Clinical trials: Implementation Science
Food Insecurity, Dietary Quality
Behavioral Economics to Implement Nutrition Ranking in Food Pantries
The goal of this randomized controlled trial is to test whether using behavioral economic strategies to promote healthy food choices on a food bank's online ordering platform increases the use of the traffic light nutrition…
- Conditions
- Food Insecurity, Dietary Quality, Behavioral Economics, Implementation Science
- Trial name
- NCT05854212
- Testing
- Behavioral economics-enhanced user interface
- Where
- United States
- Volunteers
- 364 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Behavior, Health Risk, Implementation Science
Incentive-based and Media Literacy Informed Approaches to Improve Vaping Cessation
This study aims to evaluate the feasibility and compare the preliminary effect of vaping cessation program consisting of media literacy education and real-time text messaging support and leverage insights from behavioral…
- Conditions
- Behavior, Health Risk, Implementation Science, E Cigarette Use, Cessation, Smoking
- Trial name
- NCT05586308
- Testing
- Text-massaging suport, Financial incentive, Media literacy
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Nebraska
Cardiovascular Diseases, Overweight
Enhancing Mental and Physical Health of Women Veterans 3.0
Women Veterans are the fastest growing segment of VA users, with most users in midlife. This dramatic growth has created challenges for VA to ensure that appropriate services are available to meet women Veterans' needs, and that…
- Conditions
- Cardiovascular Diseases, Overweight, Obesity, Hypertension
- Trial name
- EMPOWER (NCT07356479)
- Testing
- EBQI Booster (EBQI/B), EBQI Booster + External Facilitation (EBQI/B+EF)
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- VA Office of Research and Development
Accidental Injuries, Global Child Health
The P-KIDs CARE Health Systems Intervention in Tanzania
The objective of the proposed research is to develop and pilot a locally-relevant, multicomponent intervention to streamline the triage process (e.g.
- Conditions
- Accidental Injuries, Global Child Health, Pediatric Emergency Medicine, Public Health System Research
- Trial name
- P-KIDs CARE (NCT06075108)
- Testing
- P-KIDs CARE
- Where
- Tanzania
- Volunteers
- 284 people
- Sponsor
- University of Utah
Implementation Science, Diet, Food, and Nutrition
Sustainability Via Active Garden Education Wellness Implementation Strategies in Early Care and Education
This project compares four SAGE implementation strategies to evaluate effectiveness in implementation, sustainability, cost, and child health outcomes.
- Conditions
- Implementation Science, Diet, Food, and Nutrition, Child Care, Motor Behavior
- Trial name
- SAGE WISE (NCT07228819)
- Testing
- SAGE Basic, SAGE e-support, SAGE in-person support
- Where
- United States
- Volunteers
- 871 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Adolescent HIV Infection, Transition to Adult Care
Scale-up of an Evidence-based Adolescent Transition Package to Support Transitional Care Among Youth Living With HIV
Ending the HIV epidemic for youth living with HIV will require implementation and optimization of evidence-based interventions that address barriers to treatment.
- Conditions
- Adolescent HIV Infection, Transition to Adult Care, Implementation Science, Implementation Strategies
- Trial name
- ATTACH-Scale (NCT06924073)
- Testing
- ATP-Youth Enhanced Strategy (ATP-YES)
- Where
- 25 sites in Kenya
- Volunteers
- 1,920 people, healthy volunteers welcome
- Sponsor
- University of Washington
Blood Culture Rates, Antibiotic Stewardship
BrighT STAR LIBRA: Leveraging Implementation Science for Blood Culture Reduction Approaches
This study will compare two strategies that target distinct determinants of blood culture overuse in an exploratory, hybrid, pilot trial in 8 PICUs.
- Conditions
- Blood Culture Rates, Antibiotic Stewardship, Implementation Science
- Trial name
- LIBRA (NCT06187662)
- Testing
- Checklist, Targeted Messaging
- Where
- 8 sites in United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Philadelphia
Fatty Liver, Nonalcoholic, Weight Loss
Feasibility of Immersive Virtual Reality Dietician Program in Metabolic-dysfunction Associated Steatotic Liver Disease
Metabolic-dysfunction associated steatotic liver disease, often referred to as "fatty liver disease", is a leading cause of liver failure.
- Conditions
- Fatty Liver, Nonalcoholic, Weight Loss, Virtual Reality, Implementation Science
- Trial name
- NCT06215131
- Testing
- In-person dietary weight loss counseling, Virtual reality dietary weight loss counseling
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Milton S. Hershey Medical Center
Infusions, Intravenous, Implementation Science
Validation of the Effectiveness of the CFIR - ERIC Matching Tool in Implementation Research
The goal of this implementation study is to learn if the CFIR-ERIC matching tool is effective indeveloping implementation strategies for pediatric nurse.
- Trial name
- NCT07184489
- Testing
- implementation strategies
- Where
- China
- Volunteers
- 394 people
- Sponsor
- Children's Hospital of Fudan University
Implementation Science
An Exposure-Based Implementation Strategy to Decrease Clinician Anxiety Around Suicide Prevention
Study objectives are to design and pilot test a novel, exposure-based implementation strategy (EBIS) directly targeting clinician anxiety and low self-efficacy for use of evidence-based suicide screening, assessment, and…
- Trial name
- NCT05172609
- Testing
- Exposure Based Implementation Strategy (EBIS), Implementation as Usual (IAU)
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Ankle Sprains, Telerehabilitation
Telehealth Delivered Physical Rehabilitation for an Ankle Sprain
A vast majority (75-85%) of ankle sprain patients treated in emergency departments (ED) receive pain medication and are not referred for physical rehabilitation.
- Conditions
- Ankle Sprains, Telerehabilitation, Analgesic, Opioid, Analgesics, Non-narcotic
- Trial name
- NCT04520854
- Testing
- Telehealth Protocol, Usual Care
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- Kyle Kosik
Medication Therapy Management, Implementation Science
Senior PharmAssist: Co-Design and Evaluation of a Toolkit to Promote Scalable Implementation
This project aims to evaluate the scalability of an established, evidence-based, multi-component intervention, Senior PharmAssist^TM (SPA), designed to improve function and quality of life of older adults with limited incomes.
- Trial name
- NCT05278650
- Testing
- Senior PharmAssist^TM Program Implementation
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Duke University
Inappropriate Prescribing, Implementation Science
De-implementation of Low-value Pharmacological Prescriptions
The De-imFAR study is a two phase study that aims to carry out and test a structured, evidence-based and theory informed process involving the main stakeholders (managers, professionals, patients and researches) for the design…
- Conditions
- Inappropriate Prescribing, Implementation Science, Behavioral Sciences
- Trial name
- De-imFAR (NCT04022850)
- Testing
- A non-reflective decision assistance strategy, A both reflective and non-reflective decision information strategy, A reflective decision structure strategy
- Where
- Spain
- Volunteers
- 348 people, healthy volunteers welcome
- Sponsor
- Basque Health Service
Mental Health, Psychosocial Functioning
RESETTLE-IDPs: Life-Skills Education and Psychosocial Resilience Building for Displaced Nigerians
The RESETTLE-IDPs study aims to address the urgent mental health needs of internally displaced youth and women in Nigeria, who face high rates of depression, anxiety, and post-traumatic stress due to exposure to conflict…
- Conditions
- Mental Health, Psychosocial Functioning, Implementation Science, Global Health
- Trial name
- RESETTLE-IDPs (NCT06412679)
- Testing
- Life Skills Education
- Where
- Nigeria
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Dalhousie University
Implementation Science, Transportation of Patients
Implementation Study of Intra-hospital Transfer of Pediatric Inpatients
This study implemented the "Clinical Practice Guidelines for In-hospital Transfer of Pediatric Inpatients (2023 edition)" released by the research team in June 2023 in real clinical settings.
- Trial name
- NCT06512805
- Testing
- Routine transport, Post-guideline transfer
- Where
- China
- Volunteers
- 214 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Fudan University
Emergency Laparotomy, Quality Improvement
Quality Improvement Audit of ERAS Protocol Adherence in Emergency Laparotomy
This study evaluates the implementation of Enhanced Recovery After Surgery (ERAS) protocols during emergency laparotomy procedures in a resource-limited hospital in Sudan.
- Conditions
- Emergency Laparotomy, Quality Improvement, Implementation Science, Enhanced Recovery After Surgery (ERAS) Protocol
- Trial name
- NCT06757127
- Testing
- ERAS Protocol Adaptation for Emergency Laparotomy
- Where
- Sudan
- Volunteers
- 40 people
- Sponsor
- Sudan Medical Specialization Board
Sexually Transmitted Diseases, HIV Infections
UTECH: Machine Learning for HIV Prevention Among Substance Using GBMSM
This project seeks to develop and test the acceptability, appropriateness and feasibility of uTECH, a novel social media "big data" machine learning intervention for HIV-negative substance-using sexual and gender minority people…
- Conditions
- Sexually Transmitted Diseases, HIV Infections, Implementation Science, Substance Use
- Trial name
- uTECH (NCT04710901)
- Testing
- uTECH + YMHP, YMHP, uTECH
- Where
- United States
- Volunteers
- 388 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Implementation Science, Contact Tracing
Developing and Testing a Social Network Data Capture Tool to Improve Partner Services: a Preliminary Pilot Implementation
This study conducted a preliminary pilot implementation which integrated our existing social network software - Network Canvas - into Chicago Partner Services in order to understand the feasibility and acceptability of this…
- Conditions
- Implementation Science, Contact Tracing, Public Health System Research
- Trial name
- NCT06659003
- Testing
- Pilot Implementation of Network Canvas into HBH Partner Services
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Northwestern University
Implementation Science, Stroke
Embedding the Fugl-Meyer Assessment in Occupational Therapists' Routine Practice
Background: Using outcome measures is emphasized in foundational training and clinical practice guidelines, but less than 50% of rehabilitation professionals consistently use outcome measures in practice.
- Trial name
- NCT05374239
- Testing
- Multi-component implementation intervention
- Where
- Singapore
- Volunteers
- 4 people
- Sponsor
- Singapore General Hospital
Implementation Science
Implementation of Two Transdiagnostic Interventions Based on Emotional Regulation (DBT and UP) for Alcohol Addiction
The aim of this study is to evaluate the dissemination and implementation process of two transdiagnostic psychological interventions (Dialectical Behavioral Therapy for Substance Use Disorders-DBT-SUD and Unified Protocol-UP) to…
- Trial name
- NCT06366100
- Testing
- Dialectical Behavior Therapy for Substance Use Disorder (DBT-SUD), Unified Protocol (UP)
- Where
- Spain
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Universidad de Zaragoza