Clinical trials: IOL, Cataract
Cataract
Visual and Refractive Outcomes After Implantation of Aspheric IOLs With Different Dioptric Increments and Manufacturing
This study compares two intraocular lenses, the Softec HD and the Tecnis Z9002, used to replace the natural crystalline lens after cataract extraction.
- Trial name
- NCT01249144
- Testing
- Intraocular Lens (IOL)
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Lenstec Incorporated
Cataract Senile
Precisight® Intraocular Lens Implantation for Cataract Treatment
The purpose of this study is to determine the refractive outcomes and optimize the clinical features of a new intraocular lens intended to treat the senile cataract.
- Trial name
- PEACE (NCT02970487)
- Testing
- Intraocular implant of the Precisight
- Where
- Philippines
- Volunteers
- 96 people
- Sponsor
- InfiniteVision Optics
Cataract
Lenstec Tetraflex Accommodating Posterior Chamber Intraocular Lens (IOL) Clinical Investigation
The purpose of the following clinical protocol is to evaluate the safety and effectiveness of the Lenstec Tetraflex Accommodating Posterior Chamber Intraocular Lens (IOL) for the protocol inclusion/exclusion criteria.
- Trial name
- NCT00969371
- Testing
- posterior chamber IOL implantation, Experimental TetraFlex Study IOL
- Volunteers
- 470 people, healthy volunteers welcome
- Sponsor
- Lenstec Incorporated
Cataract
Safety and Efficacy of Iontophoretic Dexamethasone Phosphate Delivery Prior to Implantation of a Posterior Chamber IOL
The purpose of this study is to evaluate the safety and efficacy of ocular iontophoresis with dexamethasone phosphate ophthalmic solution EGP-437 using the EyeGate® II Drug Delivery System (EGDS) compared to placebo in patients…
- Trial name
- NCT01602068
- Testing
- Dexamethasone Phosphate Ophthalmic, 100 mM Sodium Citrate Buffer
- Where
- 3 sites in United States
- Volunteers
- 45 people
- Sponsor
- Eyegate Pharmaceuticals, Inc.
Cataract, Lens Opacities
Visual Performance Intraocular Lens (IOL) MicroPure 1.2.3.
The clinical investigation is a post-market clinical follow up study whereby patients undergoing routine cataract surgery will have monolateral implantation of a commercially available, CE approved monofocal intraocular lens…
- Trial name
- NCT03297372
- Testing
- IOL implantation
- Where
- 2 sites in Italy
- Volunteers
- 121 people
- Sponsor
- Beaver-Visitec International, Inc.
Cataract
Surgeon Experience ReSTOR A +4 Intraocular Lens (IOL)
To collect visual outcome data post AcrySof ReSTOR Aspheric +4 implantation from surgeons throughout the United States.
- Trial name
- NCT00733512
- Testing
- ReSTOR
- Where
- United States
- Volunteers
- 146 people
- Sponsor
- Alcon Research
Glaucoma, Cataract
Observational Study to Evaluate Long Term Outcomes for Ocular Hypertension and Glaucoma Patients Treated With the SpyGlass Bimatoprost Implant System / IOL Combination
The goal of this clinical trial is to further observe and learn if the SpyGlass Pharma Bimatoprost Implant System / IOL Combination works to treat cataracts and either ocular hypertension or glaucoma.
- Conditions
- Glaucoma, Cataract, Ocular Hypertension
- Trial name
- NCT07154810
- Where
- Honduras
- Volunteers
- 23 people
- Sponsor
- SpyGlass Pharma, Inc.
Cataract, Healthy Eye
The Heidelberg Engineering ANTERION Anterior Segment Cornea and IOL Precision and Agreement Study
This is a prospective clinical study that will be conducted at one clinical site located in the United States to assess anterior segment parameters with the ANTERION
- Conditions
- Cataract, Healthy Eye, Cornea Abnormality, Post-Keratorefractive Surgery
- Trial name
- NCT04130490
- Testing
- ANTERION
- Where
- United States
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- Heidelberg Engineering GmbH
Bilateral Cataract
Pilot Study With a Diffractive Trifocal IOL (POD AY 26P FineVision)
The principal objective of the study is to determine the visual acuity at far, intermediate and near distances tested with optotypes at different distances from the eyes and tested with defocus addition lenses of patients…
- Trial name
- NCT02042755
- Testing
- trifocal intraocular lens
- Where
- Israel
- Volunteers
- 19 people
- Sponsor
- Beaver-Visitec International, Inc.
Cataracts
Low Cylinder Toric
Study evaluates the visual outcomes and patient satisfaction after implantation of a toric intraocular lens (IOL).
- Trial name
- NCT00732030
- Testing
- Toric IOL (SN60T3)
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Alcon Research
Cataracts
Clinical Investigation of Corneal Incision Size After Intraocular Lens (IOL) Implantation
The purpose of this study is to compare corneal incision size after IOL implantation with the use of one of four IOL delivery systems (three preloaded IOL delivery systems and one manually loaded IOL delivery system).
- Trial name
- NCT02826421
- Testing
- UltraSert Preloaded Delivery System, iTec Preloaded Delivery System, iSert Preloaded Delivery System
- Volunteers
- 114 people
- Sponsor
- Alcon Research
Cataract
Toric Performance And Constant Evaluation
The main purpose of this investigation is to support safety and performance assessment of the investigational device with a focus on optimizing the IOL constants based on refractive outcomes.
- Trial name
- PACE (NCT07471295)
- Testing
- Monofocal toric IOL
- Where
- 6 sites in Czechia, Germany and 2 more
- Volunteers
- 130 people
- Sponsor
- Carl Zeiss Meditec AG
Cataract, Lens Opacities
Clinical Study to Investigate Outcomes of Trifocal Toric IOL POD FT in Asian Eyes
Prospective, controlled, single-surgeon, single-center clinical study to compare visual acuity outcomes to data obtained in a similar study by the same principal investigator on the trifocal IOL POD F (study no.
- Conditions
- Cataract, Lens Opacities, Presbyopia
- Trial name
- NCT03844828
- Testing
- IOL implantation experimental
- Where
- Philippines
- Volunteers
- 100 people
- Sponsor
- Beaver-Visitec International, Inc.
Aphakia
Clinical Investigation of the AcrySof IQ Vivity Extended Vision Intraocular Lens (IOL)
The purpose of this study is to compare the visual disturbance profile of an intraocular lens (IOL) using nondiffractive optics, the VIVITY IOL, to two diffractive IOLs in subjects requiring bilateral cataract surgery.
- Trial name
- NCT04098367
- Testing
- VIVITY, SYMFONY, AT LARA
- Where
- 12 sites in Australia, New Zealand
- Volunteers
- 222 people
- Sponsor
- Alcon Research
Cataracts
Clinical Investigation of AcrySof® IQ ReSTOR® +2.5 D Multifocal Intraocular Lens (IOL) Model SN6AD2 [SV25T0]
The purpose of this study is to compare the safety and efficacy of an investigational multifocal intraocular lens (IOL) to an FDA-approved monofocal IOL.
- Trial name
- NCT01510717
- Testing
- AcrySof® IQ ReSTOR® +2.5 D Multifocal IOL Model SN6AD2 [SV25T0], AcrySof® IQ Monofocal IOL Model SN60WF
- Volunteers
- 409 people
- Sponsor
- Alcon Research
Cataract
Safety and Efficacy of the Bi-Aspheric Monofocal IOL
This is an observational, single-center, non-control, open-label post-marketing study. Patients implanted with an aspicio™ Monofocal Intraocular Lens will be scheduled for a follow-up visit at least 3 months after the surgery to…
- Trial name
- NCT06380478
- Testing
- aspicio Monofocal IOL
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- ICARES Medicus, Inc.
Astigmatism
Visual Performance With Clareon® Vivity® Intraocular Lenses (IOLs)
The purpose of this study is to generate clinical data to quantify the impact of residual astigmatism on the overall visual performance during distance, intermediate, and near viewing in patients implanted with Clareon Vivity…
- Trial name
- NCT06784063
- Testing
- Clareon Vivity Extended Vision IOL
- Where
- 3 sites in United States
- Volunteers
- 40 people
- Sponsor
- Alcon Research
Cataract
Clinical Outcome After Implantation of Medicontur Liberty 677MTY, a Multifocal, Toric IOL
The purpose of this study is to evaluate visual outcomes, patient satisfaction and YAG capsulotomy rate after implantation of a multifocal toric lens- Liberty 677MTY - manufactured by Medicontur Ltd. (Zsámbék, Hungary),
- Trial name
- NCT04670237
- Testing
- Liberty677MTY Multifocal Toric IOL
- Where
- Hungary
- Volunteers
- 30 people
- Sponsor
- Medicontur Medical Engineering Ltd
Cataract
Visual Outcome and Visual Quality After Bilateral Implantation of the AcrySof® IQ IOL Compared to MI60® and Tecnis® IOL
The objective of the study is to compare the visual outcomes of three aspheric monofocal intraocular lenses after cataract surgery - ACRYSOF® IQ, Tecnis® and Akreos® MI60.
- Trial name
- NCT00760058
- Testing
- AcrySof® IQ IOL, Tecnis® Aspheric intraocular lens, Akreos® MI60 intraocular lens
- Where
- United States
- Sponsor
- Alcon Research
Eye Diseases, Postcataract Aphakia
Investigation of the Safety and Effectiveness of a Trifocal IOL
This study is a prospective, multicenter, randomized, double masked confirmatory trial comparing an investigational trifocal intraocular lens (IOL) and a commercially available monofocal IOL.
- Conditions
- Eye Diseases, Postcataract Aphakia, Cataract, Lens Opacities
- Trial name
- NCT04176965
- Testing
- FINEVISION HP IOL, Alcon AcrySof SN60AT
- Where
- 20 sites in United States
- Volunteers
- 539 people
- Sponsor
- Beaver-Visitec International, Inc.