Clinical trials: Infertility
Ovarian Failure, Thyroid Diseases
Thyroid Function and Autoimmunity in Subfertility Women and Assisted Reproductive Therapy
The assessment of ovarian reserve is well established based on the dosage of anti-Mullerian hormone (AMH). The clinical applicability of detecting thyroid autoantibodies levels has been discussed as a potential marker of…
- Trial name
- NCT06394466
- Testing
- Non Applicable
- Where
- Brazil
- Volunteers
- 453 people, healthy volunteers welcome
- Sponsor
- Rio de Janeiro State University
Infertility, Female
CAPA In-vitro Oocyte Maturation (CUHK Medical Centre Limited)
In vitro oocyte maturation (IVM) is a mild-approach assisted reproductive technology (ART). Because of its simplicity, the more favorable financial implications (reduced cost) for patients, and the lower health risk profile of…
- Trial name
- NCT07083427
- Testing
- CAPA-IVM
- Where
- Hong Kong
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Primary Ovarian Insufficiency, Unexplained Infertility
Study of Oral Dehydroepiandrosterone(DHEA) to Treat Previously Unexplained Infertility
The experimental focus of this project is on the interaction of DHEA treatment on pregnancy in women with otherwise unexplained infertility and evidence of premature ovarian aging (POA).
- Trial name
- DHEAFert (NCT00650754)
- Testing
- Dehydroepiandrosterone
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Center for Human Reproduction
Infertility
Sperm Selection for Infertility Treatment (SSA)
Infertility is considered a disease by the World Health Organization and it is increasing worldwide affecting more than 70 million couples. About 50% of the cases are due to male inability to fertilize the oocyte.
- Trial name
- SSA (NCT02867111)
- Testing
- Sperm Selection Assay, Attractant Substance, ICSI
- Where
- 2 sites in Argentina
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Universidad Nacional de Córdoba
Infertility
Use of High Cost Monitoring During Letrozole Ovulation Induction
The purpose of this study is to investigate monitoring methods during ovulation induction cycles with letrozole and their effect on pregnancy rates.
- Trial name
- NCT01279200
- Testing
- Midcycle ultrasound + hCG injection, Urinary LH kits
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Covid19, Fertility Issues
Prospective Two-arm Study of Fertility in Men With COVID-19
COVID-19 infection is hypothesized to have a potentially negative effect on male fertility through direct damage to the testes. The current trial is aimed at investigating the effect of SARS-CoV-2 on fertility and determining if…
- Trial name
- NCT04716179
- Testing
- Sperm test, hormone levels (testosterone, FSH, LH, prolactin), SARS-CoV-2 Ig G levels
- Where
- Russia
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- I.M. Sechenov First Moscow State Medical University
Infertility
IUI vs. IVF/ICSI in Women Aged 38-42 Years: a Prospective Randomized Controlled Trial.
Prospective randomised controlled trial: 3 IUI cycles versus 1 IVF/ICSI cycle in women aged 38-42 years.
- Trial name
- NCT01992731
- Testing
- Drug: Follitropine Bèta
- Where
- Belgium
- Volunteers
- 138 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
Erectile Dysfunction, Azoospermia
Trial to Evaluate Erectile Function, Fertility and Sperm Count in Male Cyclists Compared to Age Matched Controls
Bicycle riding is associated with related diverse urogenital symptoms ranging from genital numbness to erectile dysfunction (ED).
- Trial name
- NCT00282477
- Where
- Israel
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
OVARIAN STIMULATION, Infertility
Pharmacokinetics of FSH and hCG After a Single Subcutaneous Injection of Gonadotropins-IBSA
The objectives of this study is to evaluate the PK and the dose-proportionality of FSH and HCG following a single dose of Gonadotropins-IBSA, administered subcutaneously.
- Trial name
- NCT06781957
- Testing
- Gonadotropins Subcutaneos
- Where
- Canada
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- IBSA Institut Biochimique SA
Infertility
Elonva in Combination With Hp-FSH Versus Elonva With Low Dose hCG
The study compares in a randomized controlled way two stimulation methods. One of these stimulation methods implements a new insight in ovarian follicular growth.
- Trial name
- NCT03208972
- Testing
- low dose hCG, hp-FSH, Corifollitropin Alfa
- Where
- Belgium
- Volunteers
- 107 people, healthy volunteers welcome
- Sponsor
- AZ Jan Palfijn Gent
Azoospermia
Obtaining Undifferentiated Cells From Testis Biopsy
The purpose of this study is to isolate and culture stem cell from adult human testicular biopsies for future transplantation in fertility preservation.
- Trial name
- NCT01375062
- Testing
- analyse and proliferate the cells
- Where
- Spain
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Igenomix
Chorioamnionitis
Intrapartum Study of Sterile and Clean Gloves
The purpose of this study is to determine whether the use of sterile or clean gloves during labor exams affects the rate of chorioamnionitis. Chorioamnionitis is an infection of the membranes around the baby.
- Trial name
- NCT01852188
- Testing
- Type of glove used for intrapartum vaginal exams
- Where
- United States
- Volunteers
- 507 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Oligospermia, Sperm Count, Low
Creatine and Ubiquinol for Sperm Quality
This randomized controlled double-blind parallel-group interventional trial explores the impact of 8-week creatine supplementation, with or without ubiquinol, on sperm quality biomarkers in normospermic and oligospermic men.
- Trial name
- CRESPAQ10 (NCT06202469)
- Testing
- Supplement 1, Supplement 2
- Where
- Serbia
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Novi Sad, Faculty of Sport and Physical Education
Infertility
Cleavage Pattern of Embryos and Oxidative Parameters
To investigate prospectively whether embryos with abnormal cleaving pattern have different oxidative parameters from normally cleaving embryos, and to analyze whether these parameters have an association with demographic…
- Trial name
- NCT03791931
- Testing
- oxidative stress measurement
- Where
- Israel
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Carmel Medical Center
Subfertility
Hormonal Stimulation in IUI Treatment: Is Clomifen Combined With Ethinyl Estradiol Better, Worse or Equal to Menopur
What is the best medication for hormonal stimulation in cycles with high intra-uterine insemination: tablets of Clomifen (5 days) followed by tablets of Ethinyl Estradiol (5 days) or daily injections with Human Menopausal…
- Trial name
- NCT01569945
- Testing
- Clomifen, Ethinyl Estradiol, Menotropins
- Where
- Belgium
- Volunteers
- 371 people, healthy volunteers welcome
- Sponsor
- University Hospital, Gasthuisberg
Infertility, Pregnancy
Lifestyle and Fertility Study on Antioxidant Status, Diet and Early Pregnancy
Researchers believe that certain lifestyle factors can influence a couple's ability to conceive and have a baby. The ISIS Study will look at the health habits of couples who are planning their first pregnancy, and then attempt to…
- Conditions
- Infertility, Pregnancy, Fertility, Nutrition
- Trial name
- NCT00642590
- Where
- 2 sites in United States
- Volunteers
- 266 people, healthy volunteers welcome
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Endometriosis, Endometriosis-related Pain
Metabolomic Profile in Women With and Without Endometriosis
The pathogenesis of endometriosis is very complex as several factors, including genetic, environmental and lifestyle-related factors, are involved in the development, progression and maintenance of the disease.
- Conditions
- Endometriosis, Endometriosis-related Pain, Infertility
- Trial name
- METABOLENDO (NCT05496218)
- Testing
- Blood samples
- Where
- Italy
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Infertility
Luteal Support and Intrauterine Insemination (IUI) With Clomiphene Citrate
The purpose of this study is to assess the effect of luteal phase supplement (LPS) on pregnancy rate in IUI cycles stimulated with clomiphene citrate.
- Trial name
- NCT01046708
- Testing
- micronized progesterone
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
Oligospermia, Teratospermia
Ramipril for the Treatment of Oligospermia
This is a randomized controlled trial to evaluate the effect of ramipril in stimulating and promoting sperm production in men with low sperm count.
- Conditions
- Oligospermia, Teratospermia, Asthenozoospermia, Male Infertility
- Trial name
- NCT01856361
- Testing
- Ramipril
- Where
- United States
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Infertility
Cervical Mucus - the Biochemical and Molecular Properties in Fertile and Subfertile Women (C-MIS Study)
Infertility affects approximately one in six couples1. In approximately one third of cases, there is no cause found as to why a couple are unable to conceive2.
- Trial name
- C-MIS (NCT01678859)
- Where
- Ireland
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Merrion Fertility Clinic
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