Clinical trials: Incision Infection
Surgical Site Infections, Lumbar Disc Herniation
The Effect of Number of Showers With 4% Chlorhexidine Gluconate on Prevention of Surgical Site Infections
Surgical site infections (SSIs) are the most common type of nosocomial infection in surgical departments. Although lumbar disc herniation (LDH), which is one of the common cases in neurosurgery, is a serious problem affecting…
- Trial name
- SSI (NCT06801275)
- Testing
- 1 shower with 4% chlorhexidine gluconate, 2 shower with 4% chlorhexidine gluconate
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Çanakkale Onsekiz Mart University
Surgical Wound Infection, Cesarean Wound; Dehiscence
Sucrose as a Standard in Cesarean Section Surgical Wound Healing to Reduce Hospital Time
It is a randomized, single-blind clinical trial, whose population to be studied will be randomized patients with a diagnosis of dehiscence and infection of a cesarean surgical wound who meet the inclusion and exclusion criteria.
- Trial name
- SAGRA (NCT06477770)
- Testing
- Clorhexidine soap, Sucrose
- Where
- Honduras
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Universidad Nacional Autonoma de Honduras
Surgical Site Infection
Local Subcutaneous Gentamicin for Prevention of Surgical Site Infection After Elective Cesarean Section
The goal of this clinical trial is to evaluate whether local subcutaneous administration of gentamicin reduces the incidence of surgical site infection (SSI) following elective cesarean section.
- Trial name
- NCT07311395
- Testing
- Gentamicin, Standard antibiotic prophylaxis
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Western Galilee Hospital-Nahariya
Obesity, Morbid, Obesity
CiNPT for Abdominoplasties in Post-bariatric Patients Study
The overarching goal of this research is to assess whether the post-operative use of closed-incision Negative Pressure Therapy (ciNPT) accelerates healing of surgical wounds, improves surgical outcomes, and reduces the rate of…
- Conditions
- Obesity, Morbid, Obesity, Obesity, Abdominal, Wound
- Trial name
- CAPS (NCT04214236)
- Testing
- ciNPT group, Control group
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliera, Ospedale Civile di Legnano
Surgical Site Infection, Antibiotic Prophylaxis
The Role of Guideline-adherent Perioperative Antibiotic Administration and the Risk of Surgical Site Infections After Non-cardiac Surgery.
This study will seek to describe current practice of antibiotic prophylaxis to identify the effect of appropriate perioperative antimicrobial coverage - specifically regarding timing, dose adjustments, and redosing - on surgical…
- Trial name
- NCT03982810
- Testing
- Antibiotics
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Yale University
Surgical Site Infection
Antibiotics for Prevention of SSI in Obese Women Undergoing CS
Effect of cephalexin plus metronidazole on SSI better than cephalexin alone in obese women undergoing CS
- Trial name
- NCT03736187
- Testing
- Cephalexin
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Abscess, Pain
IN Ketamine Vs IN Midazolam and Fentanyl for Abscess I&D
The general objective of this study is to determine whether intranasal ketamine should be incorporated into formulary as an option to treat pain during minor procedures in the pediatric emergency department.
- Trial name
- NCT02635282
- Testing
- intranasal ketamine, intranasal fentanyl, intranasal midazolam
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of Tennessee
Surgical Site Infection, Surgical Wound Infection
Addition of Pre-wound Closure Povidone Iodine Wash Versus Direct Wound Closure Effect on Surgical Site Infections
A Randomized controlled trail to To assess the efficacy of povidone-iodine wash before wound closure in preventing surgical site infections.
- Trial name
- NCT05077592
- Testing
- 10% Povidone Iodine
- Where
- Egypt
- Volunteers
- 760 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Acute Appendicitis
The Comparison of Single Incision Laparoscopic Appendectomy and Three Port Laparoscopic Appendectomy
Laparoscopic techniques have allowed surgeons to perform complicated intrabdominal surgery with minimal trauma. In numerous studies, when conventional laparoscopic appendectomy using 3 ports is compared with open appendectomy, it…
- Trial name
- NCT01816568
- Testing
- SILS appendectomy, Three port laparoscopic appendectomy
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Maltepe University
Cesarean Section; Infection
Evaluation of Triclosan Coated Suture in Obstetrical Surgery
A prospective comparative randomized blinded study conducted in the obstetrics gynecology department of Ben Arous hospital over an eight-month period between November 2020 and June 2021.
- Trial name
- NCT05330650
- Testing
- Coated Vicryl+, Vicryl
- Where
- Tunisia
- Volunteers
- 318 people, healthy volunteers welcome
- Sponsor
- Tunis University
to See Whether Negative Pressure Wound Therapy Decreases Wound Infections.
Negative Pressure Wound Therapy - A Multi-Centered Randomized Control Trial
Children with neuromuscular disorders such as cerebral palsy, children with kyphosis and post-traumatic scoliosis have higher infection rates after scoliosis surgery than healthy children who undergo scoliosis surgery.
- Trial name
- NPWT (NCT02790385)
- Testing
- Negative Pressure Wound Therapy, Standard Gauze Treatment
- Where
- Canada
- Volunteers
- 870 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Antibiotic Side Effect, Eyelid; Wound
Topical Antibiotic Prophylaxis for Eyelids
The investigators propose a prospective randomized control trial testing the hypothesis that routine topical antibiotic prophylaxis does not significantly reduce the rate of infection after eyelid surgery.
- Conditions
- Antibiotic Side Effect, Eyelid; Wound, Eyelid Diseases, Surgical Wound Infection
- Trial name
- NCT03199911
- Testing
- Topical Antibiotic Product, Topical Non-Antibiotic Ointment
- Where
- United States
- Volunteers
- 401 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Surgical Site Infection
Chlorhexidine Cloths to Reduce Surgical Site Infection in Cesarean Deliveries
Pregnancy-associated infection represents a major cause of maternal morbidity and mortality. Cesarean delivery is the most common major surgical procedure and is associated with a rate of surgical site infection (SSI) that is…
- Trial name
- NCT04202471
- Testing
- Chlorhexidine Cloth
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Northwell Health
Hand Hygiene, Surgical Wound Infection
Surgical Handwashing: Drying With One or Two Surgical Towels
This study aims to determine whether the use of two sterile towels for drying after surgical handwashing results in fewer contamination events compared to the use of only one towel among healthcare personnel.
- Conditions
- Hand Hygiene, Surgical Wound Infection, Healthcare Associated Infection, Medical Errors
- Trial name
- NCT06420934
- Testing
- Drying procedure after surgical handwashing
- Where
- Colombia
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Instituto de Ortopedia Infantil Roosevelt
Infection
Analysis of the Incidence of Post-Operative Wound Infections After Spine Surgery
Post-operative wound infections can prolong hospital stays, increase rates of readmission to the intensive care unit, and increase the costs of treatment significantly.
- Trial name
- NCT02891486
- Testing
- Spinal surgery
- Where
- 2 sites in United States
- Volunteers
- 6,959 people, healthy volunteers welcome
- Sponsor
- University of Miami
Surgical Site Infection, Diabete Mellitus
Irrigation and Suction Trial to Prevent SSI
The study will be conducted on women with risk factors for SSI assigned to gynecological surgery with an open abdominal approach.
- Conditions
- Surgical Site Infection, Diabete Mellitus, Abdominal Hysterectomy
- Trial name
- I&S (NCT05611944)
- Testing
- Irrigation and suction through subcutaneus drains
- Where
- Pakistan
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- King Edward Medical University
Postoperative Wound Infection Deep Incisional Surgical Site, Prosthesis and Implants
Effect of Photodynamic Therapy on Skin Microbiome. Single Center Study (PHOMIC-II)
The overarching aim of this research project is to prevent orthopedic implant-associated infections. This study aims to investigate if PDT has an effect on bacterial skin colonization in order to improve skin antisepsis…
- Conditions
- Postoperative Wound Infection Deep Incisional Surgical Site, Prosthesis and Implants, Surgical Site Infection, Prosthetic Joint Infection
- Trial name
- NCT04618276
- Testing
- Photodynamic Therapy
- Where
- Switzerland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Surgical Site Infection, Surgical Complication
Oral Antibiotic Bowel Preparation in Gynecologic Oncology Surgery
The purpose of this study is to investigate whether the use of a preoperative antibiotic bowel regimen is associated with a reduced risk of deep organ/space surgical site infection in gynecologic oncology surgery.
- Conditions
- Surgical Site Infection, Surgical Complication, Gynecologic Cancer
- Trial name
- NCT05210556
- Testing
- Diagnosed with Surgical Site Infection
- Where
- United States
- Volunteers
- 778 people, healthy volunteers welcome
- Sponsor
- WellSpan Health
Edema, Pain
Comparison of Hyaluronidase and Dexametasone in Reduction of Postoperative Edema
The present study is designed to reveal effectiveness of hyaluronidase and dexamethasone on reduction of postoperative edema, pain, trismus, and infection.
- Conditions
- Edema, Pain, Trismus, Infection, Surgical Site
- Trial name
- NCT05466604
- Testing
- Hyaluronidase Injection mesomedica, Dexamethasone dekort
- Where
- 2 sites in Cyprus, Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Surgical Incision, Surgery--Complications
Zinc Oxide Versus Petrolatum Following Skin Surgery
Patients undergoing routine surgery in the Department of Dermatology for any indication on non-scalp skin and closed in linear fashion with scar greater than or equal to 4.5cm in length will be invited to participate in this…
- Conditions
- Surgical Incision, Surgery--Complications, Surgical Wound, Surgical Site Infection
- Trial name
- NCT03561376
- Testing
- Topical zinc oxide vs. petrolatum post-surgical scars
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Melissa Pugliano-Mauro