Clinical trials: In Vitro Fertilization
Infertility
Assessment of Two Methods for Progesterone Dosage During IVF
Nowadays, 1/7 couple consult because of infertility and some of them will need in vitro fertilization +/- intracytoplasmic sperm injection (IVF+/- ICSI).
- Trial name
- SALIPROG (NCT05987657)
- Testing
- Salivary and blood progesterone dosage
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Hospices Civils de Lyon
Infertility (IVF Patients)
Study of Abnormally Fertilized Embryos
The goal of this observational study is to determine the diploidy rate of haploid and triploid embryos from in vitro fertilization (IVF) cycles.
- Trial name
- SAFE (NCT06940973)
- Testing
- Parental samples, PGT-A, TE rebiopsies and spent blastocyst media collection
- Where
- Spain
- Volunteers
- 300 people
- Sponsor
- Igenomix
Infertility
Study Comparing Outcomes Between Conventional IVF and a "Freeze-all"-Strategy in Assisted Reproductive Technology
The purpose of this study is to compare conventional fresh embryo transfer with a "freeze all and transfer later strategy" in assisted reproductive technology in terms of ongoing pregnancy rates, live birth rates as well as…
- Trial name
- NCT02746562
- Testing
- Freeze all
- Where
- 2 sites in Denmark
- Volunteers
- 424 people
- Sponsor
- Anja Bisgaard Pinborg
Infertility
Does Letrozole Improve the Outcomes and/or Reduce the Cost of IVF-ET Cycles?
This research is being done to determine whether the success rate of in vitro fertilization treatment can be improved, while lowering the cost incurred from infertility medications using a pill called letrozole.
- Trial name
- Cost-Less (NCT00804960)
- Testing
- Letrozole, Std IVF Protocol
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Center for Human Reproduction
Male Infertility
A Novel Sperm Selection Method Provides Advantages Over Conventional Approaches
The goal of this clinical trial is to know if a novel sperm selection device (CA0) has a similar performance than the standard selection method in teratozoospermic and azoospermic men.
- Trial name
- NCT06545318
- Testing
- Density Gradient Centrifugation, CA0 chamber
- Where
- Mexico
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- Center of Innovation Technology & Reproductive Medicine
Infertility (IVF Patients), Acupuncture
Evaluation of Acupuncture's Effectiveness on Pregnancy Outcomes in Women with Recurrent Implantation Failure RIF: a Large Cohort Study
Title: Evaluating the Effectiveness of Acupuncture on Pregnancy Outcomes in Recurrent Implantation Failure (RIF) Patients Undergoing In Vitro Fertilization (IVF): A Large Cohort Study Objective: This study aims to assess the…
- Trial name
- AcupunctureRIF (NCT06708923)
- Testing
- Intervention Name: Acupuncture Therapy Before and After Embryo Transfer Description: The intervention involves acupuncture therapy performed at two key time points during the IVF cycle: 25 minutes be
- Where
- Vietnam
- Volunteers
- 1,969 people, healthy volunteers welcome
- Sponsor
- Hung Vuong Hospital
Infertility, Poor Ovarian Reserve
Growth Hormone for Poor Responders in in Vitro Fertilization (IVF)
The purpose of this study is to determine if growth hormone given 4 weeks before as well as during a cycle of in vitro fertilization will improve outcomes in women who have had previous failure with IVF treatment cycles using…
- Trial name
- NCT01204840
- Testing
- Growth Hormone, Patch protocol
- Where
- Canada
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Ottawa Fertility Centre
Sub Fertility, Female, Fertility Disorders
Effects of Fasting on Success Rates of Assisted Reproductive Techologies
This exploratory study investigates fasting as a potential supportive therapy for infertility treatment in women undergoing in-vitro-fertilization (IVF) / intracystoplamsatic sperm injection (ICSI)
- Conditions
- Sub Fertility, Female, Fertility Disorders, Fertility Issues, Sub-fertility
- Trial name
- KiWuC (NCT04998591)
- Testing
- Fasting
- Where
- Germany
- Volunteers
- 1 people
- Sponsor
- Charite University, Berlin, Germany
Subfertility, Assisted Reproduction
Role of Follicular Output Rate in the Prediction of in Vitro Fertilization and Intracytoplasmic Sperm Injection in Women With Unexplained Infertility
300 women with unexplained infertility who are already decided to be treated with ICSI will be recruited from Cairo university hospitals and Dar Al-Teb subfertility centre.
- Trial name
- NCT02154958
- Where
- 2 sites in Egypt
- Volunteers
- 300 people
- Sponsor
- Cairo University
Ovarian Response
Human Chorionic Gonadotropin (hCG) Priming Prior to Controlled Ovarian Hyperstimulation (COH) in Poor Responder In Vitro Fertilization (IVF) Patients
There is a decline in androgen concentration with ovarian aging. Also, ovarian response to COH in IVF cycles diminishes with ovarian aging.
- Trial name
- APPE (NCT00870025)
- Testing
- human chorionic gonadotropin
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- IVI Madrid
Infertility
Day of Embryo Transfer for Patients Undergoing In Vitro Fertilization
We are examining whether pregnancy rates differ based on day of embryo transfer in patients who replace all available embryos after an In vitro Fertilization (IVF) cycle.
- Trial name
- NCT00615771
- Testing
- Day 3 embryo transfer, Day 2 embryo transfer
- Where
- United States
- Volunteers
- 242 people
- Sponsor
- Stanford University
Infertility, Oocytes
Efficacy of a Simulator Based (PickUpSimTM) Residents' Training Program for Oocyte Retrievals
Simulation is an educational approach that has recently found an application in healthcare.acquire. Angers university hospital has decided to acquire, in December 2016, the high-fidelity Oocyte Pick up (OPU) simulator…
- Conditions
- Infertility, Oocytes, Fertilization in Vitro
- Trial name
- NCT03700255
- Testing
- PickUpSimTM simulation training program
- Where
- France
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Poor Responders Undergoing IVF
The Comparison of Effect of Four Different Treatment Protocols on IVF Outcomes in Poor Responders Undergoing in Vitro Fertilization.
The comparison of effect of four different treatment protocols: Antagonist/letrozole protocol, microdose flare-up protocol, Antagonist/clomiphene protocol, Antagonist on IVF outcomes in poor responders undergoing in vitro…
- Trial name
- NCT01948804
- Testing
- GnrH Antagonist/letrozole protocol (Cetrotide; serono + Femara; Novartis Pharma AG), microdose flare-up protocol (Lucrin; Abbott + Gonal F, Serono), Antagonist/clomiphene protocol (Cetrotide; serono + Klomen, Kocak pharma)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Pınar Özcan Cenksoy
IVF, Infertility
Improvement of Fertilization Rate and Embryo Quality by Treating Calcium Ionophore in IVF Patients: a Sibling Oocyte Control Study
GM508 CultActive is a bicarbonate buffered reagent and ready-to-use designed to investigate oocytes of patients with failed fertilization after previous Intracytoplasmatic Sperm Injection cycles.
- Conditions
- IVF, Infertility, Artificial Oocyte Activation
- Trial name
- GM508 in IVF (NCT05722067)
- Testing
- calcium ionophore
- Where
- Taiwan
- Volunteers
- 68 people
- Sponsor
- Chang Gung Memorial Hospital
Endometriosis, Infertility
Endometrial Markers and Response of Endometriosis Patients to Prolonged GnRH Agonist Prior to IVF
This prospective randomized trial evaluates whether one can predict which infertile women with endometriosis who are candidates for in vitro fertilization will benefit from prolonged therapy with a GnRH agonist by the…
- Trial name
- IntegrinIVF (NCT00621179)
- Testing
- Leuprolide acetate in depot suspension, No intervention
- Where
- United States
- Volunteers
- 37 people
- Sponsor
- Colorado Center for Reproductive Medicine
Infertility
Dehydroepiandrosterone (DHEA)Supplementation Pre-IVF(In Vitro Fertilization) Cycles
The purpose of this study is to compare the effect of pre-IVF cycles treatment with and without DHEA(Dehydroepiandrosterone) on the ovarian reserve markers, the number of oocytes obtained and IVF(in vitro fertilization) outcomes…
- Trial name
- IVF (NCT02866253)
- Testing
- DHEA
- Volunteers
- 78 people
- Sponsor
- ShangHai Ji Ai Genetics & IVF Institute
Pregnancy
Correlation Between PIF Maternal Serum Levels and Pregnancy Outcome
PIF: biomarker of pregnancy, miscarriage, premature birth, preeclampsia, placenta accreta. Except for serum hCG, no pregnancy-complication markers are widely employed to predict the need for medical intervention.
- Trial name
- PIFBlood1 (NCT01805102)
- Where
- 5 sites in United States, France and 1 more
- Volunteers
- 500 people
- Sponsor
- BioIncept LLC
Infertility, Female, Endometrial Diseases
Effect of Different Ovarian Stimulation Protocols on Endometrial Receptivity
This study will assess the change in endometrial gene expression signature on the day of embryo transfer according to the type of exogenous gonadotropins administered.
- Trial name
- NCT03755973
- Testing
- CFA, rFSH, Fixed daily rFSH dosing protocol of 200-300 IU
- Where
- Portugal
- Volunteers
- 24 people
- Sponsor
- Instituto Valenciano de Infertilidade de Lisboa
Infertility
Ultrasound-guided Hydrosalpinx Aspiration During Egg Collection
· What we know: Hydrosalpinx and IVF About 40% of patients undergoing IVF have tubal disease and in 25%-30% of tubal disease patients there is fluid collection within the tube; hydrosalpinx.
- Trial name
- NCT00566956
- Testing
- Hydrosalpinx needle aspiration to arm 1
- Where
- United Kingdom
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Birmingham Women's NHS Foundation Trust
Hydrosalpinx
Three Dimensional Versus Two Dimensional Laparoscopic Salpingectomy in Patients With Hydrosalpinx Undergoing IVF-ET
A three-dimensional laparoscopic vision system (3-D LVS) has gained acceptance and is being utilized in daily practice despite debates about its success.
- Trial name
- NCT05195073
- Testing
- Laparoscopy
- Where
- Egypt
- Volunteers
- 36 people
- Sponsor
- Cairo University