Clinical trials: IOL, Cataract
Cataract, Presbyopia
Comparison of Aspheric Toric Intraocular Lenses for Micro-monovision
In an aging population, cataract and presbyopia become increasingly common. A cataract is the opacification of the natural crystalline lens inside a person's eye, causing reduction of vision.
- Conditions
- Cataract, Presbyopia, Astigmatism
- Trial name
- NCT05506553
- Testing
- Intervention arm - Eyhance Toric II Intraocular Lens, Control Arm - Alcon IQ Toric Intraocular lens
- Where
- United Kingdom
- Volunteers
- 140 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Toric Intraocular Lens Stability, Visual Quality
Toric Intraocular Lens (IOL) Implantation for Management of Cataracts
This study included cataract patients who underwent toric intraocular lens (IOL) implantation, which aimed to evaluate the stability and clinical visual quality of toric IOLs.
- Trial name
- NCT05797298
- Where
- 2 sites in China
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Eye & ENT Hospital of Fudan University
Pseudoaphakia
Time Study for Biometry Measurements With the Lenstar and IntraOcularLens (IOL) Master 500
The objectives of this study are to determine the time needed to complete a full set of measurements (Total Ophthalmic Exam, Subject Data Entry and Acquisition of the Measurement) by each test device, the Lenstar 900 Version i4…
- Trial name
- NCT01550939
- Testing
- Ophthalmic Biometer
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Haag Streit USA
Cataract
Visual Outcomes and Patient Satisfaction After Bilateral Implantation of Non-diffractive EDOF IOL Made of a New Hydrophobic Acrylic Material
The objective is to measure the range of vision and patient reported visual disturbances after bilateral implantation for this unique non-diffractive extended depth of focus (EDOF) intraocular lens (IOL) made from the Clareon…
- Trial name
- NCT05488769
- Testing
- Clareon Vivity extended depth of focus (EDOF) intraocular lens
- Where
- Canada
- Volunteers
- 6 people
- Sponsor
- Thomas Nagy
Cataract, Astigmatism
A Comparison of Corneal Aberrations in Subjects With Contralateral AcrySof IQ Toric Intraocular Lens (IOL) and AcrySof IQ IOL With Limbal Relaxing Incision (LRI)
The purpose of this study was to evaluate and compare postoperative corneal aberrations and visual parameters in patients contralaterally implanted with an AcrySof IQ Toric intraocular lens (IOL) and AcrySof IQ Aspheric IOL with…
- Trial name
- NCT01045733
- Testing
- AcrySof IQ Toric IOL, AcrySof IQ Aspheric IOL, Limbal Relaxing Incision (LRI)
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Alcon Research
Cataract
Comparative Study of Three IOL Power Calculation Formulae for Asian Eyes Shorter Than 22mm or Longer Than 25mm
Implantation of an intraocular lens is the gold standard in modern day cataract surgery. The appropriate lens power needed to achieve the desired refractive outcome can be calculated with a whole variety of formulas.
- Trial name
- NCT00347516
- Testing
- IOL calculation formula
- Where
- Singapore
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Singapore National Eye Centre
Cataract
Symfony vs Vivity in Dim Light
The purpose of this study is to evaluate the visual outcomes of the Symfony lens and the Vivity lens under mesopic lighting conditions in adult patients undergoing routine cataract surgery.
- Trial name
- NCT06229106
- Testing
- Symfony IOL, Vivity IOL
- Where
- 2 sites in United States
- Volunteers
- 64 people
- Sponsor
- Carolina Eyecare Physicians, LLC
Cataract
Visual and Refractive Outcomes After Implantation of Aspheric IOLs With Different Dioptric Increments and Manufacturing
This study compares two intraocular lenses, the Softec HD and the Tecnis Z9002, used to replace the natural crystalline lens after cataract extraction.
- Trial name
- NCT01249144
- Testing
- Intraocular Lens (IOL)
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Lenstec Incorporated
Cataract Senile
Precisight® Intraocular Lens Implantation for Cataract Treatment
The purpose of this study is to determine the refractive outcomes and optimize the clinical features of a new intraocular lens intended to treat the senile cataract.
- Trial name
- PEACE (NCT02970487)
- Testing
- Intraocular implant of the Precisight
- Where
- Philippines
- Volunteers
- 96 people
- Sponsor
- InfiniteVision Optics
Cataracts, Cataract Surgery
Endothelial Cell Loss and Induced Astigmatism After Wound-directed and Wound-assisted IOL Injection
The purpose of this study is to determine if there is any difference in astigmatism (eye surface curvature) or corneal endothelial cell density (the inner cell lining of the eye surface) after two different methods for inserting…
- Trial name
- NCT01250964
- Testing
- Lens insertion during cataract surgery
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- University of North Carolina, Chapel Hill
Cataract
Lenstec Tetraflex Accommodating Posterior Chamber Intraocular Lens (IOL) Clinical Investigation
The purpose of the following clinical protocol is to evaluate the safety and effectiveness of the Lenstec Tetraflex Accommodating Posterior Chamber Intraocular Lens (IOL) for the protocol inclusion/exclusion criteria.
- Trial name
- NCT00969371
- Testing
- posterior chamber IOL implantation, Experimental TetraFlex Study IOL
- Volunteers
- 470 people, healthy volunteers welcome
- Sponsor
- Lenstec Incorporated
Age-Related Macular Changes, Age-Related Macular Degeneration
Effects of Sun Filters on Age-related Macular Degeneration in People With Lens Implants
This study will test a new method for preventing worsening of age-related macular degeneration (AMD) and for developing imaging methods to follow the very earliest microscopic changes in the disease.
- Conditions
- Age-Related Macular Changes, Age-Related Macular Degeneration, Cataract and IOL Surgery, Retinal Photochemistry
- Trial name
- NCT00487838
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Cataract
Safety and Efficacy of Iontophoretic Dexamethasone Phosphate Delivery Prior to Implantation of a Posterior Chamber IOL
The purpose of this study is to evaluate the safety and efficacy of ocular iontophoresis with dexamethasone phosphate ophthalmic solution EGP-437 using the EyeGate® II Drug Delivery System (EGDS) compared to placebo in patients…
- Trial name
- NCT01602068
- Testing
- Dexamethasone Phosphate Ophthalmic, 100 mM Sodium Citrate Buffer
- Where
- 3 sites in United States
- Volunteers
- 45 people
- Sponsor
- Eyegate Pharmaceuticals, Inc.
Cataract, Lens Opacities
Visual Performance Intraocular Lens (IOL) MicroPure 1.2.3.
The clinical investigation is a post-market clinical follow up study whereby patients undergoing routine cataract surgery will have monolateral implantation of a commercially available, CE approved monofocal intraocular lens…
- Trial name
- NCT03297372
- Testing
- IOL implantation
- Where
- 2 sites in Italy
- Volunteers
- 121 people
- Sponsor
- Beaver-Visitec International, Inc.
Cataract
Surgeon Experience ReSTOR A +4 Intraocular Lens (IOL)
To collect visual outcome data post AcrySof ReSTOR Aspheric +4 implantation from surgeons throughout the United States.
- Trial name
- NCT00733512
- Testing
- ReSTOR
- Where
- United States
- Volunteers
- 146 people
- Sponsor
- Alcon Research
Glaucoma, Cataract
Observational Study to Evaluate Long Term Outcomes for Ocular Hypertension and Glaucoma Patients Treated With the SpyGlass Bimatoprost Implant System / IOL Combination
The goal of this clinical trial is to further observe and learn if the SpyGlass Pharma Bimatoprost Implant System / IOL Combination works to treat cataracts and either ocular hypertension or glaucoma.
- Conditions
- Glaucoma, Cataract, Ocular Hypertension
- Trial name
- NCT07154810
- Where
- Honduras
- Volunteers
- 23 people
- Sponsor
- SpyGlass Pharma, Inc.
Cataract, Healthy Eye
The Heidelberg Engineering ANTERION Anterior Segment Cornea and IOL Precision and Agreement Study
This is a prospective clinical study that will be conducted at one clinical site located in the United States to assess anterior segment parameters with the ANTERION
- Conditions
- Cataract, Healthy Eye, Cornea Abnormality, Post-Keratorefractive Surgery
- Trial name
- NCT04130490
- Testing
- ANTERION
- Where
- United States
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- Heidelberg Engineering GmbH
Bilateral Cataract
Pilot Study With a Diffractive Trifocal IOL (POD AY 26P FineVision)
The principal objective of the study is to determine the visual acuity at far, intermediate and near distances tested with optotypes at different distances from the eyes and tested with defocus addition lenses of patients…
- Trial name
- NCT02042755
- Testing
- trifocal intraocular lens
- Where
- Israel
- Volunteers
- 19 people
- Sponsor
- Beaver-Visitec International, Inc.
IOL, Cataract
Clinical Outcomes of Patients with LAL+ in At Least One Eye
The objective of this study is to collect data on bilateral pseudophakic patients implanted with the RxSight Light Adjustable Lens+ (LAL+) in at least one eye
- Trial name
- NCT06650358
- Testing
- Light Adjustable Lens+
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Frank A. Bucci, Jr., M.D.
Cataract
Spectacle Independence and Overall Satisfaction With AcrySof® Panoptix® Toric Intraocular Lens
The study was designed to assess the spectacle independence and satisfaction of patients receiving the AcrySof® Panoptix® Toric intraocular lens (IOL) after uneventful cataract surgery.
- Trial name
- NCT04128514
- Testing
- Panoptix Toric
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Eye Center of North Florida