Clinical trials: Incontinence
Overactive Bladder
SSR240600C Treatment in Women With Overactive Bladder
The primary objective of this study is to evaluate the efficacy of SSR240600C in women with overactive bladder compared to placebo using tolterodine as a study calibrator.
- Trial name
- BILADY (NCT00564226)
- Testing
- SSR240600C, tolterodine
- Where
- 7 sites in United States, Canada and 5 more
- Volunteers
- 345 people
- Sponsor
- Sanofi
Stress Urinary Incontinence
A Post-Market Study of the AMS AdVance™ Male Sling System for the Treatment of Male Stress Urinary Incontinence
A prospective, multi-center study of the AdVance Male Sling for Stress Urinary Incontinence. The purpose of this study is to obtain surgical technique data for use in physician education and training and to collect early clinical…
- Trial name
- NCT00998790
- Testing
- American Medical Systems (AMS) AdVance™ Male Sling System
- Where
- 3 sites in Belgium, France
- Volunteers
- 114 people
- Sponsor
- Boston Scientific Corporation
Benign Prostatic Hyperplasia
Preoperative Anxiety and Surgical Fear in Holmium Laser Enucleation of the Prostate and Transurethral Resection of the Prostate Patients With Benign Prostatic Hyperplasia
Benign prostatic hyperplasia (BPH) is a common condition in older men and may cause bothersome lower urinary tract symptoms that can negatively affect quality of life.
- Trial name
- HoLEP and TURP (NCT07663097)
- Testing
- Holmium Laser Enucleation of the Prostate (HoLEP), Transurethral Resection of the Prostate (TURP)
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people
- Sponsor
- Hitit University
Urinary Incontinence
Urinary Incontinence and Transtheoretical Model
The aim of the study is to evaluate the effectiveness of nursing care given online to women with urinary incontinence based on the Transtheoretical (Change) Model.
- Trial name
- NCT04688047
- Testing
- Nursing care based on the transtheoretical model
- Where
- Turkey (Türkiye)
- Volunteers
- 59 people
- Sponsor
- Kutahya Health Sciences University
Urinary Incontinence, Obesity
BUDI (Bariatric UroDynamic Improvement)
In the population of obese women, the prevalence of urinary incontinence (UI) is around 70%. It was shown in the literature that weight loss by bariatric surgery allowed a significant improvement in the symptoms and impact on the…
- Conditions
- Urinary Incontinence, Obesity, Urodynamics, Quality of Life
- Trial name
- BUDI (NCT03509038)
- Testing
- Exploratory pathophysiology Study
- Where
- France
- Volunteers
- 25 people
- Sponsor
- University Hospital, Caen
Urinary Incontinence
Clinically Important or Just Statistically Significant? MCID for DVISS and PIN-Q in Children With UI
The goal of this study was to determine the Minimal Clinically Important Difference (MCID) for the Dysfunctional Voiding and Incontinence Symptom Score (DVISS) and the Pediatric Incontinence Questionnaire (PIN-Q) in children with…
- Trial name
- NCT07242898
- Testing
- Standard Urotherapy (SU)
- Volunteers
- 100 people
- Sponsor
- Artvin Coruh University
Urinary Incontinence
Predictors of Delay in Treatment of Urinary Incontinence
246 women were selected as participants to fill and submit the Study Proforma among 264 incontinent women. The Performa included demographic features of the subjects, their chronic ailments, psychosocial effects, reasons for the…
- Trial name
- Predictors (NCT04470700)
- Where
- Pakistan
- Volunteers
- 298 people
- Sponsor
- Shazia Saaqib
Healthy Subjects, Overactive Bladder
Evaluate the Safety, Tolerability and PK of Different Formulations of Orally Administered Solabegron in Healthy Male Subjects
The purpose of this study is to evaluate the safety, tolerability and pharmacokinetics of different formulations of orally administered solabegron in healthy male subjects.
- Trial name
- NCT02938507
- Testing
- Formulation 1 solabegron, Formulation 2 solabegron
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Velicept Therapeutics, Inc.
Urinary Incontinence, Stroke, Complication
Effectiveness and Safety of Electroacupuncture on Poststroke Urinary Incontinence
This pilot protocol is aimed to evaluate the effectiveness and safety of electroacupuncture therapy for the post-stroke patients with urinary incontinence.
- Trial name
- NCT02819336
- Testing
- Electroacupuncture (EA)
- Where
- 2 sites in South Korea
- Volunteers
- 56 people
- Sponsor
- Kyunghee University
Fecal Incontinence
Percutaneous Tibial Nerve Stimulation in the Treatment of Fecal Incontinence
Background of the study: Fecal incontinence is a complex problem. The social consequences of this problem result in a lower quality of life. The exact prevalence of FI is unknown, literature reports vary from 13-19%.
- Trial name
- NCT00974909
- Testing
- Urgent PC neuromodulation system
- Where
- 3 sites in France, Italy and 1 more
- Volunteers
- 59 people
- Sponsor
- Maastricht University Medical Center
Urinary Bladder, Overactive
Efficacy and Safety of GSK1358820 in Subjects With Overactive Bladder
GSK1358820 is a botulinum neurotoxin A complex that has been approved for the treatment of overactive bladder (OAB) in several countries, however, it has not been approved for OAB treatment in Japan.
- Trial name
- NCT02820844
- Testing
- GSK1358820, Antibiotic therapy, Bladder diary
- Where
- 48 sites in Japan
- Volunteers
- 250 people
- Sponsor
- GlaxoSmithKline
Urinary Incontinence,Stress
Female Sling Procedure
In trans-obturator tape (TOT), tension and location of the tape in mid urethral zone are directly related to the postoperative clinical outcome.
- Trial name
- NCT04571346
- Testing
- trans-obturator procedure
- Volunteers
- 100 people
- Sponsor
- Ain Shams University
Vaginal Dryness, Breast Cancer
Vaginal DHEA for Women After Breast Cancer
There does not appear to be a consensus regarding the treatment of vaginal dryness in women who have a contraindication to the use of estrogen products.
- Conditions
- Vaginal Dryness, Breast Cancer, Urinary Incontinence, Quality of Life
- Trial name
- NCT01724242
- Testing
- Vaginal DHEA
- Where
- Israel
- Sponsor
- Hadassah Medical Organization
Stress Urinary Incontinence
Urodynamic Study and Stress Incontinence
A trial to answer the debatabal question about the role of urodynamic study in surgical treatment for stress urinary incontinence.
- Trial name
- NCT03300973
- Testing
- sling surgery
- Where
- Egypt
- Volunteers
- 125 people
- Sponsor
- Kasr El Aini Hospital
Idiopathic Overactive Bladder With Urinary Incontinence
Safety and Tolerability of TAR-302-5018 in Subjects With Idiopathic Overactive Bladder
The purpose of this study is to determine if TAR-302-5018, an investigational drug-delivery system, is safe and tolerable in patients with idiopathic overactive bladder and urinary incontinence.
- Trial name
- NCT03109379
- Testing
- Trospium-Releasing Intravesical System (TAR-302-5018)
- Where
- 12 sites in United States
- Volunteers
- 43 people
- Sponsor
- Taris Biomedical LLC
Fecal Incontinence, Anal Incontinence
Medical and Economic Evaluation of a Magnetic Anal Sphincter for Patients With Severe Anal Incontinence
The purpose of this study is to compare 2 surgical treatments of severe fecal incontinence (defined as more than a major leak per week).
- Trial name
- MOS STIC (NCT01920607)
- Testing
- magnetic anal sphincter, sacral nerve stimulation
- Where
- France
- Volunteers
- 71 people
- Sponsor
- Nantes University Hospital
Urge Incontinence
Trial of Continuous Versus Cyclic Stimulation in Interstim Therapy
Sacral Nerve Stimulation (SNS) delivers non-painful, mild electrical pulses to the sacral nerves to modulate the reflexes that influence the bladder, sphincter, and pelvic floor to improve or restore normal voiding function.
- Trial name
- NCT00928499
- Testing
- Interstim (SNS)
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- University of California, Irvine
Urinary Incontinence, Sarcopenia
The Urinary Incontinence Treatment Study
Investigators plan a prospective cohort study with an adaptive design based on physical function status. The design will involve tracking the number of women recruited with physical function impairment and those without any…
- Trial name
- UNITS (NCT03057834)
- Testing
- Pelvic floor muscle exercise
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Fecal Incontinence
Safety and Efficacy of Anorectal Application of Dx-gel for Treatment of Anal Incontinence
The purpose of this study is to determine whether anorectal application of Nasha Dx is safe and effective for treatment of anal incontinence.
- Trial name
- NCT01380132
- Testing
- Anal injection of Nasha Dx
- Where
- Sweden
- Volunteers
- 35 people
- Sponsor
- Uppsala University Hospital
Electric Stimulation Therapy, Bowel Dysfunction
The Effect of NMES on Bowel Management in People With Chronic SCI
It has been reported that 62% of all people with Spinal Cord Injury (SCI) have experienced faecal incontinence and that neurogenic bowel dysfunction (NBD) is a major sequela.
- Conditions
- Electric Stimulation Therapy, Bowel Dysfunction, Spinal Cord Injuries, Defecation Disorder
- Trial name
- FES_Bowel (NCT04914975)
- Testing
- Neuromuscular electrical stimulation
- Where
- Switzerland
- Volunteers
- 20 people
- Sponsor
- Swiss Paraplegic Research, Nottwil