Clinical trials: Imaging Evaluation
Alzheimer Disease
Illiteracy and Vulnerability to Alzheimer's Disease: Evaluation of Amyloid Pathology by PET Imaging
The goal of this study is to improve the diagnosis of Alzheimer's disease (AD) at two different stages (MCI and dementia) in illiterate subjects, using FDG- fluorodeoxyglucose - and florbetapir F 18 -PET imaging.
- Trial name
- AVILL (NCT02494531)
- Testing
- Fluorodeoxyglucose-PET, florbetapir F 18-PET
- Where
- France
- Volunteers
- 45 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Hyperhidrosis
Histological Analysis Following Ulthera System Treatment for Hyperhidrosis
Up to 60 subjects will be enrolled into one of five treatment groups. Subjects enrolled in Groups A, B or C will undergo axillary punch biopsies during the course of the trial to determine the number and depth of the sweat…
- Trial name
- NCT01708551
- Testing
- Ulthera System Treatment
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- Ulthera, Inc
Peritoneal Carcinomatosis
A Study to Evaluate ONM100, an Intraoperative Fluor Imaging Agent for the Detection of Peri Mets
Peritoneal carcinomatosis (PC) results from the metastasis of a primary cancer of the peritoneum (e.g., appendiceal, ovarian, uterine, colorectal, and gastric cancers) that then disseminates throughout the abdominal cavity.
- Trial name
- NCT04950166
- Testing
- pegsitacianine
- Where
- 5 sites in United States
- Volunteers
- 51 people
- Sponsor
- OncoNano Medicine, Inc.
Peripheral Arterial Disease
Evaluation of the Pantheris Atherectomy System
A non-randomized, prospective, global clinical trial of the Avinger Pantheris System, an atherectomy device that provides directional visualization and imaging as an adjunct to fluoroscopy to aid removal of plaque in diseased…
- Trial name
- VISION (NCT01937351)
- Testing
- Pantheris System
- Where
- 21 sites in United States, Germany
- Volunteers
- 162 people
- Sponsor
- Avinger, Inc.
Patients With a Sonographically Unclassifiable Adnexal Mass Using the IOTA Simple Rules
Value of MRI in the Characterization of Ovarian Masses Unable to Classify With Ultrasound Using the International Ovarian Tumor Analysis (IOTA) Simple Rules
Gynecological ultrasound is well known as the preferred exam to assess patients with ovarian tumors. The International Ovarian Tumor Analysis (IOTA) group developed the 'Simple Rules' to classify an ovarian tumor as benign or…
- Trial name
- IOTA-MRI (NCT02836275)
- Testing
- Diffusion/Perfusion-weighted Magnetic Resonance Imaging
- Where
- Belgium
- Volunteers
- 250 people
- Sponsor
- KU Leuven
Hepatocellular Carcinoma
CT/MR-US Automatic Fusion System in Pre-procedure Planning for Radiofrequency Ablation
To prospectively evaluate the technical success rate of real-time computed tomography/CT/magnetic resonance imagingMR and -ultrasound (CT/MRI-US) automatic fusion system and the long-term therapeutic efficacy of radiofrequency…
- Trial name
- NCT04844112
- Testing
- automatic CT/MRI-US fusion system guided radiofrequency ablation
- Volunteers
- 139 people
- Sponsor
- Seoul National University Hospital
Intestinal Polyps
Comparison of Narrow Band Imaging With or Without Magnifying Colonoscopy
The aim of this study is to evaluate the usefulness of magnifying colonoscopy with narrow band imaging.
- Trial name
- NCT01577875
- Testing
- NBI with magnification
- Where
- South Korea
- Volunteers
- 122 people
- Sponsor
- Seoul National University Hospital
Parkinsons
Investigations of Dementia in Parkinson Disease
The purpose of this study is to use a brain imaging method called Pittsburgh B (PIB) Positron Emission Tomography (PET) and Vesicular Cholinergic Transport (VAT) PET to determine dementia subtypes in patients with Parkinson…
- Trial name
- PIB (NCT02763683)
- Testing
- PiB and VAT
- Where
- United States
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Carotid Plaque, Ischemic Stroke
Evaluation of Vulnerability of Carotid Plaques and Prediction of Cardio-Cerebrovascular Event Using Ultrasonic Imaging
This study included patients with carotid artery atherosclerotic plaques to conduct multimodal ultrasound examinations, aiming to establish a plaque vulnerability assessment model based on ultrasonic imaging indicators, clinical…
- Conditions
- Carotid Plaque, Ischemic Stroke, Cardiovascular Events
- Trial name
- NCT06473272
- Testing
- Cardiovascular and cerebrovascular diseases
- Where
- China
- Volunteers
- 600 people
- Sponsor
- Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
Mild Cognitive Impairment (MCI)
Non-invasive Deep Brain Stimulation to Enhance Motor Skill Acquisition in Individuals With Mild Cognitive Impairment
The goal of this study is to investigate the impact of non-invasive deep brain stimulation on motor skill acquisition in individuals with Mild Cognitive Impairment.
- Trial name
- NCT07092839
- Testing
- transcranial electric stimulation
- Where
- 2 sites in Switzerland
- Volunteers
- 15 people
- Sponsor
- Friedhelm Hummel
Spinal Cord Stimulation
New Markers to Assess the Efficacity of Spinal Cord Stimulation for the Treatment of Chronic Lower Limb Pain (MOTIVE)
By combining the usual care of patients eligible for spinal cord stimulation (SME) with measurements of the HRV index (Heart Rate Variability), objective measurements of activity (number of steps, quality of sleep) and…
- Trial name
- NCT04785001
- Where
- France
- Volunteers
- 25 people
- Sponsor
- Fondation Ophtalmologique Adolphe de Rothschild
Coronary Disease
Evaluating New Radiation Techniques for Cardiovascular Imaging
Title: Evaluating New Radiation Techniques for Cardiovascular Imaging Background: Cardiac CT angiography is associated with radiation exposure.
- Trial name
- NCT01621594
- Testing
- Cannon Aquilion ONE CT system
- Where
- United States
- Volunteers
- 5,000 people
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Anxiety Disorders, Fear
Brain Imaging Changes in Fear and Anxiety
The purpose of this study is to use brain imaging technology to investigate brain changes in people exposed to predictable versus unpredictable unpleasant stimuli.
- Trial name
- NCT00047853
- Testing
- Shock device, Acoustic startle
- Where
- United States
- Volunteers
- 1,080 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Cancer of the Uterine Cervix
Diagnostic Performance of 18F-FDG-PET and Diffusion-weighted MRI in the Assessment of Stage IB to IIB2 Cervical Squamous-cell Carcinoma Response to Concomitant Radiochemotherapy and Brachytherapy
Rationale: The benefit-risk ratio of surgery following concomitant radiochemotherapy and brachytherapy remains to be defined in cervical squamous-cell carcinoma (SCC) treatment.
- Trial name
- ERRICC (NCT01663753)
- Testing
- 18F-FDG-PET
- Where
- 24 sites in France
- Volunteers
- 146 people
- Sponsor
- Hospices Civils de Lyon
Defibrillators, Implantable, Heart Failure, Congestive
Implantable Cardioverter Defibrillators And Magnetic Resonance Imaging of the Heart at 1.5 Tesla
To evaluate short-term and long-term effects by MR imaging on the technical and functional status of implantable cardioverter defibrillators.
- Trial name
- NCT00356239
- Where
- Germany
- Volunteers
- 25 people
- Sponsor
- University Hospital, Bonn
Myocardial Infarction
Evaluation of a Strategy Guided by Imaging Versus Systematic Coronary Angiography in Elderly Patients With Ischemia
The WHO predicts that cardiovascular morbi-mortality will increase by 120-137% within 20 years due to the aging population. Myocardial infarction without ST segment elevation (NSTEMI) is the most common form of infarction.
- Trial name
- EVAOLD (NCT03289728)
- Testing
- Stress single photon emission CT (SPECT) or Stress ultrasound with dobutamine (DSE), Cornorary angioplasty
- Where
- 2 sites in France
- Volunteers
- 588 people
- Sponsor
- University Hospital, Grenoble
Alzheimer Disease (AD), Mild Cognitive Impairment (MCI)
Use of a Mobile Brain-Body Imaging Approach to Evaluate the Effects of Rhythmic Auditory Stimulation on Gait and Brain Function in Alzheimer's Disease
Alzheimer's Disease (AD) is associated with impairments in both gait and cognition, significantly increasing fall risk. Falls are a leading cause of injury-related disability in older adults, and individuals with AD experience a…
- Trial name
- NCT07659964
- Testing
- Metronome
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Boston University Charles River Campus
Mouth Neoplasms, Oropharyngeal Neoplasms
F-18 Fluorothymidine PET Imaging for Early Evaluation of Response to Therapy in Head & Neck Cancer Patients
This is an imaging protocol only, not a therapeutic study. The primary goal of the proposed study is to examine the utility of a new imaging study, Positron Emission Tomography with F-18 Fluorothymidine (FLT PET), in the early…
- Conditions
- Mouth Neoplasms, Oropharyngeal Neoplasms, Laryngeal Neoplasms, Head and Neck Neoplasms
- Trial name
- NCT00721799
- Testing
- 18F-Fluorothymidine PET scan
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- University of Iowa
Coronary Artery Disease
Gadobutrol/Gadavist-enhanced Cardiac Magnetic Resonance Imaging (CMRI) to Detect Coronary Artery Disease (CAD)
Participants being evaluated for suspected or known Coronary artery Disease (CAD) based on signs and/or symptoms, will be invited to participate in the study.
- Trial name
- GadaCAD 1 (NCT01890421)
- Testing
- Gadobutrol (Gadovist, Gadavist, BAY86-4875)
- Where
- 23 sites in United States, France and 5 more
- Volunteers
- 426 people
- Sponsor
- Bayer
Cochlear Implant
Role of Diagnostic Imaging in Cochlear Implant
cochlear implant is a well accepted treatment to profound sensorineural hearing loss. Imaging provides essential information about anatomical Variants that could be riskyand should be considered by cochlear implant surgeon and…
- Trial name
- NCT04711538
- Testing
- MRI
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Sohag University