Clinical trials: Impulse Control Disorders
Pathological Gambling
An Open-Label Study of N-Acetyl Cysteine in Pathological Gambling
After completing all screening evaluations, subjects will receive unblinded N-Acetyl Cysteine 600 mg/day for 2 weeks. The dose will be raised to 1200 mg/day at visit 4 and to 1800 mg/day at visit 6 unless clinical improvement has…
- Trial name
- NCT00273702
- Testing
- N-Acetyl Cysteine
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Migraine Disorders, Brain, Healthy Adult Participants
Effect of Atogepant on the Vestibulo-Ocular Reflex in Healthy Adults and Adults With Migraine
Researchers want to find out how a substance in the body called CGRP affects balance. CGRP (calcitonin gene-related peptide) is a small protein involved in migraine. Several approved migraine medicines work by blocking it.
- Conditions
- Migraine Disorders, Brain, Healthy Adult Participants, Vestibulo-Ocular Reflex
- Trial name
- VOR-GRIP (NCT07826910)
- Testing
- Atogepant 60 mg
- Where
- Switzerland
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Konrad Peter Weber
Gambling, Pathological
Adding Contingency Management to Treatment as Usual for Disordered Gambling.
The aim of this study is to conduct a trial to investigate the efficacy of adding Contingency Management (CM) to Treatment as Usual (TAU) for the treatment of Disordered Gambling.
- Trial name
- NCT02613754
- Testing
- Contingency Management, Treatment as Usual
- Where
- Canada
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Lethbridge
Gambling Disorder
Effect of High-Intensity Transcranial Alternating Current Stimulation on Gambling Disorder: A Randomized Controlled Trial
The investigators assume that High-intensity transcranial Alternating Current Stimulation (HI-tACS) could improve gambling disorder patients' executive-control function by modulating abnormal neural activity, particularly…
- Trial name
- HITACSRCT-GD (NCT07228182)
- Testing
- HI-tACS
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Shanghai Mental Health Center
Addictive Behaviors, Internet Addiction Disorder
Is Craving a Central Criterion for Diagnosing a Behavioral Addiction?
This study is a cross-sectional observational study designed to evaluate the diagnostic criteria for behavioral addictions (gambling, online video game disorder, screen addiction, food addiction, and pathological use of sex…
- Conditions
- Addictive Behaviors, Internet Addiction Disorder, Gambling, Technology Addiction
- Trial name
- CRIBA (NCT07854912)
- Testing
- Questionnaires, Telephone interview
- Where
- France
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Bordeaux
Gambling
Drug Treatment for Pathologic Gambling Disorder
This study will establish the best dose of the drug naltrexone to treat patients with Pathological Gambling Disorder (PGD) and severe urge symptoms.
- Trial name
- NCT00053677
- Testing
- Naltrexone
- Where
- United States
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Intermittent Explosive Disorder
Effect of Nitrous Oxide on Aggression.
The goal of this experimental medicine clinical trial is to test the hypothesis that nitrous oxide inhalation will result in a change in neurocircuit function in healthy controls and in individuals with impulsive aggressive…
- Trial name
- NCT06118567
- Testing
- Nitrous oxide, Room Air
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Gambling
Prevention Messages for EGMs: Effects on Behaviours and Cognitions
The goals of this randomized controlled trial are to test the manifold effects of prevention pop-up messages on participants' behaviours, cognitions and affects.
- Trial name
- NCT06341504
- Testing
- Prevention pop-up messages, Mandatory time limit, Responsible gambling information
- Where
- Canada
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Benjamin Galipeau
Gambling
Evaluation of Effectiveness of the Unplugged Program on Gambling Among Adolescents (GAPUnplugged)
The main aim of this study is to assess the effectiveness of a new component on gambling prevention to be added to the evidence-based school based prevention curriculum "Unplugged".
- Trial name
- GAPUnplugged (NCT05630157)
- Testing
- Unplugged plus gambling component
- Volunteers
- 3,046 people, healthy volunteers welcome
- Sponsor
- Università degli Studi del Piemonte Orientale Amedeo Avogadro
Pathological Gambling
D1 and D2 Dopamine Receptors in Gambling and Amphetamine Reinforcement
To determine if: 1. pathological gambling is similar to psychostimulant addiction as reflected by parallel roles for D1 and D2 receptors in gambling and stimulant reinforcement. 2.
- Trial name
- HFDEX (NCT02203786)
- Testing
- Haloperidol, Fluphenazine, Dexedrine
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Centre for Addiction and Mental Health
COPD, Small Airway Disease
The Prevalence of Small Airways Dysfunction In COPD Patients and The Impact on COPD Control
Chronic obstructive pulmonary disease (COPD) is a worldwide prevalent disease. During recent years, increasing attention has been directed to the importance of the contribution of small airways in respiratory diseases.
- Trial name
- NCT04384133
- Testing
- Impulse oscillometry, Spirometric pulmonary function test, Fractional exhaled nitric oxide (FENO) test
- Where
- Turkey (Türkiye)
- Volunteers
- 170 people, healthy volunteers welcome
- Sponsor
- Sibel Naycı
Gambling Addiction
Testing the Interplay of Gambling, Emotion and Reward
Background The nature and direction of dysfunctional reward processing in gambling disorder remains unclear. We aim to test a novel neurobiological model of gambling addiction, that takes into account inter-individual…
- Trial name
- TIGER (NCT06122298)
- Testing
- fMRI, Ecological Momentary Assessment
- Where
- France
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Hôpital le Vinatier
Gambling
The Effect of Regular Naltrexone Dosing on Disordered Gamblers
This study examines the effect of regular naltrexone dosing on disordered gamblers. Gamblers will also be scanned pre- and post-treatment where we will investigate the functional changes to tasks designed to engage brain region…
- Trial name
- NCT02537197
- Testing
- Naltrexone
- Where
- Canada
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Drug Addiction, Vulnerability to Substance Addiction
Individual Differences in Reward and Impulse Control
Background: The risk for becoming addicted to drugs varies among individual, even those using similar drugs in a similar way. It is not known why some people become addicted and others do not.
- Trial name
- NCT01621607
- Where
- United States
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- National Institute on Drug Abuse (NIDA)
Gambling Disorder, Gambling Problem
Beliefs About Mental Health Treatment - Gambling Addiction Study in Colorado
Many people with mental health conditions do not seek treatment, and it is unclear what exactly prevents people from taking up treatment.
- Conditions
- Gambling Disorder, Gambling Problem, Mental Health Issue
- Trial name
- NCT06517849
- Testing
- Monetary Incentive for Take-Up of Cognitive Behavioral Therapy
- Volunteers
- 375 people, healthy volunteers welcome
- Sponsor
- Stanford University
Parkinson Disease, Impulse Control Disorders
Serotonin in Impulse Control Disorders in Parkinson's Disease
Impulse control disorders are frequent and troublesome in patients with Parkinson's disease. However, the cerebral functional alterations related to impulse control disorders in Parkinson's disease are poorly understood and may…
- Trial name
- Park-IMPULSE (NCT03970239)
- Testing
- Positron Emission Tomography using [11 Carbon]-3-amino-4-(2-dimethylaminomethylphenylsulfanyl)-benzonitrile ([11C]-DASB) and [18 Fluorine]-altanserin ([18F]-altanserin), Positron Emission Tomography using [18 Fluorine]-altanserin ([18F]-altanserin)
- Where
- France
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Pathological Gambling, Gambling Disorder
Effects of Intranasal Naloxone on Gambling Urges and Craving in Gambling Disorder
Primary objective: *To determine whether treatment with naloxone hydrochloride nasal spray reduces gambling urge symptoms in patients with gambling disorder The secondary objectives of the study are: To determine the effects of…
- Conditions
- Pathological Gambling, Gambling Disorder, Opioid Antagonist, Naloxone
- Trial name
- NalGamb (NCT03430180)
- Testing
- Naloxone hydrochloride
- Where
- Finland
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Finnish Institute for Health and Welfare
Asperger's Disorder, Asperger Disorder
QAIAx (AIhealth4U) - AI Smart Health Cities: Microcity Enclave Program (Quantum AI/AGI Agency a/k/a AI City Hall Project - UPSTO App Nos. 64/074,526, 64/063,557, 64/105,164, 63/903,181, 63/729,428, 64/125,360)
BRIEF SUMMARY A. "What is the purpose of this study?" BACKGROUND. The QAIAx clinical trial (Quantum AI/AGI Public Health Agency), known operationally as the "AI City Hall Project," represents a landmark intergovernmental research…
- Conditions
- Asperger's Disorder, Asperger Disorder, Autism Disorder, Autism
- Trial name
- QAIAx (NCT07661823)
- Testing
- AI City Hall Project (AIhealth4u - Public Health Central), AI City Hall Project (QAIAx Microcity A - AI Public Health Central)
- Where
- United States
- Volunteers
- 1,000,000 people, healthy volunteers welcome
- Sponsor
- Veterans Recovery Network Inc.
Anger, Intermittent Explosive Disorder
Maladaptive Anger Treatment
From a psychoevolutionary perspective, anger is a universal emotion that can serve the function of making us aware of wrongdoing and motivating us to undo/correct the wrongdoing.
- Conditions
- Anger, Intermittent Explosive Disorder, Emotional Distress, Aggression
- Trial name
- NCT06275607
- Testing
- Cognitive Behavioral Affective Therapy, Emotional Discussion
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- The University of Texas at San Antonio
Gambling Disorder
Online Intervention to Promote Change and Help-Seeking in Young Adults With Gambling and Trading Problems
The goal of this study is to investigate if personalized online normative feedback (PONF) can increase intention to change and help-seeking behaviors in young adults with gambling or trading problems in Spain.
- Trial name
- NCT06681103
- Testing
- Personalized Normative Feedback
- Where
- Spain
- Volunteers
- 1,112 people, healthy volunteers welcome
- Sponsor
- Universidad Miguel Hernandez de Elche