Clinical trials: Infertility Assisted Reproductive Technology
Recurrent Implantation Failure
Platelet Rich Plasma and Recurrent Implantation Failure
This study is a randomized controlled clinical trial to compare the pregnancy outcomes of infertile women with recurrent implantation failure.
- Trial name
- NCT03996837
- Testing
- Intra uterine infusion of platelet rich plasma
- Where
- Iran
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Royan Institute
Infertility, Pregnancy
Sexual Absorption of Vaginal Progesterone
The purpose of this study is to determine if sexual intercourse lowers serum progesterone in women using vaginal progesterone gel (Crinone®), and increases serum progesterone in their male sexual partners.
- Trial name
- NCT01959464
- Testing
- Crinone vaginal progesterone gel
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Sterility, Infertility
Myo-Inositol- Based Co-treatment in Women With PCOS Undergoing Assisted Reproductive Technology
This is a prospective comparative randomized controlled study investigating the effect of Myo-Inositol-based co-treatment on oocyte quality measures in women with PCOS.
- Trial name
- NCT03177122
- Testing
- Myo-inositol
- Where
- Lebanon
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- American University of Beirut Medical Center
Environmental Exposure, Assisted Reproductive Technology
Environmental and Behavioral Factors in Infertility and ART Outcomes
This large-scale study aims to understand how everyday environment and lifestyle may affect the success of fertility treatments like IVF.
- Conditions
- Environmental Exposure, Assisted Reproductive Technology, Prospective Study
- Trial name
- NCT07384676
- Testing
- plastic products, None exposure
- Where
- China
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- The Third Xiangya Hospital of Central South University
Infertility, Subfertility
The Microbiome in Subfertility and Assisted Reproductive Technologies (ART)
To assess the impact of the female genital microbiome on ART outcome.
- Trial name
- NCT03105453
- Testing
- 3 Sampling points
- Where
- Belgium
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
Anxiety, Assisted Reproductive Treatments
Virtual Reality for Anxiety Relief in Infertile Women
This study examines the impact of virtual reality (VR) applications on anxiety levels before and after embryo transfer procedures.
- Conditions
- Anxiety, Assisted Reproductive Treatments, Women, VR
- Trial name
- NCT07020975
- Testing
- VR Glasses
- Where
- Cyprus
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Cyprus Aydin University
Controlled Ovarian Stimulation
To Compare and Evaluate the Efficacy and Safety of Ganilever PFS(Prefilled Syringe) and Orgalutran®
to compare and evaluate the efficacy and safety of Ganilever PFS and Orgalutran® in infertility women for assisted reproductive technologies
- Trial name
- NCT03051087
- Testing
- Ganirelix acetate
- Where
- 2 sites in South Korea
- Volunteers
- 255 people, healthy volunteers welcome
- Sponsor
- LG Life Sciences
Infertility, Female
Exploratory Study Assessing Synchronisation of Egg Sacs With Degarelix
The main purpose of this clinical research study is to investigate if degarelix can synchronise the growth of the egg sacs in the ovaries and if degarelix has any effect on the lining of the womb.
- Trial name
- NCT00434122
- Testing
- Degarelix mid-luteal, 2.5 mg
- Where
- 4 sites in Belgium, Czechia and 1 more
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Ferring Pharmaceuticals
Reproductive Health, Time to Pregnancy
Reproductive Health of Couples of Childbearing Age: a Community Based Prospective Cohort Study
This community based prospective cohort study was established to investigate the fecundability of couples of childbearing age. Data are collected regarding age, body mass index, education, menstrual regularity as well as…
- Conditions
- Reproductive Health, Time to Pregnancy, Infertility, Risk Factor
- Trial name
- ReH-CP (NCT04068428)
- Where
- 4 sites in China
- Volunteers
- 2,313 people, healthy volunteers welcome
- Sponsor
- Guangzhou Women and Children's Medical Center
Maternal Cardiometabolic Health, Infertility
St Mary's Assisted Reproductive Technology and Cardiometabolic Health: Modifiable Targets for Multimorbidity Prevention (START-HEALThY)
The main causes of death in women are conditions affecting the heart and blood vessels (cardiovascular disease, CVD). Women who have difficulties getting pregnant (infertility) may be at increased risk, but the reasons for this…
- Conditions
- Maternal Cardiometabolic Health, Infertility, Assisted Reproductive Technology, Cardiovascular Health
- Trial name
- START-HEALThY (NCT07173569)
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University of Manchester
Patient Satisfaction
The Use of an Online Learning and Consent Platform in Infertility Treatment
The primary purpose of this study is to objectively assess if interactive multimedia tutorials (online videos) enhances patients' comprehensive understanding of assisted reproductive technology (ART) adding EngagedMD, an online…
- Trial name
- NCT03962257
- Testing
- EngagedMD online learning platform
- Where
- 3 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Infertility
Sexual Intercourse and Vaginal Absorption of Progesterone
The objective of this project is to compare the vaginal absorption of progesterone administered in the vaginal ovum by measuring progesteroneemia in 3 situations (or "sexual event"): abstinence, sex protected by condoms and…
- Trial name
- SexVAP (NCT05232344)
- Testing
- Estradiol / Progesterone, Sexual event
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Infertility
The Effect of Sacral Surface Electrical Stimulation for Assisted Reproductive Technology
The purpose of this study is to determine whether sacral surface electrical stimulation is effective in the treatment of assisted reproductive technology.
- Trial name
- SSE (NCT01082913)
- Testing
- SSE
- Where
- Japan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Shiga University
Infertility Assisted Reproductive Technology
Association Between Serum Progesterone Levels on Embryo Transfer Day and Clinical Pregnancy in Frozen-thawed Embryo Transfer Cycles Using Hormone Replacement Therapy
A retrospective evaluation of routinely collected clinical, embryological, laboratory, and pregnancy outcome data provides an efficient approach to examine the association between serum progesterone on the day of FET and clinical…
- Trial name
- NCT07858227
- Testing
- data collection
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Beta-hCG Positivity, Clinical Pregnancy
Evaluation of Assisted Reproductive Technology (ART) Outcomes in Couples With Nonobstructive Azoospermia, Cryptozoospermia, and Severe Oligozoospermia
This study aims to compare the In Vitro Fertilization (IVF/ICSI) outcomes of patients with a sperm concentration of <5 million/mL (severe oligozoospermia) and <1 million/mL (cryptozoospermia) to those diagnosed with…
- Conditions
- Beta-hCG Positivity, Clinical Pregnancy, Miscarriage, Multiple Pregnancy
- Trial name
- ART (NCT07897279)
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Duzce University
Infertility, Female
Effects of Physical Activity and Fitness, Cardiovascular- and Psychosocial Health on Medically Assisted Reproduction
This prospective observational study aims to investigate the association between physical activity and clinical pregnancy rates in women undergoing medically assisted reproduction.
- Trial name
- REPRO-FIT (NCT07321665)
- Testing
- Health, fitness and lifestyle assessment
- Where
- Switzerland
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Infertility in Women Undergoing Assisted Reproductive Treatment, Infertility
Gamified Healthy Lifestyle Training in Women Undergoing Assisted Reproductive Treatment
Objective: A prospective randomized controlled trial with a pretest-posttest design was planned to evaluate the effects of a gamified healthy lifestyle behaviors training intervention using the D6 model, to be administered to…
- Conditions
- Infertility in Women Undergoing Assisted Reproductive Treatment, Infertility, Assisted Reproductive Technology, Health Lifestyle Behaviors
- Trial name
- NCT07460661
- Testing
- Gamified Healthy Lifestyle Education+Digital Healthy Lifestyle Education Booklet, Digital Healthy Lifestyle Education Booklet
- Where
- Turkey (Türkiye)
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Marmara University
Infertility
Environment and Reproductive Health; Human Exposure to Bisphenol A, Phthalates and Fertility and Pregnancy Outcomes
The purpose of the study is to investigate the relationship between environmental agents and reproductive health. Environmental agents of interest include exposure to chemicals such as polychlorinated biphenyls (PCBs), flame…
- Trial name
- EARTH (NCT00011713)
- Testing
- Completion questionnaires/providing biological samples
- Where
- United States
- Volunteers
- 1,474 people, healthy volunteers welcome
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Infertility, Female
Junctional Zone and Its Relation to Outcomes in Assisted Reproductive Technology
The junctional zone (JZ) is an internal layer of the myometrium, with unique characteristics that allow its visualization as a hypoechogenic structure in three-dimensional (3D) ultrasound.
- Trial name
- NCT04878224
- Where
- Portugal
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Centro Hospitalar Lisboa Norte
Infertility, Assisted Reproductive Technology
Does the Embryo Transfer Technique Affect the Success of in Vitro Fertilization?
Prospective, open, randomized, parallel, two-arm trial to compare the clinical pregnancy rate between most commonly used two embryo transfer techniques: trial followed by transfer technique and afterloading technique
- Conditions
- Infertility, Assisted Reproductive Technology, IVF
- Trial name
- NCT03756857
- Testing
- Afterload Transfer, Trial followed by transfer
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Acibadem Kadiköy Hospital