Clinical trials: ICU
Lung Microbiota
Lung Microbiota Analysis in Critically Ill Patients Admitted to the Intensive Care Unit.
Our study aims to evaluate the relationship between the heterogeneity of pulmonary microbiota and clinical and outcome variables among critically ill patients admitted to the intensive care unit (ICU).
- Trial name
- NCT04271345
- Where
- Italy
- Volunteers
- 150 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Pain Management
Non-Pharmacological Nursing Pain Management for Preterm Infants
A randomized controlled trial will be conducted to examine the effect of non-pharmacological nursing pain management strategies in alleviating pain among preterm infants.
- Trial name
- NCT05947877
- Testing
- Non-pharmacological pain management strategies
- Where
- Iraq
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- University of Baghdad
Hyperactive Delirium, Mixed Delirium
Valproic Acid for Treatment of Hyperactive or Mixed Delirium in ICU
Delirium is the most often encountered psychiatric diagnosis in the general hospital, with incidence up to 85% in the intensive care unit (ICU) setting and with significant consequences on patients' morbidity and mortality.
- Trial name
- NCT02343575
- Testing
- Valproic Acid, Haloperidol
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Stanford University
Bronchiolitis
Intrapulmonary Percussive Ventilation for Children With Bronchiolitis on Non-Invasive Ventilation Support
Prospective randomized study of patients admitted to the Pediatric Intensive Care Unit suffering from Bronchiolitis and are supported on Non Invasive Positive Pressure Ventilation.
- Trial name
- NCT03037801
- Testing
- Intrapulmonary Percussive Ventilation (Percussionaire Corp, Sandpoint, Idaho)
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Soroka University Medical Center
Pediatric Lung Ultrasound, Pediatric Chest Radiography
Comparison of Lung Ultrasound and Chest Radiography for Pleural and Pulmonary Diagnosis in Pediatric Intensive Care Unit
In pediatric intensive care unit of Strasbourg, two exams are easily used for pleural and pulmonary diagnosis : chest radiography, which is the "historic" and reference exam, and commonly systematically the lung ultrasound.
- Conditions
- Pediatric Lung Ultrasound, Pediatric Chest Radiography, Pediatric Lung Diagnosis
- Trial name
- EchoRéaPed (NCT03939728)
- Testing
- Chest radiography and lung ultrasound
- Where
- France
- Volunteers
- 150 people
- Sponsor
- University Hospital, Strasbourg, France
Intensive Care Unit Patients
Effects of Exercise Intervention on Muscle Strength in Severely Ill Patients
In recent years, due to the improvement in the survival rate of the intensive care unit, the problem of severe systemic fatigue (Intensive care unit acquired weakness; ICUAW) has continued to receive attention.
- Trial name
- NCT05342129
- Testing
- exercise bike
- Where
- Taiwan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Taipei Veterans General Hospital, Taiwan
ICU, Trauma Injury
Current Situation and Analysis of ICU Management for Severe Trauma Patients in China
Over the past 10 years, there has not been a consensus on ICU nursing management based on the concept of injury control. Case management for patients with serious trauma continues to be initiated in general services and after…
- Conditions
- ICU, Trauma Injury, ICU Acquired Weakness
- Trial name
- NJJLISTP (NCT04944537)
- Testing
- No Intervention
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Lulu Gu
Continuous Renal Replacement Therapy (CRRT)
Comparison of Anticoagulant Effects of Different Doses of Nafamostat in Continuous Renal Replacement Therapy (CRRT) in the Intensive Care Unit (ICU)
This is a single-center, randomized, open-label, parallel-controlled clinical trial designed to investigate the anticoagulation efficacy and safety of different initial doses of Nafamostat Mesilate (NM) in ICU patients undergoing…
- Trial name
- NCT07469072
- Testing
- Nafamostat Low-Dose Group, Nafamostat High-Dose Group
- Where
- China
- Volunteers
- 92 people
- Sponsor
- Zhujiang Hospital
Acute Kidney Injury, Fluid Overload
Forced Fluid Removal in High Risk Acute Kidney Injury
The objective of this pilot trial is to assess the feasibility of forced fluid removal in patients admitted to the intensive care unit (ICU) with high-risk AKI and severe fluid overload.
- Conditions
- Acute Kidney Injury, Fluid Overload, Critical Illness
- Trial name
- FFAKI (NCT02458157)
- Testing
- Furosemide (Furix), Continuous renal replacement therapy (CRRT), Resuscitation
- Where
- 3 sites in Denmark
- Volunteers
- 21 people
- Sponsor
- Nordsjaellands Hospital
Medicines Reconciliation, Intensive Care Unit
Medicines Reconciliation at an Intensive Care Unit
This study evaluates the effect of performing medicines reconciliation on patients admitted to an intensive care unit. Half of the patients will receive a medicines reconciliation at the intensive care unit.
- Trial name
- NCT03173690
- Testing
- Medication reconciliation at the ICU, Medication Reconciliation at the Ward
- Where
- Norway
- Volunteers
- 50 people
- Sponsor
- University Hospital, Akershus
Pediatric Congenital Heart Surgery
Predictive Value of the FORE-SIGHT™ Monitor for Hemodynamic Deterioration
The postoperative period after congenital heart surgery in children can be a very critical episode, where it is of utmost importance to closely monitor the circulation in these patients.
- Trial name
- NCT01706497
- Testing
- Cerebral tissue oxygen saturation monitoring, blinded
- Where
- Belgium
- Volunteers
- 300 people
- Sponsor
- KU Leuven
Intensive Care (ICU), Age Over 80 Years
Pre-ICU Hospital Length of Stay and 30-day Mortality in the Very Old: a National Cohort of 315 042 ICU Admissions
How does waiting in hospital before intensive care affect older patients?Patients who become seriously ill are sometimes admitted to a regular hospital ward first, and only transferred to the intensive care unit (ICU) when their…
- Conditions
- Intensive Care (ICU), Age Over 80 Years, Hospital Length of Stay, Mortality
- Trial name
- NCT07571213
- Testing
- Time in hospital before ICU admission.
- Where
- Sweden
- Volunteers
- 315,042 people
- Sponsor
- Uppsala University
Respiratory Failure
Cuff Leak Test and Airway Obstruction in Mechanically Ventilated ICU Patients
The COSMIC trial will be a multicentred, national, parallel-group, pragmatic vanguard pilot trial.
- Trial name
- COSMIC (NCT05456542)
- Testing
- Cuff Leak Test, Dexamethasone 4mg
- Where
- 5 sites in United States, Canada and 1 more
- Volunteers
- 100 people
- Sponsor
- St. Joseph's Healthcare Hamilton
Sepsis, Septic Shock
Vitamin C, Hydrocortisone and Thiamine in Patients With Septic Shock
A great interest exists regarding substances with an immunomodulatory effect for sepsis patients. Recent data have shown that intravenous vitamin C, together with corticosteroids and thiamine, could prevent progressive organ…
- Trial name
- NCT05192213
- Testing
- Vitamin C
- Where
- 12 sites in Brazil
- Volunteers
- 71 people
- Sponsor
- Hospital Sirio-Libanes
Traumatic Brain Injuries, Brain Injuries,Traumatic
Doppler Ultrasonography Parameters and Mortality in Traumatic Brain Injury
The purpose of this study is to find out whether blood flow measurements of the brain and neck arteries, obtained with bedside Doppler ultrasonography are associated with neurological outcome and survival in adult patients with…
- Trial name
- NCT07890259
- Testing
- Transcranial and Carotid Doppler Ultrasonography
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people
- Sponsor
- Inonu University
Incontinence-associated Dermatitis
Prevention of Incontinence-associated Dermatitis and Maintenance of Local Skin Microclimate：A Multicenter Study
To explore the feasibility of Jefcare Sterile Medical Sheets in preventing incontinence-associated dermatitis and maintaining a stable local skin microclimate in adult patients in the intensive care unit.
- Trial name
- I-and-M-m (NCT06644027)
- Testing
- Jefcare Sterile Medical Sheets, Molicare Premium Bed Mat
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Sir Run Run Shaw Hospital
Acute Aluminum Phosphide Poisoned Cases
Role of Combination Therapy of Glucose Insulin Potassium Infusion (GIK), Intravenous Hydrocortisone and Oral Sevelamer in Treatment of Acute Aluminum Phosphide Poisoned Cases Admitted to Intensive Care Unit (ICU) at Sohag University Hospitals.
Metal phosphides are commonly utilized for safeguarding stored grains due to their desirable characteristics. They have high potency and the ability to combat different pests and produce non-toxic residues in crops .
- Trial name
- NCT07451561
- Testing
- Gastric lavage with paraffin oil, GIK solution
- Where
- Egypt
- Volunteers
- 74 people
- Sponsor
- Sohag University
Critical Illness, Pneumonia, Viral
Comparison Between Different Doses of Steroids in COVID-19 Patients
aim of this study is to compare between standard dose methyl prednisolone and mega dose methyl prednisolone as regards outcome reflected by mortality rate, percentage of mechanically ventilated patients and icu length of stay of…
- Trial name
- COVID-19 (NCT05279482)
- Testing
- observation for outcome of methylprednisolone dose
- Where
- 2 sites in Egypt
- Volunteers
- 104 people
- Sponsor
- Ain Shams University
Infection in ICU, Sepsis
Early Optimization of Ceftazidime Regimen in Critical Care
Hospital-acquired infections, most of which are caused by Gram-negative bacteria, are common in intensive care units and have a major impact on patient prognosis.
- Conditions
- Infection in ICU, Sepsis, Septic Shock, Pseudomonas Aeruginosa Infection
- Trial name
- FORTOPTIM_1 (NCT07085624)
- Testing
- ceftazidime, plasma ceftazidime dosage
- Where
- 8 sites in France
- Volunteers
- 128 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Intubation Complication
Apneic Oxygenation in the Pediatric Intensive Care Unit
The purpose of the study is to determine the impact of apneic oxygenation on the time to desaturation in pediatric patients treated in a pediatric intensive care unit (PICU).
- Trial name
- NCT03374046
- Testing
- Apneic Oxygenation
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Wake Forest University Health Sciences