Clinical trials: Incision, Surgical
Nephrectomy, Partial Nephrectomy
Erector Spinae Plane Block (ESPB): in Patients Undergoing Surgery Through a Flank or Anterior Subcostal Incision.
Using a randomized double-blinded study design, the study goal is to evaluate the superiority of Erector Spinae Plane block (ESPB) in the peri-operative pain management of patients undergoing surgery through a flank or anterior…
- Conditions
- Nephrectomy, Partial Nephrectomy, Incision Site Discomfort
- Trial name
- NCT03691935
- Testing
- Ropivacaine, Normal saline
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Milton S. Hershey Medical Center
Surgical Wound, Breast Surgery
Continuous Diffusion of Oxygen Treatment for Incision Wounds
This is an exploratory randomized controlled trial study to test feasibility, acceptability, and proof of concept efficacy of Continuous Diffusion of Oxygen (CDO) adjunct therapy for decreasing healing time and reducing tissue…
- Conditions
- Surgical Wound, Breast Surgery, Mammoplasty, Incision Wound
- Trial name
- NCT04307355
- Testing
- Transcu O2®, Tegaderm, Silagen
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Baylor College of Medicine
Surgical Wound, Diabetes
EO2 Oxygen Delivery To Study Success Rate of Surgically Closed Wounds
The investigators will test the efficacy of the novel oxygen diffusion dressing allows delivery tissue oxygenation via TransCu O2® Oxygen Delivery System for use in caring for patients with surgically closed wounds.
- Conditions
- Surgical Wound, Diabetes, Amputation Wound, Incision Wound
- Trial name
- NCT03960463
- Testing
- Transcu O2®
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Baylor College of Medicine
Surgical Incision, Minimally Invasive Surgery
Modified Uniportal Periareolar Incision Versus Conventional Uniportal Video-assisted Thoracic Surgery for Pulmonary Nodules: Protocol for a Prospective, Randomized, Controlled Study
Minimally invasive surgical techniques, including the uniportal approach, have become widely adopted in thoracic surgery. Both surgeons and patients aim to achieve incisions that are as minimally invasive and cosmetically…
- Trial name
- NCT06202053
- Testing
- Type of surgical incision
- Where
- China
- Volunteers
- 174 people
- Sponsor
- Fujian Medical University Union Hospital
Keloid, Scar
Safety and Efficacy of AIV001 on Scar Formation and Keloid Recurrence Following Keloidectomy
To evaluate the saftye and effectiveness of AIV001 treatment on scar formation and/or keloid scar recurrence following keloidectomy.
- Conditions
- Keloid, Scar, Incision, Excision Margin
- Trial name
- NCT04827875
- Testing
- AIV001
- Where
- 4 sites in United States
- Volunteers
- 25 people
- Sponsor
- AiViva BioPharma, Inc.
Surgical Incision, Gynecologic Surgery
Postoperative Pain Score of Laparoscopic Gynecological Surgeries
In this study, it was aimed to compare the embryonic route, the umbilicus, and the sub-umbilicus incision in terms of postoperative pain scoring.
- Conditions
- Surgical Incision, Gynecologic Surgery, Postoperative Pain
- Trial name
- NCT05296928
- Testing
- laparoscopic incision
- Where
- Turkey (Türkiye)
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Baskent University
Scar, Incision
A Safety and Efficacy Study to Evaluate AIV001 in Wound Healing Following Surgical Incision
To evaluate the safety, efficacy and pharmacokinetic profile of ascending concentrations of the study medication compared with vehicle in subjects with incisional wounds
- Conditions
- Scar, Incision, Abdominal, Wound (Morphologic Abnormality)
- Trial name
- NCT03639883
- Testing
- AIV001
- Where
- 2 sites in United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- AiViva BioPharma, Inc.
Scar, Skin Scarring
Scar Appearance After Postoperative Hydrocolloid Dressing Versus Standard Petrolatum Ointment
Patients will be randomized either to receive standard daily dressing or hydrocolloid dressing using a randomization generator. After closing the wound with the sutures,the scar will be covered by a hydrocolloid dressing, which…
- Conditions
- Scar, Skin Scarring, Skin Cancer, Wound Heal
- Trial name
- NCT05618912
- Testing
- Hydrocolloid dressing, Petrolatum jelly dressing
- Where
- United States
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- Indiana University
Surgical Incision, Surgical Site Infection
Comparison of the Classical Median Sternotomy Skin Incision with the Paramedian Flap Skin Incision
The goal of this observational study is to determine the effects of a flap-shaped paramedian skin incision on protection from mediastinal infections, wound healing, and scar formation in open heart surgery performed through the…
- Conditions
- Surgical Incision, Surgical Site Infection, Keloid Scar Following Surgery
- Trial name
- NCT06725472
- Testing
- Open Heart Surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Ataturk University
Stress Urinary Incontinence, Surgical Incision
Use of a Dual-agent Local Analgesic (Bupivacaine-meloxicam) for Abdominal Incisions in Patients Undergoing Retropubic Mid-urethral Sling Surgery
This study will compare the use of a dual-agent local analgesic (bupivacaine-meloxicam) for abdominal incisions in patients undergoing retropubic mid-urethral sling surgery to see if narcotic usage and pain are impacted.
- Conditions
- Stress Urinary Incontinence, Surgical Incision, Pain Vulva
- Trial name
- NCT05702827
- Testing
- Bupivacaine-Meloxicam
- Where
- 2 sites in United States
- Volunteers
- 148 people
- Sponsor
- TriHealth Inc.
Linear or Emi-linear Incisions, Total Hip Arthroplasty
Prevena™ Incision Management System Over Primarily Closed Hip and Knee Incisions in Patients Immediately Post Total Hip and Knee Arthroplasty
The intent of this study is to evaluate the Prevena ™ 125 Unit and dressing system, when applied to either the hip or knee area over a surgical cut for the time you are hospitalized.
- Conditions
- Linear or Emi-linear Incisions, Total Hip Arthroplasty, Total Knee Arthroplasty
- Trial name
- Prevena2009-45 (NCT01380665)
- Testing
- Prevena Incisional Management System
- Sponsor
- KCI USA, Inc
Mandibular Angle Fracture, Surgical Approach &Amp; Incisions
Efficacy of Transoral Versus Transbuccal Technique for Fixation of Mandibular Angle Fracture
The goal of this clinical trial is to learn if transbuccal technique for mandibular angle fracture is better than transoral technique.
- Trial name
- NCT06622642
- Testing
- Transoral technique for mandibular angle fracture reduction, Transbuccal technique for mandibular angle fracture reduction
- Where
- Pakistan
- Volunteers
- 68 people
- Sponsor
- Services Institute of Medical Sciences, Pakistan
Surgical Incision, Nose Deformity
Rhinoplasty Scar Comparison
Traditional suture closure of the columellar scar in rhinoplasty is achieved with permanent skin sutures. These sutures create less inflammation and are thought to lead to improved final scar outcomes.
- Trial name
- NCT03748459
- Testing
- Closure with Permanent Suture, Closure with Resorbable Suture
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- Medical University of South Carolina
Peritonsillar Abscess, Surgical Incision
Medical Versus Surgical Treatment for Peritonsillar Abscesses
Peritonsillar abscesses are major infections around the tonsils. The abscess is a collection of pus that can cause a large amount of pain and discomfort, which can result in trouble swallowing and drinking.
- Trial name
- NCT04998513
- Testing
- Medical Management Alone Arm, Surgical Arm
- Sponsor
- Nova Scotia Health Authority
Surgical Incisions
Clinical Trial To Study The Anti-scarring Effect Of Cicatricell
This study tries to prove that Cicatricell cream significantly reduces scarring with better wound appearance as compared to no treatment.
- Trial name
- Cicatricell (NCT03020420)
- Testing
- Cicatricell Cream
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- University of Toledo Health Science Campus
Surgical Incision
Silk Scaffold Surgical Incision Dressing
Interventional Study of the novel clinical application of SERI surgical silk scaffold affixed with dermaFLEX medical adhesive as a wound dressing, compared to two separate current standard of care for surgical incision closure…
- Trial name
- SSSID (NCT05508945)
- Testing
- Dermabond Prineo Skin Closure System, silk, 3M Steri-Strip
- Where
- United States
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Mehrdad Mark Mofid
Laceration, Incision
Optilene® Suture Material for Dermal Sutures
In this non-interventional study, Optilene® suture will be evaluated for skin closure in adult patients.
- Trial name
- OPTIDERMAL (NCT05240248)
- Where
- Spain
- Volunteers
- 172 people
- Sponsor
- Aesculap AG
Carpal Tunnel Syndrome, Incision
Comparing a Modified Mini-incision Approach Versus the Conventional Approach for Carpal Tunnel Release
Carpal tunnel syndrome (CTS) is the commonest nerve compression syndrome in the upper limbs, and carpal tunnel decompression is one of the most prevalent upper limb surgical interventions.
- Trial name
- NCT06114823
- Testing
- carpal tunnel release mini-incision, carpal tunnel release conventional incision
- Where
- Egypt
- Volunteers
- 68 people
- Sponsor
- Mansoura University
Wound Infection, Surgical Site Infection
Prophylactic Closed Incision Negative Pressure Wound Therapy on Abdominal Wounds - Clinical and Economic Perspectives
This study evaluates whether specialist negative pressure dressings reduce the risk of wound infections after operations when compared to conservative dressings, and if one negative pressure dressings works better than another.
- Conditions
- Wound Infection, Surgical Site Infection, Surgical Wound, Surgical Incision
- Trial name
- ProNounCE (NCT04110353)
- Testing
- Wound dressings: Conservative dressings, Wound dressings: Prevena dressings, Wound dressings: ciVAC dressings
- Sponsor
- Imperial College London
Blepharoptosis, Ptosis, Eyelid
Blepharoptosis in Indonesia: A 5-Year Multicenter Study on Characteristics and Surgical Evaluation
The goal of this observational study is to learn about blepharoptosis cases in national referral hospitals in Indonesia. The main questions it aims to answer are: How is the clinical characteristics, types, and surgical…
- Conditions
- Blepharoptosis, Ptosis, Eyelid, Characteristics Disease, Surgical Incision
- Trial name
- NCT06047418
- Testing
- Blepharoplasty
- Where
- Indonesia
- Volunteers
- 823 people
- Sponsor
- Universitas Indonesia