Clinical trials: Implementation
Substance Abuse
Preventing Substance Use Among Youth
Using a 2-group, mixed method group randomized trial design, this pilot study will compare standard implementation versus Enhanced Replicating Effective Programs (Enhanced REP) to deliver Michigan Model for Health (MMH) in…
- Trial name
- NCT04752189
- Testing
- Enhanced Replicating Effective Programs (Enhanced REP), Standard implementation
- Where
- United States
- Volunteers
- 825 people, healthy volunteers welcome
- Sponsor
- Wayne State University
Head Injury, Sport Injury
Implementation of an Evidence-Based Intervention to Improve Head Impact Safety in Youth Football
The objective of this study is to evaluate the feasibility of implementing an evidence-based intervention program, COmmunities Aligned to reduce Concussion and Head impact exposure (COACH) on a larger scale.
- Trial name
- NCT06368050
- Testing
- practice structure intervention
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Drug Abuse, Nicotine Dependence
Cognitive Task Development and Implementation for Functional MRI Studies
Background: Drugs of abuse have effects on mood, behavior, thinking, and decision making that may encourage people to continue using them and make it difficult for them to stop.
- Trial name
- NCT01036685
- Where
- United States
- Volunteers
- 525 people, healthy volunteers welcome
- Sponsor
- National Institute on Drug Abuse (NIDA)
Father-Child Relations, Depression
Mental Health Treatment to Improve Father Depression and Child Outcomes in Kenya
The goal of this study is to evaluate the feasibility and acceptability of a peer-father counselor delivered psychosocial intervention for fathers at risk for depression and some alcohol use in Eldoret, Kenya in a pilot…
- Conditions
- Father-Child Relations, Depression, Alcohol Use, Unspecified
- Trial name
- NCT06489314
- Testing
- LEAD (Learn, Engage, Act, Dedicate)
- Where
- Kenya
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Florida International University
Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8
Geriatric Care Survivorship Intervention for Improving the Overall Health of Older Adults With Stage I-III Breast Cancer Who Have Completed Curative Treatment
This trial studies the effect of a geriatric care survivorship intervention in improving the overall health of older adults who have completed curative treatment for stage I-III breast cancer.
- Conditions
- Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8, Anatomic Stage III Breast Cancer AJCC v8
- Trial name
- NCT05928325
- Testing
- Comprehensive Geriatric Assessment, Health Education, Medical Device Usage and Evaluation
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Anemia, Nutritional Status
Long-term Effectiveness and Implementation of the Meals, Education, and Gardens for In-School Adolescents Program
The overall objective of the proposed study is to determine the longer-term effectiveness and implementation of an updated school-based nutrition intervention package for reducing adolescent malnutrition.
- Trial name
- MEGA 2 (NCT07092150)
- Testing
- School meals, School gardens, IFA and Deworming
- Where
- Tanzania
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Harvard School of Public Health (HSPH)
Concussion, Brain Trauma
Field Implementation of iDETECT
The purpose of this study is to assess a new screening tool for sideline evaluation of concussion injuries in athletes. iDETECT is a new technology that combines several elements of recommended concussion screening tools into a…
- Trial name
- NCT02529618
- Testing
- integrated Display Enhanced Testing for Cognitive Impairment and mild traumatic brain injury (iDETECT), Riddell High Impact Technology (HIT) System, i1 Biometrics Vector Mouth Guard
- Where
- 4 sites in United States
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Emory University
Palliative Care, Dementia
Implementation of a Telehealth Palliative Care Model for Persons With Dementia
Grounded in the Reach-Effectiveness-Adoption-Implementation-Maintenance (RE-AIM) Model, this study will assess the implementation outcomes of the Nurse Practitioner (NP) delivered telehealth Palliative Care Consultation in…
- Trial name
- IMPACT (NCT05001620)
- Testing
- Palliative Care Consultation
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Primary Health Care, Diabetes
Improvement of Diabetic Foot Care in Salamanca Through the Implementation of Standardized Protocols.
Introduction: Diabetic foot (DF) is among the most prevalent complications affecting individuals with diabetes. In Salamanca, 25,631 individuals are enrolled in the Diabetes Care Service, with only 3.06% undergoing a foot…
- Conditions
- Primary Health Care, Diabetes, Diabetic Foot
- Trial name
- NCT06250049
- Testing
- Diabetic foot care protocol, Group education sessions for patients and/or caregivers
- Where
- Spain
- Volunteers
- 25,631 people, healthy volunteers welcome
- Sponsor
- Sanidad de Castilla y León
Diabetes Mellitus, Hypertension
Strengthening Primary Healthcare Delivery for Diabetes and Hypertension in Eswatini
The WHO-PEN@Scale project is a three-arm cluster-randomized trial that is investigating the population-level effects of a healthcare reform in Eswatini, which aims to strengthen primary care for diabetes and hypertension.
- Trial name
- NCT04183413
- Testing
- DSD, CDP
- Where
- Eswatini
- Volunteers
- 3,500 people, healthy volunteers welcome
- Sponsor
- University Hospital Heidelberg
Dysautonomia, Anxiety
Implementation of Transdx Group for POTS
The proposed intervention is focused on developing and implementing a psychological approach incorporated into a group-based outpatient intervention for pediatric autonomic dysfunction.
- Conditions
- Dysautonomia, Anxiety, Depression
- Trial name
- NCT03185247
- Testing
- Transdiagnostic Group-Based Treatment
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Parenting Intervention, Maltreatment
Early Test of an Innovative Child Maltreatment (CM) Prevention Strategy
Millions of children are victims of maltreatment each year in the United States. Research on home visiting programs show that child maltreatment can be prevented; however, these programs struggle to reach families in need and…
- Conditions
- Parenting Intervention, Maltreatment, Prevention
- Trial name
- (CM) (NCT06912685)
- Testing
- Technology Enhanced Implementation Package, SafeCare
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Vaccines, Vaccines Adverse Reaction
A Multifaceted Intervention on Reducing Immunization Errors
The goal of this trial is to reduce the general error related to vaccines and immunizations (composited on secondary endpoint), after 11 moths of folow-up after cluster randomization and stepped wedge on primary care on brazilian…
- Conditions
- Vaccines, Vaccines Adverse Reaction, Vaccine Practice
- Trial name
- THEIA (NCT06745635)
- Testing
- Usual Care, Multifaceted intervention
- Where
- Brazil
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Hospital Israelita Albert Einstein
Health Knowledge, Attitudes, Practice
The Impact of Community Health Worker Training by US Health Volunteers on the Health of Rural Ugandans
There are many trials measuring the impact of service work on volunteers themselves, but few studies measuring the impact of service on the local people.
- Trial name
- NCT02045706
- Testing
- Community Health Worker Trainings
- Where
- 2 sites in United States, Uganda
- Volunteers
- 1,419 people, healthy volunteers welcome
- Sponsor
- Edward O'Neil Jr, M.D.
Cancer
Implementation of eHealth Delivery Alternatives for Cancer Genetic Testing for Hereditary Cancer (eREACH3)
The purpose of the study is to understand patient interest in telehealth and digital tools for pre-test genetic education and/or disclosure of genetic test results.
- Trial name
- eREACH3 (NCT07471958)
- Where
- United States
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Abramson Cancer Center at Penn Medicine
Colon Cancer
Reducing VA No-Shows: Evaluation of Predictive Overbooking Applied to Colonoscopy
In this research study, investigators use colonoscopy as a case example to evaluate a predictive overbooking model derived using patient-level predictors of absenteeism.
- Trial name
- No-show (NCT01639443)
- Testing
- Predictive no-show overbooking
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Primary Prevention
FIT FIRST Teen - School Intervention Study
The goal of this cluster randomised controlled trial is to investigate the effects of the FIT FIRST Teen program on adolescents' physical fitness, motivation, and well-being, as well as the implementation of such a program within…
- Trial name
- NCT06615791
- Testing
- FIT FIRST Teen
- Where
- Denmark
- Volunteers
- 912 people, healthy volunteers welcome
- Sponsor
- University of Southern Denmark
Colorectal Cancer (CRC) Screening
A Novel Multi-functional Artificial Intelligence System on Treatment Efficacy and Implementation in Colonoscopy
To overcome non-neoplastic polyp (NNP) resections, computer-aided diagnosis (CADx) systems have been developed. In a meta-analysis, the performance of CADx systems was superior to endoscopists.
- Trial name
- mAInstream (NCT07844252)
- Testing
- CADe/CADx
- Volunteers
- 2,818 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
DPYD Gene Mutation, Gastrointestinal Cancer
Nudge Strategies for DPYD Testing in Patients With Gastrointestinal Cancers Treated With Fluoropyrimidines
5-fluorouracil and capecitabine, sometimes called 5-FU, fluoropyrimidines, or Xeloda are a type of chemotherapy. Many people have side effects from these drugs like nausea, diarrhea, or blood problems.
- Conditions
- DPYD Gene Mutation, Gastrointestinal Cancer, Health Care Seeking Behavior
- Trial name
- DPYD Nudges (NCT06559462)
- Testing
- Focus Group, Discrete Choice
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Abramson Cancer Center at Penn Medicine
Smoking, Adolescent Behavior
ADHAirE : a Randomized Controlled Trial to Improve the Implementation of Tobacco-free School Policies
The goal of this cluster randomized controlled trial is to learn if the set up of an advocacy coalition in secondary schools can improve the implementation of tobacco-free school policies (TFSP) to prevent adolescent smoking.
- Trial name
- NCT06655038
- Testing
- Advocacy coalition, Feedback
- Where
- Belgium
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Université Catholique de Louvain