Clinical trials: Incision
Hemodynamic Instability
Scalp Block -Craniotomi
Postoperative pain after craniotomy is an important clinical problem as it can lead to hypertension and increased intracranial pressure.
- Trial name
- scalp block (NCT06264765)
- Testing
- scalp block, Incisional infiltration
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people
- Sponsor
- Aydin Adnan Menderes University
Wound Infection
Compare Antimicrobial to Conventional Suture in Patients Receiving Primary Total Knee Replacement
Total knee replacement is now one of the most popular reconstructive procedures for the elderly people to regain their functional capacity and life quality.
- Trial name
- Vicryl-Plus (NCT02533492)
- Testing
- vicryl, Vicryl plus
- Where
- Taiwan
- Volunteers
- 102 people
- Sponsor
- Mel Shiuann-Sheng Lee
Surgical Site Reaction
The Use of the Prevena Incision Management System (PIMS) on Closed Incisions in Renal Transplant Subjects
This study is being conducted to see how safe and effective the Prevena Incision Management System "Prevena" is when placed over a renal transplantation incision. Prevena provides negative pressure (suction) wound therapy.
- Trial name
- PIMS (NCT01341444)
- Testing
- Prevena Incision Management System, Standard of Care for Surgical Incisions
- Where
- United States
- Volunteers
- 63 people
- Sponsor
- KCI USA, Inc
Surgical Site Infection, Post-Op Infection
Analysis of Risk Factors for Surgical Site Infections in Patients With Acute Abdomen at Hospital of State University of Haiti
The purpose of this study is to identify the risk factors associated with surgical site infection.
- Trial name
- NCT06480344
- Where
- Haiti
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- University of Haiti
Surgical Wound Dehiscence, Wound Infection
Prevention of Wound Complications After Cesarean Delivery in Obese Women Utilizing Negative Pressure Wound Therapy
Wound complications after Cesarean section (C-section) are common in obese women. Approximately 25% of obese women having a C-section will have a wound complication.
- Trial name
- NCT00654641
- Testing
- Negative pressure wound closure, Standard wound closure
- Where
- 2 sites in United States
- Volunteers
- 54 people
- Sponsor
- West Virginia University
Incisional Hernia
ProGripTM Self-Gripping Polyester Mesh in Incisional Hernia Prevention
Interventional, prospective, multicenter, post-marketing clinical follow-up study. After midline laparotomy, the probability to develop an incisional hernia ranges from 10% to 50% depending on the complexity of the surgery and…
- Trial name
- POETRY (NCT03912662)
- Testing
- Mesh augmented reinforcement
- Where
- 11 sites in France
- Volunteers
- 32 people
- Sponsor
- Medtronic - MITG
Role of Platelet Rich Plasma in Wound Healing
Local Injection of PRP During Repair of Disrupted Surgical Wounds
Patients with disrupted wounds will either managed as usual or managed by Platelet rich plasma local infiltration in the wound edges
- Trial name
- NCT03781882
- Testing
- Platelet rich plasma infiltration in the wound edges, Closure of wound without platelet rich plasma infiltration
- Where
- Egypt
- Volunteers
- 220 people
- Sponsor
- Tanta University
Surgical Incision
A Comparison Between Two Post-operative Dressings
Surgical site infections are one of the leading causes of post-operative morbidity and mortality worldwide. The ideal post-operative dressing is impermeable and remains intact preventing contamination of the incision with…
- Trial name
- DrySee (NCT04888624)
- Testing
- DrySee® dressing with moisture detection, Tegaderm® + Pad transparent film dressing
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- SerenaGroup, Inc.
Cicatrix, Wound Healing
Investigation Into the Scar Reduction Potential of Prevascar (Interleukin-10)
The purpose of this study was to investigate the scar-reducing properties of eight doses of intradermal Prevascar (IL-10).
- Trial name
- NCT00984646
- Testing
- Prevascar
- Where
- United Kingdom
- Volunteers
- 175 people, healthy volunteers welcome
- Sponsor
- Renovo
Antibiotic, Bowel Cancer
Mechanical Bowel Preparation With or Without Oral Antibiotics for Colorectal Cancer Surgery
Investigation of the role of adding oral antibiotics to preoperative mechanical bowel preparation before colorectal surgery for cancer.
- Conditions
- Antibiotic, Bowel Cancer, Colorectal Cancer, Surgical Site Infection
- Trial name
- MECCA (NCT03563586)
- Testing
- Bowel Preparation plus antibiotics, Bowel Preparation
- Where
- Greece
- Volunteers
- 210 people
- Sponsor
- National and Kapodistrian University of Athens
Elective Abdominal Surgery
Comparison of the Risk of Surgical Site Infections Between Dressings Stopped at Postoperative Day 1 vs Dressings Stopped at Postoperative Day 6+/-1 After Elective Abdominal Surgery
The daily changing of postoperative dressings is a widespread practice, often continuing until the 5th-7th day after surgery. In theory, dressings aim to reduce the risk of superficial surgical site infections (SSIs).
- Trial name
- PAN-STOP (NCT06569862)
- Testing
- Postoperative day 1 dressing, Postoperative day 6+/-1 dressing
- Where
- France
- Volunteers
- 1,288 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Incisional Hernia, Malignancy
Risk Factors for Development of Incisional Hernia in Transverse Incisions
RESEARCH PROJECT OBJECTIVES The aim of this planned study is to evaluate factors, with particular reference to surgical technique of abdominal closure, accumulation of advanced glycation end products, and collagen content in the…
- Trial name
- NCT03561727
- Testing
- Mass closure technique, Layered closure technique
- Where
- Poland
- Volunteers
- 392 people
- Sponsor
- Medical University of Warsaw
Hernia, Abdominal, Recurrence
Nationwide Long-term Outcome Surveillance of Physiomesh® vs. Other Meshes in Laparoscopic Incisional Hernia Repair
The primary aim of the present study was to show how a national clinical register combined with other nationwide administrative registers may serve as a tool for pre- and post-marketing evaluation of new mesh and mesh fixation…
- Conditions
- Hernia, Abdominal, Recurrence, Postoperative Complications
- Trial name
- NCT03846661
- Testing
- Physiomesh
- Where
- Denmark
- Volunteers
- 3,338 people, healthy volunteers welcome
- Sponsor
- Zealand University Hospital
Incidence of Surgical Site Infection, Morality
Changing the Surgical Team for Wound Closure and Surgical Site Infection
Surgical site infection is a frequent complication after abdominal surgery. The wound closure is done at the end of the procedure when the attention of the entire team may be affected because of tiredness and reduced attention of…
- Conditions
- Incidence of Surgical Site Infection, Morality, Fascial Hernia
- Trial name
- NCT04503642
- Testing
- Changing the surgical team for wound closure
- Where
- Switzerland
- Volunteers
- 1,160 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Surgical Site Infection
Betadine Versus Saline in Swapping of Subcutaneous Tissue
Caesarean section is an increasingly common major surgical procedure performed on women. Last decade an overall increase of the global rate of caesarean section, of up to 31.2%, was reported.
- Trial name
- NCT06595823
- Testing
- Betadine
- Where
- Egypt
- Volunteers
- 300 people
- Sponsor
- Egymedicalpedia
Anesthesia, Local
Quadratus Lumborum Block (Transmuscular Approach) VS. TransversusAbdominus Plane Block(Unilateral Posterior Approach) for Perioperative Analgesia in Patients Undergoing Flank Incision Surgeries.
Severe perioperative pain experienced after surgical procedures performed by flank incision is mainly related to incision of many muscles.
- Trial name
- NCT03744923
- Testing
- transmuscular QL block, Transversus Abdominus Plane block
- Where
- Egypt
- Volunteers
- 48 people
- Sponsor
- Cairo University
Cataract Surgery, Cataract (Post-operative Cataract Surgery Follow-up)
Subincisional Pockets for Sealing Clear Corneal Incisions in Cataract Surgery
The main goal of the sub-incisional pocket (SIP) is to provide a wound seal option during corneal surgery. This retrospective cohort study aims to report the efficacy and safety of SIP among eyes undergoing routine cornea surgery…
- Conditions
- Cataract Surgery, Cataract (Post-operative Cataract Surgery Follow-up), Phacoemulsification Cataract Surgery, Wound Closure Technique
- Trial name
- SIPSIP (NCT07821203)
- Testing
- Sub-Incisional Pocket
- Where
- Philippines
- Volunteers
- 35 people
- Sponsor
- Philippine Eye Research Institute
Abscess, Wound Infection
Single Dose vs. Two Dose Regimen of Dalbavancin for the Treatment of Acute Bacterial Skin and Skin Structure Infections
To compare the efficacy of treatment with a single dose of dalbavancin 1500 mg to treatment with a two dose regimen of dalbavancin (1000 mg on Day 1 followed by 500 mg on Day 8) in participants with known or suspected…
- Conditions
- Abscess, Wound Infection, Surgical Site Infection, Cellulitis
- Trial name
- NCT02127970
- Testing
- Dalbavancin
- Where
- 78 sites in United States, Bulgaria and 10 more
- Volunteers
- 698 people
- Sponsor
- Durata Therapeutics Inc., an affiliate of Allergan plc
Arthroplasty Complications, Amputation
Clinical Trial Comparing Negative Pressure Wound Therapy and Standard Dry Dressings
Negative pressure dressings are currently widely used in wound management. Their use is gradually being extended to surgical scars.
- Conditions
- Arthroplasty Complications, Amputation, Prosthesis-Related Infections
- Trial name
- BERLYTZ (NCT04520841)
- Testing
- Prevena TM, Dry dressing
- Where
- Switzerland
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Lausanne Hospitals
Anal Fissure
The Importance of Lateral Internal Sphincterotomy Incision: Parallel or Vertical
The purpose of this study is to determine effective incision type for the treatment of chronic anal fissures.
- Trial name
- NCT00980369
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people
- Sponsor
- SB Istanbul Education and Research Hospital