Clinical trials: Infertility/Sterility
Infertility
Aspiration of Excessive Endometrial Fluid at the Day of Ovum Retrieval Plus Diosmin in (ICSI) Cycles
To notify the effect of aspiration of excessive endometrial fluid in addition to Diosmin in cases undergoing intracytoplasmic sperm injection (ICSI) cycles.
- Trial name
- NCT02158000
- Testing
- group A
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Benha University
Infertility, Female
hUC Mesenchymal Stem Cells (19#iSCLife®-UT) Therapy for Patients With Thin Endometrial Infertility
To explore the therapeutic effect and safety of human umbilical cord mesenchymal stem cells on thin endometrial infertility and to explore whether human umbilical cord mesenchymal stem cells using collagen as the carrier can…
- Trial name
- NCT05495711
- Testing
- human umbilical cord mesenchymal stem cell complex collagen, intrauterine injection
- Where
- China
- Volunteers
- 25 people
- Sponsor
- Sclnow Biotechnology Co., Ltd.
Recurrent Implantation Failure, Recurrent Pregnancy Loss
Study of Endometrial Immune and Microbiological Modifications in Cases of Recurrent Implantation Failure and/or Recurrent Pregnancy Loss
The IMERR study aims to improve understanding of certain causes of infertility related to recurrent implantation failure (RIF) and/or recurrent pregnancy loss (RPL), conditions that affect many women undergoing assisted…
- Conditions
- Recurrent Implantation Failure, Recurrent Pregnancy Loss, Infertility, Female, Endometrial Diseases
- Trial name
- IMERR (NCT07265505)
- Testing
- Endometrial Biopsy, Vaginal Swab, Blood sample
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Infertility
Reduction of Sperm DNA Fragmentation by Oral Ginger
This study is a randomized, double blind, controlled clinical trials assess the efficacy of the ginger oral treatment on sperm DNA fragmentation, sperm parameters and male hormones.
- Trial name
- NCT02032251
- Testing
- oral administration of ginger
- Where
- Iran
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Royan Institute
Infertile Patients
the Effect of Hyaluronic Acid Intrauterine Wash on Endometrial Receptivity and Pregnancy Outcome
Hyaluronic acid intrauterine wash is done for infertile females undergoing intracytoplasmic sperm injection on the day of oocyte retrieval.
- Trial name
- NCT06937645
- Testing
- Hyaluronic Acid (HA), platlet rich plasma (PRP)
- Where
- Iraq
- Volunteers
- 120 people
- Sponsor
- Al-Nahrain University
Progesterone Levels, Infertility
The Luteal Phase After GnRHa Trigger - a Proof of Concept Study
The purpose of this study is to investigate levels of progesterone in the luteal phase after various stimulations in the follicular phase and treatment with GnRH antagonist protocol followed by GnRHagonist as induction of…
- Trial name
- NCT01504139
- Testing
- hCG(r-hCG, Ovitrelle, Merck-Serono, Hellerup, Denmark) in the late follicular phase + luteal phase, hCG(r-hCG, Ovitrelle,Merck-Serono, Hellerup, Denmark) in the follicular phase + luteal phase, LH(r-LH,Luveris, Merck-Serono, Hellerup, Denmark) in the luteal phase
- Where
- Denmark
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- Regionshospitalet Viborg, Skive
Covid19, Infertility, Male
Impact of the Coronavirus Disease 2019 (COVID-19) on Sperm Parameters
This study aims to better understand the effects of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, virus that causes the coronavirus disease 2019 (COVID-19), on male fertility.
- Trial name
- NCT04937608
- Testing
- Sperm analysis
- Where
- Canada
- Volunteers
- 2 people
- Sponsor
- Fertilys
Infertility
Effectiveness of Estradiol Valerate Pretreatment in Antagonist Protocol for Poor Ovarian Response Patient
The purpose of study is to assess the efficacy of add-on estrogen pretreatment in GnRH antagonist protocol on oocyte retrieval as compared with GnRH antagonist protocol for patients with poor ovarian response Add-on estrogen…
- Trial name
- NCT03300518
- Testing
- Follitropin Beta;MSD, Ganirelix, hCG
- Where
- China
- Volunteers
- 552 people
- Sponsor
- Reproductive & Genetic Hospital of CITIC-Xiangya
Female Infertility
What is the Best Moment for Performing an HSG in Women With a Unfulfilled Childwish
The aim of this study is to determine whether direct tubal flushing with oil-based contrast at HSG incorporated in the fertility work-up results in 10% more ongoing pregnancies and a shorter time to pregnancy, which will…
- Trial name
- H2Oil-timing (NCT05608590)
- Testing
- Lipiodol UltraFluid
- Where
- Netherlands
- Volunteers
- 554 people
- Sponsor
- Amsterdam UMC, location VUmc
Infertility
Comparison of Frozen-thawed Embryo Transfers and Fresh Embryo Transfers With Whole Chromosome Analysis Using Next Generation Sequencing
The investigators propose to perform a clinical randomized trial to evaluate the effect of a frozen-thawed embryo transfer and a fresh embryo transfer on pregnancy and implantation rates; with the added benefit of a blastocyst…
- Trial name
- NCT02000349
- Testing
- PGD
- Where
- United States
- Volunteers
- 186 people
- Sponsor
- Reprogenetics
Subfertility
Corifollitropin Alfa Compared to Daily rFSH in Poor Responders Undergoing ICSI
Corifollitropin alfa has been shown to result in significantly more oocytes compared to daily recombinant follicle stimulating hormone (recFSH) (Devroey et al., 2009), probably due to the higher circulating FSH activity during…
- Trial name
- NCT02046655
- Testing
- Corifollitropin alfa, rFSH
- Where
- Greece
- Volunteers
- 80 people
- Sponsor
- Aristotle University Of Thessaloniki
Infertility
Randomized Trial Comparing EmbryoScope With EmbryoScope+.
The purpose of the study is to compare the current EmbryoScope Time-Lapse System being used in IVF which has become standard of care to the new model EmbryoScope to demonstrate that the EmbryoScope+ is as safe and reliable as the…
- Trial name
- NCT03522350
- Testing
- EmbryoScope, EmbryoScope+
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Weill Medical College of Cornell University
Embryo Transfer, IVF
Effect of Pentoxyfilline on Endometrial Thickness and Frozen Embryo Transfer Outcomes
The aim of this work was to investigate the effect of different vasodilators as pentoxifylline in women with unexplained infertility using IVF
- Conditions
- Embryo Transfer, IVF, Infertility
- Trial name
- NCT07499817
- Testing
- pentoxifylline 400 mg, (control)
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Beni-Suef University
Primary Ovarian Insufficiency, Low Ovarian Reserve
Rejuvenation of Premature Ovarian Failure With Stem Cells
The ROSE-1 study is designed to determine the efficacy of bone marrow derived stem cell therapy on ovarian function recovery in subjects with idiopathic and other types of premature or primary ovarian failure (POF or POI) and low…
- Conditions
- Primary Ovarian Insufficiency, Low Ovarian Reserve, Premature Ovarian Failure
- Trial name
- ROSE-1 (NCT02696889)
- Testing
- ROSE-1 Protocol
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- University of Illinois at Chicago
Infertility
Three-dimensional Versus Two-dimensional Ultrasound Guided Embryo Transfer in Women Undergoing ART Treatment
Objectives: To assess whether embryo transfer guided by three-dimensional ultrasound (3DUS) produces a significantly higher clinical pregnancy rate than embryo transfer guided by two-dimensional ultrasound (2DUS).
- Trial name
- NCT02413697
- Testing
- Two-dimensional ultrasound, Three-dimensional ultrasound
- Where
- Hong Kong
- Volunteers
- 481 people
- Sponsor
- Chinese University of Hong Kong
Male Infertility
Oxidative Stress and Male Infertility.
Study Aims: To evaluate the impact of oxidative and nitrosative stress, as well as DNA methylation, on male reproductive health.
- Trial name
- NCT06210568
- Testing
- no intervention
- Where
- Italy
- Volunteers
- 800 people
- Sponsor
- IRCCS San Raffaele
Infertility, Emotional Disorder
Online Prevention of Emotional Disorders in Women Undergoing Fertility Treatments
The main aim of this pilot study is to study the clinical utility and acceptability of a transdiagnostic psychological intervention, the Unified Protocol, delivered in online format to prevent the onset of emotional disorders in…
- Conditions
- Infertility, Emotional Disorder, Anxiety Depression
- Trial name
- RE-FER moodle (NCT06420674)
- Testing
- Unified Protocol for Transdiagnostic Treatment of Emotional Disorders
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- Jorge Javier Osma López
Infertility, Female
CAPA-IVM Versus STANDARD IVM
The aim of this study is to evaluate the effectiveness and safety of CAPA-IVM versus standard IVM in women with polycystic ovarian morphology (PCOM) or polycystic ovary syndrome (PCOS) .
- Trial name
- NCT03921710
- Testing
- CAPA-IVM, Standard-IVM
- Where
- Vietnam
- Volunteers
- 80 people
- Sponsor
- Mỹ Đức Hospital
Male Infertility
Excision Versus Preservation of Spermatic Cord Lipoma Detected During Subinguinal Varicocelectomy
In the current study, the adult infertile patients with clinical varicoceles will be included. the patients will undergo subinguinal varicocelectomy.
- Trial name
- NCT06257459
- Testing
- subinguinal varicocelectomy
- Where
- Egypt
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Tanta University
Infertility, Weight Loss
Weight Loss on IVF Outcomes in Overweight and Obese Infertile Women
The aim of this study is to determine whether weight loss prior to in vitro fertilization (IVF) improves live birth outcomes in overweight and obese infertile women.
- Conditions
- Infertility, Weight Loss, Obesity, IVF
- Trial name
- NCT07174817
- Testing
- weight loss
- Where
- China
- Volunteers
- 197 people
- Sponsor
- Peking University People's Hospital