Clinical trials: Induced Vaginal Delivery
Induction of Labor Affected Fetus / Newborn
An RCT of a Synthetic Osmotic Cervical Dilator for Induction of Labour in Comparison to Dinoprostone Vaginal insErt
Induction of labour (where labour is started artificially) is traditionally carried out with a range of different drugs or by surgery (rupturing the membranes or 'waters').
- Trial name
- SOLVE (NCT03001661)
- Testing
- Dilapan-S, Dinoprostone
- Where
- United Kingdom
- Volunteers
- 674 people, healthy volunteers welcome
- Sponsor
- Birmingham Women's NHS Foundation Trust
Induced Vaginal Delivery
Potential of Vojta's Reflex Locomotion as a Pre/Induction Method for Uterine Activity: a Pilot Study
The Vojta's method is neurophysiological rehabilitation method used to support and induce reflex responses of locomotor and vegetative system.
- Trial name
- NCT06339528
- Testing
- Vojta's Reflex Locomotion
- Where
- Czechia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Faculty Hospital Kralovske Vinohrady
Induced; Birth, Cervical Dilatation
Induction to Labour With Double Cervical Ballon at Home Versus at Hospital
The goal of this clinical trial] is to compare the outcomes between induction to labour at home versus hospitalized. The main questions it aims to answer are: Can the induction to labour at home with cervical rippening ballon…
- Conditions
- Induced; Birth, Cervical Dilatation, Live Birth
- Trial name
- INDOBAMHOS (NCT06053073)
- Testing
- Cervical rippening at home, Cervical rippening in the hospital
- Where
- Spain
- Volunteers
- 834 people, healthy volunteers welcome
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Bronchopulmonary Dysplasia
The Role of Volatile Organic Compounds (VOCs), Airway Mucins and the Microbiome in the Early Prediction of Bronchopulmonary Dysplasia (BPD)
Bronchopulmonary dysplasia (BPD), the most common respiratory complication of extremely preterm birth, significantly impacts healthcare with high morbidity and mortality rates.
- Trial name
- INFANCY (NCT06342752)
- Testing
- Breath test, Throat swabs, Placental samples
- Where
- Belgium
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University Hospital, Antwerp
Induced Vaginal Delivery
Newborn Pain and Stress Levels in Oxytocin Induction at Birth
The aim of the study is to compare pain and stress levels in the early neonatal period in newborns with and without oxytocin induction. The research was conducted in a case-control study design.
- Trial name
- NCT06474000
- Testing
- Oxytocin induction group, Control group
- Where
- Turkey (Türkiye)
- Volunteers
- 164 people, healthy volunteers welcome
- Sponsor
- Kocaeli University
Labour, Induced, Vaginal Birth After Caesarean
Membrane Sweeping Versus Transcervical Foley Catheter for Induction of Labour in Women With Previous Caesarean Delivery
Nowadays, more and more women embark on pregnancy with previous Caesarean scar. One in five pregnancies requires induction of labour.
- Trial name
- NCT03326557
- Testing
- Membrane Sweeping versus Transcervical Foley Catheter for Induction of Labour in Women with Previous Caesarean Delivery
- Where
- Malaysia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ministry of Health, Malaysia
Healthy
Ethylvinyl Acetate (EVA) Vaginal Ring Delivery System Study
This research study is looking at how well a new drug delivery system, called the vaginal ring, works to get hormones into your body as a form of birth control.
- Trial name
- VaginalRing (NCT00706784)
- Testing
- Ethylvinyl Acetate (EVA) Vaginal Ring Delivery System
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Labor, Induced, Induced; Birth
Effect of Acidic Vaginal pH on the Efficacy of Dinoprostone for Labor Induction
Acidification of vaginal pH has been proposed as a potential factor that could help increase the efficacy of vaginal prostaglandins in labor induction.
- Trial name
- NCT05100264
- Testing
- Vaginal washing with 5% acetic acid, Vaginal washing with 0.9% NS
- Where
- Greece
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- Alexandra Hospital, Athens, Greece
Normal Vaginal Delivery
Oral Misoprostol Solution in Comparison to Vaginal Misoprostol in Induction of Labor
Induction of labour at term is a common obstetric intervention. Induction of labour is the artificial initiation of labour before its spontaneous onset for the purpose of delivery of the fetoplacental unit using mechanical or…
- Trial name
- NCT03863392
- Testing
- Misoprostol
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Vaginal Delivery, Labor
Labor Protocol Study
The goal of this study is to see if there is a better way to induce labor.
- Conditions
- Vaginal Delivery, Labor, Induced; Birth
- Trial name
- NCT04004845
- Testing
- Cytotec, oxytocin, Cervical Foley Balloon
- Where
- United States
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Induced Vaginal Delivery
IV PAPAVERINE Prior to Propess for Labor Induction
The investigators aim to evaluate the effect of administering papaverine prior to PGE2 insertion on changes in Bishop-scores and on the induction-to-delivery interval. Researchers will compare drug papaverine to a placebo
- Trial name
- NCT06550232
- Testing
- Papaverine
- Where
- Israel
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Western Galilee Hospital-Nahariya
Labor Pain
Failure of Vaginal Delivery After Induction
The study will compare the number of women who deliver vaginally after artificial initiation of labor pains(i.e. induction of labor) by two methods.
- Trial name
- NCT02758340
- Testing
- Misoprostol, foley's balloon catheter
- Where
- Pakistan
- Volunteers
- 335 people, healthy volunteers welcome
- Sponsor
- Karachi Medical and Dental College
Induced Vaginal Delivery
Comparing Foley Catheter Balloon With Early Amniotomy for Induction of Labor at Term
This study evaluates the intervention for induction of labor with low bishop scores . One group will be induced by transcervical Foley catheter balloon and vaginal PGE2 and other group will be induced by early amniotomy and PGE2…
- Trial name
- NCT03629548
- Testing
- early amniotomy, foley catheter balloon placement
- Where
- Turkey (Türkiye)
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Zeynep Kamil Maternity and Pediatric Research and Training Hospital
Intrauterine Fetal Demise, Fetal Death
Mifepristone Induction for Fetal Demise
Methods: Double blinded, randomized controlled trial with 1:1 allocation of mifepristone or placebo at initiation of induction of labor for fetal demise 20 weeks estimated gestational age or greater.
- Trial name
- MIFD (NCT02620904)
- Testing
- Mifepristone
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Threatened Abortion, Pre-Eclampsia
Progesterone for First Trimester Vaginal Bleeding
The purpose of this study is to investigate whether treatment with progesterone for patients with first trimester vaginal bleeding will alter the rates of obstetrical complications and adverse pregnancy outcomes.
- Conditions
- Threatened Abortion, Pre-Eclampsia, Abruptio Placentae, Fetal Growth Retardation
- Trial name
- NCT01501890
- Testing
- dihydroxyprogesterone caproate
- Where
- Israel
- Volunteers
- healthy volunteers welcome
- Sponsor
- Soroka University Medical Center
Induced Vaginal Delivery
Cervical Gland Area as a Predictor of Success of Labour Induction
Women who fulfil the inclusion criteria and who are planned for labour induction will be recruited. Bishop score, cervical length, and the presence of cervical glandular area (CGA) will be documented for every patient up to 12…
- Trial name
- NCT04416022
- Testing
- Ultrasound examination
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Trial of Labor After Cesarean, Vaginal Birth After Cesarean
Balloon Catheter Combined With Oxytocin Induction Among the Pregnant Women With Previous Cesarean Section
This study is a multi-center, prospective, observational clinical trial study. 924 full-term pregnant women will be enrolled as subjects, and the ratio of eligible subjects in the two groups is 1:1.
- Conditions
- Trial of Labor After Cesarean, Vaginal Birth After Cesarean, Bishop Score, Failed Mechanical Induction
- Trial name
- NCT05246761
- Testing
- Balloon catheter
- Where
- China
- Volunteers
- 924 people, healthy volunteers welcome
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Labor Induction, Induced Delivery
Foley Catheter Versus PGE2 for Labor Induction at Term: a Pilot Study
Induction of labor is one of the most common interventions in obstetrics. In the past decade, the rates of labor induction at term have doubled from approximately 9% to 23% in the United States and from 10% to 20.4% in China.
- Trial name
- NCT04780269
- Testing
- Induction of labor with Foley catheter, Induction of labor with PGE2
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Guangzhou Women and Children's Medical Center
Induced Vaginal Delivery, Induced; Birth
Outpatient Transcervical Balloon For Induction of Labor
The goal of this randomized control trial is to compare outpatient transcervical foley balloon to inpatient vaginal misoprostol in pregnant women for cervical ripening. The main questions it aims to answer are: 1.
- Trial name
- NCT05798728
- Testing
- Outpatient transcervical foley balloon, Inpatient Vaginal Misoprostol
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Hurley Medical Center
Obesity, Labor Induction
Cervical Ripening for Obese Women: A Randomized, Comparative Effectiveness Trial
Obese pregnant women (BMI ≥ 30 kg/m2) are more likely than their normal-weight counterparts to require induction of labor because of increased rates of obstetric complications including pregnancy related hypertensive disorders…
- Conditions
- Obesity, Labor Induction, Cesarean Delivery
- Trial name
- CROWN (NCT02639429)
- Testing
- Vaginal Misoprostol, Foley Balloon + Vaginal Misoprostol
- Where
- United States
- Volunteers
- 236 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston