Clinical trials: Infarction Cerebral
Brain Ischemia, Acute Stroke
Heart and Ischemic STrOke Relationship studY
Although cardio-embolic etiology of ischemic stroke (IS) is largely respected, there is still no clear recommendation for routine complex cardiological examination in all IS patients.
- Conditions
- Brain Ischemia, Acute Stroke, Heart Diseases
- Trial name
- HISTORY (NCT01541163)
- Where
- Czechia
- Volunteers
- 500 people
- Sponsor
- University Hospital Olomouc
Cerebral Infarction
Human Umbilical Cord Mesenchymal Stem Cell Therapy (19#iSCLife®-CI) for Cerebral Infarction Patients in Convalescent Period.
This is a randomized, double-blind study. Human umbilical cord mesenchymal stem cells (hUC-MSC) will be treated on cerebral infarction patients, and evaluates their neurological function of convalescent period.
- Trial name
- NCT03176498
- Testing
- Allogeneic umbilical cord mesenchymal stem cell, Aspirin Enteric-coated Tablets & Atorvastatin Calcium
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Sclnow Biotechnology Co., Ltd.
Stroke, Stroke, Ischemic
MLC1501 Study Assessing Efficacy in Post STrOke Subjects With mOtor Deficits
This is a multi-center, randomized, double-blind, placebo-controlled trial of MLC1501 in patients with stroke. Eligible participants will be randomized in a 1:1:1 ratio to orally receive MLC1501 high-dose twice a day, MLC1501…
- Conditions
- Stroke, Stroke, Ischemic, Strokes Thrombotic, Stroke Sequelae
- Trial name
- MAESTOSO (NCT05289947)
- Testing
- MLC1501
- Where
- 11 sites in Philippines, Singapore
- Volunteers
- 303 people
- Sponsor
- Moleac Pte Ltd.
Cerebral Infarction
Cilostazol Stroke Prevention Study : A Placebo-controlled Double-blind Trial for Secondary Prevention of Cerebral Infarction.
The multi-center, double-blind, placebo-controlled, randomized, group-comparison study was designated to assess the long-term safety and efficacy of the antiplatelet drug cilostazol in preventing the recurrence of cerebral…
- Trial name
- CSPS (NCT00766545)
- Testing
- cilostazol
- Where
- Japan
- Volunteers
- 1,095 people
- Sponsor
- Otsuka Pharmaceutical Co., Ltd.
Ischemia, Cerebral, Ischemic Stroke
Detection of Cerebral Ischemia With Artificial Intelligence.
In patients undergoing planned surgery for carotid tromendarterendectomy, a non-invasive device that registers heart rate variability is attached.
- Conditions
- Ischemia, Cerebral, Ischemic Stroke, Artery Occlusion, Artery Carotid Stenosi
- Trial name
- CIDAI-BAS (NCT03919370)
- Testing
- No intervention
- Where
- Sweden
- Volunteers
- 60 people
- Sponsor
- Linda Block
Acute Myocardial Infarction, Severe Periodontitis
Impact of Treating Severe Periodontitis on Inflammatory Activity of Atheromatous Plaques in Patients With Acute Myocardial Infarction (AMI)
Multicenter randomized clinical trial with two arms in patients hospitalized for an AMI nested in the Frenchie registry. Periodontal therapy is performed by periodontists in the intervention group versus treatment by dental…
- Conditions
- Acute Myocardial Infarction, Severe Periodontitis, Carotid Atherosclerosis
- Trial name
- PAROCARD (NCT04046237)
- Testing
- Periodontal treatment
- Where
- France
- Volunteers
- 210 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Hidradenitis, Hidradenitis Suppurativa
HIDRAdenitis Suppurativa and HEART Disease
In a prospective observational cohort study (n = 250) the investigators aim to assess the correlation between cardiac biomarkers, advanced echocardiography and HS severity and determine whether these are prognostic markers of…
- Conditions
- Hidradenitis, Hidradenitis Suppurativa, Hidradenitis Suppurativa, Familial, Left Ventricular Dysfunction
- Trial name
- NCT05989945
- Where
- Denmark
- Volunteers
- 250 people
- Sponsor
- Herlev and Gentofte Hospital
Cardiovascular Diseases, Stroke
Prediction of Primary Cardiovascular Events Using the Multimarker Approach
The study of biochemical risk factors for cardiovascular diseases is important not only for analysis, but also for preventive measures, given that changes in the level of biomarkers can be detected before the first clinical…
- Conditions
- Cardiovascular Diseases, Stroke, Myocardial Infarction, Death
- Trial name
- NCT05704569
- Testing
- measurement of multiple biomarkers
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Karaganda Medical University
Acute Coronary Syndrome or B Cerebral Infarction Requiring DAPT(Clopidogrel + Aspirin) for at Least 6 Months
An Observational Study to Evaluate the Incidence of MACCE According to Time Interval of Taking Medication in Patients With Acute Coronary Syndrome or Cerebral Infarction Who Received DAPT for the Secondary Prevention and Esomezol Cap for the Prevention of Gastrointestinal Bleeding
This study is to evaluate the incidence rate of Major Adverse CardioCerebrovascular Events(MACCE) in Patients with Acute Coronary Syndrome or Cerebral Infarction Who Received DAPT for the secondary prevention and Esomezol Cap for…
- Trial name
- NCT05487560
- Testing
- Esomezol Cap
- Where
- South Korea
- Volunteers
- 4,133 people
- Sponsor
- Hanmi Pharmaceutical Company Limited
Silent Stroke, Silent Cerebral Infarct
Prevalence of Attributable Etiology and Modifiable Stroke Risk Factors in Patients With Covert Brain Infarctions
The CBI registry is a prospective, interdisciplinary, multimodal observational registry of patients with covert brain infarction.
- Conditions
- Silent Stroke, Silent Cerebral Infarct, Covert Brain Infarct, Covert Brain Infarction
- Trial name
- CBI-Registry (NCT05685069)
- Where
- 2 sites in France, Switzerland
- Volunteers
- 230 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Acute Ischemic Stroke
Comparing Between CO2 and Phenylephrine Treatment in Patients With Progressive Lacunar Infarction (CARBOGEN Study)
Lacunar infarction is an ischemic stroke occurred by small perforating artery occlusion . Twenty percent of ischemic stroke is lacunar infarction.
- Trial name
- NCT04839224
- Testing
- carbogen, phenylephrine
- Where
- South Korea
- Volunteers
- 3 people
- Sponsor
- Yonsei University
Aortic Valve Disease, Myocardial Infarction
Aspirin Versus Aspirin+Clopidogrel as Antithrombotic Treatment Following TAVI
The purpose of this study is to compare aspirin/acetylsalicylic acid+ clopidogrel with aspirin/acetylsalicylic acid alone as antithrombotic treatment following TAVI for the prevention of major ischemic events (MI, ischemic…
- Conditions
- Aortic Valve Disease, Myocardial Infarction, Stroke, Bleeding
- Trial name
- ARTE (NCT02640794)
- Testing
- Clopidogrel, Aspirin
- Where
- 4 sites in Canada, Chile and 1 more
- Volunteers
- 222 people
- Sponsor
- Centre de Recherche de l'Institut Universitaire de Cardiologie et de Pneumologie de Quebec
Heart Attack and Stroke
Emergency Call for Heart Attack and Stroke (ECHAS) - ECHAS One Study
ECHAS One will test the use of a smartphone app to assist patients to decide if it is necessary to call for emergency care with symptoms that could represent a heart attack or stroke.
- Trial name
- ECHAS (NCT05230069)
- Testing
- Interview
- Volunteers
- 200 people
- Sponsor
- Emergency Call for Heart Attack and Stroke (ECHAS)
Coronary Artery Disease, Chest Pain
Artificial Intelligence Stress Echo (FINESSE) Project
The goal of this observational study is to learn whether combining stress echocardiography (stress echo) results with routine clinical information can better predict important heart outcomes in adults (18+) with chest pain who…
- Conditions
- Coronary Artery Disease, Chest Pain, Myocardial Ischemia, Angina Pectoris
- Trial name
- FINESSE (NCT07432620)
- Testing
- Dobutamine Stress Echocardiography
- Where
- United Kingdom
- Volunteers
- 2,281 people
- Sponsor
- Milton Keynes University Hospital NHS Foundation Trust
Cerebral Infarction, Stroke
CHInese Medicine NeuroAid Efficacy on Stroke Recovery
CHIMES is a double blind, placebo controlled, randomized, multicenter study to test the hypothesis that NeuroAid is superior to placebo in reducing neurological deficit and improving functional outcome in patients with cerebral…
- Trial name
- CHIMES (NCT00554723)
- Testing
- NeuroAid
- Where
- 24 sites in Hong Kong, Malaysia and 4 more
- Volunteers
- 1,100 people
- Sponsor
- CHIMES Society
Acute Cerebral Ischemia, Endovascular Thrombectomy
The Impact of Age on Short-term Post-thrombectomy Outcomes in Patients Aged 70 or Beyond With Acute Ischemic Stroke
A recent Cochrane systematic review of 18 randomized controlled trials (RCTs) comparing endovascular intervention-either mechanical thrombectomy or intra-arterial thrombolysis combined with medical treatment-to conservative…
- Conditions
- Acute Cerebral Ischemia, Endovascular Thrombectomy, Prognosis, Age Factors
- Trial name
- NCT06953427
- Where
- Taiwan
- Volunteers
- 94 people
- Sponsor
- Kuang Tien General Hospital
Wallenberg Syndrome
Effect of Virtual Reality Therapy on Dysphagia in Wallenberg Syndrome
The goal of this clinical trial is to learn about on dysphagia in wallenberg syndrome. The main questions it aims to answer are: the efficacy of Virtual Reality Therapy in the rehabilitation of patients with dysphagia in…
- Trial name
- NCT06286020
- Testing
- Virtual Reality Therapy, Conventional dysphagia treatment
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- Zeng Changhao
Stroke, Cerebral Infarction
Transcranial Stimulation and Motor Training in Stroke Rehabilitation
This study aims to test whether repeated sessions of tDCS result in long-lasting improvements in motor function in patients with chronic stroke.
- Conditions
- Stroke, Cerebral Infarction, Cerebrovascular Disorders, Brain Diseases
- Trial name
- tDCS (NCT01414582)
- Testing
- Anodal tDCS, Motor Training
- Where
- United Kingdom
- Volunteers
- 80 people
- Sponsor
- University of Oxford
Atrial Fibrillation
Trial of Apixaban vs Warfarin in Reducing Rate of Cognitive Decline, Silent Cerebral Infarcts and Cerebral Microbleeds in Patients With Atrial Fibrillation
The investigators' central hypothesis is that in patients with atrial fibrillation, anticoagulation with Apixaban reduces the rate of decline in cognitive function, when compared to Warfarin.
- Trial name
- ARISTA (NCT03839355)
- Testing
- Apixaban, Warfarin
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Mayo Clinic
Stroke
Predicting Cognitive Development in Younger Stroke Patients Using the Oxford Cognitive Screen
The purpose of this study is to investigate whether Oxford Cognitive Screen (OCS) can be used as a predictive tool during hospital admission in younger (<65 years) stroke patients, i.e.
- Trial name
- STROKY (NCT05612815)
- Where
- Denmark
- Volunteers
- 90 people
- Sponsor
- Bispebjerg Hospital