Clinical trials: Inflamation
Prostatitis, Chronic Prostatitis With Chronic Pelvic Pain Syndrome
Laparoscopic Prostatectomy for Chronic Prostatitis
Prostatitis is an inflammation of the prostate, an pelvic organ of men. Prostatitis can cause great discomfort which varies but can include pelvic pain, pelvic pressure, a vague sense of discomfort, a feeling of malaise and…
- Trial name
- NCT00775515
- Testing
- laparoscopic prostatectomy
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- The Krongrad Institute
Prediabetes, Obesity & Overweight
Human Pilot Study for the Investigation of the Role of Bilberry and Olive Bioactives on Oxidative Stress Parameters and Inflammatory Markers.
Numerous plant-based foods contain bioactive compounds, in particular polyphenols, which have antioxidant, anti-inflammatory, and metabolic regulatory effects.
- Conditions
- Prediabetes, Obesity & Overweight, Inflamation, Oxidative Stress
- Trial name
- BIOTRANSFORM (NCT07659028)
- Testing
- supplementation, food
- Where
- Greece
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National and Kapodistrian University of Athens
Critical Illness, Sepsis
Systemic Immune-Inflamation Index and Mortality in ICU Patients
Systemic Immune-Inflammation Index (SII) is a hemogram-derived biomarker reflecting the balance between systemic inflammation and immune response.
- Trial name
- NCT07493759
- Testing
- Systemic Immune-Inflammation Index (SII)
- Where
- Turkey (Türkiye)
- Volunteers
- 570 people
- Sponsor
- Ataturk University
Primary Stability of the Implants, Pain
Osteoimplant and Dental Implants Stability
Based on the scientific evidence, the relevance of this subject, we consider this study to be justified, the general or specific objective of which is as follows: 'To evaluate the effect of the administration of Osteoimplant© and…
- Trial name
- OIMP (NCT06657521)
- Testing
- osteoimplant
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universidad de Granada
Subjects With Hyperlipidemia, Dyslipidemia
Effects of Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) Inhibition on Arterial Wall Inflammation in Patients With Elevated Lipoprotein(a) (Lp(a))
A study to assess the effects of proprotein convertase subtilisin/ kexin type 9 (PCSK9) inhibition on the arterial wall inflammation in patients with elevated lipoprotein(a).
- Trial name
- ANITSCHKOW (NCT02729025)
- Testing
- Evolocumab
- Where
- 15 sites in United States, Canada and 1 more
- Volunteers
- 129 people
- Sponsor
- Amgen
Muscle Recovery, Oxidative Stress
Development of a Coffee Pulp Infusion as a Strategy for Recovery After Moderate Physical Exercise in a Healthy Population.
The goal of this clinical trial is to learn if a coffee pulp infusion works to improve muscle recovery after moderate physical exercise in a healthy adult population.
- Conditions
- Muscle Recovery, Oxidative Stress, Inflamation, Muscle Damage
- Trial name
- COPULP-REC (NCT07875699)
- Testing
- Two 250 mL infusions per day (one in the morning and one at night) for 45 consecutive days.
- Where
- Spain
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- David Ramiro Cortijo
Secondhand Smoke Exposure, Children
Evaluation of Periodontal Health, Salivary Cotinine and S100A8/A9 Levels in Children Exposed to Passive Smoking
The periodontal health of children exposed to passive smoking will be evaluated by S100A8 and S100A9 levels.
- Conditions
- Secondhand Smoke Exposure, Children, Inflamation, Cotinine Levels
- Trial name
- NCT06791707
- Where
- Turkey (Türkiye)
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- Cumhuriyet University
Wisdom Teeth
Different Inflammatory Biomarkers With Surgical Removal of Mandibular Third Molars
Removal of mandibular third molars (M3s) is the most frequently performed surgical intervention undertaken in dentistry. The indications and timing of surgical removal of M3s has been a matter of international and national…
- Trial name
- NCT05962593
- Testing
- Telephone call
- Where
- Denmark
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Endothelial Function, Oxidative Stress
Black Forest Cocoa Flavanol Supplementation and Health Trial
This randomized, double-blind, controlled clinical trial will evaluate the effects of daily cocoa flavanol supplementation on vascular and inflammatory biomarkers in healthy adult men aged 30 to 75 years.
- Conditions
- Endothelial Function, Oxidative Stress, Inflamation, Vascular Health
- Trial name
- NCT07747714
- Testing
- Cocoa Flavanol Supplement, Low-Flavanol Control Powder
- Where
- 2 sites in United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- The Black Forest LLC
Rheumatic Arthritis, Rheumatoid Arthritis (RA) Prevention
Efficacy and Safety of Resveratrol in Patients With Rheumatoid Arthritis.
The aim of the current study is to evaluate the effects of resveratrol on the clinical outcome(s) of patients with moderate rheumatoid arthritis. Objectives : 1.
- Conditions
- Rheumatic Arthritis, Rheumatoid Arthritis (RA) Prevention, Inflamation, Antioxidant
- Trial name
- NCT07089381
- Testing
- Resveratrol 1 gm., Methotrexate
- Where
- Egypt
- Volunteers
- 118 people
- Sponsor
- Ain Shams University
Critical Illness, Geriatric Patient
Dynamic Inflammatory Changes and Nutritional Risk Scores in ICU Patients Aged 65 Years and Older
"This prospective observational study aims to evaluate the prognostic value of dynamic changes in the serum uric acid-to-albumin ratio (UAR) measured on admission (Day 0) and on Day 3, along with mNUTRIC and PNI scores, regarding…
- Conditions
- Critical Illness, Geriatric Patient, Mortality, Inflamation
- Trial name
- NCT07888010
- Testing
- Uric Acid to Albumin Ratio (UAR) and Nutritional Risk Scores
- Where
- Turkey (Türkiye)
- Volunteers
- 224 people
- Sponsor
- Ankara Etlik City Hospital
Stress (Psychology), Inflamation
A Mindfulness-Based Intervention to Reduce Stress Through the Cultivation of Loving-Kindness, Compassion, Joy, and Equanimity in Healthcare Professionals
Nearly 50% of the adult workforce experience adverse psychological symptoms (e.g., stress, depression, burnout, etc.) stemming from workplace stressors, with healthcare workers experiencing rates as high as 80%.
- Conditions
- Stress (Psychology), Inflamation, Psychosocial Functioning
- Trial name
- FIERCE (NCT07283744)
- Testing
- Building Emotional Strength Training
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Solid Carcinoma
Study of Blood Immune Cells in Cancer Patients Compared to Controls
Tumors have a systemic immune modifying effect. They affect the immune system similarly to states of chronic inflammation and these effects can: be monitored through analysis of nk t and myeloid cells mainly through studies of…
- Trial name
- NCT01312701
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Endothenial Dysfunction, Iron Status
Inflamation, Gut Leakage, Iron Status After 6000m Ergometer Test in Elite Rowers.
The influence of a 6000m ergometer test on the markers of gut injury, endotoxemia, iron status, stress and inflammation in elite rowers.
- Conditions
- Endothenial Dysfunction, Iron Status, Oxidative Stress
- Trial name
- 6000m (NCT06890741)
- Testing
- exercise test
- Where
- Poland
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Poznan University of Physical Education
Peri-implantitis, Soft Tissue Augmentation at Dental Implants
Adjunctive Keratinized Mucosa Augmentation in Peri-Implantitis
This study aims to increase the width and thickness of peri-implant keratinized mucosa (KM) by transferring a properly dimensioned free gingival graft (FGG) from the palatal donor site and to evaluate its effect as an adjunctive…
- Trial name
- NCT07471386
- Testing
- Submucosal debridman + saline irrigation, Free gingival graft surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Gazi University
Inflamation, Hemodialysis
Effect of Sertraline on Inflammation in Hemodialysis Patients with Depression: a Randomized Controlled Trial
Depression is a common mental health condition among patients undergoing hemodialysis and is associated with a lower quality of life, poor treatment adherence, and worse overall health outcomes.
- Conditions
- Inflamation, Hemodialysis, End Stage Renal Disease on Hemodialysis (Diagnosis)
- Trial name
- NCT06840379
- Testing
- Sertraline (Oral Antidepressant)
- Where
- Pakistan
- Volunteers
- 62 people
- Sponsor
- Nishtar Medical University
Achilles Tendon Rupture, Immobilization
Metabolic Complications Following Achilles Tendon Rupture - A Cohort Study
Introduction This study will evaluate the effect on glucose, lipid and bone metabolism following conservative orthopaedic procedures in patients who suffered from acute Achilles tendon rupture.
- Trial name
- NCT02531750
- Testing
- Immobilization due to an Achilles tendon rupture
- Where
- Denmark
- Volunteers
- 14 people
- Sponsor
- Hvidovre University Hospital
Schizophrenia, Cognitive Dysfunction
Supportive Psychotherapy as Adjunct to Risperidone for Cognitive Function and Inflammation in Schizophrenia
This study examined whether adding structured supportive psychotherapy to risperidone treatment is more effective than risperidone alone in improving cognitive function and reducing inflammation in patients with schizophrenia.
- Conditions
- Schizophrenia, Cognitive Dysfunction, Inflamation
- Trial name
- SUPPORT-SCZ (NCT07477301)
- Testing
- Structured Supportive Psychotherapy, Risperidone 2 mg
- Where
- Indonesia
- Volunteers
- 46 people
- Sponsor
- Hasanuddin University
Multiple Sclerosis, Periodontitis
Periodontal Health Profile in Multiple Sclerosis Patients
This study aims to evaluate the periodontal status of patients with Multiple Sclerosis (MS) through clinical, microbiological, and biochemical parameters.
- Trial name
- NCT07412431
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Radiotherapy, Inflamation
Effects of Moderate-intensity Interval Aerobic Exercise (MIIAE) on Inflammatory, Immune, Metabolic, Physical Fitness, and Quality of Life Parameters in Breast Cancer Patients Undergoing Radiotherapy.
Breast cancer and its treatment with radiotherapy may be associated with systemic inflammatory, hematological, cardiac, body composition, functional and quality-of-life alterations.
- Conditions
- Radiotherapy, Inflamation, Immune System, Physical Fitness
- Trial name
- NCT07583719
- Testing
- Moderate-Intensity Interval Aerobic Exercise
- Volunteers
- 40 people
- Sponsor
- Universidad Francisco de Vitoria