Clinical trials: IOL, Cataract
Aphakia
Feasibility Study of an Accommodating IOL Design
The purpose of this clinical study is to assess safety and explore usability and effectiveness of the test product, AAL-FAIOL. This study will be conducted in Central America.
- Trial name
- NCT07147192
- Testing
- AAL-FAIOL, BAL-FAIOL, Phacoemulsification
- Where
- 4 sites in Costa Rica, Dominican Republic and 2 more
- Volunteers
- 85 people
- Sponsor
- Alcon Research
Posterior Capsule Opacification
Posterior Capsule Opacification Following Cataract Surgery With Implantation of the MICS IOL L313
This study collects intra- and postoperative data from the patients´charts retrospectively and evaluates retro- and prospectively the rate of posterior capsule opacification (PCO) following implantation of the intraocular lens L…
- Trial name
- NCT03184428
- Testing
- Postoperative observation and survey
- Where
- Germany
- Volunteers
- 3,785 people
- Sponsor
- Dietrich-Bonhoeffer-Klinikum
Cataract
Clinical Evaluation of the One-Piece Tecnis Multifocal Intraocular Lens (IOL)
The purpose of this study is to evaluate near vision of the One-Piece Tecnis Multifocal lens (ZMB00) vs. the One-piece Tecnis monofocal lens (ZCB00)and additionally evaluate general postoperative outcomes of the One-Piece Tecnis…
- Trial name
- NCT01210807
- Testing
- One-Piece Tecnis Multifocal IOL, One-Piece Tecnis monofocal IOL, Model ZCB00
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Abbott Medical Optics
Astigmatism
Evaluation of Visual Acuity of the Envista One-piece Acrylic Toric IOL MX60ET
The primary objective of this study is to evaluate rotational stability and functional improvements in visual acuity of the enVista monofocal Toric IOL (MX60ET) following cataract surgery.
- Trial name
- NCT05739656
- Testing
- CATARACT SURGERY
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Bausch & Lomb Incorporated
Cataract
Blue Light Intraocular Lenses (IOLs) and Photostress
To determine what effect a blue light filtering Intraocular Lens (IOL) has on macular pigment levels.
- Trial name
- NCT00710996
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Alcon Research
Cataract, Corneal Astigmatism
Evaluation of the Rotational Stability of the Tecnis Toric II IOL
This is a prospective, multicenter, single-arm, open-label clinical study of the commercially available TECNIS Toric II IOL. The study will be conducted in up to 192 subjects needing unilateral or bilateral cataract surgery in up…
- Trial name
- STEELE (NCT04327518)
- Testing
- TECNIS® Toric II
- Where
- 7 sites in United States
- Volunteers
- 125 people
- Sponsor
- Johnson & Johnson Surgical Vision, Inc.
Cataracts
Visual Function Evaluation of Bilateral AcrySof ReSTOR Aspheric IOL
The objective of this study is to evaluate postoperative visual function in patients implanted bilaterally with the ReSTOR Aspheric Intraocular Lens (IOL).
- Trial name
- NCT00818116
- Testing
- AcrySof ReSTOR Aspheric IOL
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- Alcon Research
Subjects Undergoing Cataract Surgery and Insertion of IOL
Clinical Evaluation of TrueVision System: LRI and Capsulorhexis Templates
To evaluate the ability of the TRUEVISION 3D VISUALIZATION AND GUIDANCE SYSTEM FOR MICROSURGERY to provide the ophthalmic surgeon appropriate alignment, orientation and sizing information during cataract or refractive lens…
- Trial name
- NCT01123343
- Testing
- TrueVision 3D Visualization and Guidance System for MicroSurgery
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- TrueVision Systems, Inc
Eye Diseases, Postcataract Aphakia
Investigation of the Safety and Effectiveness of Monofocal Toric Intraocular Lens (IOL)
This study is a prospective, multicenter, randomized, double masked trial comparing an investigational Monofocal Toric intraocular lens (IOL) (PODEYE TORIC CYL 1.5 D) and a commercially available non-toric monofocal IOL.
- Conditions
- Eye Diseases, Postcataract Aphakia, Cataract, Lens Opacities
- Trial name
- NCT06399211
- Testing
- PODEYE TORIC Monofocal IOL, Alcon AcrySof SA60AT Monofocal IOL
- Volunteers
- 261 people
- Sponsor
- Beaver-Visitec International, Inc.
Cataract Senile
Extended Depth of Focus (EDF) Intraocular Lens (IOL) Versus Monofocal Intracoular Lens (IOL)
Extended depth of focus (EDF) intraocular lens (IOL) versus Monofocal intraocular lens (IOL)
- Trial name
- NCT07092020
- Testing
- EDF, Monofocal IOL
- Where
- 14 sites in Bulgaria, Czechia and 2 more
- Volunteers
- 220 people
- Sponsor
- Carl Zeiss Meditec AG
Cataract, Glaucoma
Evaluation of the Safety and Efficacy of the Bimatoprost Implant System Used in Combination With the SpyGlass IOL Compared to Timolol Ophthalmic Solution (Rhine)
This trial is a randomized study to evaluate the Bimatoprost Implant System used in combination with the SpyGlass IOL to Timolol Ophthalmic Solution in participants with mild to moderate open-angle glaucoma or ocular hypertension…
- Conditions
- Cataract, Glaucoma, Ocular Hypertension
- Trial name
- NCT07218783
- Testing
- Bimatoprost Implant System, SpyGlass IOL, Timolol Maleate Ophthalmic Solution, 0.5%
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- SpyGlass Pharma, Inc.
Cataracts
Clinical Investigation of Visual Function After Bilateral Implantation of Two Presbyopia-Correcting Trifocal Intraocular Lenses (IOL)
The purpose of this study is to clinically evaluate the visual performance of two commercially available presbyopia-correcting Trifocal IOLs.
- Trial name
- NCT02691741
- Testing
- AcrySof® IQ PanOptix™ Presbyopia-Correcting IOL, AT LISA® tri IOL
- Volunteers
- 215 people
- Sponsor
- Alcon Research
Aphakia, Postcataract, Cataract; Eye Disease
Safety and Efficacy of a Trifocal Intraocular Lens (IOL) POD L GF in Comparison With a Multifocal and a Monofocal IOL
The objectives of the Post-Market Follow-up (PMCF) clinical investigation are to determine the safety and performance of a hydrophobic trifocal intraocular lens POD L GF in comparison with two comparator lenses: another…
- Trial name
- NCT04005651
- Testing
- POD L GF IOL, Symfony® IOL, AcrySof® IOL
- Where
- 5 sites in France, Germany and 1 more
- Volunteers
- 100 people
- Sponsor
- Beaver-Visitec International, Inc.
Aphakia Cataract
Clinical Evaluation of the Adaptilens Accommodating IOL
The goals of this feasibility study are to learn more about the performance of the intraocular lens (IOL), if the IOL is safe for use, and what the best surgical techniques are for implanting the IOL in patients who require…
- Trial name
- NCT07607860
- Testing
- Accomodating Intra Ocular Lens, Monofocal Intra Ocular Lens
- Volunteers
- 100 people
- Sponsor
- Adaptilens, Inc.
Cataract Senile
Study to Optimize the IOL Constant of a New Multifocal Intraocular Lens
Prospective, non-comparative, multicenter study on medical device with 6 months follow-up.
- Trial name
- HECATE A (NCT05201027)
- Testing
- trifocal intraocular lens
- Where
- El Salvador
- Volunteers
- 52 people
- Sponsor
- Carl Zeiss Meditec AG
Cataract
Trial Following Subjects Bilaterally Implanted With Mini Well Ready For 2 Years After the Second Eye Implant
The study objective is to evaluate the visual performance of MINI WELL Ready at 24 months following the second eye implant. The objectives of safety are to evaluate the rate of Secondary Surgical Interventions related to the…
- Trial name
- NCT04801992
- Testing
- MINI WELL Ready (SIFI SpA, Italy)
- Where
- Italy
- Volunteers
- 23 people
- Sponsor
- SIFI SpA
Cataracts
Contralateral ReSTOR / Monofocal or Phakic Eye
Bilateral evaluation of unilateral implantation of ReSTOR and contralateral monofocal or phakic eye.
- Trial name
- NCT00731640
- Testing
- ReSTOR
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- Alcon Research
Cataract, Lens Opacities
PMCF Retrospective Study Outcomes of a Monofocal Toric Intraocular Lens
This is a monocentric retrospective, open-label clinical study in patients after unilateral or bilateral implantation of hydrophobic acrylic monofocal toric intraocular lens PODEYE TORIC and executed only with standard of care…
- Conditions
- Cataract, Lens Opacities, Astigmatism
- Trial name
- NCT05055076
- Testing
- PODEYE TORIC
- Where
- France
- Volunteers
- 105 people
- Sponsor
- Beaver-Visitec International, Inc.
Cataract
Comparison of Gemini III Rev 2 Implanted in Conjunction With an Approved IOL vs Eyes Implanted With an Approved IOL
This study is a prospective, observational, randomized, controlled, paired eye, subject-masked design.
- Trial name
- NCT04059796
- Testing
- Omega Gemini III Rev 2 Device, Control Eye
- Where
- Costa Rica
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Omega Ophthalmics
Cataract
Observational, Prospective Clinical Investigation on Mini 4 Ready Intraocular Lens
Cataract surgery presents an extremely high success rate in improving vision and quality of life and it is currently the most commonly performed ophthalmic surgery, especially considering its growing utility in the aging…
- Trial name
- NCT06093880
- Testing
- monofocal intraocular lens
- Where
- Italy
- Volunteers
- 125 people
- Sponsor
- SIFI SpA