Clinical trials: IVF
Frozen Embryo Transfer
The Association Between Serum E2 and P on the Day of FET and the Pregnancy Outcome
The outcomes of frozen embryo transfer (FET) have substantially improved over the last decade, due to the improvements in the cryopreservation process, Artificial endometrial preparation is typically accomplished by the…
- Trial name
- FET (NCT04114500)
- Testing
- serum estradiol and progesterone
- Where
- Bahrain
- Volunteers
- 402 people
- Sponsor
- Al Baraka Fertility Hospital
Maternal Distress, Child Development
In Vitro Fertilization (IVF) and Prenatal Effects Independent of Genetics
This study examines how maternal stress during pregnancy affects infant brain and behavioral development, focusing on whether these effects are due to the prenatal environment or shared genes.
- Trial name
- NCT07296107
- Testing
- Prenatal maternal psychosocial and biological assessment protocol
- Where
- United States
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Columbia University
Endometriosis, Omics
SH-SDU Shandong Endometriosis Reproductive Cohort
Endometriosis (EMs) is a chronic, estrogen-dependent, multi-systemic disease that affects approximately 190 million women worldwide.
- Conditions
- Endometriosis, Omics, Assisted Reproductive Technology
- Trial name
- NCT07558629
- Where
- China
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- The Second Hospital of Shandong University
Infertility
US Eeva™ Pregnancy Investigational Clinical Study (US EPIC)
The purpose of this clinical investigation is to gather data to evaluate the impact of using Eeva with traditional morphology grading on implantation rates.
- Trial name
- US EPIC (NCT01671657)
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Progyny, Inc.
Endometrioma
Effect of Prolonged GnRh Agonists on Results of Intracytoplasmic Sperm Injection (ICSI ) in Endometrioma Patients
Investigators compare ICSI results for endometrioma patients with or without cyst aspiration if more than 5cm \&with or without GnRh agonists for all endometrioma patients
- Trial name
- GnRh (NCT02737800)
- Testing
- endometrioma aspiration, GnRh agonist ( Decapeptyl ), standard long stimulation protocol
- Where
- Egypt
- Volunteers
- 88 people
- Sponsor
- Kasr El Aini Hospital
Fertility Disorders, Infertility (IVF Patients)
The Effect of Mindfulness-Based Lifestyle Support Program on Infertile Women
This randomized controlled trial aimed to determine whether a mindfulness-based lifestyle support program would improve quality of life, lifestyle, mindfulness, attention and meditation level and treatment outcomes in women…
- Trial name
- NCT06799507
- Testing
- Interventions Based on Mindfulness, Routine clinical procedure
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Dokuz Eylul University
Infertility
Recombinant FSH Investigation in the Treatment of Infertility With Assisted Reproductive Technology (ART) (RITA-1)
This trial investigates the effects of FE 999049 compared to placebo.
- Trial name
- RITA-1 (NCT03740737)
- Testing
- Follitropin delta
- Where
- 23 sites in United States
- Volunteers
- 579 people
- Sponsor
- Ferring Pharmaceuticals
Infertility, Poor Responder to IVF Treatment
Study of Dehydroepiandrosterone Treatment for Poor Responders in In Vitro Fertilization Patients
The aim of this study is to show solid evidences of the efficacy of DHEA in improving the success rates of in-vitro fertilization (IVF) patients facing poor ovarian reserve.
- Trial name
- NCT01535872
- Testing
- Dehydroepiandrosterone
- Where
- Singapore
- Volunteers
- 60 people
- Sponsor
- KK Women's and Children's Hospital
Infertility, Female, Reproductive Sterility
Evaluation of Salivary ELISA for Hormone Monitoring in IVF Patients
In assisted reproductive treatment (ART), it is necessary to follow closely the stimulation cycles of patients undergoing these treatments in order to monitor the number and size of developing follicles.
- Trial name
- SALIVA_MINT (NCT05184777)
- Testing
- Determination of progesterone and oestradiol
- Where
- Spain
- Volunteers
- 120 people
- Sponsor
- Instituto Valenciano de Infertilidad, IVI VALENCIA
Female Reproductive Problem, Male Reproductive Problems
Bisphenol A Exposure, Ovarian Function and Assisted Reproductive Technology Outcome.
Our goal is to prospect the relationships between Bisphenol A (BPA) exposure (measured as its free and conjugated forms in blood and urine) and embryo implantation rate (measured as the ratio between the number of gestational…
- Trial name
- FIVPHENOL (NCT02377219)
- Testing
- hormonal and blood analysis
- Where
- 8 sites in France
- Volunteers
- 350 people
- Sponsor
- University Hospital, Toulouse
Recurrent Implantation Failure, Recurrent Pregnancy Loss
Study of Endometrial Immune and Microbiological Modifications in Cases of Recurrent Implantation Failure and/or Recurrent Pregnancy Loss
The IMERR study aims to improve understanding of certain causes of infertility related to recurrent implantation failure (RIF) and/or recurrent pregnancy loss (RPL), conditions that affect many women undergoing assisted…
- Conditions
- Recurrent Implantation Failure, Recurrent Pregnancy Loss, Infertility, Female, Endometrial Diseases
- Trial name
- IMERR (NCT07265505)
- Testing
- Endometrial Biopsy, Vaginal Swab, Blood sample
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Infertility
Randomized Trial Comparing EmbryoScope With EmbryoScope+.
The purpose of the study is to compare the current EmbryoScope Time-Lapse System being used in IVF which has become standard of care to the new model EmbryoScope to demonstrate that the EmbryoScope+ is as safe and reliable as the…
- Trial name
- NCT03522350
- Testing
- EmbryoScope, EmbryoScope+
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Weill Medical College of Cornell University
Embryo Transfer, IVF
Effect of Pentoxyfilline on Endometrial Thickness and Frozen Embryo Transfer Outcomes
The aim of this work was to investigate the effect of different vasodilators as pentoxifylline in women with unexplained infertility using IVF
- Conditions
- Embryo Transfer, IVF, Infertility
- Trial name
- NCT07499817
- Testing
- pentoxifylline 400 mg, (control)
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Beni-Suef University
Complications; Artificial Fertilization, Introduction of Embryo in Embryo Transfer
Growth Hormone (GH) in in Vitro Fertilization (IVF) Poor-responder Patients
Experimental study to evaluate if rGH addition to a standard controlled ovarian stimulation treatment improves ovarian response in women with previous poor ovarian response.
- Trial name
- FUNDEX001 (NCT01298960)
- Testing
- Somatropin
- Where
- Spain
- Volunteers
- 52 people
- Sponsor
- Fundacion Dexeus
Infertility, Weight Loss
Weight Loss on IVF Outcomes in Overweight and Obese Infertile Women
The aim of this study is to determine whether weight loss prior to in vitro fertilization (IVF) improves live birth outcomes in overweight and obese infertile women.
- Conditions
- Infertility, Weight Loss, Obesity, IVF
- Trial name
- NCT07174817
- Testing
- weight loss
- Where
- China
- Volunteers
- 197 people
- Sponsor
- Peking University People's Hospital
Androgen Receptor Gene Overexpression, Normal Responders
Androgen Receptor mRNA Expression is Positively Associated With Live Birth in Women Undergoing IVF Independently of the Type of Ovarian Response
AR is a steroid hormone receptor that regulates various genes' expression and affects cellular proliferation and differentiation.
- Conditions
- Androgen Receptor Gene Overexpression, Normal Responders, Poor Ovarian Response, Bologna Criteria
- Trial name
- NCT03433768
- Testing
- Real time PCR
- Volunteers
- 67 people
- Sponsor
- Aristotle University Of Thessaloniki
Controlled Ovarian Stimulation
A Study to Assess the Efficacy and Safety of Ganirelix (Orgalutran®) Treatment in Chinese Women Undergoing Controlled Ovarian Stimulation for in Vitro Fertilization (IVF) or Intra Cytoplasmatic Sperm Injection (ICSI) (Study 38651)(P05703)
The primary purpose of this study is to assess that ganirelix is safe and well-tolerated in Chinese women and that a controlled ovarian stimulation (COS) protocol combining recombinant follicle stimulating hormone (recFSH) with…
- Trial name
- NCT00725491
- Testing
- ganirelix, triptorelin
- Volunteers
- 259 people
- Sponsor
- Organon and Co
Infertility
The Exogenous Progesterone Free Luteal Phase After GnRHa Trigger - a Pilot Study in Normo-responder IVF Patients
After hCG trigger a large amount of exogenous progesterone is used for luteal phase support in many countries until 10th week of gestation.
- Trial name
- GnRHa trigger (NCT01980680)
- Testing
- hCG, Progesterone and Estradiol
- Where
- Denmark
- Volunteers
- 50 people
- Sponsor
- Peter Humaidan
Women Infertility
G-CSF Administration in IVF in a Preferable Preceptive Endometrium Score
This is a controlled preminary trial intended to increase the implantation rate of IVF cycles, by using more than one known procedure, endometrial scratching, evaluating the status of the adhesive factors as αVβ3 integrin…
- Trial name
- NCT03163862
- Testing
- Endometrial scratch, G-CSF administration, Saline Solution
- Volunteers
- 100 people
- Sponsor
- Istishari Arab Hospital
Infertility, Female, Pain, Postoperative
Assessing Efficacy of Intravenous Acetaminophen for Perioperative Pain Control for Oocyte Retrieval
In this research study we want to learn more about how effective certain medications are at reducing pain after oocyte (egg) retrieval surgery and how effective they are at reducing the time between the retrieval and discharge…
- Trial name
- NCT03073980
- Testing
- IV Acetaminophen, PO Acetaminophen
- Where
- United States
- Volunteers
- 161 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital