Clinical trials: Hypothyroidism
Hypothyroidism
Study to Verify Clinical Utility of Point-of-Care (POC) Thyroid Stimulating Hormone (TSH) Test Kits as Compared to Third Generation TSH Test Kit
This is a Phase 4, single-center, open-label, interventional study, wherein all enrolled subjects will be tested for Thyroid Stimulating Hormone (TSH) by using the quantitative and the qualitative Point-of-Care (POC) TSH test…
- Trial name
- NCT01921452
- Testing
- Quantitative POC TSH Kit, Qualitative POC TSH Kit, Third generation TSH Kit
- Where
- China
- Volunteers
- 283 people
- Sponsor
- Merck KGaA, Darmstadt, Germany
Myocardial Infarction, Hypothyroidism
Thyroid Hormone Replacement for Hypothyroidism and Acute Myocardial Infarction(ThyroHeart-AMI)
Based on accumulating evidences showing that hypothyroid status is associated with poor prognosis among acute myocardial infarction (AMI) patients, the study is designed to evaluate whether replacement treatment with…
- Trial name
- NCT02512978
- Testing
- Levothyroxine
- Where
- China
- Volunteers
- 160 people
- Sponsor
- Chinese Academy of Medical Sciences, Fuwai Hospital
Hypothyroidism
Clinical Efficacy of Darqeen Capsule for the Management of Hypothyroidism Associated with Female Reproductive Hormonal Imbalance
STUDY OBJECTIVES 1. To assess the safety of Darqeen capsule for the management of Hypothyroidism 2. Evaluate the efficacy of Darqeen capsule for the management of Hypothyroidism 3.
- Trial name
- NCT06826248
- Testing
- Darqeen Capsule
- Where
- Pakistan
- Volunteers
- 50 people
- Sponsor
- Hamdard University
Hypothyroidism
Dosing of LT4 in Older Individuals
Our overall goal is to determine the clinical consequences of allowing greater flexibility in LT4 dosing in older individuals who take LT4.
- Trial name
- DOT4 (NCT06073665)
- Testing
- Levothyroxine Sodium
- Where
- United States
- Volunteers
- 228 people
- Sponsor
- University of Pennsylvania
Thyroid Diseases, Chronic Periodontitis
Thyroid Disease and Chronic Periodontitis
Currently, the investigators are unaware of any previous studies that have analyzed the relationship between the prevalence of thyroid disease and chronic periodontitis among adults utilizing a retrospective, cross-sectional…
- Trial name
- NCT03369405
- Testing
- NO intervention, patient records review only
- Where
- United States
- Volunteers
- 4,965 people, healthy volunteers welcome
- Sponsor
- University at Buffalo
Heart Injuries
Subclinical Hypothyroidism and Acute Anterior Myocardial Infarction: Is it Cardio-protective or Not?
The study plans to investigate whether recovery of the heart function after acute anterior myocardial infarction is dependent upon improvement in thyroid gland functioning.
- Trial name
- NCT03017157
- Testing
- Echo-cardiogram, Blood test
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Hillel Yaffe Medical Center
Congenital Hypothyroidism
TG Gene Mutations and Congenital Hypothyroidism
The aim of this study was to identify mutations in the thyroglobulin gene that might be present in patients with fetal goiter and congenital goiter hypothyroidism.
- Trial name
- NCT00493103
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Hypothyroidism, Subclinical Hypothyroidism
Thyroid Disorders in Malaysia: A Nationwide Multicentre Study
This will be a population based study looking at the prevalence of thyroid disorders in Malaysia (including hypo- and hyperthyroidism, subclinical hypo- or hyperthyroidism) and its association with different ethnicity and iodine…
- Conditions
- Hypothyroidism, Subclinical Hypothyroidism, Hyperthyroidism, Subclinical Hyperthyroidism
- Trial name
- MyEndo-Thyroid (NCT02190214)
- Volunteers
- 2,498 people, healthy volunteers welcome
- Sponsor
- International Islamic University Malaysia
Child Development Disorders, Pregnancy
The Effect of Thyroid Hormone Levels in Pregnant Women on the Intelligence Quotient (IQ) of Their Children
This study is designed to test the hypothesis that the level of the thyroid hormone thyroxine (specifically, free thyroxine, FT4) circulating in the blood of pregnant women is the key thyroid-related factor to influence early…
- Conditions
- Child Development Disorders, Pregnancy, Subclinical Hypothyroidism
- Trial name
- NCT00147433
- Where
- United States
- Volunteers
- 5,000 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Iodine Deficiency, Goiter
The Effects of Iodized Salt on Cognitive Development in Ethiopia
Many school children in Ethiopia and their mothers are known to be iodine deficient. Prevalence in the Amhara region is around 29%.
- Conditions
- Iodine Deficiency, Goiter, Cretinism
- Trial name
- NCT01349634
- Testing
- Iodized salt
- Where
- Canada
- Volunteers
- 5,704 people, healthy volunteers welcome
- Sponsor
- McGill University
Fatigue, Hypothyroidism
The Effect of Aroma on Fatigue Scores Among Women With Hypothyroidism
This study evaluates the effects of an inhaled blend of essential oils on fatigue scores among women who have hypothyroidism. Half of the participants will receive an essential oil blend to inhale daily for two weeks while the…
- Trial name
- NCT03465176
- Testing
- Aromatherapy Blend
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Nutraceuticals Research Institute
Hypothyroidism Primary
The Effect of Dietary Supplements for Pregnant Women on Levothyroxine Absorption
Hypothyroidism is a common disease that is successfully treated with the replacement of thyroid hormones in the form of levothyroxine.
- Trial name
- NCT04988802
- Testing
- Prenatal Nutrients Solgar
- Where
- Croatia
- Volunteers
- 37 people
- Sponsor
- University Hospital Dubrava
Graves' Disease
Post-Radioiodine Graves' Management: The PRAGMA-Study
Thyroid dysfunction following radioiodine for Graves' disease is common, potentially detrimental and avoidable. A variety of clinical strategies are employed in the post-radioiodine era util the patient is on a stable thyroid…
- Trial name
- PRAGMA (NCT01885533)
- Where
- 2 sites in United Kingdom
- Volunteers
- 803 people
- Sponsor
- Newcastle-upon-Tyne Hospitals NHS Trust
Comparison of Aerobic Exercise and Resistance Training
Comparison of Aerobic and Resistance Training on Exercise Capacity, Depression and Quality of Life in Hypothyroidism.
the study will show the effects of aerobic and resistance training on exercise capacity, depression and quality of life in patients with hypothyroidism.
- Trial name
- NCT06377826
- Testing
- aerobic exercises, resistance training, medication
- Where
- Pakistan
- Volunteers
- 66 people
- Sponsor
- Riphah International University
NAFLD
NAFLD in Patient of Hypothyroidism
Nonalcoholic fatty liver disease (NAFLD) is the most important chronic liver disease in the western world, affecting almost 30% of the general population.
- Trial name
- NCT05813301
- Volunteers
- 100 people
- Sponsor
- Assiut University
Hypothyroidism, Osteoporosis
Awareness of Osteoporosis in Patients With Hypothyroidism
Osteoporosis is a condition that describes compromised skeletal microarchitecture in general, with clinical signs of decreased bone mineral density. Patients with hypothyroidism are at increased risk for developing osteoporosis.
- Conditions
- Hypothyroidism, Osteoporosis, Osteoporosis Risk
- Trial name
- NCT05760131
- Testing
- Patient Participation Form
- Volunteers
- 400 people
- Sponsor
- Uskudar State Hospital
Lymphoma
Revlimid® Capsules Drug Use-results Surveillance (Relapsed or Refractory ATLL)
To understand the safety and efficacy of Revlimid® Capsules 2.5 mg and 5 mg (hereinafter referred to as Revlimid) under actual conditions of use in patients with relapsed or refractory adult T-cell leukemia lymphoma (hereinafter…
- Trial name
- NCT03098589
- Testing
- Revlimid
- Where
- Japan
- Volunteers
- 1,149 people
- Sponsor
- Celgene
Total Thyroidectomy, Hyperthyroidism
Evaluation of Levothyroxine Replacement Therapy After Total Thyroidectomy Using a Smart Wristband
The goal of this observational study is to determine whether nighttime heart rate and heart rhythm data collected by a smart wristband can identify under- or over-replacement with levothyroxine before the routine 1-month thyroid…
- Conditions
- Total Thyroidectomy, Hyperthyroidism, Hypothyroidism
- Trial name
- SMART-THY (NCT07733375)
- Testing
- Xiomi Smart Band 10
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Yeditepe University Hospital
Hypothyroidism
Effects of Thyroid Hormone Withdrawal on Metabolic Parameters During Radioactive Iodine Therapy in Thyroid Cancer
1. The incidence of differentiated thyroid cancer is increasing in Korea. A significant number of them experience severe hypothyroidism in preparation for radioactive iodine (RAI) therapy after total thyroidectomy. 2.
- Trial name
- NCT01744769
- Where
- South Korea
- Volunteers
- 80 people
- Sponsor
- Konkuk University Medical Center
Hypothyroidism, Hyperthyroidism
Pharmacist Role in Thyroid Disorders
Hypothyroidism (HoT) treatment involves lifelong thyroxine replacement therapy and regular monitoring. The objective of this study was to assess the impact of clinical pharmacist (CP) intervention in managing drug-related…
- Conditions
- Hypothyroidism, Hyperthyroidism, Thyroid Diseases
- Trial name
- NCT06408909
- Testing
- Clinical Pharmacist Intervention Group
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people
- Sponsor
- Istanbul University - Cerrahpasa