Clinical trials: Implant Therapy
Tooth Extraction Status Nos, Edentulous Alveolar Ridge
3D Radiographic Evaluation of a Novel Implant Site Development Technique
The present retrospective study aims at assessing the clinical effects of a novel implant site development (Extraction site development - XSD) technique after tooth extraction compared with extraction alone in patients requiring…
- Trial name
- NCT02660697
- Testing
- Extraction site development
- Where
- Hungary
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Semmelweis University
Periimplantitis, Periodontitis
Evaluation of the Effects of Routine Phase I Periodontal Therapy on Clinical Parameters and Levels of Gremlin-1, CTHRC1, and Tenascin-C in Gingival Crevicular Fluid and Peri-Implant Sulcular Fluid in Individuals With Periodontitis and Peri-Implantitis
The aim of this study is to compare the mechanisms of tissue destruction between natural teeth with periodontitis and implants with peri-implantitis within the same individual, and to evaluate the effects of routine Phase I…
- Trial name
- NCT07797127
- Testing
- Routine Phase I Non-Surgical Periodontal Therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Adiyaman University
Cataract
Evaluation the TECNIS IOL in Both Eyes VS the ReZoom IOL in One and TECNIS IOL in the Opposite
The purpose of this study is to evaluate the visual performance of two cohorts of patients who received multifocal intraocular lenses following cataract and clear lens extraction surgeries.
- Trial name
- NCT01253239
- Where
- United States
- Volunteers
- 175 people, healthy volunteers welcome
- Sponsor
- Frank A. Bucci, Jr., M.D.
Mucositis, Peri Implant Mucositis
Effects of Enamel Matrix Derivative in the Treatment of Peri-implant Mucositis
To evaluate the naturally occurring peri-implant mucositis (PM) treatment by means of non-surgical sub-marginal peri-implant instrumentation (NSPI) with or without use of enamel matrix protein derivative (EMD).
- Trial name
- NCT06725095
- Testing
- Enamel Matrix Proteins Derivative
- Where
- Italy
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- University of Catania
Health Care Utilization
A Pilot Study Efficiency of Techniques of 'Snail ' and 'Go-back' Application of an Alcoholic Antiseptic on Healthy Skin Before the Placement of a Intra-vascular Device,
Given the lack of scientific data on the effect of the antiseptic application technique on reducing the number of microorganisms present during application, this pilot study will provide data on the initial level of…
- Trial name
- TApAS (NCT04002245)
- Testing
- antiseptic application
- Where
- France
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bordeaux
Peri-Implant Marginal Bone Loss, Dental Implantation
CBCT Assessment of Marginal Bone Changes With Ozone Therapy
This study examined whether adding local gaseous ozone to standard dental implant treatment could reduce early bone loss around implants. Fifty adults requiring matched implants on opposite sides of the same jaw participated.
- Trial name
- ozone-ımplant (NCT07687641)
- Testing
- Gaseous Ozone Application, Conventional Implant Placement
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Adiyaman University
Women in Need of Long Acting Reversibel Cntraception With the Intrauterine Levonorgestrel Releasing System, Mirena
Pretreatment With Mifepristone Prior to Mirena Insertion
Hypothesis: Pretreatment with mifeprsitone prior to Mirena placement will induce amenorrhea and reduce bleeding irrregularities during the initial months of Mirena use.
- Trial name
- MiMi (NCT01931657)
- Testing
- Mifepristone prior to Mirena
- Where
- Sweden
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Edentulous
The Treatment of Implant-retained Mandibular Overdentures for Edentulous Patients
The purpose of this study is to investigate to what extent IOs improve the functionality of edentulous patients and changes in quality of life and overall patient satisfaction following treatment with IOs.
- Trial name
- TIMOEP (NCT02846805)
- Testing
- implant-retained overdentures
- Where
- China
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Chufan Ma
Photobiomodulation Therapy
Photobiomodulation and Implant Stability
Objective: The aim of the present study was to address the following questions: does photobiomodulation therapy (PBMT) improve implant stability and affect microbiota around dental implants in the early stage of osseointegration.
- Trial name
- low-laser (NCT04495335)
- Testing
- photobiomodulation
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- T.C. Dumlupınar Üniversitesi
TMJ, Apical Periodontitis
Application of a Dental-dedicated MRI in the Diagnosis of Temporomandibular Joint Disorders, Tissue Alterations Related to Third Molars, Periapical and Periodontal Inflammatory Diseases, and Implant Treatment Planning
The aim of the present study is to show that the use of 0.55T MRI combined with a "dental" coil produces images of sufficient diagnostic value to assess areas of interest in dentistry, and to compare MR images to traditional…
- Conditions
- TMJ, Apical Periodontitis, Periodontal Inflammation, Retained Tooth
- Trial name
- NCT05439330
- Testing
- MRI of teeth and surrounding structures
- Where
- Denmark
- Volunteers
- 470 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Dental Implant, Bruxism
The General Aim is to Implement Clinical Assessment of Overload by Voluntary Bite Force Registration to Enable Future Simple But Precise Risk Assessment to Provide Individualized Treatment Plans.
The general aim of this clinical trial is to implement clinical assessment of overload by bite force registration to enable future simple but precise risk assessment to provide individualized treatment plans.
- Conditions
- Dental Implant, Bruxism, Bite Force, Dental Prosthesis Complication
- Trial name
- Bite force (NCT07266701)
- Testing
- Bite force device. Innobyte Kube Innovation TM, dental radiology
- Where
- Sweden
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Malmö University
Implant Complication, Periimplant Infection
The Effect Of Photobiomodulation On Dental Implant Survival
Dental implants offer a high success rate as the most up-to-date treatment method for replacing lost teeth. However, whilst implants have emerged as the ideal treatment for tooth loss, the incidence of postoperative…
- Conditions
- Implant Complication, Periimplant Infection, Periimplant Bone Loss
- Trial name
- NCT07636265
- Testing
- photobiomodulation
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Nigde Omer Halisdemir University
Cervical Degenerative Disc Disease
Dynamic Cervical Implant (DCI) Versus Anterior Cervical Discectomy And Fusion(ACDF) For The Treatment Of Single-Level Cervical Degenerative Disc Disease (DDD): An RCT
TO Compare The Clinical And Radiographic Outcomes of DCI VS ACDF For The Treatment Of Single-Level Cervical Degenerative Disc Disease (DDD)
- Trial name
- NCT05522010
- Testing
- Cervical spine surgery
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Assiut University
Root Caries
Evaluation of Corrective Surgery Versus Dental Implants in Compromised Upper Molars
This study seeks to assess the clinical, radiographic, and patient-reported outcomes of root amputation versus implant over a 12 months period, generating robust evidence to guide clinical decision-making and enhance patient care.
- Trial name
- NCT07608497
- Testing
- root amputation
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Retinal Vein Occlusion (RVO), Macular Edema
Ozurdex Implant for Macular Edema After Treatment Failure With Anti-VEGF
To determine if Ozurdex implant can offer an effective treatment for macular edema associated with retinal vein occlusion when treatment with intravitreal Avastin, Lucentis, or Eylea have not demonstrated a significant response.
- Trial name
- NCT01946399
- Testing
- Ozurdex implant
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Retina Research Institute, LLC
Implant, Peri-Implantitis
Efficacy of Diode Laser in Peri-implantitis
The aim of this study was to compare the efficacy of a diode laser (DL) as an adjunct to conventional scaling in the treatment of mild-to-moderate peri-implantitis.
- Conditions
- Implant, Peri-Implantitis, Alveolar Bone Loss, Complications
- Trial name
- NCT02362854
- Testing
- Conventional peri-implantitis treatment, DL application in peri-implantitis
- Where
- Turkey (Türkiye)
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Postoperative Pain
Efficacy of EXPAREL in Comparison to Standard of Care for the Treatment of Post Operative Dental Implant Pain
This study is researching managing postsurgical pain by injecting both short-acting local anesthetics and EXPAREL® at the time of surgery and reviewing if it could reduce or eliminate the need for postsurgical opioids and improve…
- Trial name
- FAST (NCT02533440)
- Testing
- EXPAREL and Local Anesthetics, Oral Opioid and Local Anesthetics
- Where
- 3 sites in United States
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Bellaire Facial Surgery Center
Patient Satisfaction
Evaluation of Masticatory Performance and Patient Satisfaction for Conventional and 3D Printed Implant Overdentures
The aim of this crossover clinical study was the evaluation and comparison of masticatory performance and patient satisfaction for patients rehabilitated with conventional heat cured acrylic resin and 3D printed mandibular…
- Trial name
- NCT06148727
- Testing
- Dental implant placement, Bar attachment
- Where
- Egypt
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Postoperative Wound Infection Deep Incisional Surgical Site, Prosthesis and Implants
Effect of Photodynamic Treatment on Skin Microbiome. Single Center Study
The overarching aim of this research project is to prevent orthopedic implant-associated infections. This study aims to investigate if photodynamic therapy has an effect on bacterial skin colonization and decrease number of…
- Conditions
- Postoperative Wound Infection Deep Incisional Surgical Site, Prosthesis and Implants, Surgical Site Infection, Prosthetic Joint Infection
- Trial name
- PHOMIC (NCT04067843)
- Testing
- Photodynamic treatment
- Where
- Switzerland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Tooth Loss in the Anterior Maxilla, Alveolar Bone Resorption
Peri-Implant Hard and Soft Tissue Changes After Immediate Implant Placement With Socket Shield and Immediate Restoration Versus Early Implant Placement in the Esthetic Zone
This randomized controlled clinical trial aims to compare peri-implant hard and soft tissue dimensional changes following immediate implant placement with the socket shield technique and immediate restoration versus early type II…
- Conditions
- Tooth Loss in the Anterior Maxilla, Alveolar Bone Resorption, Partial Edentulism of the Maxilla
- Trial name
- NCT07468760
- Testing
- Socket Shield, Early Implant Placement
- Where
- United Arab Emirates
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Gulf Medical University