Clinical trials: Impacted Third Molar Tooth
Teeth, Impacted
Bupivacaine in the Treatment of Postoperative Pain of Impacted Third Molar Extraction
The third molars are the teeth that are most frequently included and impacted, extraction is one of the most performed treatments by maxillofacial surgeons in their clinical practice.
- Trial name
- NCT03950700
- Testing
- Bupivacaine-epinephrine, Saline Solution
- Where
- Colombia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- CES University
Tooth, Impacted, Wound Heal
Effect of Low Level Laser Therapy After Wisdom Tooth Removal
The aim is to test the effect of low level laser therapy on the relief of symptoms after wisdom tooth removal.
- Conditions
- Tooth, Impacted, Wound Heal, Quality of Life
- Trial name
- NCT04437316
- Testing
- Use of Low level Laser after wisdom tooth removal
- Where
- Switzerland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Impacted Lower Third Molar, Alveolar Bone Regeneration Following Odontectomy
Evaluating The Use of CGF Made Gel in Mandibular Extraction Sites of Lower Impacted 3rd Molars.
The goal of this clinical trial is to learn if Concentrated Growth Factor (CGF) Gel help improve bone healing and reduce pain after the surgical removal of impacted lower third molars.
- Conditions
- Impacted Lower Third Molar, Alveolar Bone Regeneration Following Odontectomy, Postoperative Pain Management in Oral Surgery, Concentrated Growth Factor for Extraction Socket Healing
- Trial name
- CGF (NCT07520097)
- Testing
- Concentrated Growth Factor (CGF) Gel
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Cairo University
Post Operative Pain, Impacted Third Molar Tooth
Jaw Muscle Pain Post Wisdom Molar Surgery
The proposed design is a triple-blind, placebo-controlled randomized prospective phase II trial to assess the feasibility of employing the Temporo-masseteric Nerve Block (TMNB) injection to decrease jaw muscle pain, overall pain…
- Conditions
- Post Operative Pain, Impacted Third Molar Tooth, Muscle Pain
- Trial name
- NCT07094542
- Testing
- Temporo-masseteric Nerve Block Injection, Oral Pain Medications only
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Rutgers, The State University of New Jersey
Molar, Third, Surgery, Oral
Comparison of Computer-Assisted and Conventional Local Anesthesia Methods in Mandibular Impacted Third Molar Surgery
The goal of this clinical trial is to evaluate the effects of computer-assisted local anesthesia and conventional local anesthesia on pain perception and dental anxiety during inferior alveolar block anesthesia in impacted…
- Conditions
- Molar, Third, Surgery, Oral, Anxiety, Local Anesthesia
- Trial name
- NCT06852066
- Testing
- Computer-Assisted Local Anesthesia, Conventional Local Anesthesia
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Afyonkarahisar Health Sciences University
Acute Pain, Postoperative Pain
Efficacy and Safety of Etoricoxib-tramadol Tablet in Acute Postoperative Pain
The goal of the present phase IIb clinical trial was to compare the safety and efficacy of the fixed-dose combination etoricoxib-tramadol 120mg/100mg tablet (once a day, for three days) versus naproxen 220mg tablet plus tramadol…
- Trial name
- NCT05995912
- Testing
- etoricoxib-tramadol, Naproxen, Tramadol
- Where
- Mexico
- Volunteers
- 58 people
- Sponsor
- Laboratorios Liomont
Pain, Postoperative
Preemptive Analgesia With Celecoxib for Acute Dental Pain Management
The purpose of this study is to compare the effect on postoperative pain of a single agent nonsteroidal anti-inflammatory drug (NSAID) [celecoxib plus placebo] to an NSAID combination [celecoxib plus acetaminophen] administered…
- Trial name
- NCT04790812
- Testing
- Celecoxib, Acetaminophen
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
Impacted Mandibular Third Molar
Comparison of Chlorhexidine and Hypochlorous Acid Mouthwash After Impacted Third Molar Surgery
Impacted mandibular third molar extraction is one of the most common procedures in oral and maxillofacial surgery and is frequently associated with postoperative complications such as pain, edema, and trismus, which may…
- Trial name
- NCT07466992
- Testing
- Hypochlorous Acid, Chlorhexidine Gluconate Mouthwash
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Yuzuncu Yil University
Impacted Third Molar Tooth
Effect of St. John's Wort and Olive Oils on the Postoperative Complications
Surgical removal of impacted third molars is one of the most frequent procedures carried out in the oral and maxillofacial surgery clinics.
- Trial name
- NCT04373421
- Testing
- Chlorhexidine Gluconate 0.12 % Mouthwash + benzydamine hydrochloride, St. John's wort oil, Virgin olive oil
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Yuzuncu Yil University
Impacted Mandibular Third Molar, Postoperative Pain
Effect of Platelet-Rich Fibrin on Postoperative Pain, Trismus, and Edema After Mandibular Third Molar Surgery
Impacted mandibular third molars are among the most commonly encountered conditions in oral and maxillofacial surgery. Surgical removal of these teeth is frequently associated with postoperative complications such as pain, facial…
- Conditions
- Impacted Mandibular Third Molar, Postoperative Pain, Trismus, Edema Face
- Trial name
- PRF-M3M (NCT07672951)
- Testing
- Platelet-rich fibrin (PRF), Sterile Absorbable Gelatin Sponge
- Where
- Pakistan
- Volunteers
- 134 people
- Sponsor
- PAEC General Hospital, Islamabad
Oral Complication
Effect of CGF on Postoperative Edema in Third Molar Surgery
The purpose of this study is to evaluate the effects of concentrated growth factor (CGF) on edema after bilateral impacted third molar surgery and to determine its contribution to the healing process.
- Trial name
- NCT06893523
- Testing
- Concentrated Growth Factor, Non-CGF
- Where
- Turkey (Türkiye)
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Ege University
Third Molar Extraction, Piezoelectric Technique
Piezoelectric and Conventional Rotary Techniques in Third Molar Surgery: Postoperative Outcomes and Quality of Life
This study is a prospective, randomized clinical trial comparing recovery after the surgical removal of impacted lower wisdom teeth. The aim is to evaluate swelling, pain, mouth opening, and quality of life after surgery.
- Trial name
- NCT07185620
- Testing
- Third molar surgery with piezoelectric system, Third molar surgery with Conventional Rotary System
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Izzet Acikan
Impacted Mandibular Third Molar, Edema
Single-Session Extraoral PBM After Third Molar Extraction
Postoperative pain, edema, and trismus are frequent complications following impacted mandibular third molar surgery. This randomized controlled trial evaluated the effects of a single-session extraoral dual-wavelength…
- Conditions
- Impacted Mandibular Third Molar, Edema, Trismus, Postoperative Pain
- Trial name
- NCT07522918
- Testing
- Dual-wavelength GaAlAs laser (650+904 nm)
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Konya Necmettin Erbakan Üniversitesi
Alveolar Osteitis
The Effect of Post-extraction Collagen Sponge Application on Alveolar Osteitis
The goal of this randomized controlled trial is to compare pain, mouth opening, and alveolar osteitis following surgical extraction of bilateral symmetrical impacted lower third molars using two types of wound closures.
- Trial name
- NCT05850650
- Testing
- Application of a collagen sponge after surgical extraction of impacted 3rd molar, No collagen sponge application after surgical extraction of impacted 3rd molar
- Where
- Saudi Arabia
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Riyadh Colleges of Dentistry and Pharmacy
Impact Molar, Mandible Cyst
Bone Defects Reconstruction After Dentigerous Cyst Enucleation With Autogenous Demineralized Dentin Matrix- ADDM and Advanced Platelet-Rich Fibrin- A-PRF.
This prospective clinical study evaluates bone healing following dentigerous cyst enucleation associated with impacted mandibular third molar extraction.
- Conditions
- Impact Molar, Mandible Cyst, Bone Regeneration, Platelet Rich Fibrin
- Trial name
- Cystregen (NCT07652216)
- Testing
- Impacted third molar extraction, Advanced Platelet-Rich Fibrin (A-PRF), Mandibular dentigerous cyst enucleation
- Where
- Poland
- Volunteers
- 35 people
- Sponsor
- Jagiellonian University
Melatonin
Effects of Melatonin and Massage After Third Molar Surgery
Lymphatic drainage massage is an important practice, especially for reducing edema. It is a very gentle, monotonous, slow, rhythmic massage applied to the skin surface.
- Trial name
- NCT06812026
- Testing
- no melatonin and massage, receive melatonin, receiving lymphatic drainage
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
To Control Pain After Third Molar Surgery
Efficacy of Preoperative Administration of Paracetamol-codeine on Pain Following Impacted Mandibular Third Molar Surgery
Objectives: The aim of this study was to determine the effectiveness of preoperative administration of single-dose of paracetamol-codeine, in the relieving of acute post-operative pain after the surgical removal of an impacted…
- Trial name
- NCT03049878
- Testing
- Paracetamol Codeine
- Volunteers
- 32 people
- Sponsor
- University of Roma La Sapienza
Facial Swelling, Pain
Effects of Low-level Laser Therapy After Surgical Removal of Impacted Lower Third Molar
Goal: The aim of this study was to evaluate the effects of low-level laser (LLL) after surgical removal of impacted lower third molars (ILTM).
- Conditions
- Facial Swelling, Pain, Trismus
- Trial name
- NCT04280809
- Testing
- GaAlAs laser
- Where
- Vietnam
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Pain, Edema
Evaluation of Two Pharmacological Protocols for Pre-emptive Analgesia in Impacted Third Molar Surgery
The main aim of the study is to investigate the pre-emptive effect of dexamethasone and diclofenac associated to codeine to prevent the pain, edema and limited mouth opening at the extraction of third molar.
- Conditions
- Pain, Edema, Trismus
- Trial name
- NCT02665533
- Testing
- Dexamethasone, Diclofenac Sodium associated with Codeine
- Where
- Brazil
- Volunteers
- 18 people
- Sponsor
- Federal University of the Valleys of Jequitinhonha and Mucuri
Platelet-Rich Fibrin (PRF), Impacted Mandibular Third Molar
Salivary α-Amylase as a Non-Invasive Biomarker of PRF-Enhanced Wound Healing After Third Molar Surgery
This randomized clinical study evaluated salivary α-amylase as a non-invasive biomarker of early wound healing after mandibular third molar surgery.
- Conditions
- Platelet-Rich Fibrin (PRF), Impacted Mandibular Third Molar, Postoperative Wound Healing, Salivary Alpha Amylase
- Trial name
- NCT07600619
- Testing
- PRF group
- Where
- Indonesia
- Volunteers
- 28 people
- Sponsor
- Hasanuddin University