Clinical trials: IgE-Mediated Food Allergy
Peanut Allergy
Understanding How the Immune System Responds to Viruses in Peanut Allergic Children Undergoing Peanut Oral Immunotherapy
The purpose of this study is to find out if there is a way to treat children with peanut allergy to help lower the risk of severe allergic reactions and also cause them to lose their allergy to peanuts and to understand what…
- Trial name
- DCOIT (NCT01074840)
- Testing
- Peanut flour
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- University of Texas Southwestern Medical Center
Food Allergy
Partially Hydrolyzed Whey Formula in Cow's Milk Allergic Patients
Cow's milk (CM) allergy is the most common food allergy in children, affecting 2-3% of infants. In formula-fed infants with CM allergy, extensively hydrolyzed or amino acid-based infant formulas are typically recommended.
- Trial name
- NCT02397876
- Testing
- Partially Hydrolyzed Whey formula
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Food Allergy, Peanut Allergy
Study to Assess Tolerance of Traces in Peanut/Tree Nut Allergic Children.
This protocol will help better define whether patients with peanut and/or tree nut food allergy can tolerate traces in products with precautionary allergen labelling.
- Conditions
- Food Allergy, Peanut Allergy, Tree Nut Allergy
- Trial name
- NCT03680066
- Testing
- Oral food challenge to foods with traces
- Where
- Switzerland
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University Hospital, Geneva
Peanut Allergy
The Safety and Efficacy of a Peanut Immunotherapy Dissolving Film for Peanut Allergy
The purpose of this study is to determine if a new method of administration of peanut sublingual immunotherapy, a dissolving peanut film, is effective.
- Trial name
- NCT01897077
- Testing
- Peanut Dissolving Film
- Where
- 2 sites in United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Peanut Allergy
Follow-up of the VIPES Study to Evaluate Efficacy and Safety of Viaskin Peanut in Adults and Children
The objectives of this open-label follow-up study for subjects who previously were randomized and have completed the VIPES study for the treatment of peanut allergy, are: To assess the efficacy of Viaskin Peanut after up to 36…
- Trial name
- OLFUS-VIPES (NCT01955109)
- Testing
- Viaskin Peanut 250 mcg
- Where
- 22 sites in United States, Canada and 2 more
- Volunteers
- 171 people
- Sponsor
- DBV Technologies
Food Allergy
iFAAM: The Impact of Proton-pump Inhibitors (Antacids) on Threshold Dose Distributions
In patients with a walnut allergy double blind placebo controlled food challenge with walnut will be combined with the intake of proton pump inhibitor (PPI) or with placebo to assess the impact of PPI on threshold level and on…
- Trial name
- iFAAM-PPI (NCT02552537)
- Testing
- Omeprazole
- Where
- 2 sites in Spain, Switzerland
- Volunteers
- 44 people
- Sponsor
- University of Zurich
Food Allergy
Molecular Analysis of IgE Antibodies in Walnut Allergic Patients
Accurate diagnosis of food allergy depends on the identification of the causative allergenic molecule(s). The proposed study intends to investigate and compare the pattern of IgE antibody sensitisation in walnut allergic subjects…
- Trial name
- NCT02295267
- Testing
- walnut allergy provocation
- Where
- Switzerland
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Children With Food Allergy
Health Related Quality of Life in Children With Food Allergy: Comparison to Controls and Other Chronic Diseases
The number of studies concerning health related quality of life (HRQL) in children with food allergy is very limited. Only one study to date has compared HRQL of a group of children with food allergy to data published on general…
- Trial name
- NCT02008643
- Testing
- filling questionnary to quality of life
- Where
- France
- Volunteers
- 861 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Food Allergy in Children
Friends, Family & Food: Food Allergy App for Youth ( F3A-App )
Objective: This Phase II STTR grant incorporated user feedback collected in an earlier development project to build interactive, web-based software that helps children with food allergies learn about their condition and gain…
- Trial name
- F3A-App (NCT05093114)
- Volunteers
- 39 people
- Sponsor
- Rhode Island Hospital
Allergies, Food Allergy
Omalizumab Weight-Based Dosing Efficacy Trial
This research is being conducted to assess the safety and effectiveness of increased dosing of Omalizumab for food allergies.
- Trial name
- OWED-T (NCT06943534)
- Testing
- 5mg/kg omalizumab injection, 15mg/kg omalizumab injection
- Where
- 3 sites in United States
- Volunteers
- 30 people
- Sponsor
- Massachusetts General Hospital
Food Allergies
Food Challenge at Home or in Medical Practice - the FoodCHOMP Study
This is a pilot, multi-centre, randomised clinical trial evaluating the safety and feasibility of a home-based oral food challenge in adults with low-risk food allergy labels.
- Trial name
- CHOMP (NCT06916819)
- Testing
- Home-Based Food Challenge, In-Clinic Food Challenge
- Where
- 2 sites in Australia
- Volunteers
- 120 people
- Sponsor
- Austin Health
Tree Nut Allergy, Food Allergy
Thresholds In Food Allergy evaluaTion And predictioN
Thresholds In food allergy evaluaTion And predictioN, a prospective, observational registry. The aim is to quantify food allergy thresholds in Canada and their clinical predictors.
- Trial name
- TITAN (NCT06038019)
- Testing
- Oral food challenge
- Where
- Canada
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Hamilton Health Sciences Corporation
Food Allergy, Food Allergy Peanut
EPAP, Interviewstudy
The goal of this observational study is to learn about repetitive anaphylactic reactions in food allergic patients and to compare the frequency of repetitive reactions between different elicitors in food allergic patients.
- Conditions
- Food Allergy, Food Allergy Peanut, Allergy, Anaphylactic Shock
- Trial name
- NCT06192914
- Where
- Germany
- Volunteers
- 322 people
- Sponsor
- Charite University, Berlin, Germany
Food Allergy to Fish
FAST Fish Phase IIb Clinical Trial for the Treatment of Fish Allergy by Subcutaneous Immunotherapy
This is a phase IIb clinical trial to investigate the efficacy and safety of subcutaneous immunotherapy with a modified parvalbumin called mCyp c 1 for the treatment of fish allergy to subjects allergic to fish.
- Trial name
- FASTIIb (NCT02382718)
- Testing
- FAST fish mCyp c 1
- Where
- 9 sites in Denmark, Greece and 4 more
- Volunteers
- 45 people
- Sponsor
- George Stavroulakis
Atopic Dermatitis, Food Allergies
Frequency of Food Allergy Confirm by Oral Food Challenge Among Foods Avoidance in Atopic Dermatitis Children
Atopic dermatitis can be caused by several factors, including food allergy. Currently, the diagnosis of food allergy often performing skin tests and measuring specific IgE foods that many studies have shown that about 53% of…
- Trial name
- NCT06947252
- Testing
- Oral food challenge test
- Where
- Thailand
- Volunteers
- 200 people
- Sponsor
- Mahidol University
Food Allergy in Children
Evaluate the Efficacy of the OITcontrol Application.
The main aim of this study is to evaluate the clinical efficacy of the OITcontrol application in patients undergoing OIT of eggs or milk used during the follow-up of this treatment.
- Trial name
- NCT05794568
- Testing
- OITcontrol app monitoring
- Where
- 7 sites in Spain
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Clinica Universidad de Navarra, Universidad de Navarra
Allergic Rhinitis, Food Allergy
Analysis of Immunological Reactions to Foods in Birch Pollen-Allergic Patients
A high number of birch pollen-allergic individuals develop hypersensitivity reactions to certain foods, e.g. apples. This food allergy is due to immunological cross-reactivity. Birch pollen-related foods contain proteins, e.g.
- Trial name
- NCT00787631
- Volunteers
- 30 people
- Sponsor
- Medical University of Vienna
Food Allergy in Children
Evaluation of The Food Allergy Mastery Program
The proposed research project will evaluate a novel behavioral intervention that promotes early adolescent food allergy self-management and adjustment through 1) food allergy education, 2) problem-solving, communication…
- Trial name
- NCT06034678
- Testing
- Food Allergy Mastery Program
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- Children's National Research Institute
Food Allergy
Fast Allergy Sensitivity Test
Irritable Bowel Syndrome (IBS), or functional colopathy, is a chronic disease that affects 10% to 20% of the world's population.This syndrome is characterized by chronic abdominal pain or discomfort as well as a change in bowel…
- Trial name
- FAST (NCT05072665)
- Testing
- HIGH ECHOENDOSCOPY WITH THE FAST PROCEDURE
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Clinique du Trocadéro
Asthma, Mastocytosis
Mast Cell Activation Test in Allergic Disease
Activation of mast cells in the immune system is known to cause allergic reactions sometimes with severe systemic symptoms. The investigators have recently developed a blood-based mast cell activation diagnostic test in which…
- Conditions
- Asthma, Mastocytosis, Mast Cell Activation Syndrome, Food Allergy
- Trial name
- NCT03406325
- Where
- Hong Kong
- Volunteers
- 19 people
- Sponsor
- Hong Kong Sanatorium & Hospital