Clinical trials: IOL, Cataract
The Comparison of IOL Formulas in Eyes With PCE≥15um Undergoing Cataract Surgery
Comparison of IOL Formulas in Eyes With PCE≥15µm
The goal of this observational study is to evaluate the long-term refractive outcomes of advanced intraocular lens (IOL) power calculation formulas in cataract patients with posterior corneal elevation (PCE ≥ 15 μm).
- Trial name
- NCT07346456
- Testing
- Intraocular lens calculation formulas
- Where
- China
- Volunteers
- 102 people
- Sponsor
- Second Affiliated Hospital of Xi'an Jiaotong University
Cataract
Intraocular Lens (IOL) Calculation Improvement
Intraocular Lens (IOL) formulas sometimes differ from expected. Using novel measurement methods before and after cataract surgery improved formulas are tried be developed.
- Trial name
- NCT01372657
- Testing
- biometry calculation
- Where
- Switzerland
- Volunteers
- 11 people
- Sponsor
- University Hospital, Basel, Switzerland
High Myopia, Capsular Tension Ring
Influence of Capsular Tension Ring on IOL-capsular Complex After Cataract Surgery in Patients With High Myopia: a Clinical Observation Based on SS-OCT
The IOL-capsular complex is formed after cataract surgery and intraocular lens (IOL) implantation.Early postoperative mechanical wrapping of the anterior and posterior capsules plays a significant role in preventing IOL…
- Trial name
- NCT05095194
- Testing
- Cataract surgery with IOL implantation and with/without capsular tension ring implatation
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Wenzhou Medical University
Cataract
The Clareon PanOptix Trifocal IOL: Visual Outcomes and Patient Satisfaction
This will be a single arm, open-label, prospective study of patient-reported outcomes of patients with bilateral implantation of the Panoptix or Panoptix Toric implant.
- Trial name
- NCT05346172
- Testing
- PanOptix or PanOptix Toric IOL
- Where
- 3 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Research Insight LLC
Cataract
Clinical Performance of the Asqelio™ Trifocal Diffractive Intraocular Lens
The goal of this observational study is to evaluate whether the Asqelio™ Trifocal intraocular lens (IOL) can improve refractive outcomes and optical quality in patients (aged ≥45 years) undergoing cataract surgery or clear lens…
- Trial name
- NCT06935565
- Testing
- Trifocal IOL implantation
- Where
- Spain
- Volunteers
- 30 people
- Sponsor
- AST Products, Inc.
Endothelial Cell Loss, Corneal, Cataract and Intraocular Lens (IOL) Surgery
Effect of Vitamin C Supplementation in Corneal Endothelial Damage in Phacoemulsification of Patients with Hard Cataracts
The goal of this clinical trial is to analyze the protective effects of oral ascorbic acid on the corneal endothelial layer undergoing oxidative stress due to phacoemulsification in patients with hard cataracts.
- Trial name
- NCT06781970
- Testing
- Oral Vitamin C
- Where
- 2 sites in Indonesia
- Volunteers
- 120 people
- Sponsor
- Universitas Indonesia
Cataract, Aphakia
Clareon Toric vs Eyhance Toric
The primary purpose of this study is to compare the Clareon/Clareon Toric Intraocular Lenses (IOLs) to the Eyhance/Eyhance Toric IOLs in binocular Best Corrected Distance Visual Acuity (BCDVA) at 3 months postoperative.
- Trial name
- NCT05481125
- Testing
- Clareon IOL, Clareon Toric IOL, Eyhance IOL
- Where
- 8 sites in United States
- Volunteers
- 203 people
- Sponsor
- Alcon Research
High Myopia, Cataract
Visual Performance of Functional Intraocular Lenses in Cataracts
This is a prospective, multi-center, randomized comparative study. The purpose of the study is to evaluate and compare the postoperative visual outcomes and quality of vision of two diffractive trifocal intraocular lenses (IOLs)…
- Trial name
- NCT05581888
- Testing
- trifocal intraocular lens
- Where
- China
- Volunteers
- 62 people
- Sponsor
- Eye & ENT Hospital of Fudan University
Cataract
Optimizing the Assessment of Refractive Outcomes After Cataract Surgery
The purpose of this study is to evaluate current available assessments (automated vs. manual) with which manifest refraction data and biometric variables are obtained to understand if data from an automated refractor can be…
- Trial name
- NCT02842151
- Testing
- Manifest refraction, ACRYSOF® IQ Monofocal IOL Model SN60WF, Topcon® KR-1W Wave-Front Analyzer
- Volunteers
- 162 people
- Sponsor
- Alcon Research
Cataract Senile
The Effect of LASIK on the Calibration of IOL Formula Calculation: a Comparative Study
Direct comparison study between previous LASIK or non-LASIK cataract eyes, the performance between non-LASIK and LASIK patients were (i) Ophthalmic examinations: UDVA, CDVA and uncorrected near visual acuity (UNVA) (40cm) and…
- Trial name
- NCT06165796
- Testing
- routine cataract surgery and intraocular lens implantation
- Where
- Taiwan
- Volunteers
- 331 people
- Sponsor
- Taipei Nobel Eye Clinic
Cataract
Clinical Investigation of the AcrySof® IQ PanOptix™ IOL
The purpose of this study is to evaluate the effectiveness and safety of the AcrySof® IQ PanOptix™ Intraocular Lens (IOL) Model TFNT00 when implanted to replace the natural lens following cataract removal.
- Trial name
- NCT03090256
- Testing
- AcrySof® IQ PanOptix™ IOL
- Where
- 2 sites in Japan
- Volunteers
- 76 people
- Sponsor
- Alcon Research
Cataract
Rotational Stability of Acrysof IQ Vivity Extended Vision Toric IOL and Refractive Visual Outcome.
The purpose of this research is to assess the rotational stability of the AcrySof IQ Vivity Extended Vision Toric IOL and Refractive Visual outcome.
- Trial name
- NCT05119127
- Testing
- Alcon Vivity toric intra ocular lens
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Kevin Barber
Cataract
A Clinical Investigation of the ClarVista HARMONI™ Modular Intraocular Lens Implant Following Cataract Surgery
The main objectives of this feasibility study were: To demonstrate the feasibility of HARMONI Modular Intraocular Lens (HMIOL) implantation and assembly in subjects undergoing cataract surgery (All HMIOL Cohort), and To…
- Trial name
- NCT02521766
- Testing
- Harmoni Modular Intraocular Lens, Commercially Available Intraocular Lens, Optic exchange
- Where
- 2 sites in New Zealand, Philippines
- Volunteers
- 217 people
- Sponsor
- ClarVista Medical
Cataract, Presbyopia
Prospective Clinical Trial of Unilateral or Bilateral Implantation of TecnisSymfony IOL in Cataract Patients With Presbyopia
This is to evaluate the satisfaction of patient and physician about short-distance, medium-distance, long-distance postoperative vision and eyeglass dependence, glare, and visual acuity after insertion of the TECNIS® Symfony or…
- Trial name
- NCT03501654
- Testing
- TecnisSymfony®
- Where
- South Korea
- Volunteers
- 20 people
- Sponsor
- Seoul National University Hospital
Cataract, Aphakia
Visual and Refractive Outcomes of The ClarVista HARMONI™ Modular Intraocular Lens System (HMIOL)
The purpose of this study was to evaluate visual and refractive outcomes with the use of the HARMONI™ Modular Intraocular Lens (HMIOL) System implantation, assembly, and optic exchange in subjects undergoing cataract surgery.
- Trial name
- NCT03681886
- Testing
- Harmoni Modular Intraocular Lens, Optic Exchange
- Volunteers
- 150 people
- Sponsor
- ClarVista Medical
Patients Having Undergone Unilateral Cataract Extraction and Implantation of a Monofocal
OPEN-LABEL, MULTI-CENTER, PHASE 1b/2a CLINICAL TRIAL DESIGNED TO EVALUATE THE SAFETY AND EFFICACY OF IONTOPHORETIC DEXAMETHASONE PHOSPHATE OPHTHALMIC SOLUTION IN PATIENTS HAVING UNDERGONE CATARACT SURGERY WITH IMPLANTATION OF A POSTERIOR CHAMBER INTRAOCULAR LENS (IOL)
To evaluate the safety and efficacy of ocular iontophoresis with dexamethasone phosphate ophthalmic solution, EGP-437®, using the EyeGate® II Drug Delivery System (EGDS) in patients having undergone cataract surgery with…
- Trial name
- NCT02571556
- Testing
- Experimental: Dexamethasone Phosphate Ophthalmic solution (40 mg/mL) delivered by ocular iontophoresis consisting of 4.0 mA-min at 1.5 mA
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Eyegate Pharmaceuticals, Inc.
Eye Disorders, Cataract Extraction
Effectiveness of a Large Language Model-Based Educational Tool on Intraocular Lens Options
Patients with cataracts disease need to choose what type of artificial lens will go into their eye prior to surgery date. Some lenses are standard and are usually covered by insurance.
- Conditions
- Eye Disorders, Cataract Extraction, Cataract and IOL Surgery, Cataract Surgery Experience
- Trial name
- NCT07317661
- Testing
- LLM-based Education
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Stanford University
Cataract, IOL
Visual Outcomes With a Trifocal IOL in Subjects With Open-angle Glaucoma
This study will examine the visual outcomes of subjects undergoing cataract surgery and minimally invasive glaucoma surgery with the implantation of a trifocal intraocular lens.
- Conditions
- Cataract, IOL, Glaucoma, Open-Angle
- Trial name
- NCT04619654
- Testing
- Cataract surgery with implantation of trifocal IOL combined with trabecular scaffold
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Vold Vision P.L.L.C
Cataract
AMO's Tecnis™ Multifocal Intraocular Lenses (Tecnis MF), Alcon's ReStor Multifocal IOL
The purpose of this study is to compare the visual outcomes with bilateral implantation of Tecnis MF and ReSTOR IOLs Six months post cataract surgery.
- Trial name
- NCT01278420
- Testing
- Tecnis MF, ReSTOR
- Where
- 6 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Innovative Medical
Cataract
Post-Approval Study of the Tecnis® Toric IOL
This study is a prospective, multicenter, bilateral, non-randomized, open-label, comparative clinical study conducted at up to 80 sites in the USA.
- Trial name
- NCT02566083
- Testing
- non-toric intraocular lens, toric intraocular lens
- Where
- 44 sites in United States
- Volunteers
- 365 people
- Sponsor
- Abbott Medical Optics