Clinical trials: Imaging Evaluation
Gynecologic Surgery
A Study of Near-Infrared Fluorescence Imaging With ICG During Reconstructive Gynecologic Surgery
The objective of this study is to assess whether Near-Infrared Fluorescence/NIR Imaging perfusion alters intraoperative management of the flap or of the participant wound bed.
- Trial name
- NCT05071976
- Testing
- ICG-NIR angiography
- Where
- 7 sites in United States
- Volunteers
- 15 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Rectal Cancer
Rectal Cancer: Local Staging, Re-staging and Assessment of Lymph Nodes Using Pet-Ct, CT-Perfusion and 3T MRI
The purpose of this study is to evaluate the accuracy of Positron emission tomography, Computed Tomography perfusion and 3 Tesla MRI in the radiological down-staging of rectal cancer following neoadjuvant chemoradiation.
- Trial name
- NCT01525056
- Testing
- ct and mri scans, ct, mri and pet scan, ct, mri and pet scans
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- London Health Sciences Centre
Stroke, Neglect, Hemispatial
Motor Imaging, Neglect, and Upper Extremity Function in Stroke
This study aims to investigate the relationship between motor imagery skills and neglect level, upper extremity motor function, activities of daily living, quality of life, lateralization performance, and mental timer performance…
- Conditions
- Stroke, Neglect, Hemispatial, Motor ımargery, Upper Extremity Function
- Trial name
- NCT07480122
- Testing
- No intervention will be made; an assessment will be conducted.
- Volunteers
- 50 people
- Sponsor
- Inonu University
Endometriosis
Evaluation of Endometriosis With 18F-fluorofuranylnorprogesterone PET / MRI
Purpose: The aim of this study is to assess the sensitivity and specificity of FFNP PET/MRI for diagnosis of endometriosis. Participants: A total of 24 participants will be recruited from individuals with clinically suspected…
- Trial name
- NCT05480995
- Testing
- 18F-fluorofuranylnorprogesterone PET / MRI
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- University of North Carolina, Chapel Hill
Eating Disorders, Eating Behavior
Food Reward Circuit Change by Orthodontics
It has been described in obese individuals in which decreased basal metabolism as well as dopaminergic changes in the prefrontal cortex and striatum parallels the increased activation of reward brain regions in response to…
- Conditions
- Eating Disorders, Eating Behavior, Eating Habit, Orthodontic Appliance Complication
- Trial name
- DTI (NCT05026411)
- Testing
- T 0 Diffusion Tensor MR, T 1 Diffusion Tensor MR, T 2 Diffusion Tensor MR
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Lung Inflammation
Evaluation of Rosiglitazone Anti-inflammatory Effect With FDG-PET Imaging
The purpose of this research study is to gain understanding of the basic responses of the lung to inflammation and specifically if a certain medication can reduce the inflammation alone or in combination with another.
- Trial name
- NCT01174056
- Testing
- Zileuton, Pioglitazone
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Depression
TMS Treatment for Depression in the National Health Service
This research programme purports to test the effectiveness of two Transcranial Magnetic Stimulation (TMS) protocols (Repetitive high frequency protocol and Theta Burst protocol) in reducing the symptoms of depression.
- Trial name
- TDEP (NCT02016456)
- Testing
- Theta-Burst Stimulation, High frequency stimulation
- Where
- United Kingdom
- Volunteers
- 29 people
- Sponsor
- Institute of Mental Health Nottingham
Malignant Brain Tumors
(68^Ga)-GaPSMA-11 PET/MR-imaging of Malignant Intra-axial Brain Tumors
PSMA is a transmembrane protein specifically expressed in the vascular endothelium of malignant brain tumors, most notably glioblastoma and not in healthy brain parenchyma.
- Trial name
- NCT05798273
- Testing
- intra-arterial injection, synchronous PET/MRI scan, Radiopharmacon Contrast agent
- Where
- Netherlands
- Volunteers
- 12 people
- Sponsor
- Erasmus Medical Center
Cellulite, Gynoid Lipodystrophy
Quantitative Assessment of the Efficacy of Alidya
This study evaluated the efficacy of ALIDYA, a Class III medical device used in needle mesotherapy, for the treatment of cellulite (gynoid lipodystrophy) in women.
- Trial name
- NCT07675356
- Testing
- ALIDYA
- Where
- 2 sites in Poland
- Volunteers
- 30 people
- Sponsor
- Medical University of Silesia
Low Back Pain
Biomechanics of Lumbar Region in Low Back Pain
The purpose of this study was to examine the relationship between non-specific low back pain (NSLBP) and lumbar lordosis angle (LLA) and lumbar muscle thickness (LMT) by evaluating magnetic resonance images (MRI) in individuals…
- Trial name
- NCT05095402
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people
- Sponsor
- Karabuk University
Diastolic Dysfunction, Neonatal Encephalopathy
Assessment of Diastolic Function During the Transitional Period and Infancy Using Serial Echocardiography
The goal of this single-centre longitudinal observational study is to create reference values for diastolic function parameters in neonates born at 35 weeks' gestation or above, and to assess the influence of pre-defined…
- Conditions
- Diastolic Dysfunction, Neonatal Encephalopathy, Small for Gestational Age at Delivery, Transient Tachypnea of the Newborn
- Trial name
- DiFuSE (NCT06200519)
- Where
- Ireland
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- University College Cork
Living Renal Donor
Living Renal Donor MRI Study
Accurate preoperative evaluation of a potential living renal donor's anatomy, vasculature and function is crucial to ensure optimal outcomes for both kidney donor and recipient in transplantation.
- Trial name
- NCT01280851
- Testing
- Magnetic Resonance Imaging
- Sponsor
- University Health Network, Toronto
Liver Transplantation, MRI
Exploring the Application Value of New Magnetic Resonance Imaging Technologies in Non-invasive Quantitative Assessment of Graft Function After Liver Transplantation
Title: Exploring the Application Value of New Magnetic Resonance Imaging Technologies in Non-invasive Quantitative Assessment of Graft Function after Liver Transplantation Purpose of the Study: This study aims to investigate the…
- Conditions
- Liver Transplantation, MRI, Graft Function
- Trial name
- NCT06994429
- Testing
- MRI Techniques for Graft Function Assessment
- Where
- China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Zhen Li
Osteoarthritis, Knee
Assess the Blood-Oxygen-Level-Dependent (BOLD) Signal Changes in the Brain by Paracetamol as Measured by Functional Magnetic Resonance Imaging (fMRI) in Subjects With Osteoarthritis (OA)
Blood-Oxygen-Level-Dependent (BOLD) responses to painful mechanical stimulation of the OA knee following treatment with four consecutive doses (at 8 hour intervals) on giving sustained released paracetamol treatment or placebo…
- Trial name
- NCT01105936
- Testing
- Paracetamol
- Where
- Spain
- Volunteers
- 31 people
- Sponsor
- GlaxoSmithKline
Stress Induced Cardiomyopathy
Pathogenesis of Stress-Induced Cardiomyopathy by I-123 MIBG
Objective: The objective of this pilot study is to characterize the cardiac uptake patterns of I-123 mIBG in stress-induced (Takotsubo's) cardiomyopathy.
- Trial name
- NCT01432626
- Testing
- I-123 radiolabeled metaiodobenzylguanidine cardiac imaging
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Pittsburgh
Hemoglobinopathies, Myelodysplastic Syndromes
Magnetic Resonance Imaging (MRI) Assessments of the Heart and Liver Iron Load in Patients With Transfusion Induced Iron Overload
This study will evaluate the change in cardiac iron load over a 53 week period measured by MRI in 2 cohorts of patients
- Conditions
- Hemoglobinopathies, Myelodysplastic Syndromes, Other Inherited or Acquired Anaemia, MPD Syndrome
- Trial name
- NCT00673608
- Testing
- deferasirox
- Where
- 4 sites in Australia
- Volunteers
- 118 people
- Sponsor
- Novartis
Malignant Skin Neoplasm, Skin Disorder
Optical Imaging Scans for the Diagnosis of Skin Cancer in Patients With Lesions
This clinical trial studies how well an optical imaging scan called quantitative oblique back-illumination microscopy (qOBM) helps in diagnosing skin cancer in patients with skin lesions.
- Conditions
- Malignant Skin Neoplasm, Skin Disorder, Skin Neoplasm
- Trial name
- NCT07213154
- Testing
- Quantitative Oblique Back-Illumination Microscopy, Radiation Therapy
- Where
- 2 sites in United States
- Volunteers
- 10 people
- Sponsor
- Emory University
Polyarthritis
Erosive Osteoarthritis of the Hands: Treatment by Methotrexate Versus Placebo
Interest of methotrexate in inflammatory rheumatisms was demonstrated since several years. At present time,there is no effective treatment against digital arthritis.
- Trial name
- ADEM (NCT01068405)
- Testing
- Methotrexate
- Where
- France
- Volunteers
- 64 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Non-small Cell Lung Cancer
Macrophage Imaging Using Ga-MMR-VHH2 in Lung Cancer Patients
Phase II study to evaluate the clinical potential of 68GaNOTA-anti-MMR-VHH2 for in vivo imaging of Macrophage Mannose Receptor (MMR)-expressing Macrophages by means of Positron Emission Tomography (PET) in patients with non-small…
- Trial name
- MAGMA (NCT05933239)
- Testing
- 68GaNOTA-Anti-MMR-VHH2
- Where
- Belgium
- Volunteers
- 20 people
- Sponsor
- Universitair Ziekenhuis Brussel
Urothelial Carcinoma (UC), HER2
Artificial Intelligence-assisted HER2 Expression Assessment in Urothelial Carcinoma Based on Imaging-pathology Omics
This study aims to build upon previous research by using artificial intelligence methods to fuse multimodal data from imaging and pathology to construct a predictive model for HER2 expression in urothelial carcinoma.
- Conditions
- Urothelial Carcinoma (UC), HER2, Diagnostic
- Trial name
- NCT07454941
- Where
- China
- Volunteers
- 4,000 people
- Sponsor
- Cancer Institute and Hospital, Chinese Academy of Medical Sciences