Clinical trials: IBS
Irritable Bowel Syndrome
IBS Personalized Diet vs. Low FODMAP Diet Randomized Control Trial
Irritable bowel syndrome (IBS) is considered the most common gastrointestinal disorder in humans, with an estimated global prevalence of 11%-20% of all humans.
- Trial name
- NCT05972317
- Testing
- Standard Low FODMAP dietary regimen, personalized low FODMAP dietary regimen
- Where
- Israel
- Volunteers
- 30 people
- Sponsor
- Weizmann Institute of Science
Irritable Bowel Syndrome (IBS)
Abdominal Symptom Phenotype Study in Children
Children and adults commonly suffer from recurrent abdominal (stomach) pain. One type is called irritable bowel syndrome (IBS). IBS in adults and children is one of the most common and costly health care problems in the US.
- Trial name
- ASPPNB (NCT01204515)
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Irritable Bowel Syndrome (IBS)
Evaluate the Effect of Synbiotics in Irritable Bowel Syndrome
Irritable Bowel Syndrome (IBS) is a brain-gut-disorder characterized by a chronic relapsing-remitting nature of symptoms, including abdominal pain and altered bowel habits.
- Trial name
- IBSXtra02 (NCT06647043)
- Testing
- SMT04 Pro
- Where
- Malaysia
- Volunteers
- 20 people
- Sponsor
- Universiti Sains Malaysia
Irritable Bowel Syndrome (IBS)
Exercise and Vagus Nerve Stimulation in IBS
The aim of the study was to consider the possible role of exercise and vagus nerve on bowel functionality in chronic IBS and to demonstrate that exercise and transcutaneous auricular stimulation of the vagus nerve can reduce…
- Trial name
- NCT06769516
- Testing
- Auricular Vagus Nerve Stimulation (aVNS), Aerobic Exercise Therapy, Low FODMAP Diet Intervention
- Where
- United Kingdom
- Volunteers
- 90 people
- Sponsor
- Bahçeşehir University
Irritable Bowel Syndrome (IBS)
Irritable Bowel Syndrome Survey in Gastroenterological Adult Outpatients in China
The primary objective of this study is to estimate the overall prevalence of IBS medically diagnosed and diagnosed using Rome III or IV criteria in GI adult outpatients in China.
- Trial name
- IRONS (NCT02955316)
- Where
- China
- Volunteers
- 3,000 people
- Sponsor
- AstraZeneca
Irritable Bowel Syndrome
Association Between High Faecal Calprotectin, Increased Intestinal Permeability and Visceral Hypersensitivity in IBS-D Patients
Visceral hypersensitivity, low grade inflammation and increased intestinal permeability are three main pathophysiological mechanisms involved in irritable bowel syndrome. The connexion between these abnormalities is not known.
- Trial name
- SIIMPA (NCT02550704)
- Testing
- Colonoscopy with eleven biopsies in the left colon to assess intestinal permeability
- Where
- France
- Volunteers
- 34 people
- Sponsor
- University Hospital, Rouen
Irritable Bowel Syndrome
A 14-week Pilot Prospective Clinical Trial With BiOkuris Product in Patients With Irritable Bowel Syndrome
Irritable Bowel Syndrome (IBS) is a common chronic gastrointestinal condition that affects approximately 10-20% of adults in Western countries.
- Trial name
- NCT05780749
- Testing
- DDI-IBS-001
- Where
- 11 sites in Belgium
- Volunteers
- 116 people
- Sponsor
- Biokuris s.a.
Abdominal Pain/ Discomfort, Irritable Bowel Syndrome
The Mechanism Underlying the Analgesic Effect of the Music of IBS Pain
The proposed pilot study aims to assess the underlying mechanisms of the MBI on IBS pain and the feasibility of using novel technology in the outcome measurements.
- Trial name
- NCT06706778
- Testing
- Music intervention
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Yale University
IBS (Irritable Bowel Syndrome)
A Prospective Trial of a Variable Compression System for Moderate to Severe Irritable Bowel Syndrome
This prospective, interventional trial is intended to determine the safety and effectiveness of the Variable Compression System (VCS) device for Irritable Bowel Syndrome (IBS).
- Trial name
- NCT07540312
- Testing
- Variable Compression System
- Where
- 3 sites in United States
- Volunteers
- 20 people
- Sponsor
- PGP Health
Irritable Bowel Syndrome, Diarrhea
Does Welchol (Colesevelam Hydrochloride) Improve Colonic Transit in Diarrhea-predominant Irritable Bowel Syndrome (D-IBS)?
Our hypothesis is that the medication approved for treatment of high blood cholesterol levels, Colesevelam HCl (WELCHOL), decreases colonic transit and permeability in patients with diarrhea due to irritable bowel syndrome.
- Trial name
- welchol (NCT00911612)
- Testing
- Colesevelam
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Mayo Clinic
Ulcerative Colitis, Crohn Disease
Systems Biology of Gastrointestinal and Related Diseases
This is a longitudinal observational study on patients with gastrointestinal and related disease. The study will be conducted for at least 10 years, following each participant over time, as they either go through relapses and…
- Conditions
- Ulcerative Colitis, Crohn Disease, Obesity, Colon Polyp
- Trial name
- NCT05579444
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Viome
Irritable Bowel Syndrome, Relief of Irritable Bowel Syndrome Symptoms
Effects of Cultura Yoghurt in Irritable Bowel Syndrome (IBS) Patients on Intestinal and Immunological Changes
To determine the effect of cultura probiotic yoghurt on number of responders to treatment during 8 weeks of treatment in comparison to placebo.
- Conditions
- Irritable Bowel Syndrome, Relief of Irritable Bowel Syndrome Symptoms, Quality of Life
- Trial name
- NCT01127828
- Testing
- Arla Yoghurt with no probiotic, Probiotic yoghurt (Cultura)
- Where
- Sweden
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Good Food Practice, Sweden
Irritable Bowel Syndrome
Effectiveness of Internet Delivered Cognitive Behavior Therapy (CBT) for Irritable Bowel Syndrome (IBS)
The study will recruit 80 out-patients diagnosed with Irritable Bowel Syndrome from a gastroenterological clinic. The recruitment will be consecutive with all patients receiving the diagnosis being offered to participate.
- Trial name
- NCT00844961
- Testing
- Internet delivered cognitive behavior therapy
- Where
- Sweden
- Volunteers
- 61 people
- Sponsor
- Karolinska Institutet
Irritable Bowel Syndrome
Saliva Testosterone Increases in Irritable Bowel Syndrome (IBS) Patients Beginning Choir Singing
The hypothesis was that a one-year experience of choir singing once a week is more beneficial than group discussions to saliva concentration of testosterone.
- Trial name
- NCT00931294
- Testing
- Choir singing, Information Group
- Where
- Sweden
- Volunteers
- 55 people
- Sponsor
- Stockholm University
Irritable Bowel Syndrome, Obesity
Moderate Continuous Versus High Interval Intensity Training on Gut Dysbiosis and GLP1 Hormone in IBS
investigating the response of gut bacteria via measuring short chain fatty acids and Glucagon like peptide hormone to two different modes of exercises in pre-diabetic, obese patients with irritable bowel syndrome.
- Conditions
- Irritable Bowel Syndrome, Obesity, Dysbiosis
- Trial name
- NCT06408610
- Testing
- moderate intensity continuous training
- Where
- 2 sites in Egypt
- Volunteers
- 66 people
- Sponsor
- Cairo University
Irritable Bowel Syndrome
Effectiveness of On-demand Meteospasmyl® Use in Irritable Bowel Syndrome (IBS)
The purpose of this study is to compare the effectiveness of 2 IBS treatment strategies: Strategy A = MeteoSpasmyl®, on-demand therapy Strategy B = standard of care chosen by the physician
- Trial name
- NCT01404923
- Testing
- anti spasmodic agents, alverine citrate, simeticone
- Volunteers
- 436 people
- Sponsor
- Laboratoires Mayoly Spindler
Food Intolerance Syndromes, Small Intestinal Bacterial Overgrowth Syndrome (SIBO)
Combined Lactulose H2-breath Test With Abdominal Imaging
Hydrogen (H₂) breath tests serve several purposes. (i) detect malabsorption of carbohydrates such as lactose and fructose, (ii) measurement of oro-caecal transit time (iii) associate hydrogen production with the onset of…
- Conditions
- Food Intolerance Syndromes, Small Intestinal Bacterial Overgrowth Syndrome (SIBO), Breath Tests
- Trial name
- NCT07145580
- Where
- Switzerland
- Volunteers
- 510 people
- Sponsor
- Klinik Arlesheim
Abdominal Pain, Irritable Bowel Syndrome
Recurrent Abdominal Pain in Children
The purpose of this study is to: 1. To determine if fiber versus placebo improves symptoms in children with recurrent abdominal pain/irritable bowel syndrome. 2.
- Trial name
- NCT00526903
- Testing
- Elimination Diet
- Where
- United States
- Volunteers
- 168 people
- Sponsor
- Baylor College of Medicine
Inflammation, Colon, Irritable
The Role of Intestinal Inflammation in Irritable Bowel Syndrome (IBS)
The research project addresses the following hypotheses (A) the normal balance of beneficial and detrimental commensal intestinal bacteria is deranged in IBS, with selective alterations in clinically defined patient subsets i.e.…
- Conditions
- Inflammation, Colon, Irritable, Colonic Diseases, Functional, Irritable Bowel Syndrome
- Trial name
- K23 (NCT01072903)
- Where
- United States
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Irritable Bowel Syndrome
Evaluation of the Efficacy of Two Probiotic Strains for Irritable Bowel Syndrome
The purpose of this study is to determine if two different probiotic strains, Lactobacillus paracasei HA-196 and Bifidobacterium longum R0175, are effective in helping subjects manage the symptoms of IBS
- Trial name
- 14PIHL (NCT02213172)
- Testing
- Bifidobacterium longum R0175, Lactobacillus paracasei HA-196
- Where
- Canada
- Volunteers
- 285 people
- Sponsor
- KGK Science Inc.