Clinical trials: Incomplete Spinal Cord Injury
Spinal Cord Injuries
Robotic Gait Training in Spinal Cord Injury
INTRODUCTION: The ability to move and transfer own body in an effective manner, is frequently affected in people with a spinal cord injury with a negative impact in mood and quality of life, in such a way, that achieving an…
- Trial name
- NCT02749357
- Testing
- 30 minutes Lokomat, 60 minutes Lokomat
- Where
- Mexico
- Volunteers
- 44 people
- Sponsor
- Instituto Nacional de Rehabilitacion
Incomplete Spinal Cord Injury
Device-induced Intermittent Hypoxia in Persons With Incomplete Spinal Cord Injury
Spinal cord injury (SCI) is a devastating disability with physical, social and vocational consequences. Owing to its overwhelming complications, the cost of treatment and rehabilitation increases constantly.
- Trial name
- NCT05491837
- Testing
- Device induce acute intermittent hypoxia 9 % of Oxygen, Normoxia 21% of oxygen
- Where
- Pakistan
- Volunteers
- 68 people
- Sponsor
- Riphah International University
Spinal Cord Injuries
rTMS and Body Weight-support Treadmill Training After Incomplete Spinal Cord Injury
The aim of this study is to verify the efficacy of body weight-support treadmill training combined with high-frequency rTMS in improving the sensory-motor function of adult patients with chronic incomplete thoracolumbar spinal…
- Trial name
- NCT03394560
- Testing
- High frequency repetitive transcranial magnetic stimulation
- Where
- Brazil
- Volunteers
- 20 people
- Sponsor
- Universidade Federal de Pernambuco
Degenerative Disc Disease, Trauma (Including Fractures)
BIO4 Clinical Case Study: Cervical Spine
The goal of this study is to investigate the efficacy of BIO4 bone matrix in patients undergoing 1 or 2-level Anterior Cervical Discectomy and Fusion (ACDF) spine surgery.
- Conditions
- Degenerative Disc Disease, Trauma (Including Fractures), Spondylolisthesis
- Trial name
- NCT03077204
- Testing
- 1 or 2-Level ACDF utilizing BIO4 with Bio AVS Cervical Allograft (with graft window)., Aviator Anterior Cervical Plating System
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Seton Healthcare Family
Spinal Cord Injury
Effects of Lokomat Training on Dynamic Postural Stability in Incomplete Spinal Cord Injury
The study aims to evaluate the effects of robotic-assisted gait training (Lokomat) on dynamic postural stability in patients with incomplete spinal cord injury (SCI).
- Trial name
- NCT07621900
- Testing
- Robotic Rehabilitation, Control
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- I.R.C.C.S. Fondazione Santa Lucia
Stroke, Incomplete Spinal Cord Injury
Comparison of Gait Training Methods in Sub-acute Stroke and Spinal Cord Injury
The purpose of the project is to compare intensity (minutes in target heart rate zone) and steps per session across three gait training modalities, including body-weight supported treadmill training (BWSTT), overground gait…
- Trial name
- NCT06169657
- Testing
- Body-weight-supported treadmill training (BWSTT), EksoNR exoskeleton gait training, Overground gait training
- Where
- United States
- Sponsor
- Shirley Ryan AbilityLab
Spinal Cord Injury
Restoring Walking With a Powered Exoskeleton After Spinal Cord Injury
Powered exoskeletons have emerged recently, promising to offer walking to individuals with severe spinal cord injury who are unable to walk.
- Trial name
- NCT02322125
- Testing
- ReWalk
- Where
- Canada
- Volunteers
- 12 people
- Sponsor
- University of Alberta
Incomplete Spinal Cord Injury
Amplify Gait to Improve Locomotor Engagement in Spinal Cord Injury
Spinal cord injury (SCI) affects ~42,000 Veterans. The VA provides the single largest network of SCI care in the nation. The lifetime financial burden of SCI can exceed $3 million. A major cost of SCI is impaired mobility.
- Trial name
- AGILE SCI (NCT04340063)
- Testing
- Gait training performed on a treadmill, Gait training performed in a Movement Amplification Environment
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- VA Office of Research and Development
Spinal Cord Injuries, Muscle Pareses
A Novel Combined Neuromodulation Therapy to Enhance Balance and Neuroplasticity
Many people with partial damages in their spinal cord (iSCI) have physical impairments such as muscle paralysis in legs which make standing balance difficult.
- Conditions
- Spinal Cord Injuries, Muscle Pareses, Fall
- Trial name
- NCT05940636
- Testing
- Activity-based rehabilitation+electrical stimulation
- Where
- Canada
- Volunteers
- 17 people
- Sponsor
- University Health Network, Toronto
Spinal Cord Injuries
Investigation Into an Innovative, Clinical Slip Inducing Device in the Chronic Incomplete Spinal Cord Population
The objective of this project is to fully test a newly developed affordable cost variable slip inducer in the ambulatory, incomplete spinal cord population.
- Trial name
- NCT03744286
- Testing
- Slip Training
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Shirley Ryan AbilityLab
Incomplete Spinal Cord Injury
Effects of Transcutaneous Spinal Direct Current Stimulation in Incomplete Spinal Cord Injury
The purpose of the study is to investigate the effects of a novel therapeutic approach with transcutaneous spinal direct current stimulation (tsDCS) to promote functional recovery and spasticity in chronic spinal cord injury…
- Trial name
- NCT03249454
- Testing
- Anodal tsDCS, Cathodal tsDCS
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- The University of Texas Health Science Center, Houston
Spinal Cord Injuries
Aquatic Specific Physiotherapy on Incomplete Spinal Cord Injuries
Purpose of the study: To analyse the effectiveness of aquatic physiotherapy on spinal cord injuries (LMi) in the improvement of balance and gait, in the inflammatory profile, and the impact on the quality of life.
- Trial name
- FALMI (NCT03962218)
- Testing
- aquatic physiotherapy
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- University of Castilla-La Mancha
Spinal Cord Injuries, Spinal Cord Diseases
PAS for Lower Extremity Rehabilitation in Tetraplegic Patients
The investigators have recently shown in incomplete SCI patients that long-term paired associative stimulation is capable of restoring voluntary control over some paralyzed muscles and enhancing motor output in the weak muscles…
- Trial name
- NCT03459885
- Testing
- Paired associative stimulation (with eXimia magnetic stimulator and Dantec Keypoint® electroneuromyography device)
- Where
- Finland
- Volunteers
- 5 people
- Sponsor
- Helsinki University Central Hospital
Spinal Cord Injury
Robotic-assisted Locomotor Training on Mobility and Cardiopulmonary Function in Patients Suffering From Spinal Cord Injury
Evidences showed that patients suffering from spinal cord injury (SCI) have poor mobility and higher chance to develop cardiopulmonary diseases, which leads to poor quality of life and shorter life expectancy.
- Trial name
- NCT01989806
- Testing
- Robotic-assisted body weight supported treadmill training (Lokomat V6, Hocoma AG, Switzerland), Passive lower limbs mobilization training (Motomed Vivo 2, RECK, Germany)
- Where
- China
- Volunteers
- 16 people
- Sponsor
- Kowloon Hospital, Hong Kong
Spinal Cord Injury
Rehabilitation Program for Bladder Control in Individuals With Incomplete Spinal Cord Injury
This prospective, randomized, double-blind clinical trial (with both participants and outcome assessors blinded to group assignments) was carried out at the outpatient clinic of the Faculty of Physical Therapy, Cairo University…
- Trial name
- BCSCI (NCT07008157)
- Testing
- 1. IFC, 2. Timed voiding., motor imagery training
- Where
- Egypt
- Volunteers
- 74 people
- Sponsor
- Cairo University
Secondary Osteoporosis, Spinal Cord Injury
The Efficacy of Denosumab in Incomplete Patients Spinal Cord Injury
The purpose of this study is to determine the usefulness of a drug, denosumab, to prevent the loss of bone in participants legs due to SCI.
- Trial name
- NCT03029442
- Testing
- Denosumab (Prolia)
- Where
- 2 sites in United States
- Volunteers
- 5 people
- Sponsor
- James J. Peters Veterans Affairs Medical Center
Spinal Cord Injuries
Technology-assisted Upper Extremity Rehabilitation in Subjects with Incomplete Cervical Spinal Cord Injury
The aim of the study is to investigate the effects of 6 weeks of technological-assisted rehabilitation on function of upper extremity and hand in subjects with incomplete cervical spinal cord injury.
- Trial name
- T-ARSCI (NCT04760470)
- Testing
- Technology-assisted upper extremity rehabilitation
- Where
- Finland
- Volunteers
- 20 people
- Sponsor
- University of Helsinki
Spinal Cord Injuries
Effects of Robotic Versus Manually-Assisted Locomotor Training for Individuals With Incomplete Spinal Cord Injury
The purpose of this study is to collect data comparing two means of providing locomotor training: manual and robotic and the possible differential effects it may have on walking ability for persons with spinal cord injury (SCI).
- Trial name
- DE (NCT00127439)
- Testing
- Manually Assisted Locomotor Training, Robotic Assisted Locomotor Training
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- VA Office of Research and Development
Severe Mobility Impairment, Spinal Cord Injuries (Complete and Incomplete)
The Impact of 'Digital Strolling' on Depression and Quality of Life of People With Severe Mobility Impairment
This intervention aims to develop and test the feasibility, acceptability, and preliminary effects of a "Digital Strolling" intervention among people with SMI.
- Conditions
- Severe Mobility Impairment, Spinal Cord Injuries (Complete and Incomplete), Poliomyelitis
- Trial name
- NCT07073144
- Testing
- Virtual walking, Passive observing walking
- Where
- Hong Kong
- Volunteers
- 24 people
- Sponsor
- The Hong Kong Polytechnic University
Psychological Well-Being, Spinal Cord Injuries
Self-Management Program for AIS D SCI
About 25-51% of adults with acquired spinal cord injury (SCI) have "AIS D" SCI, the lowest severity grade of neurologic injury. Veterans with AIS D SCI generally have better outcomes in mobility, community integration, and…
- Trial name
- SCISM-D (NCT05800717)
- Testing
- SCI Self-Management for AIS D
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- VA Office of Research and Development