Clinical trials: IgE-Mediated Food Allergy
Food Hypersensitivity, Immune System Diseases
Oral Immunotherapy in Food Allergy in Finland
The outcomes of oral immunotherapy (OIT) in food allergy study will provide more knowledge of oral immunotherapy. So far the OIT has showed in clinical experiments to be a interesting way to increase the unresponsiveness in…
- Conditions
- Food Hypersensitivity, Immune System Diseases, Anaphylaxis
- Trial name
- NCT02640014
- Testing
- Milk
- Where
- Finland
- Volunteers
- 250 people
- Sponsor
- Helsinki University Central Hospital
Food Allergy, Peanut Allergy
Omalizumab in the Treatment of Peanut Allergy
The purpose of this study is to determine if treatment with omalizumab (Xolair, anti-IgE) can eliminate or reduce symptoms of peanut allergy.
- Trial name
- NCT00949078
- Testing
- omalizumab
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- Johns Hopkins University
Food Allergy in Children, Legumes Allergy
Improving Diagnosis of Legume Allergy in Children
In France, almost 15% of serious food allergies in children are caused by legumes, especially peanuts. Other legumes like soy, lentils, peas, lupin, chickpeas, beans, and fenugreek can also cause allergic reactions.
- Conditions
- Food Allergy in Children, Legumes Allergy, Molecular Diagnostic
- Trial name
- LACID (NCT06995950)
- Volunteers
- 90 people
- Sponsor
- Central Hospital, Nancy, France
IgE-mediated Abdominal Pain
INhaled Salbutamol vs Placebo for the Treatment of Acute IgE-mediated Abdominal Pain From Allergic Food REactions
The goal of this study is to assess the efficacy of inhaled salbutamol to treat abdominal pain during food allergic reactions. Patients experiencing abominal pain as a result of a food allergic reaction during a food challenge in…
- Trial name
- INSPIRE (NCT05653024)
- Testing
- Salbutamol
- Where
- Canada
- Volunteers
- 24 people
- Sponsor
- Philippe Bégin
Oral Allergic Syndrome, Allergic Reaction Caused by Food (Disorder)
Efficacy of Oral Tolerance Induction to Raw Apple
The aim of the study was to describe an intensive ultra rush (UR) protocol of raw Golden apple (RGA) reintroduction in 28 in-patients, show the protocol's tolerance and the patients' follow-up at 2 months and 1 year.
- Trial name
- RAAP (NCT04116580)
- Testing
- RAAP - for Raw Apple in connection with re-contact with the raw apple according to an Ultra-Rush protocol
- Volunteers
- 28 people
- Sponsor
- Michel Bouvier
Allergy to Fish, Allergy to Shrimp
Pilot Study on Traditional Chinese Medicine and Food Allergy
Recently, there has been an increasing interest in using traditional Chinese medicine for food allergy. The Harvard group has successfully demonstrated the Food Allergy Herbal Formula - FAHF2 completely blocked peanut-induced…
- Conditions
- Allergy to Fish, Allergy to Shrimp, Allergy to Crab
- Trial name
- TCMFA (NCT02490813)
- Testing
- Treatment - Chinese Herbal Formula - X
- Where
- Hong Kong
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Hong Kong Sanatorium & Hospital
Cow's Milk Allergy
Diagnostic Accuracy and Safety of DBV1605 for the Diagnosis of Non-IgE Mediated Cow's Milk Allergy in Children
Study to assess the diagnostic accuracy (sensitivity, specificity, positive and negative predictive value) of DBV1605 for the diagnosis of non-Immunoglobulin E (IgE) mediated cow's milk allergy (CMA) in children with symptoms…
- Trial name
- APTITUDE (NCT04492683)
- Testing
- DBV1605
- Where
- 33 sites in United States, Canada and 2 more
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- DBV Technologies
Food Allergy in Infants
The Tolerance of Organic Formula Milk and Its Fecal Microbiome Characteristic in Infants
This interventional study aims to investigate the tolerance of organic formula milk on infants supplemented with organic formula milk.
- Trial name
- TOFeM (NCT05215080)
- Testing
- Organic Formula Milk
- Where
- Indonesia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Hasanuddin University
Food Allergy in Children
Friends, Family & Food: Food Allergy App for Youth - II
Objective: This Phase II STTR grant incorporated user feedback collected in an earlier development project to build interactive, web-based software that helps children with food allergies learn about their condition and gain…
- Trial name
- F3A-App (NCT05111938)
- Testing
- Friends, Family, and Food App (F3A-App)
- Volunteers
- 80 people
- Sponsor
- Rhode Island Hospital
Food Allergy in Children
Efficacy and Safety of Cashew Nut Oral Immunotherapy in Children
Allergy to nuts (cashew, pistachio, walnut, exotic nuts) is a frequent allergy in children, with a prevalence of up to 4.9% of the population and a low resolution rate (9%).
- Trial name
- CAJESITO2 (NCT05821621)
- Testing
- no intervention
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Central Hospital, Nancy, France
Atopy, Atopic Dermatitis Eczema
Breast Milk: Influence of the Micro-transcriptome Profile on Atopy in Children Over Time
This is an observational cohort study of 221 breast-feeding mother-infant dyads delivered at term. The goal of the study is to investigate whether levels of immune-related microRNAs (miRNAs) in maternal breast milk (MBM)…
- Conditions
- Atopy, Atopic Dermatitis Eczema, Wheezing, Food Allergy in Infants
- Trial name
- IMPACT (NCT04017520)
- Where
- United States
- Volunteers
- 221 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Food Allergy
Study Using Xolair in Rush Multi Oral Immunotherapy in Multi Food Allergic Patients
This is a pilot randomized, double-blind, placebo controlled study which will be conducted at a single center. All participants will receive oral immunotherapy for their specific food allergies (limited to 5 of those food…
- Trial name
- MAP-X (NCT02643862)
- Testing
- Xolair
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Stanford University
Food Allergy
Multi OIT to Test Immune Markers After Minimum Maintenance Dose
Few studies have been conducted to optimize safety of multiple food allergen oral immunotherapy (OIT) in conjunction with Omalizumab as well as to identify the immunological mechanism(s) underlying any long-lasting effects of…
- Trial name
- NCT03181009
- Testing
- Omalizumab, Food Flour Allergens
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- Andrew Long, PharmD
Allergy;Food, Adherence, Treatment
The Food Allergy Superheroes Training (FAST) Program
Among children with a food allergy, strict avoidance (e.g., elimination of allergenic foods from one's diet) is the only intervention capable of preventing potentially devastating health-related sequelae including anaphylaxis and…
- Conditions
- Allergy;Food, Adherence, Treatment, Child, Only
- Trial name
- NCT04400214
- Testing
- Food Allergy Superheroes Training (FAST) Program, Food Allergy Knowledge Intervention
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Kent State University
Atopic Dermatitis, Food Allergy
An Innovative Probiotic Product With Antiallergic Properties
Allergic diseases are currently one of the most important problem in medicine. Research confirms that probiotics administered during the formation of the intestinal ecosystem and the maturation of the immune system can positively…
- Conditions
- Atopic Dermatitis, Food Allergy, Effects of Probiotics
- Trial name
- NCT04738565
- Testing
- Probiotic preparation, Maltodextrin
- Where
- Poland
- Volunteers
- 150 people
- Sponsor
- Children's Memorial Health Institute, Poland
Food Allergy
Low Dose Multi-OIT for Food Allergy (LoMo)
Oral immunotherapy (OIT) is a food allergy treatment where small amounts of the food a child is allergic to is eaten and gradually increased over time with the aim to be able to eat a certain amount of the allergen without…
- Trial name
- LoMO (NCT03799328)
- Testing
- multi-OIT
- Where
- Canada
- Volunteers
- 18 people
- Sponsor
- The Hospital for Sick Children
Child Allergy, Food Allergy
Impact of an Educational Tool on Quality of Life and Anxiety in Parents of Children With Nut Allergy
The number of young children with food allergy, in particular with nut allergy, is increasing worldwide. A diagnosis of nut allergy can cause much anxiety in parents.
- Trial name
- NCT05458882
- Testing
- "living with food allergy" educational booklet
- Where
- Ireland
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Children's Health Ireland
Eczema, Egg Allergy
Persistence of Oral Tolerance to Peanut
ITN049AD (LEAP-On) Study is a continuation of the ITN032AD LEAP Study (NCT00329784). Peanut Allergy, a recognized public health concern, is a common and potentially life-threatening food allergy for which there is no treatment.
- Conditions
- Eczema, Egg Allergy, Food Allergy, Hypersensitivity
- Trial name
- LEAP-On (NCT01366846)
- Testing
- Avoidance of peanut
- Where
- United Kingdom
- Volunteers
- 556 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Eosinophilic Gastroenteritis, Eosinophilic Esophagitis
Sirolimus for Eosinophil-Associated Gastrointestinal Disorders
Background: Eosinophil-associated gastrointestinal disorders (EGID) are a group of related disorders that affect the esophagus, stomach, and bowel.
- Trial name
- NCT01814059
- Testing
- sirolimus
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Food Allergy
Effectiveness of Dupilumab in Food Allergic Patients With Moderate to Severe Atopic Dermatitis
This study evaluates the effectiveness of Dupilumab in food allergic patients with moderate to severe Atopic Dermatitis (AD). Included patients participated in the BioDay Registry.
- Trial name
- NCT04462055
- Where
- Netherlands
- Volunteers
- 3 people
- Sponsor
- UMC Utrecht