Clinical trials: IV Access
Vascular Access Complication
Prospective Feasibility Trial of AccuCath 2.25" Blood Control (BC) Placed in Difficult Access Patients in the Emergency Department
Study objective is to evaluate user preference, time for procedure, insertion success rates, complications, completion of therapy and dwell time of the AccuCath 2.25" BC device placed in difficult IV access patients in the…
- Trial name
- NCT02449798
- Testing
- AccuCath 2.25" BC Intravascular Catheter
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- C. R. Bard
Pain on Propofol IV Injection
In Children, Does Using a Synera Patch Decrease Pain When Injecting Propofol at Anesthesia Induction?
The purpose of this study is to evaluate if the Synera Patch (lidocaine/tetracaine patch), used to numb the skin before IV placement, is effective in reducing pain associated with propofol IV administration when inducing general…
- Trial name
- Synera patch (NCT01576770)
- Testing
- lidocaine/tetracaine transdermal patch (NDC 43469-864-01), Gebauer's Ethyl Chloride
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- The University of Texas Health Science Center, Houston
Orthopox Virus Infection
Tecovirimat Intravenous Treatment for Orthopox Virus Exposure
To provide a therapeutic option for patients not able to take the oral formulation of TPOXX (e.g., cannot swallow, vomiting) and who have confirmed or suspected (based on clinical signs and symptoms with known exposure while…
- Trial name
- TPOXX IV (NCT05380752)
- Testing
- TPOXX IV (Tecovirimat Injection, 10 mg/mL)
- Sponsor
- U.S. Army Medical Research and Development Command
Understanding Emergency Room Procedures
Difficult Intravenous Access Perception: Difficult IV Access - Assessment of Patient Understanding
Aim: Patient Perception: This aim broadly intends to use traditional script versus a brief video education vignette to determine understanding and preferences among general emergency department patients of rescue access…
- Trial name
- DIVA (NCT01929304)
- Testing
- Survey
- Where
- United States
- Volunteers
- 1,180 people
- Sponsor
- University of Pennsylvania
Peripheral Venous Catheterization, Difficult Intravenous Access
TruVascular Access - Ultrasound-Guided Vascular Access Study
TruVascular Access - TVA-2026 is a prospective, randomized clinical study evaluating whether ultrasound-guided peripheral vascular access improves first-attempt cannulation success compared with conventional landmark…
- Conditions
- Peripheral Venous Catheterization, Difficult Intravenous Access, Catheterization, Peripheral
- Trial name
- TVA-2026 (NCT07798427)
- Testing
- Ultrasound-Guided Peripheral Vascular Access, Standard Peripheral Vascular Access, Point-of-Care Ultrasound System for Vascular Access Guidance
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Truway Health, Inc.
Cutaneous Melanoma, Stage III, Cutaneous Melanoma, Stage IV
IFx-Hu2.0 Expanded Access Program
Expanded access requests for IFx-Hu2.0 may be considered for the treatment of adult patients (greater than or equal to 18 years of age) with stage III through IV cutaneous melanoma, advanced Merkel cell carcinoma (MCC), or…
- Conditions
- Cutaneous Melanoma, Stage III, Cutaneous Melanoma, Stage IV, Merkel Cell Carcinoma, Cutaneous Squamous Cell Carcinoma
- Trial name
- NCT04853602
- Testing
- IFx-Hu2.0
- Sponsor
- TuHURA Biosciences, Inc.
Vascular Access
Video Documentation of Localized Complications
The objective of this study is to confirm and document that with the use of a FDA Class I exempt near infrared device, VeinViewer® Vision that is hands-free and can be used for healthy adult volunteers with varying skin types to…
- Trial name
- NCT01453322
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Christie Medical Holdings, Inc.
Catheterization, Peripheral
Efficacy of Near-Infrared Vein Imaging for Difficult IV Placement
The objective of this project is to define the effectiveness and therefore the role of NIR vein finders in adult patients with difficult peripheral venous access.
- Trial name
- NCT04262947
- Testing
- Near Infrared Vein Imaging, Conventional IV placement
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Lahey Clinic
Vascular Access Complication, Ultrasound Therapy; Complications
Superior Venous Access, Midline vs Ultrasound IVs
Obtaining intravenous access (IVA) is the most common procedure performed in the emergency department (ED). Placement of IVA allows for blood work and delivery of intravenous fluids and medications.
- Trial name
- NCT03440944
- Testing
- Ultrasound Guided Peripheral IV Catheter, Midline Catheter
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Boston Medical Center
Carcinoma, Non-small-cell Lung
Iressa Expanded Access Program (EAP)
A program for patients with non small cell lung cancer who may benefit from Iressa, but cannot enter another clinical trial due to them not being eligible, or for whom no trials are available.
- Conditions
- Carcinoma, Non-small-cell Lung, Metastases, Neoplasm
- Trial name
- NCT00034879
- Testing
- ZD1839 (Gefitinib)
- Where
- 626 sites in United States
- Sponsor
- AstraZeneca
Non-Small Cell Lung Cancer
An Expanded Access Program of Tarceva (Erlotinib) in Participants With Advanced Non-Small Cell Lung Cancer (NSCLC)
This study will provide treatment with erlotinib to participants with advanced NSCLC who have received at least one course of standard chemotherapy or radiation therapy, or who are not medically suitable for either.
- Trial name
- NCT00949910
- Testing
- Erlotinib
- Where
- 543 sites in Albania, Argentina and 49 more
- Volunteers
- 6,586 people
- Sponsor
- Hoffmann-La Roche
Difficult Peripheral IV Access
Comparison of Ultrasound Guided Peripheral IV Placement With and Without Use of a Guidewire
The purpose of this study is to compare ultrasound guided peripheral IV placement with and without the use of a guidewire. Patients in the Emergency Department with difficult peripheral IV access (as defined by 2 failed attempts…
- Trial name
- NCT02422472
- Testing
- Ultrasound guided peripheral IV placement
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Brigham and Women's Hospital
Stage III (Unresectable) or Stage IV Advanced Melanoma
Expanded Access Program With Nivolumab to Treat Melanoma
The purpose of this program is to provide treatment with nivolumab to subjects with Stage III or Stage IV advanced melanoma.
- Trial name
- Checkmate 168 (NCT02142218)
- Testing
- Nivolumab
- Where
- 80 sites in United States, Argentina and 4 more
- Sponsor
- Bristol-Myers Squibb
Advanced Esophageal Squamous Cell Carcinoma, Advanced Renal Cell Carcinoma
Comparison of In-Home Versus In-Clinic Administration of Subcutaneous Nivolumab Through Cancer CARE (Connected Access and Remote Expertise) Beyond Walls (CCBW) Program
This phase II trial compares the impact of subcutaneous (SC) nivolumab given in an in-home setting to an in-clinic setting on cancer care and quality of life.
- Conditions
- Advanced Esophageal Squamous Cell Carcinoma, Advanced Renal Cell Carcinoma, Clinical Stage II Esophageal Squamous Cell Carcinoma AJCC v8, Clinical Stage IIB Cutaneous Melanoma AJCC v8
- Trial name
- NCT06265285
- Testing
- Home Health Encounter, Nivolumab, Patient Monitoring
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Mayo Clinic
IV Cannulation
Use of Vein Viewer for Insertion of Peripheral Venous Cannula in Pediatric Patients With Difficult Intravenous Access
The primary purpose of this prospective, randomized trial is successful intravenous (IV) cannulation on first attempt with the use of either the Vein Viewer (VV) or standard cannulation method.
- Trial name
- NCT00935909
- Where
- United States
- Volunteers
- 603 people
- Sponsor
- Peter Szmuk
Catheterization, Peripheral, Phlebotomy
VeinViewer for Peripheral IV Placement in Children With Difficult Intravenous (IV) Access
Hypothesis: The first attempt success rate for peripheral IV insertion for children with difficult IV access (difficult IV access [DIVA] score ≥ 4) by nurses using the VeinViewer guided technique is better than conventional…
- Trial name
- NCT00357799
- Testing
- VeinViewer
- Where
- United States
- Volunteers
- 170 people
- Sponsor
- Children's Hospital and Health System Foundation, Wisconsin
Pain
Vapocoolant Spray Used Prior to Intravenous (IV) Insertions
The primary purpose of this study is to determine if by offering a vapocoolant (cold spray) to hospital outpatients prior to an intravenous catheter (IV) insertion will increase patient satisfaction of IV insertion as well as…
- Trial name
- NCT03054740
- Testing
- Gebauer Ethyl Chloride, Nature's Tears
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Aultman Health Foundation
Hepatitis C, HIV Infections
Study to Reduce Intravenous Exposures (STRIVE)
The purpose of this study is to determine whether a six-session, small group behavioral intervention based on "peer-volunteer activism" is effective in (1) decreasing distributive sharing of syringes and other injection…
- Trial name
- NCT00391482
- Testing
- Peer Mentoring Intervention for HCV-Infected IDUs
- Where
- 3 sites in United States
- Volunteers
- 750 people
- Sponsor
- National Institute on Drug Abuse (NIDA)
Squamous Non-Small Cell Lung Cancer, Non-squamous Non-Small Cell Lung Cancer
Expanded Access Program With Nivolumab Therapy for Treatment of Advanced/Metastatic SqNSCLC or Non-SqNSCLC After One Prior Systemic Regimen
The purpose of this study is to provide treatment with nivolumab, a fully human monoclonal antibody, to subjects who have relapsed after treatment with a minimum of 1 prior systemic treatment for advanced or metastatic squamous…
- Trial name
- CheckMate 169 (NCT02475382)
- Testing
- Nivolumab
- Where
- 50 sites in Brazil, Canada
- Sponsor
- Bristol-Myers Squibb
Difficult IV Access
Ultrasound-guided Peripheral IV vs. Standard Technique in Difficult Vascular Access Patients by ICU Nurses
This is a randomized controlled single-center study that will be conducted in the intensive care unit. The main objective of this study is to assess the success rate of ultrasound-guided peripheral intravenous cannulation in ICU…
- Trial name
- NCT03745209
- Testing
- Ultrasound
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Queen's University