Clinical trials: Individuality
Differential Female Response to Δ9-tetrahydrocannabinol (THC)
Individual Differences in Drug Response
Females are increasingly using cannabis, yet remain underrepresented in preclinical and clinical cannabinoid research. This female-specific research plan will test the effects of two recreationally relevant doses of oral THC and…
- Trial name
- IDT (NCT03809546)
- Testing
- Dronabinol, dextrose
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Pain, Acute
Brain and Genetic Predictors of Individual Differences in Pain and Analgesia
The purpose of the study is to gain a better understanding of pain processing in the brain. Our understanding of how pain is processed in the brain is limited.
- Trial name
- PAINGEN (NCT03781570)
- Testing
- Control Cream
- Where
- United States
- Volunteers
- 541 people, healthy volunteers welcome
- Sponsor
- Trustees of Dartmouth College
Surgery, Individuality
The Realtime Detection for Individual Variation of Analgesic ：A Comparison of Sufentanil vs Fentanyl
Purpose: This study aimed to find a quick and timely way to investigate the individual variation of efficacy of opioid analgesic in Chinese patients undergoing elective surgeries.
- Trial name
- NCT01748071
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Huazhong University of Science and Technology
Autism Spectrum Disorders
Gaming for Autism to Mold Executive Skills Project
The goal of the project is to better understand executive control-how children manage complex or conflicting information in the service of a goal.
- Trial name
- GAMES (NCT02361762)
- Testing
- Computerized executive control training
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Boston Children's Hospital
Individuality
Study of Glasgow Coma Scale in Neurological Patients
The assessment of the level of consciousness in patients admitted to intensive care units (ICU) can be complicated because the variables that are evaluated can be interpreted in a different way by different observers.
- Trial name
- NCT01641978
- Where
- Spain
- Volunteers
- 125 people
- Sponsor
- Hospital Universitario Getafe
Opioid Sensitivity, Individual Difference
A118G SNP and OPRM1 Gene Opioid-Mediated Effects in Humans
Within-subject, double-blind, placebo-controlled examination of opioid abuse potential in healthy individuals as a function of A118G SNP on the OPRM1 gene.
- Conditions
- Opioid Sensitivity, Individual Difference, Abuse Opioids
- Trial name
- NCT02360371
- Testing
- Within-subject test of blinded study medication
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Healthy
Individual Differences in the Response to Drugs
The purpose of this study is to examine whether individual differences in acute responses to drugs co-vary across three drugs from different drug classes: alcohol, amphetamine and delta-9-tetrahydrocannabinol (THC).
- Trial name
- TDS (NCT02485158)
- Testing
- THC, AMP, ALC
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Smoking Addiction
Effectiveness of Varenicline: Testing Individual Differences
The study will evaluate the effectiveness of smoking cessation using Varenicline versus placebo. Effectiveness will be measured by the average number of cigarettes smoked per smoking day for up to 36 weeks.
- Trial name
- Varenicline (NCT01228175)
- Testing
- Varenicline
- Where
- United States
- Volunteers
- 218 people
- Sponsor
- The Mind Research Network