Clinical trials: Infertility Female
The Investigators Collected 534 PCOS Patients as the Case Group,and 580 Infertile Women With Normal Ovulatory Cycle of the Control Group;, At the Same Time, the Investigators Continuedly Collect Cases to October 2012, and Totally Collected 579 Patients With PCOS Altogether;
The Potential Biochemical Diagnosis Criteria and Therapeutic Effect Indexes: Sex Hormone Binding Globulin Levels and Free Androgen Index in Blood of Patients With Polycystic Ovary Syndrome
To explore whether Free androgen index（FAI）can be regarded as biochemically diagnostic indexes of high androgen hormone in blood of patients with Polycentric ovary syndrome（PCOS）.
- Conditions
- The Investigators Collected 534 PCOS Patients as the Case Group,and 580 Infertile Women With Normal Ovulatory Cycle of the Control Group;, At the Same Time, the Investigators Continuedly Collect Cases to October 2012, and Totally Collected 579 Patients With PCOS Altogether;, 534 Patients in the Cases Group and 580 Women in the Control Group Received no Measures, While 579 Patients Received Drugs;, The Investigators Monitored Basic Indexes in Blood of All the Subjects in This Suvey,and Also Monitored Indexes of 579 Patients After Treatment.
- Trial name
- NCT01784380
- Testing
- Diane-35;metformin;Clomiphene citrate; Human menopausal gonadotropin
- Where
- 2 sites in China
- Volunteers
- 1,159 people
- Sponsor
- Zhongshan Bo Ai Hospital
Infertility
Study Comparing Outcomes Between Conventional IVF and a "Freeze-all"-Strategy in Assisted Reproductive Technology
The purpose of this study is to compare conventional fresh embryo transfer with a "freeze all and transfer later strategy" in assisted reproductive technology in terms of ongoing pregnancy rates, live birth rates as well as…
- Trial name
- NCT02746562
- Testing
- Freeze all
- Where
- 2 sites in Denmark
- Volunteers
- 424 people
- Sponsor
- Anja Bisgaard Pinborg
Leukemia, Long-term Effects Secondary to Cancer Therapy in Adults
Ovarian Damage in Young Premenopausal Women Undergoing Chemotherapy for Cancer
RATIONALE: Comparing results of diagnostic procedures, such as ultrasound, done before, during, and after chemotherapy may help doctors learn about the side effects of chemotherapy and help plan the best treatment.
- Conditions
- Leukemia, Long-term Effects Secondary to Cancer Therapy in Adults, Long-term Effects Secondary to Cancer Therapy in Children, Lymphoma
- Trial name
- NCT00402935
- Testing
- laboratory biomarker analysis, fertility assessment and management, management of therapy complications
- Where
- United States
- Sponsor
- Case Comprehensive Cancer Center
Klinefelter Syndrome
Fertility Preservation in Cases of Klinefelter Syndrome.
Klinefelter Syndrome (KS) is the most common sex chromosomal abnormalities (1/600 newborn males), and is characterized by a hypergonadism hypogonadism.
- Trial name
- FERTIPRESERVE (NCT01918280)
- Testing
- Seminal analyses and testicular biopsy
- Where
- 4 sites in France
- Volunteers
- 141 people
- Sponsor
- Hospices Civils de Lyon
Infertility
Gene Expression Analysis of the Endometrium After Endometrial Biopsy in Fertile Women
The aim of this study is to evaluate the gene expression of the endometrium after an endometrial biopsy in fertile women using Next Generation Sequencing of total RNA.
- Trial name
- NCT02219425
- Testing
- endometrial biopsy
- Where
- Denmark
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Infertility, Infertility, Female
Serum Progesterone Levels on the Day of Frozen Embryo Transfer (FET) and Pregnancy Outcomes
Frozen embryo transfer (FET) cycles have become more common in recent years due to a push towards elective single embryo transfer (SET).
- Conditions
- Infertility, Infertility, Female, IVF
- Trial name
- ProFET (NCT04170517)
- Testing
- Measurement of serum progesterone on the day of FET
- Where
- United Kingdom
- Volunteers
- 402 people, healthy volunteers welcome
- Sponsor
- CARE Fertility UK
Infertility (IVF Patients), Acupuncture
Evaluation of Acupuncture's Effectiveness on Pregnancy Outcomes in Women with Recurrent Implantation Failure RIF: a Large Cohort Study
Title: Evaluating the Effectiveness of Acupuncture on Pregnancy Outcomes in Recurrent Implantation Failure (RIF) Patients Undergoing In Vitro Fertilization (IVF): A Large Cohort Study Objective: This study aims to assess the…
- Trial name
- AcupunctureRIF (NCT06708923)
- Testing
- Intervention Name: Acupuncture Therapy Before and After Embryo Transfer Description: The intervention involves acupuncture therapy performed at two key time points during the IVF cycle: 25 minutes be
- Where
- Vietnam
- Volunteers
- 1,969 people, healthy volunteers welcome
- Sponsor
- Hung Vuong Hospital
Primary Ovarian Insufficiency, Low Ovarian Reserve
Rejuvenation of Premature Ovarian Failure With Stem Cells
The ROSE-1 study is designed to determine the efficacy of bone marrow derived stem cell therapy on ovarian function recovery in subjects with idiopathic and other types of premature or primary ovarian failure (POF or POI) and low…
- Conditions
- Primary Ovarian Insufficiency, Low Ovarian Reserve, Premature Ovarian Failure
- Trial name
- ROSE-1 (NCT02696889)
- Testing
- ROSE-1 Protocol
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- University of Illinois at Chicago
Infertility, Female, Reproductive Sterility
Evaluation of Salivary ELISA for Hormone Monitoring in Donors
In donors or patients undergoing assisted reproduction treatments (ART) it is necessary to closely control ovarian stimulation to monitor the number and size of developing follicles.
- Trial name
- MINT-II (NCT05780489)
- Testing
- Determination of progesterone and oestradiol
- Where
- 2 sites in Spain
- Volunteers
- 200 people
- Sponsor
- Instituto Valenciano de Infertilidad, IVI VALENCIA
Hodgkin's Disease, Cervical Cancer
Psychosocial Impact of Cancer-Related Female Infertility
The success of cancer treatment combined with the trend to delay childbearing is increasing the numbers of women survivors whose childbearing has been interrupted by cancer. For some, treatment has resulted in infertility.
- Conditions
- Hodgkin's Disease, Cervical Cancer, Breast Cancer, Lymphoma
- Trial name
- NCT00386217
- Testing
- Telephone Survey
- Where
- United States
- Volunteers
- 239 people
- Sponsor
- M.D. Anderson Cancer Center
Infertility, Female, Neoplasms
A Study to Evaluate the Effectiveness of a Web-based Tool for Fertility Preservation in Cancer Patients
[Background] The number of young cancer patients is increasing, and they may experience impairment or loss of reproductive function due to cancer treatments such as surgery, radiation therapy, and chemotherapy.
- Trial name
- NCT07038174
- Testing
- Fertility preservation decision aid intervention group
- Volunteers
- 32 people
- Sponsor
- National Cancer Center, Korea
Sub Fertility, Female, Fertility Disorders
Effects of Fasting on Success Rates of Assisted Reproductive Techologies
This exploratory study investigates fasting as a potential supportive therapy for infertility treatment in women undergoing in-vitro-fertilization (IVF) / intracystoplamsatic sperm injection (ICSI)
- Conditions
- Sub Fertility, Female, Fertility Disorders, Fertility Issues, Sub-fertility
- Trial name
- KiWuC (NCT04998591)
- Testing
- Fasting
- Where
- Germany
- Volunteers
- 1 people
- Sponsor
- Charite University, Berlin, Germany
Fibrin Blood Clot, Infertility, Female
Ovarian Hyperstimulation and Fibrin Clot Properties.
The impact evaluation of ovarian hyperstimulation on coagulation and fibrinolysis in infertile women. Comparative analysis between different ovarian stimulation protocols on thrombin formation and efficiency of fibrinolysis in…
- Conditions
- Fibrin Blood Clot, Infertility, Female, Endometriosis
- Trial name
- NCT04166825
- Testing
- fibrin clot properties
- Where
- Poland
- Volunteers
- 300 people
- Sponsor
- Jagiellonian University
Infertility, Female
GEnetic Testing in Elective Single Embryo Transfer (GETSET): A Randomized Clinical Trial
The GETSET trial is a prospective randomized trial designed to evaluate the clinical outcomes of incorporating preimplantation genetic testing for aneuploidies (PGT-A) in elective single embryo transfer in women between 35 and 40…
- Trial name
- GETSET (NCT06141135)
- Testing
- Preimplantation genetic testing for aneuploidy (PGTA)
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- Genomic Prediction Inc.
Polycystic Ovary Syndrome, Non-Alcoholic Fatty Liver Disease
Liver Stiffness And Steatosis Assessment In Women With Polycystic Ovary Syndrome Using Fibroscan
Polycystic Ovary Syndrome (PCOS) is a complex endocrine and metabolic disorder prevalent among women of reproductive age. It is closely associated with insulin resistance, obesity, and metabolic dysfunction, often leading to…
- Trial name
- NCT07027332
- Testing
- FibroScan® (Echosens, Paris, France)
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Subfertility, Assisted Reproduction
Role of Follicular Output Rate in the Prediction of in Vitro Fertilization and Intracytoplasmic Sperm Injection in Women With Unexplained Infertility
300 women with unexplained infertility who are already decided to be treated with ICSI will be recruited from Cairo university hospitals and Dar Al-Teb subfertility centre.
- Trial name
- NCT02154958
- Where
- 2 sites in Egypt
- Volunteers
- 300 people
- Sponsor
- Cairo University
Infertility, Female, Endometrium
The Efficacy and Safety of Collagen Scaffold Loaded With Umbilical Cord Derived Mesenchymal Stem Cells in Infertile Women With Thin Endometrium or Endometrial Scarring
The purpose of the study is to evaluate the safety and effectiveness of the collagen scaffold loaded with umbilical cord derived mesenchymal stem cells (UC-MSCs) in infetile women with thin endometrium or endometrial scarring.
- Trial name
- NCT03592849
- Testing
- UC-MSCs therapy
- Where
- China
- Volunteers
- 20 people
- Sponsor
- The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
Infertility
Pregnancy/Implantation Rates Using a Day 3 Score Versus Graduated Embryo Score Plus a Biochemical Marker (sHLA-G)
Objective: To compare pregnancy rates and implantation rates when embryos are selected based on a single Day 3 (D.3) score vs. a GES score plus sHLA-G expression.
- Trial name
- NCT00680238
- Testing
- Human derived FSH
- Volunteers
- 214 people, healthy volunteers welcome
- Sponsor
- University of Stellenbosch
Infertility, Female
Efficacy of Growth Hormone Supplementation With Gonadotrophins in IVF/ICSI for Poor Responders
The objective of this study is to assess the effectiveness of adjuvant growth hormone injection during controlled ovarian stimulation, in poor responder women undergoing intracytoplasmic sperm injection (ICSI) procedures.
- Trial name
- NCT03759301
- Testing
- Growth Hormones Somatropin Recombinant
- Where
- Egypt
- Volunteers
- 156 people
- Sponsor
- ClinAmygate
ICSI, IVF
Dual Trigger VS HCG Trigger for Final Oocyte Maturation in Normal Responders
To compare the embryological and reproductive outcomes of dual trigger versus conventional hCG trigger for final oocyte maturation in normal responder patients undergoing ICSI cycles.
- Conditions
- ICSI, IVF, Normal Responders, Infertility Assisted Reproductive Technology
- Trial name
- DT-HCG-IVF (NCT07861399)
- Testing
- Dual trigger (human chorionic gonadotropin plus GnRH-agonist), hCG trigger
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Al-Azhar University