Clinical trials: Immobilization
Distal Radius Fracture
Short Forearm Casting Versus Below-elbow Splinting for Acute Immobilization of Distal Radius Fractures
There is no consensus regarding the need to immobilize the elbow in immediate immobilization of closed distal radius fractures post-reduction.
- Trial name
- NCT02679066
- Testing
- Sugar-tong splint, Short forearm cast
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Disuse Atrophy, Aging
Immobilization and Protein Supplementation (IM-PRO)
In the present study, the effects of 5 days of lower limb immobilization with or without twice-daily protein supplementation on muscle mass and muscle fiber characteristics will be determined.
- Trial name
- IM-PRO (NCT01588808)
- Testing
- Immobilization
- Where
- Netherlands
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Hand Osteoarthritis
Effect of Immobilization of the Metacarpophalangeal Joint in Thumb Osteoarthritis
The aim of this study is to compare the effect of Whale and Colditz static orthosis on pain and functional abilities of hand in thumb carpometacarpal osteoarthritis as a unique treatment.
- Trial name
- NCT02780999
- Testing
- Whale orthosis, Colditz orthosis
- Where
- Spain
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- University of Malaga
Healthy Subjects, Patients With Amyotrophic Lateral Sclerosis, Patients With Shoulder Surgery
Neurofeedback Rehabilitation Based on Motor Imaging in Patients in the Immobilization Phase
As the prevalence of motor impairment increases with age, the proportion of the population affected by physical limitations is likely to increase in the coming years, considering that one in three people will be over 60 in 2050…
- Trial name
- REMINARY (NCT03545451)
- Testing
- Videogames
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Cervical Vertebra Injury, Cervical Vertebra Fracture
Three Instructional Interventions for Prehospital Cervical Spinal Immobilization by Laypeople
It is not known if bystanders equipped with point-of-care (POC) instruction are as effective as bystanders with in-person training for c-spine immobilization.
- Trial name
- NCT05359575
- Testing
- Audio kit, Instructional flashcard (version 1), In-person training
- Where
- United States
- Volunteers
- 265 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Distal Radius Fractures
Immobilization of Postoperative Distal Radius Fractures
The management of distal radius fractures has been in a state of evolution over the past 30 years. Treatment has become increasingly focused on obtaining a stable, internal construct for quick return to normal, daily activities.
- Trial name
- NCT02802774
- Testing
- Plaster Splint, Velcro Brace, Soft Dressing
- Where
- 2 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Restless Leg Syndrome
The Suggested Immobilization Test With Exploratory Heart Rate Variability Analysis for Diagnosis of Restless Legs Syndrome
Restless leg syndrome (RLS) is not uncommon and can also affect people's health and quality of life. Mainly, RLS is diagnosed based on clinical criteria subjectively.
- Trial name
- NCT07110961
- Testing
- A suggested immobilization test (SIT)
- Where
- Thailand
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Siriraj Hospital
Endotracheal Intubation
Intubation During Spinal Immobilization
The aim was to evaluate the performance of the C-MAC compared with Macintosh when performed in patients with immobilized cervical spine by unexperienced physicians.
- Trial name
- NCT02733536
- Testing
- Standard endotracheal tube, C-MAC
- Where
- Poland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Medical University of Warsaw
Healthy
A Study of the Effect of BIIB023 on Muscle Atrophy in Healthy Male Volunteers
The primary objective of this study is to determine whether muscle atrophy induced by immobilization of the lower limb can be attenuated by BIIB023 in healthy male volunteers.
- Trial name
- NCT01943513
- Testing
- BIIB023
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Biogen
Weakness, Muscle, Muscle Weakness
Short Term Immobilization of the Lower Limb
The purpose of this study is to determine the effects of one week of knee-joint immobilization on muscle size, strength, neuromuscular function, and brain function.
- Conditions
- Weakness, Muscle, Muscle Weakness, Muscle Loss, Muscle Atrophy
- Trial name
- STILL (NCT05072652)
- Testing
- Neuromuscular Electrical Stimulation, Action Observation + Mental Imagery
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Central Florida
Healthy
Forearm Immobilization, Metabolic Health, and Nutrition
The present study will investigate the impact of dietary branched chain amino acid restriction on muscle atrophy, insulin sensitivity and muscle protein synthesis following short-term forearm immobilization
- Trial name
- NCT04626401
- Testing
- Forearm immobilization
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Exeter
Massage Therapy, Muscular Atrophy
Effect of Percussive Massage on Skeletal Muscle During Limb Immobilization
The primary aims of this study are to determine the effect of percussive massage (30 min/session, 2 sessions/day, daily) during 10 days of unilateral limb immobilization on preserving muscle, vascular, and mitochondrial function.
- Trial name
- NCT06053229
- Testing
- percussive massage, Leg Immobilization
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Brigham Young University
Hot Weather; Adverse Effect, Immobilization, Tonic
Heat Therapy to Prevent Deconditioning During Immobilization
Animal models suggest that heat stress increases protein content and facilitates the recovery of atrophied muscle after an immobilization period, or following a chemically induced muscle injury in rats.
- Trial name
- NCT05021523
- Testing
- Hot ambient conditions exposures, Immobilization
- Where
- Qatar
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Aspetar
Immobilization, Physical Inactivity
Effects of Unloading on Muscle Mass
In the present study, the effects of 3 weeks of unloading on muscle mass and muscle fiber characteristics will be determined. In addition, the effects of 6 weeks of recovery will be assessed.
- Trial name
- NCT00936039
- Testing
- unloading
- Where
- Netherlands
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Immobilization, Tonic, Physical Activity
Vascular Health With Immobilization and Exercise Training
The study includes healthy young habitually active subjects. All subjects are subjected to two weeks of immobilization of one leg followed by four weeks of training of both legs.
- Trial name
- NCT03054376
- Testing
- Immobilization, Training with non immobilized leg, Exercise training with both legs
- Where
- Denmark
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Copenhagen
Bone Diseases, Metabolic, Acid-Base Imbalance
The Effect of Potassium Bicarbonate on Bone and Several Physiological Systems During Immobilisation
Mainly due to the absence of gravitational forces in weightlessness, astronauts suffer from an increased bone loss- negatively affecting health and vitality during a mission.
- Conditions
- Bone Diseases, Metabolic, Acid-Base Imbalance, Muscular Atrophy, Sprains and Strains
- Trial name
- NUC (NCT01509456)
- Testing
- Potassium Bicarbonate
- Where
- Germany
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- DLR German Aerospace Center
Healthy
The Effects of Immobilisation and Exercise on Homeostatic Plasticity Mechanisms in Healthy Participants
Homeostasis is important for maintaining a stable equilibrium of e.g., blood pressure, hormonal release, and release of neurotransmitters.
- Trial name
- NCT05252247
- Testing
- Immobilisation, Exercise
- Where
- Denmark
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Aalborg University
Muscle Atrophy
The Effects of 17β-estradiol on Skeletal Muscle
The maintenance of skeletal muscle mass and function is critical for healthy aging. Muscle loss with disuse, termed muscle disuse muscle atrophy, leads to impaired functional capacity, the onset of insulin resistance, as well as…
- Trial name
- NCT03069781
- Testing
- 17β-estradiol, Polycose
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- McMaster University
Spinal Fractures
Anterior Screw Fixation Versus Halo Immobilization of Type II Odontoid Fractures in Geriatric Patients With Increased Anesthesia Risk
The management of type II odontoid fractures in geriatric trauma victims remains a source of substantial controversy. The purpose of this study was to compare anterior screw fixation with halo-vest-immobilization in patients with…
- Trial name
- NCT02432495
- Testing
- ANTERIOR SCREW FIXATION, HALOV VEST IMMOBILIZATION
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Healthy Volunteer, Atrophy, Muscular
A Clinical Study to Assess the Effects of SRT2104 Upon Immobilization-Induced Skeletal Muscle Atrophy in Healthy Human Volunteers
The main purpose of this study is to investigate the effect of SRT2104 upon energy production in muscle (specifically the maximum amount of energy produced with muscle contraction), how much sugar and fat are stored in the…
- Trial name
- NCT01039909
- Testing
- SRT2104
- Volunteers
- healthy volunteers welcome
- Sponsor
- GlaxoSmithKline