Clinical trials: IBD
Inflammatory Bowel Disease, Rheumatoid Arthritis
A Trial to Determine the Effects of Exercise in Inflammatory Bowel Disease and Rheumatoid Arthritis
The purpose of this study is too determine the effects of exercise on the gut microbiota and immunological markers in patients with inflammatory bowel disease and rheumatoid arthritis.
- Trial name
- ExMET-IBD (NCT02463916)
- Testing
- Exercise
- Where
- Ireland
- Volunteers
- 60 people
- Sponsor
- University College Cork
Inflammatory Bowel Diseases
Survey Study About Endoscopy During COVID-19 Pandemic for IBD Doctors
Performance of diagnostic or therapeutic endoscopic procedures in inflammatory bowel disease (IBD) patients can be challenging during a viral pandemic; the main concerns being the safety and protection of patients and health care…
- Trial name
- NCT04970849
- Testing
- observation
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
IBS - Irritable Bowel Syndrome
Innovative Tools to Produce Legume-based Foods for Increased Consumer Acceptance
The aim of this study is to investigate the effects of enzymatic treatment to reduce GOS (galactooligosaccharides) in legume-based crackers in IBS (irritable bowel syndrome) persons.
- Trial name
- LeguComf (NCT05118243)
- Testing
- Control cracker, Enzyme-treated cracker
- Where
- Finland
- Volunteers
- 20 people
- Sponsor
- University of Helsinki
Irritable Bowel Syndrome
Serum Levels of Apelin, Chemerin and Adiponectin Adipokines in Irritable Bowel Syndrome and Healthy Subjects
In this observational case-control study investigators aimed to assess the serum levels of adipokines such as Apelin, Chemerin and adiponectin in patients with irritable bowel syndrome (IBS), and compare it with healthy controls.
- Trial name
- NCT03366389
- Where
- Iran
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Amir Abbasnezhad
Crohn's Disease (CD), Ulcerative Colitis (UC)
Virtual Group Therapy for IBD Patients With Anxiety and Depression
This study is being done to better understand the complex relationship between mental health and Inflammatory Bowel Disease (IBD), with a particular focus on symptoms of depression and anxiety.
- Conditions
- Crohn's Disease (CD), Ulcerative Colitis (UC), Inflammatory Bowel Diseases (IBD), Anxiety
- Trial name
- NCT07796568
- Testing
- Group Psychotherapy Intervention
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- University of Chicago
Crohn's Disease
Optimizing Cimzia in Crohn's Patients
The purpose of this study is to determine if increasing the dose and/or dosing frequency of certolizumab pegol (Cimzia) is effective in regaining and optimizing response in patients with moderate to severe Crohn's disease.
- Trial name
- NCT01024647
- Testing
- certolizumab pegol
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Atlanta Gastroenterology Associates
Rheumatoid Arthritis, Ankylosing Spondylitis
Assessment of Rheumatoid Arthritis, Psoriatic Arthritis, Ankylosing Spondylitis, Plaque Psoriasis, Crohn's Disease and Ulcerative Colitis Patients´ Adherence Attitudes to Maintenance Therapy With a Scheduled Adalimumab Treatment in Routine Clinical Practice
The purpose of this non-interventional, multicenter, post-marketing observational study (PMOS) was to assess rheumatoid arthritis (RA), psoriatic arthritis (PsA), ankylosing spondylitis (AS), plaque psoriasis (PS), Crohn's…
- Conditions
- Rheumatoid Arthritis, Ankylosing Spondylitis, Psoriatic Arthritis, Crohn´s Disease
- Trial name
- Adherence (NCT01768858)
- Testing
- Adalimumab
- Volunteers
- 96 people
- Sponsor
- AbbVie
Diarrhea Predominant Irritable Bowel Syndrome
Effect of Ranolazine on Gastrointestinal Motor Function and Pain in Patients With IBS-D
Will Ranolazine improve bowel function and abdominal pain in human subjects with IBS-D?
- Trial name
- Ranolazine (NCT02239926)
- Testing
- Ranolazine
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Mayo Clinic
Inflammatory Bowel Diseases
Mindfulness-based Cognitive Therapy for Patients With Inflammatory Bowel Disease
Considering the limited availability of psychosocial interventions for IBD, this study aims to investigate MBCT as an adjunctive treatment to treatment as usual to reduce psychological stress and improve sleep quality/regularity…
- Trial name
- NCT04646785
- Testing
- Mindfulness-based cognitive therapy + TAU, Treatment as usual (TAU)
- Where
- 4 sites in Netherlands
- Volunteers
- 142 people
- Sponsor
- Radboud University Medical Center
Inflammatory Bowel Diseases, Crohn's Disease
Efficacy and Safety Study of Tripterygium Glycoside in the Treatment of Crohn's Disease for Induction Remission
The purpose of this study is to assess the effect and safety of Tripterygium Glycosides in the treatment of Crohn's disease for induction remission and compare the therapeutic effect with patients who received mesalazine.
- Conditions
- Inflammatory Bowel Diseases, Crohn's Disease, Gastrointestinal Diseases, Digestive System Diseases
- Trial name
- NCT02044952
- Testing
- Mesalazine, Tripterygium glycosides
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Zhu Weiming
Crohn's Enteritis, Crohn Disease
Physical Fitness Levels in Children and Adolescents With Chronic Inflammatory Bowel Disease (CIBD): Crohn's Disease, Ulcerative Colitis, Chronic Unclassified Colitis
Inflammatory bowel diseases (IBDs), including Crohn's disease (CD), ulcerative colitis (UC) and IBD-unclassified (IBD-U), are characterised by chronic inflammation of the gastrointestinal tract.
- Conditions
- Crohn's Enteritis, Crohn Disease, Inflammatory Bowel Diseases, Colitis, Ulcerative
- Trial name
- MICI-FIT (NCT04647578)
- Testing
- GT3X Actigraph accelerometer.
- Where
- France
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Hospital, Lille
Irritable Bowel Syndrome
The Impact of Dietary Treatment in Patients With Irritable Bowel Syndrome
The obtained results are likely to determine whether changes in the diet of patients with irritable bowel syndrome will affect their nutritional status.
- Trial name
- NCT04307368
- Testing
- FODMAP diet, Elimination-rotational diet, Classic diet
- Volunteers
- 73 people
- Sponsor
- Medical University of Bialystok
Irritable Bowel Syndrome
Efficacy of a Low FODMAP Diet in the Absence of Lactose Malabsorption in Moderate to Severe ROME IV IBS.
Irritable bowel syndrome (IBS) is a frequently encountered disorder. According to the Rome IV criteria, it is characterized by abdominal pain associated with a change in stool frequency or con-sistency, or with symptomatic…
- Trial name
- NCT05120752
- Testing
- FODMAP diet
- Where
- Belgium
- Volunteers
- 60 people
- Sponsor
- Universitair Ziekenhuis Brussel
LRG Levels
Effectiveness of Serum Leucine-rich Alpha-2 Glycoprotein Levels on IBD
We attempt to examine the association between serum leucine-rich alpha-2 glycoprotein (LRG) levels and endoscopic activity in patients with possible ulcerative colitis (UC) or Crohn's disease (CD) to determine whether LRG was a…
- Trial name
- NCT04535882
- Testing
- serum leucine-rich alpha-2 glycoprotein (LRG) levels
- Where
- Japan
- Volunteers
- 673 people
- Sponsor
- Showa Inan General Hospital
Inflammatory Bowel Diseases, Ulcerative Colitis
Personalized B-fructan Diet in Inflammatory Bowel Disease Patients
This study aims to examine patient tolerability of personalized dietary fibre consumption recommendations (high-pectin diet versus high-B-fructan diet based on personalized responses), provided by an IBD dietician, based on our…
- Trial name
- NCT05615779
- Testing
- Randomized B-fructan diet, Personalized pectin diet, Personalized B-fructan diet
- Where
- 2 sites in Canada
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Ileostomy - Stoma, Colorectal Surgery
Readmission and Dehydration Prevention in Patients With Elective Ileostomy
The goal of this prospective observational study is to evaluate the adherence to DRIP score calculation and the application rate of each proposed item to prevent dehydration and readmission in patients undergoing ileostomy…
- Conditions
- Ileostomy - Stoma, Colorectal Surgery, Dehydration
- Trial name
- PREDESTO (NCT06824623)
- Where
- 7 sites in Italy
- Volunteers
- 300 people
- Sponsor
- Multidisciplinary Italian Study group for STOmas (MISSTO)
Inflammatory Bowel Disease, Crohn Disease
Improving OutcoMes in the Pediatric to Adult Care Transition in Inflammatory Bowel Disease
The transition from pediatric to adult IBD care can be stressful and wrought with challenges including access to care and establishment of new physician-patient relationships.
- Conditions
- Inflammatory Bowel Disease, Crohn Disease, Colitis, Ulcerative
- Trial name
- IMPACT-IBD (NCT02085083)
- Testing
- Telephone and email correspondence with an Inflammatory Bowel Disease Nurse, Minimal Intervention Arm
- Where
- 3 sites in Canada
- Volunteers
- 150 people
- Sponsor
- Mount Sinai Hospital, Canada
Ulcerative Colitis
The Effectiveness of Well-being Therapy on Mental Health and Self-efficacy of Patients With Ulcerative Colitis
Ulcerative colitis (UC) is a chronic and lifelong disease that causes disabilities for sufferers and causes mental health disorders in the patients.
- Trial name
- NCT05645666
- Testing
- Well-being therapy
- Where
- Iran
- Volunteers
- 32 people
- Sponsor
- Islamic Azad University, Isfahan (Khorasgan) Branch
Irritable Bowel Syndrome
Aerobic Exercise Verus Acupuncture on the Quality of Life in Women Suffering From Irritable Bowel Syndrome
To compare the effect of aerobic exercise and the acupuncture on the quality of life in women with irritable bowel syndrome
- Trial name
- NCT05947929
- Testing
- Aerobic excise, acupuncture
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Crohn Disease
A Study Testing How BI 655130 Works in Patients With Fistulizing Crohn's Disease
This is a study in adults with Crohn's Disease who also have fistulas near the anus. The study has 2 parts. The first part is to find out more about what causes the fistulas.
- Trial name
- NCT03752970
- Testing
- Spesolimab
- Where
- 10 sites in Austria, Belgium and 6 more
- Volunteers
- 27 people
- Sponsor
- Boehringer Ingelheim