital
Sepsis
Indicators of Inflammation and Coagulation in Sepsis
We will collect blood samples from patients with the diagnosis of sepsis and other ICU patients. We will describe the course of different mediator levels and organ injury markers and follow their progression throughout the course…
- Trial name
- NCT01128283
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- University of Oklahoma
Healthy
Punicalagin and Hydroxytyrosol Mixture on Different Inflammatory Markers
A crossover trial was carried out in healthy volunteers aged 45-70 years and BMI <30 kg/m2. Subjects consumed a Antioxidant Supplement (AS) containing 65 mg of punicalagin mixed with 3.3 mg of hydroxytyrosol 3 times daily or a…
- Trial name
- PROBELTEII (NCT02042742)
- Testing
- punicalagin and hydroxytyrosol mixture, Control supplement (maltodextrin)
- Where
- Spain
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Instituto de Investigación Hospital Universitario La Paz
Septic Shock
Characterization of Hemostatic Disordres in Septic Shock: Searching for Biological Markers
Sepsis induces hemostatic disorders due to the exessive or inappropriate activation of inflammation, which could lead either to hypercoagulability or hypocoagulability.
- Trial name
- COASEPT (NCT02692053)
- Testing
- blood sampling
- Volunteers
- 50 people
- Sponsor
- Central Hospital, Nancy, France
Diabetes Mellitus, Type 2, Pediatric Obesity
Association Between Irisin, Inflammatory Markers and Metabolic Status in Obese Children With Type 2 Diabetes Mellitus
The objective of this study was to investigate the association of irisin with inflammatory markers as well with metabolic and anthropometric parameters in children and adolescents with type 2 diabetes mellitus compared with…
- Trial name
- NCT03767608
- Where
- Mexico
- Volunteers
- 40 people
- Sponsor
- Instituto Tecnologico y de Estudios Superiores de Monterey