Clinical trials: Imaging
Type 1 Diabetes, Type 2 Diabetes
A Trial of 18F-AV-133 Positron Emission Tomography (PET)
The purpose of this study is to evaluate the safety and pancreas imaging properties of 18F-AV-133.
- Trial name
- NCT01515384
- Testing
- 18F-AV-133
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Avid Radiopharmaceuticals
Amyotrophic Lateral Sclerosis
ALS Spinal Cord Gray and White Matter Study
This study aims to measure in vivo the spinal cord gray and white matter in patients with Amyotrophic Lateral Sclerosis and healthy persons that match the patients' age and sex using rAMIRA imaging, a novel Magnetic Resonance…
- Trial name
- NCT05764434
- Testing
- Magnetic Resonance Imaging
- Where
- Switzerland
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Alzheimer Disease, Mild Cognitive Impairment
Enhancing Memory in Mild Cognitive Impairment and Early Stage Alzheimer's Disease
The investigators have developed a low-risk transcranial Electrical Stimulation (tES) treatment that has improved learning and performance in young adults up to nearly 4 times when compared with a sham control.
- Trial name
- MEMORI (NCT05077826)
- Testing
- North Coast Medical Activadose II
- Where
- United States
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- The Mind Research Network
Healthy
Magnetic Resonance Imaging of Human Supraclavicular Brown Adipose Tissue - MIBAT Study
Brown adipose tissue (BAT) is unique in its capability to convert chemical energy directly into heat. Active BAT increases energy expenditure and can thereby counteract obesity and insulin resistance.
- Trial name
- MIBAT (NCT02682706)
- Where
- 2 sites in Switzerland
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Abdominal Aortic Aneurysm
PET Imaging of MMP Activation in AAA: Clinical Component
A first-in-human evaluation of [64Cu]-RYM2 with PET/CT will be performed to: a) assess its safety, biodistribution, and radiation dosimetry in normal volunteers (WU) and; b) in AAA patients undergoing surgery (WU and Yale)…
- Trial name
- PET AAA (NCT07473102)
- Testing
- Cu-64-RYM2, PET imaging using Cu-64
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Hip Pain &Disorders
Role of Magnetic Resonance Imaging in Assessment of Patients With Hip Pain
To evaluate the role of Magnetic Resonance Imaging in the assessment and diagnosis of patients presenting with hip pain.
- Trial name
- Hip MRI (NCT07802795)
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Sohag University
Healthy
Organ Interaction Patterns in Healthy Individuals for Improved PET/CT Diagnostics
The study titled "Study to determine interaction patterns of different organs in healthy volunteers as a basis for better patient diagnostics using PET/CT imaging" is designed to investigate the interaction patterns of different…
- Trial name
- Healthy-PET (NCT05936411)
- Testing
- Siemens Quadra PET/CT and [18F]FDG, Apple i-Watch
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Fertility
Validation Study Using a Time-lapse Morphometry MIRI Imaging Incubator
The purpose of this study is to evaluate the safety and efficacy of the MIRI-TL time-lapse incubator and CultureCoin dish compared to standard big-box incubators and standard culture dishes used for embryo culture.
- Trial name
- TiMMI (NCT02852356)
- Testing
- MIRI-TL Incubator
- Where
- United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Ovation Fertility
Age-Related (Dry) Macular Degeneration, Age-Related Macular Degeneration (AMD)
MIND-AMD Study: a Multidisciplinary Investigation of Neuroretinal Damage in Age-related Macular Degeneration.
Age-related macular degeneration (AMD) is the major cause of legal blindness in developed countries. Intermediate AMD represents the most frequent stage.
- Conditions
- Age-Related (Dry) Macular Degeneration, Age-Related Macular Degeneration (AMD), AMD Population - Intermediate or Advanced AMD, AMD and Macular Edema
- Trial name
- MIND-AMD (NCT07847151)
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- IRCCS San Raffaele
Cystic Fibrosis (CF)
MRI Assessment of Lung Airways in Cystic Fibrosis: Evaluate MRI's Ability to Detect Changes in Airway Structure .
This study is being done to determine whether MRI can produce high quality lung and airway images in healthy and CF patients and if MRI can be used to evaluate size and shape of the airways with computer assistance.
- Trial name
- UTE Airway MR (NCT07454681)
- Testing
- Advanced ultrashort echo time (UTE) MRI - Ultrashort echo time (UTE) imaging is a technique that can quickly capture the fast-decaying 1H lung signal., Multiple Breath Wash out (MBW)
- Where
- Canada
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- The Hospital for Sick Children
Type 2 Diabetes Mellitus
An Investigation Into Bone Micro-architecture in Women With Type 2 Diabetes
The number of people with type 2 diabetes is growing. This puts a lot of pressure on the health care systems. Type 2 diabetes is often associated with health problems, like poor eyesight, muscle coordination, muscle strength, and…
- Trial name
- NCT00982371
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hamilton Health Sciences Corporation
Drug Effect
Neuroimmune Effects of Opioid Administration
Preclinical research indicates acute opioid administration evokes an immune response in the periphery and brain. Here, we will translate those preclinical findings to healthy human volunteers and quantify the neuroimmune response…
- Trial name
- NOA (NCT03801629)
- Testing
- High Morphine Dose, Low Morphine Dose
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Yale University
Chronic Obstructive Pulmonary Disease (COPD)
Upper Airway Morphology and Physiology During Graded Positive Pressure and Nasal High Flow: An MRI Study
This study investigates the effects of graded nasal high flow (NHF) and continuous positive airway pressure (CPAP) on upper airway morphology and respiratory physiology in healthy volunteers and patients with COPD.
- Trial name
- AIR-MRI (NCT07886502)
- Testing
- Nasal High Flow, Continuous Positive Airway Pressure
- Where
- Germany
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Klinikum Dortmund Wirbelsäulenchirurgie
Healthy
Magnetic Resonance Imaging of the Effect of Music Listening on Brain Activity Under Anesthesia
This study is to better understand the systems-level neuronal mechanisms by which general anesthetics produce loss of consciousness.The researchers believe that anesthetics suppress consciousness by disrupting the functioning of…
- Trial name
- NCT04464265
- Testing
- Functional Magnetic Resonance Imaging (fMRI)
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Cardiomyopathy, Hypertrophic, Dilated Cardiomyopathy
UTSW HP [13-C] Pyruvate Injection in HCM
The study objective is to identify the earliest changes in energy substrate metabolism in patients with cardiomyopathies (CMP). To achieve this objective, we plan first to test the hypothesis that patients with CMP present focal…
- Conditions
- Cardiomyopathy, Hypertrophic, Dilated Cardiomyopathy, Duchenne Muscular Dystrophy, Cardiac Sarcoidosis
- Trial name
- HPHCM (NCT03057002)
- Testing
- Hyperpolarized 13C-Pyruvate
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Alcoholism
Imaging Cannabinoid CB1 Receptors in Alcohol Dependence
The cannabinoid type 1 (CB1) receptor is a protein found in the brain that is involved with the effects of marijuana; it may also play a role in the effects of alcohol dependence and withdrawal.
- Trial name
- NCT00816439
- Where
- United States
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Breast Abnormality Diagnosis
CONFIDENCE Registry
This registry has been designed to obtain real-life, post-market data on the use of the Imagio breast imaging system. This registry is sponsored by Seno Medical Instruments, Inc., the manufacturer of the device.
- Trial name
- CONFIDENCE (NCT05084729)
- Testing
- Imagio OA/US
- Where
- 3 sites in Netherlands
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- Seno Medical Instruments Inc.
Vagus Nerve Diseases, Diagnoses Disease
Validity and Inter-rater Reliability fo the Vagus Nerve Neurodynamic Test Among Healthy Subjects
Vagus nerve neurodynamic test (VN-NDT) will be validated detecting the changes in vagus nerve anatomical position due to the combination of movements of the test.
- Trial name
- NCT04192877
- Testing
- Vagus Nerve Neurodynamic test
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Turin, Italy
Breast Cancer
Evaluation of a 3D Functional Metabolic Imaging and Risk Assessment System in Classifying Women for Likelihood of Breast Cancer
The study objective is to evaluate the added value of MIRA technology as an adjunct to mammography in the detection of malignant breast lesions in women with dense breast and/or at elevated risk of breast cancer.
- Trial name
- NCT03296683
- Testing
- MIRA device imaging
- Where
- Italy
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- Real Imaging Ltd.
Prostate Adenocarcinoma, Stage I Prostate Cancer AJCC v8
rhPSMA-73 PET-MRI Imaging for the Detection of Prostate Cancer Among Men Who Are Otherwise Candidates for Active Surveillance
This clinical trial evaluates whether positron emission tomography-magnetic resonance imaging (PET-MRI) using the radioactive drug radiohybrid prostate-specific membrane antigen (rhPSMA)-7.3 may help in detecting higher grade or…
- Conditions
- Prostate Adenocarcinoma, Stage I Prostate Cancer AJCC v8, Stage IIA Prostate Cancer AJCC v8, Stage IIB Prostate Cancer AJCC v8
- Trial name
- NCT05852041
- Testing
- Biopsy of Prostate, Decipher Prostate Cancer Test, Flotufolastat F-18 Gallium
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Northwestern University
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