Clinical trials: Hypoxemia
Intraoperative Hypertension, Pain Threshold
Post SARS-Cov-2 Disease Anesthesia Events
Estimating and recording the rate of occurrence of pulmonary and cardiovascular complications during the perioperative period in patients with past covid infection
- Conditions
- Intraoperative Hypertension, Pain Threshold, Postoperative Pain, Postoperative Hypoxemia
- Trial name
- NCT05252234
- Testing
- Observation of hemodynamic status and post operative pain
- Where
- Egypt
- Volunteers
- 180 people
- Sponsor
- Ain Shams University
Sleep Disorders
Screening for Sleep Hypoxemia in Pulmonary Arterial Hypertension
In the investigators study, and regarding results of small cohorts in the literature, the investigators hypothesize that hypoxemia is frequent in IPAH and CPEPH.
- Trial name
- Sommeil_HTAP (NCT01371669)
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Hypoxemia
Effects of a Face Mask on Oxygenation During Exercise
There is concern that wearing a face mask during COVID will affect oxygen uptake, especially during intense exercise. This study will assess the effect of wearing two different face masks (disposable and cloth) on blood and…
- Trial name
- NCT04557605
- Testing
- Progressive cycling exercise test to exhaustion
- Where
- Canada
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
Hypoxemia
Oxygen Saturation Alarms in the Neonatal Intensive Care Unit
Infants will be observed in the neonatal intensive care unit for 4 hours. The observer will note the timing of oxygen saturation alarms, staff response, and interrupted staff activities.
- Trial name
- NCT01085539
- Where
- 3 sites in United States
- Volunteers
- 50 people
- Sponsor
- Medtronic - MITG
Hypoxemia
Therapy With High-flow Oxygen by Nasal Cannula vs Noninvasive Ventilation in Patients With Acute Hypoxemic Respiratory Failure: a Crossover Physiologic Study
Background and rationale: A large multicenter randomized controlled trial demonstrated that in patients with hypoxemic non-hypercapnic respiratory failure treatment with nasal high flow oxygen (NHF) resulted in a reduction of the…
- Trial name
- THIFON (NCT03865056)
- Testing
- Optiflow (High-flow Nasal Cannula), Non-invasive Ventilation
- Volunteers
- 20 people
- Sponsor
- University Health Network, Toronto
Idiopathic Pulmonary Fibrosis, Hypoxemia
Effects of Oxymizer Pendant Cannula Versus Conventional Nasal Cannula During Endurance Shuttle Walk Tests in Hypoxemic Patients With Idiopathic Pulmonary Fibrosis
Aim of this study is to investigate the effects of an Oxymizer pendant nasal cannula in hypoxemic patients with idiopathic pulmonary fibrosis during walking.
- Trial name
- IPF/Oxymizer2 (NCT03411876)
- Testing
- Oxymizer® pendant nasal cannula, conventional nasal cannula
- Where
- Germany
- Volunteers
- 22 people
- Sponsor
- Klaus Kenn
Adverse Respiratory Events, Hypoxemia
Comparing Esketamine and Remazolam With Propofol for Breathing Safety in Pediatric Gastroscopy
Gastroscopy is important for diagnosing and treating upper gastrointestinal diseases in children. To ensure the procedure is safe and smooth, most children require sedation.
- Conditions
- Adverse Respiratory Events, Hypoxemia, Children, Gastroscopy
- Trial name
- NCT07748884
- Testing
- Fentanyl and Propofol, Esketamine and remimazolam
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Second Affiliated Hospital of Wenzhou Medical University
Benign Prostate Hypertrophy(BPH), Obstructive Sleep Apnea( OSA)
Nocturnal Hypoxemia and Benign Prostatic Hyperplasia in OSA Patients
Obstructive Sleep apnea (OSA) is a common sleep disorder characterized by frequent partial or complete obstructions of the upper airway during sleep leading to sleep fragmentation and sympathetic activation.
- Trial name
- NCT07058038
- Where
- Egypt
- Volunteers
- 91 people
- Sponsor
- Mansoura University
Pneumonia, Hypoxaemia
Use of Bubble Continuous Positive Airway Pressure Compared to Nasal Prong Oxygen or Humidified High Flow in Children Under Five With Severe Pneumonia and Hypoxaemia
Continuous Positive Airway Pressure (CPAP) is a common form of support for patients admitted to Intensive Care Units (ICUs) of industrialized countries with respiratory distress (1).
- Trial name
- NCT01396759
- Testing
- Bubble continuous positive airway pressure, Humidified high flow air / O2 mix at 2 l/kg/min, Standard O2 supplementation by nasal cannula at 0.5 - 2 l/min
- Where
- Bangladesh
- Volunteers
- 975 people
- Sponsor
- International Centre for Diarrhoeal Disease Research, Bangladesh
High Flow Nasal Cannula, Oxygen Therapy
Closed-loop Oxygen Control for High Flow Nasal Therapy
In patients with acute hypoxemic respiratory failure (AHRF), High Flow Nasal Therapy (HFNT) improves oxygenation, tolerance, and decrease work of breathing as compared to standard oxygen therapy by facemask.
- Conditions
- High Flow Nasal Cannula, Oxygen Therapy, Hypoxemia, Hyperoxemia
- Trial name
- HILOOP (NCT04965844)
- Testing
- Oxygen close-loop, No intervention
- Where
- Spain
- Volunteers
- 53 people
- Sponsor
- Hospital Universitari Vall d'Hebron Research Institute
Intubation Complication, Intubation; Difficult or Failed
Nasotracheal Intubation With VL vs DL in Infants Trial
Nasotracheal Intubation with Videolaryngoscopy versus Direct Laryngoscopy in Infants (NasoVISI) Trial is a prospective randomized multicenter study. The study will be conducted at 8 centers in the United States.
- Conditions
- Intubation Complication, Intubation; Difficult or Failed, Hypoxia, Hypoxemia
- Trial name
- NasoVISI (NCT05433155)
- Testing
- Nasotracheal intubation
- Where
- 8 sites in United States
- Volunteers
- 680 people
- Sponsor
- Children's Hospital of Philadelphia
Oxygen Deficiency, Apnea
Oxygen Reserve Index Predicting Hypoxemia
After obtaining the approval of the hospital ethics committee, this prospective, observational study included written informed consent from 51 participants with 19<BMI<25 m/kg2 and 51 participants with BMI>40 m/kg2 undergoing an…
- Trial name
- NCT05480748
- Testing
- monitoring
- Where
- Turkey (Türkiye)
- Volunteers
- 51 people
- Sponsor
- Dr. Lutfi Kirdar Kartal Training and Research Hospital
COVID, SARS-CoV-2
European/Euro-ELSO Survey on Adult and Neonatal/ Pediatric COVID-19 Patients in ECMO
In the last 10 years, severe acute respiratory infection (SARI) was responsible of multiple outbreaks putting a strain on the public health worldwide.
- Conditions
- COVID, SARS-CoV-2, ARDS, Human, Refractory Hypoxemia
- Trial name
- EuroECMO-COVID (NCT04366921)
- Where
- 97 sites in Austria, Belgium and 17 more
- Volunteers
- 150 people
- Sponsor
- Maastricht University Medical Center
Airway Management, Tracheal Extubation
Interest of Tracheal Extubation in Positive Pressure on Postoperative Oxygenation in Adult Digestive Surgery
Evaluation of a postoperative tracheal extubation protocol under positive pressure in accordance with international recommendations.
- Conditions
- Airway Management, Tracheal Extubation, Postoperative Respiratory Complications, Postoperative Hypoxemia
- Trial name
- ExPress (NCT04381949)
- Testing
- positive pressure extubation
- Where
- France
- Volunteers
- 208 people
- Sponsor
- University Hospital, Rouen
Acute Hypoxemia
Building Respiratory Support in East Africa Through High Flow Versus Standard Flow Oxygen Evaluation
Acute hypoxemia is common and deadly in resource variable settings. While studies in high income countries (HICs) have indicated a possible benefit to high flow oxygen as compared with standard flow oxygen, rigorous studies in…
- Trial name
- BREATHE (NCT05754034)
- Testing
- High flow oxygen, Standard flow oxygen
- Where
- 5 sites in Kenya, Malawi and 1 more
- Volunteers
- 1,600 people
- Sponsor
- Beth Israel Deaconess Medical Center
H1N1 Pneumonia, Hypoxemia
Rapamune Improves Outcomes of Severe H1N1 Pneumonia
Severe H1N1 pneumonia with acute respiratory failure shows hyperactive immune cells infiltration of lung. Rapamune, a mTOR inhibitor, modulates the immune response by blocking activation of T- and B-cells.
- Trial name
- NCT01620307
- Testing
- Sirolimus (Rapamune 2mg/day, Pfizer)
- Volunteers
- 38 people
- Sponsor
- Chang Gung Memorial Hospital
Hypoxemia
Influence of Intermittent Hypoxia on Glycemic Control
The aim of this research project is to determine the effect of intermittent hypoxia on glucose uptake in response to an oral glucose tolerance test in healthy individuals, individuals with prediabetes and patients with type 2…
- Trial name
- NCT06490900
- Testing
- Intermittent hypoxia, Intermittent normoxia
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Desaturation, Hypoxemia
Prevention of Desaturations Using Positive Airway Pressure or Capnometry During ERCP
Although sedation during endoscopy is sufficiently safe, desaturations are among the most common side effects of endoscopic retrograde cholangiopancreatography (ERCP) procedures, occurring in approximately 20-30% of cases.
- Conditions
- Desaturation, Hypoxemia, ERCP
- Trial name
- PrePAP-ERCP (NCT07056075)
- Testing
- Nasal PAP Ventilation System, Low Flow Oxygen, Capnometry
- Where
- 2 sites in Austria
- Volunteers
- 288 people
- Sponsor
- Karl Landsteiner University of Health Sciences
Sleep Apnea, Obstructive Sleep Apnea
Prevalence, Phenotypes, Predictors and Prognostic Implication of Obstructive Sleep Apnea in Pulmonary Hypertension
The investigators propose a prospective, observational study to determine the impact of OSA and associated physiological parameters on clinical outcomes in patients with pulmonary hypertension.
- Conditions
- Sleep Apnea, Obstructive Sleep Apnea, Pulmonary Hypertension, Epidemiology
- Trial name
- POSAPH (NCT05595200)
- Testing
- Level III portable sleep study
- Where
- China
- Volunteers
- 480 people
- Sponsor
- Chinese Pulmonary Vascular Disease Research Group
Hypoxemia, Hypercapnia
The Physiological Impact of N95 Masks on Medical Staff
Wearing N95 masks may have adverse physical effect on medical staff
- Trial name
- NCT00173017
- Testing
- wearing N95 masks
- Where
- Taiwan
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital