Clinical trials: Infertility and Miscarriage
Chronic Endometritis
Efficacy of Dead Sea Peloid Gel in Chronic Endometritis
This study evaluates the effect of Dead Sea Peloid Gel in the treatment of Chronic Endometritis in women with reproductive disorders.
- Trial name
- NCT02680275
- Testing
- Dead Sea Peloid Gel
- Where
- Russia
- Volunteers
- 30 people
- Sponsor
- Scientific Center for Family Health and Human Reproduction Problems, Russia
Infertility, Implantation Failure
ISM1 Versus EmbrioGen Media for Embryo Culture With Previous Failure Implantation in ART Treatments
Recently, it has been suggested that culture of embryos in EmbryoGen medium can increase the live birth rate in IVF patients with a previous history of pregnancy loss.
- Trial name
- NCT01689454
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Biogenesi
Polycystic Ovarian Syndrome, Infertility, Female
Spontaneous Reproductive Outcomes After Oral Inositol Supplementation in Infertile Polycystic Ovarian Syndrome Women.
Polycystic ovarian syndrome (PCOS) is a heterogeneous, multifaceted and complex disorder characterized by insulin resistance (IR), hyperinsulinemia, and hyperandrogenism leading ovarian disfunction and infertility.
- Trial name
- IROP-1 (NCT03598374)
- Testing
- Inositol + Folic acid, Folic acid, Regular intercourses
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Università degli Studi dell'Insubria
Infertility, Miscarriage
International NaProTechnology Evaluation and Surveillance of Treatment for Infertility and Miscarriage (iNEST)
NaProTechnology (NPT) is a treatment option for infertility or miscarriage that identifies issues in a couple's fertility and fixes them to the extent possible by medical intervention.
- Trial name
- iNEST (NCT01363596)
- Testing
- Creighton Model System in conjunction with Natural Procreative Technology (NPT)
- Where
- 8 sites in United States, Canada and 2 more
- Volunteers
- 834 people
- Sponsor
- University of Utah
Infertility, Recurrent Implantation Failure
Effect of Reproductive Tract Microbiota on Pregnancy Outcome in IVF/ICSI
A single center，observational cohort study to explore the relationship between reproductive tract microbiota and pregnancy outcome in the patients accepted IVF/ICSI.
- Conditions
- Infertility, Recurrent Implantation Failure, Recurrent Miscarriage
- Trial name
- NCT04293068
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Peking University Third Hospital
Adenomyosis, Infertility
Adenomyosis and Pregnancy Outcomes in Women Undergoing Assisted Reproductive Technology Treatment
Rationale: A rising number of adenomyosis cases are being diagnosed in women in the age group of 30 to 40 years. This is due to a combination of better diagnostic imaging techniques and a higher number of women delaying the…
- Conditions
- Adenomyosis, Infertility, ART, Pregnancy Loss
- Trial name
- AdAPT-ART (NCT05418140)
- Testing
- Ultrasound diagnosis of adenomyosis
- Where
- 9 sites in United Kingdom
- Volunteers
- 828 people
- Sponsor
- CARE Fertility UK
Infertility, Miscarriage
A Trial of Sperm Injection (PICSI) on Miscarriage Rates in Assisted Conception
Physiological intracytoplasmic sperm injection (PICSI) is a technique used to select healthy, mature sperm for use in infertility treatment based on their physiological ability to bind to hyaluronan (HA), a natural compound found…
- Trial name
- PICSI (NCT05762770)
- Testing
- PICSI
- Where
- United Kingdom
- Volunteers
- 140 people
- Sponsor
- Shrewsbury and Telford Hospitals NHS Trust
Infertility, Female, First Trimester Spontaneous Abortion
Determination of Circulating Placental Biomarkers Levels to Predict the Pregnancy Outcome of First Trimester After IVF.
This study will assess the predictive potential of circulating placental biomarkers for spontaneous miscarriage within the following month in an IVF setting.
- Trial name
- NCT04387994
- Testing
- Blood samples collection
- Where
- Portugal
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Instituto Valenciano de Infertilidade de Lisboa
Infertility
Prevalence of Uterine Malformations in Newly Married Unselected Population
Uterine malformation is occur due to the abnormal development of Mullerian canal during embryogenesis and it is known that it reduces the fertility and live birth rate and also increases the abortion and preterm birth rate.
- Trial name
- NCT04686227
- Testing
- 3D Ultrasound
- Where
- Turkey (Türkiye)
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Infertility and Miscarriage
Natural Procreative Technology Evaluation and Surveillance of Treatment for Infertility and Miscarriage
This study involves research, and the purpose of this study is to evaluate live birth rates among couples who are treated by Natural procreative technology, (NPT) for infertility and miscarriage.
- Trial name
- Fertility (NCT02925390)
- Volunteers
- 46 people
- Sponsor
- St. Louis University
Vaginosis, Bacterial, Infertility
Efficacy Study of Preconception Treatment of an Asymptomatic Bacterial Infection in an Infertility Population
Bacterial vaginosis (BV) is a common vaginal infection characterized by a pathologic shift in the normal vaginal flora. BV has been associated with a number of poor reproductive outcomes, including infertility, preterm labor and…
- Conditions
- Vaginosis, Bacterial, Infertility, Miscarriage
- Trial name
- NCT01322971
- Testing
- Metronidazole
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Stanford University
Infertility, Recurrent Pregnancy Loss
Comparison of Standard ART Practice vs. Trophectoderm Biopsy and Whole Chromosome Analysis
We propose to perform a clinical randomized trial to evaluate the effect of blastocyst biopsy and whole chromosome analysis by Next Generation Sequencing (NGS) in comparison to standard Assisted Reproductive Technologies (ART)…
- Trial name
- NCT01946945
- Testing
- Next Generation Sequencing after Blastocyst biopsy
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- Reprogenetics
Infertility, Recurrent Pregnancy Loss
Preimplantation Genetic Diagnosis Using Blastocyst Biopsy and Array CGH
The investigators propose to perform a clinical randomized trial to evaluate the effect of single embryo (blastocyst) transfer (SET) with array CGH for the evaluation of the complete chromosome complement of the blastocyst in…
- Trial name
- NCT01546350
- Testing
- PGD
- Where
- 4 sites in United States
- Volunteers
- 200 people
- Sponsor
- Reprogenetics
Recurrent Miscarriage, Infertility
Iron Status in Female Infertility and Recurrent Miscarriage
Multiple studies suggest a link between the iron status and the development of the endometrium. Therefore, a sufficient iron supply seems to relevant for female fertility and reproduction.
- Conditions
- Recurrent Miscarriage, Infertility, Iron-deficiency
- Trial name
- NCT05034250
- Testing
- Blood sample
- Where
- Austria
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna