Clinical trials: Imaging
Prostate Cancer
Abi/Pred + ADT vs ADT in PSMA-Positive, Conventionally Node-Negative Prostate Cancer
The advent of PSMA-PET has improved sensitivity and specificity in staging prostate cancer, particularly in intermediate- and high-risk disease.
- Trial name
- NCT07237269
- Testing
- Androgen Deprivation Therapy (ADT), Abiraterone, Prednisone
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- University of Nebraska
Insulinoma
[68Ga]Ga-HBED-CC-exendin-4 and [68Ga]Ga-NOTA-exendin-4 PET/CT Imaging in the Same Group of Insulinoma Patients
Glucagon-like peptide-1 receptor (GLP-1R)-targeted PET imaging with 68Ga-labeled compounds is able to provide superior sensitivity and specificity to detect insulinoma, like the widely studied [68Ga]Ga-NOTA-exendin-4.
- Trial name
- NCT05034783
- Testing
- [68Ga]Ga-HBED-CC-exendin-4, [68Ga]Ga-NOTA-exendin-4
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Peking Union Medical College Hospital
Non Alcoholic Fatty Liver, Hepatitis B
Combi-elastography Assessment of Chronic Liver Disease Multi-center Study
HITACH developed a new combi-elastography imaging technology combines shear wave imaging and strain imaging technology. In the study, not only the F index which is related to the stage of liver fibrosis can be obtained, but also…
- Conditions
- Non Alcoholic Fatty Liver, Hepatitis B, Drug-induced Liver Injury
- Trial name
- NCT04625166
- Where
- China
- Volunteers
- 880 people, healthy volunteers welcome
- Sponsor
- Chinese PLA General Hospital
Tachycardia, Supraventricular, Tachycardia, Ventricular
Accuracy and Safety Study of the Magnetecs CGCI System for Intracardiac Mapping
The Magnetecs Catheter Guidance Control and Imaging (CGCI) system is a magnetic remote navigation system which is comprised of a magnetic chamber of eight electromagnets around the patient torso.
- Trial name
- RICTAM (NCT01222156)
- Testing
- Remote magnetic navigation, Magnetecs Catheter Guidance Control and Imaging system
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Magnetecs Corporation
Coronary Artery Disease
Diagnostic Imaging Strategies for Patients With Stable Chest Pain and Intermediate Risk of Coronary Artery Disease
The primary hypothesis is that computed tomography (CT) is superior to invasive coronary angiography (ICA) concerning the primary endpoint MACE (MACE = major adverse cardiovascular event; defined as at least one of the following…
- Trial name
- DISCHARGE (NCT02400229)
- Testing
- Computed tomography angiography (cardiac CT), Invasive coronary angiography (ICA)
- Where
- 20 sites in Austria, Czechia and 13 more
- Volunteers
- 3,546 people
- Sponsor
- Charite University, Berlin, Germany
Attention Deficit Disorder With Hyperactivity
Cerebellar Loops and Attention Deficit Hyperactivity Disorder (ADHD)
The aim of this study is to investigate the integrity of connectivity between the neocortex and the cerebellum in the Attention Deficit Hyperactivity Disorder (ADHD).
- Trial name
- TDA/H (NCT00684931)
- Testing
- Imaging
- Where
- 2 sites in France
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bordeaux
Irritable Colon, Irritable Bowel Syndrome (IBS)
Study On The Effect Of GW876008 On Cerebral Blood Flow In Irritable Bowel Syndrome (IBS) Patients And Healthy Volunteers
This is a three-period crossover study to compare GW876008 and placebo to see if GW876008 will normalise blood flow responses after different emotional stimuli.
- Trial name
- NCT00376896
- Testing
- GW876008 200mcg, GW876008 20mcg
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Uterine Cancer
[18F]FES PET/.CT in Uterine Cancer
Women with known or suspected recurrent or metastatic uterine cancer may be eligible for this study. Patients may participate in this study if they are at least 18 years of age, most participants will be receiving care at the…
- Trial name
- NCT05916196
- Testing
- 18F-Fluoroestradiol
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Abramson Cancer Center at Penn Medicine
Multiple Myeloma, Disease of the Marrow
Evaluation of PET/MR and PET/CT Imaging for Bone Marrow Lesions
Developing an MRI protocol at 1.5 T allowing quantification of the hematopoietic, fatty and trabecular moieties of marrow. An ideal protocol would differentiate red marrow from neoplastic cellular infiltration, and detect loss of…
- Conditions
- Multiple Myeloma, Disease of the Marrow, Osteoporosis
- Trial name
- NCT01880762
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Painful Hip, Fonctional Impotence After Minor Trauma (Fall)
Radiologist Diagnostic Performance Versus Artificial Intelligence (AI)
In France, femoral neck fracture is mainly detected with interpretation of pelvis/hip X-ray imaging (French Health Authority recommandation).
- Trial name
- RAVIA (NCT04304742)
- Testing
- hip standard radiography/ CT scan/ MRI
- Where
- France
- Volunteers
- 1,000 people
- Sponsor
- University Hospital, Montpellier
Developmental Coordination Disorder
Does tDCS Improve Motor Learning in Children With DCD?
Transcrainial direct current stimulation (tDCS) has become increasingly popular over the past decade. tDCS is a safe and well-studied form of non-invasive brain stimulation.
- Trial name
- NCT03453983
- Testing
- Transcrainial Direct Current Stimulation (tDCS)
- Where
- Canada
- Volunteers
- 35 people
- Sponsor
- University of Calgary
Alzheimer Disease
Evaluation of Flortaucipir PET Signal and Cognitive Change in Early Alzheimer's Disease
This study will evaluate whether visual interpretation of flortaucipir-PET (positron emission tomography) scans, examining patterns of tracer uptake at baseline, can predict the rate of clinically-meaningful cognitive decline due…
- Trial name
- NCT03901105
- Testing
- flortaucipir F18, Brain PET Scan
- Where
- United States
- Volunteers
- 205 people
- Sponsor
- Avid Radiopharmaceuticals
Chronic Kidney Disease
Chronic Kidney Disease and Bone - Correlation Between 18F-PET-TT Imaging and Histomorphometry of Bone in CKD Patients
Chronic kidney disease (CKD) is an increasing public health problem and the number of patient with chronic kidney disease is increasing worldwide.
- Trial name
- CKD-Bone (NCT02967042)
- Testing
- 18F-PET-TT
- Where
- Finland
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Turku University Hospital
Bipolar Disorder
fMRI of Flight of Ideas in Bipolar Disorder
Bipolar disorder is a mental disease characterized by mood dysregulation and arises from manic, depressive or mixed episodes. The observations of the patient's speech and language behaviour due to flight of ideas or loss of goal…
- Trial name
- i-TCP (NCT02794129)
- Testing
- Functional Magnetic Resonance Imaging
- Where
- France
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- CHU de Reims
Hip Fractures, Femur Fractures
Gonadal Radiation Exposure and Risk Secondary to Fluoroscopic Imaging During Trauma Surgery
The aim of this cohort study is to precisely measure patients' exposure to gonadal radiation during orthopaedic trauma surgery involving the acetabulum, pelvis, hip, and femur, and to apply these findings to a previously…
- Conditions
- Hip Fractures, Femur Fractures, Acetabular Fractures, Pelvic Injuries
- Trial name
- NCT02267330
- Testing
- Exposure Recording
- Volunteers
- 135 people
- Sponsor
- University of Utah
Prostate Cancer, Prostate Adenocarcinoma
MRI Risk Maps for Prostate Cancer Diagnosis Using Targeted Biopsy
Doctors leading this study hope to learn about a software that researchers at the University of Chicago have developed to help analyze radiographic images (different techniques for taking images that allow doctors to visualize…
- Conditions
- Prostate Cancer, Prostate Adenocarcinoma, Prostate Neoplasm
- Trial name
- NCT05710380
- Testing
- Risk Map Decision Support System (DSS)., Magnetic Resonance Imaging (MRI), Magnetic Resonance Imaging (MRI) Guided Biopsy
- Where
- 2 sites in United States
- Volunteers
- 180 people
- Sponsor
- University of Chicago
CAD
Technical Development of Cardiovascular Magnetic Resonance Imaging (CMR) Using a Low Specific Absorption Rate (SAR) Scanner System
Background: Researchers are testing version of a system known as a magnetic resonance imagining (MRI) scanner that uses strong magnetic fields, radio waves and the like to create images of the organs in the body.
- Trial name
- NCT03331380
- Testing
- MRI scan - obj 1, MRI scans - obj 2, MRI scans - obj 3
- Where
- United States
- Volunteers
- 2,950 people, healthy volunteers welcome
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Breast Cancer
Pilot Study to Evaluate High Resolution PET Image-Guidance for Sampling of Breast Abnormalities
The purpose of this pilot clinical study is to test a methodology for using high-resolution Positron Emission Tomography (PET) imaging to guide vacuum-assisted core biopsy of breast abnormalities identified on PET.
- Trial name
- PEM-BX (NCT00606931)
- Testing
- Stereo Navigator Accessory to PEM Flex PET Scanner
- Where
- 5 sites in United States
- Volunteers
- 22 people
- Sponsor
- Naviscan PET Systems
Eye Diseases
Pix2pix Networks for Scheimpflug Corneal Tomography Image Generation
Computer-aided medical image analysis has advantages, but requires large amounts of training data, which are scarce and costly to obtain, are subject to privacy concerns, and are often highly imbalanced, with over-representation…
- Trial name
- NCT04582253
- Testing
- Scheimpflug Camera Corneal Tomography
- Where
- Egypt
- Volunteers
- 923 people, healthy volunteers welcome
- Sponsor
- Assiut University
Aortic Valve Disease
A Clinical and Imaging Registry of Transcatheter Aortic Valve Implantation Using JenaValve System/ J-Valve System for Patients With Pure Aortic Regurgitation
Aortic regurgitation (AR) is not uncommon. Transcatheter aortic valve implantation (TAVI) for treating pure aortic regurgitation is a potential future treatment option for pure AR especially in patients having high risk for open…
- Trial name
- CAIR-JAR (NCT07021612)
- Testing
- JenaValve, J-Valve
- Where
- Hong Kong
- Volunteers
- 30 people
- Sponsor
- Prince of Wales Hospital, Shatin, Hong Kong