Clinical trials: ICU
Infant, Premature Development
The Impact of Implementing NIDCAP on the Developmental Sensitivity of Nurses Caring for Preterm Infants
The purpose of this study is to determine whether implementing the Newborn Individualized Developmental Care and Assessment Program increases NICU nurses' sensitivity in meeting the developmental care needs of preterm infants.
- Trial name
- NCT00179985
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
Intensive Care Unit
Removal of mtDNA in Plasma by Continous Venovenous Hemofiltration in Sepsis
The plasma level of mtDNA in sepsis is affected by continous venovenous hemofiltation（CVVH）
- Trial name
- NCT04083482
- Testing
- continous venovenous hemofiltraion
- Where
- China
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- First People's Hospital of Chenzhou
Newborn Basic Care Training
THE EFFECT OF BRAHMS' LULLABY DURING SPONGE BATH ON NEONATAL COMFORT AND PHYSIOLOGICAL PARAMETERS
This study aims to examine the effect of playing Brahms' lullaby during sponge bathing on neonatal comfort and physiological parameters in a neonatal intensive care unit.
- Trial name
- NCT07468682
- Testing
- Brahms' Lullaby, Routine Sponge Bath
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people
- Sponsor
- Gamze Gocmen
COVID-19 Acute Respiratory Distress Syndrome
Rehabilitation of Critically Ill Patients With SARS-CoV-2 Variants in ICU With Limited Resources
Acute rehabilitation in critically ill patients can improve post-intensive care unit (post-ICU) physical function. Scientific evidence has considered neuromuscular electrical stimulation (NMES) as a promising approach for the…
- Trial name
- NCT05450120
- Testing
- Functional Rehabilitation, Neuromuscular Electrical Stimulation
- Where
- Brazil
- Volunteers
- 88 people
- Sponsor
- Universidade Federal de Sao Carlos
Critical Illness, Respiratory Failure
Treatment of Muscle Weakness in Critically Ill Patients
Patients who are admitted to the intensive care unit and require mechanical ventilation frequently develop profound respiratory and limb muscle weakness.
- Conditions
- Critical Illness, Respiratory Failure, Myopathy, Weakness
- Trial name
- NCT02247895
- Testing
- Electrical stimulation
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Gerald Supinski
Sleep Quality, Pain
Comparing the Efficacy of Earplugs and Eye Masks on Pain and Sleep Quality
Objective: To determine the superiority of earplugs and eye masks to each other and their efficacy in pain and sleep quality. Methods: The study was a three-arm randomised controlled trial.
- Conditions
- Sleep Quality, Pain, Intensive Care Medicine, Cardiac Surgery
- Trial name
- NCT07100002
- Testing
- Control Group, Earplug Group, Eye mask Group
- Where
- Turkey (Türkiye)
- Volunteers
- 75 people
- Sponsor
- Giresun University
Ventilator Associated Pneumonia
Ventilator Associated Pneumonia Multiplex PCR for Anti-Infective Regimens
Ventilator-associated pneumonia (VAP) remains one of the main nosocomial infections acquired in the intensive care unit (ICU). VAP is pneumonia occurring 48 hours after intubation.
- Trial name
- VAMPAIR (NCT06554327)
- Testing
- Multiplex PCR
- Where
- France
- Volunteers
- 265 people
- Sponsor
- CHU de Reims
Rare Diseases
NICUSeq: A Trial to Evaluate the Clinical Utility of Human Whole Genome Sequencing (WGS) Compared to Standard of Care in Acute Care Neonates and Infants
Prospective, multi-site, study to evaluate the clinical utility of cWGS in a proband. One group will receive cWGS and a clinical report approximately 15 days after blood samples are received, while the other group will continue…
- Trial name
- NICU-Seq (NCT03290469)
- Testing
- clinical whole genome sequencing (cWGS)
- Where
- 5 sites in United States
- Volunteers
- 355 people
- Sponsor
- Illumina, Inc.
Intensive Care Unit, Arterial Catheter
Ankle Measurements of Arterial Pressure: Semi-recumbent or Horizontal Position.
The upper arm is sometimes inaccessible for arterial pressure (AP) measurement. Placing the automatic cuff at the ankle is a common alternative. However, whether AP measurement at the ankle is reliable is uncertain.
- Trial name
- 2PAC (NCT06032169)
- Testing
- Patients of a surgical intensive care unit having an arterial catheter
- Where
- France
- Volunteers
- 51 people
- Sponsor
- Nantes University Hospital
Delirium
Nursing Intervention to Reduce Incidence and Duration of Delirium in Patients in Intensive Care
Introduction: Delirium is a cognitive alteration of acute onset and fluctuating course, characterized by the reduced capacity to pay attention to the environment, memory impairment, disorientation, language, and perception…
- Trial name
- NCT05172583
- Testing
- Control, Interventions to reduce delirium based on DSM and scientific evidence
- Where
- Colombia
- Volunteers
- 213 people, healthy volunteers welcome
- Sponsor
- Universidad Surcolombiana
Educational Modules Given to French Juniors Taking the Postgraduate Critical Care Diploma
Identification of Take Home Message in Lecture Based Learning
Medical education involves the acquisition of a large quantity of information. Lecture-based learning (LBL) is the best known of conventional teaching methods.
- Trial name
- T-REX 2 (NCT01795651)
- Testing
- identification of take-home message of lecture
- Where
- France
- Volunteers
- 77 people
- Sponsor
- University Hospital, Clermont-Ferrand
Acute Respiratory Failure (ARF), Hypertension
EIT Evaluation of Different Antihypertensive Agents on the Ventilation-Perfusion Ratio in Patients With Acute Respiratory Failure
This prospective, single-center interventional study aims to evaluate the effect of two commonly used intravenous antihypertensive agents - nicardipine and nitroglycerin - on lung ventilation-perfusion (V/Q) distribution in…
- Conditions
- Acute Respiratory Failure (ARF), Hypertension, Pulmonary Perfusion Imbalance, Aortic Dissection (Subset)
- Trial name
- NCT07603037
- Testing
- Nitroglycerin, Nicardipine
- Where
- China
- Volunteers
- 12 people
- Sponsor
- First Affiliated Hospital of Wannan Medical College
Intensive Care Unit, Cardiac Surgery
The Effect of Light Therapy on Post-Surgical Pain
Researchers aim to demonstrate that the use of phototherapy is feasible and may reduce acute postoperative pain based on recent literature.
- Trial name
- NCT05853731
- Testing
- Green light emitting diode, White light emitting diode
- Where
- United States
- Sponsor
- Mayo Clinic
Delirium, Aging
MIND-ICU Study: Delirium and Dementia in Veterans Surviving ICU Care
This will be the first large cohort study to define the epidemiology of and identify modifiable risk factors for long-term CI and functional deficits of ICU survivors.
- Conditions
- Delirium, Aging, Dementia
- Trial name
- NCT00400062
- Where
- 3 sites in United States
- Volunteers
- 800 people
- Sponsor
- VA Office of Research and Development
Ventilator-Associated Pneumonia
Mobile-Based Microlearning for Improving ICU Nurses' Adherence to Ventilator-Associated Pneumonia Prevention Protocols
Ventilator-associated pneumonia (VAP) is one of the most common healthcare-associated infections among mechanically ventilated patients and is associated with increased morbidity, mortality, length of intensive care unit stay…
- Trial name
- VAP-ML (NCT07866027)
- Testing
- Mobile-Based Microlearning Program, Routine Education
- Where
- Egypt
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Alexandria University
Systemic Lupus Erthematosus, Childhood-onset Systemic Lupus Erythematous
Gyrotonic Exercise in Lupus Adolescents Who Survived From Intensive Care
lupus adoelscented who recently survive from intenive care unit usually complain postintenive care unit syndrome in addition to stress, fatigue, low life quality, depression, low physical performance, low grip strenght, insomnia…
- Conditions
- Systemic Lupus Erthematosus, Childhood-onset Systemic Lupus Erythematous, Intensive Care Unit Survivors, Adolescents
- Trial name
- NCT07833020
- Testing
- Gryotonic exercise
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Acute Respiratory Failure, Heart Failure
Tracheostomy in ICU With a Double Lumen Endotracheal Tube
Percutaneous tracheostomy in Intensive care unit (ICU) is performed with the use of flexible fiberoptic bronchoscope inside the conventional single lumen endotracheal tube owned by the patients.
- Conditions
- Acute Respiratory Failure, Heart Failure, Neurological Disease
- Trial name
- NCT01691222
- Testing
- Double lumen endotracheal tube tracheostomy
- Where
- 2 sites in Italy
- Volunteers
- 30 people
- Sponsor
- University of Genova
Delirium
Delirium Detection in Pediatric Intensive Care Unit Through a French Translation of the CAPD : a French Monocentric Observational Study
The purpose of this study is to introduce delirium detection and try to determine the prevalence of delirium in Pediatric Intensive Care Unit (PICU) using a validated tool : the Cornell Assessment of Pediatric Delirium (CAPD) for…
- Trial name
- DeliReP (NCT04954261)
- Testing
- CAPD
- Where
- France
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Respiratory Failure
Cuff Leak Test and Airway Obstruction in Mechanically Ventilated ICU Patients
The COSMIC trial will be a multicentred, national, parallel-group, pragmatic vanguard pilot trial.
- Trial name
- COSMIC (NCT05456542)
- Testing
- Cuff Leak Test, Dexamethasone 4mg
- Where
- 5 sites in United States, Canada and 1 more
- Volunteers
- 100 people
- Sponsor
- St. Joseph's Healthcare Hamilton
Dysphagia, Dysphagia, Swallowing Function, Diet Modification, Dysphagia Diet, Diet Standardization
GUSS-ICU Safe Nutrition Program After Extubation in ICU Patients
The aim of this study is to evaluate the effects of using the GUSS-ICU Safe Nutrition Program after extubation in Intensive Care Unit patients.
- Trial name
- NCT07195383
- Testing
- Nutrion plan based on GUSS-ICU scale
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 82 people
- Sponsor
- Istanbul University - Cerrahpasa