Clinical trials: Infectious Endocarditis
Endocarditis
Management of Infectious Endocarditis as Part of a Multidisciplinary Consensus Meeting
New ESC 2015 recommendations with encouragement to set up a Multidisciplinary Consultation Meeting to discuss the medical and surgical management of endocarditis, set up at Strasbourg University Hospital in October 2016: Impact…
- Trial name
- NCT03429153
- Where
- France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Strasbourg, France
Bacteremia, Infective Endocarditis
Impact of the Blood Culture Technique on the Diagnosis of Infective Endocarditis
To evaluate the performance of a single high volume blood culture sampling strategy versus the actually used multiple sampling strategy for the diagnosis and categorization of infective endocarditis according to the Duke-Li…
- Trial name
- UniEndo (NCT03153384)
- Testing
- Blood Culture
- Where
- 8 sites in France
- Volunteers
- 269 people
- Sponsor
- Central Hospital, Nancy, France
Endocarditis, Stroke
Evaluation of the Prognostic Impact of a Neuro-vascular Examination Associated With Cerebral MRI in the Acute Phase of Infectious Endocarditis
Infectious endocarditis (IE) is a serious condition with an annual incidence of 3 to 10 per 100,000 people. Brain infarctions complicate approximately 20-40% of endocarditis.
- Trial name
- POMPEI (NCT05378126)
- Testing
- Neurological assessment
- Where
- France
- Volunteers
- 29 people
- Sponsor
- Hospices Civils de Lyon
Staphylococcus Aureus Infection
Plasma Pharmacological Monitoring of M Penicillins in Methicillin-sensitive Staphylococcus Aureus Bacteremia
The treatment of Methicillin-sensitive Staphylococcus aureus bacteremia is based on the first-line use of cefazolin or M penicillins (oxacillin and cloxacillin).
- Trial name
- DOSESACLOXA (NCT06495697)
- Where
- France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Strasbourg, France
Complicated Skin and Skin Structure Infections and Bacteremia Including Right-sided Endocarditis
Safety and Efficacy Study of CUBICIN (Daptomycin) Under Conditions of Actual Use
The purpose of this study is to monitor the safety and efficacy of CUBICIN under conditions of actual use in patients who are diagnosed with complicated Skin and Skin Structure infection (cSSI) or Staphylococcus aureus bacteria…
- Trial name
- NCT01219114
- Where
- 5 sites in Philippines
- Volunteers
- 200 people
- Sponsor
- AstraZeneca
Bacterial Infections, Bone Diseases, Infectious
Fosfomycin I.v. for Treatment of Severely Infected Patients
The purpose of this European, multicentric, prospective, non-interventional study is to document and evaluate the efficacy and safety of the treatment of severely infected patients with intravenously administered fosfomycin…
- Conditions
- Bacterial Infections, Bone Diseases, Infectious, Osteomyelitis, Central Nervous System Bacterial Infections
- Trial name
- FORTRESS (NCT02979951)
- Where
- 50 sites in Austria, Germany and 3 more
- Volunteers
- 1,000 people
- Sponsor
- Infectopharm Arzneimittel GmbH
Infectious Endocarditis
Hyperbaric Oxygen Treatment in Humans With Gram Positive Cocci Endocarditis
Infectious endocarditis (IE) is defined as an infection anywhere on the endocardium, most often localised to the cardiac valves. It is an infection with an increasing incidence and in Denmark with 6-700 new cases annually.
- Trial name
- ENDOHOT (NCT04691440)
- Testing
- Hyperbaric oxygen
- Where
- Denmark
- Volunteers
- 10 people
- Sponsor
- Ole Hyldegaard
Endocarditis
Suppressive Antibiotic Therapy for Endocarditis
Endocarditis are deadly infections, which nowadays occurs mainly among older patients with multiple comorbidities. The incidence is notably high among patients with valvular prosthetic or implantable devices.
- Trial name
- SATIE (NCT06107309)
- Where
- France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Strasbourg, France
Infective Endocarditis
Predisposition to Infectious Endocarditis
To evaluate the gender-related elements, a first step will be to analyze the impact of sex ratio on different parameters such as age in endocarditis and the type of underlying valvulopathy and other associated comorbidities.
- Trial name
- NCT03979261
- Testing
- evolution of sex ratio according to age
- Where
- France
- Volunteers
- 450 people
- Sponsor
- Assistance Publique Hopitaux De Marseille