Clinical trials: Hypotension on Induction
Spinal Anaesthesia Induced Hypotension
Role of Ondansetron in Spinal Anaesthesia Induced Hypotension
The objective of this study is to determine the effect of ondansetron on the total consumption of norepinephrine infusion needed to prevent spinal anaesthesia induced hypotension in cesarean section.
- Trial name
- NCT06727201
- Testing
- Ondansetron (Zofran)
- Where
- Egypt
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Assiut University
Hypotension, Anesthesia
Methohexital v Propofol as General Anesthetic in Patients on ACEIs or ARBs
Patient undergoing general anesthesia in elective surgery will be assigned to receive either methohexital or propofol general anesthesia.
- Trial name
- NCT02624050
- Testing
- Methohexital, Propofol
- Where
- United States
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Hypotension, Tachycardia
Processing and Effects of Cannabis
The purpose of this study is to investigate the processing of cannabis, and to investigate the occurrence of effects of cannabis on the cardiovascular system and the central nervous system; at higher levels of exposure.
- Trial name
- NCT00225407
- Testing
- Smoking of cannabis cigarettes (different strength)
- Where
- Netherlands
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- UMC Utrecht
Hypotension Drug-Induced, Cerebral Oxygen Saturation
Effect of Controlled Hypotension on Cerebral Oxygen Saturation
For a successful functional endoscopic sinus surgery (FESS), it is crucial to provide effective controlled hypotension to reduce blood loss and provide a relatively blood-free surgical environment to facilitate surgery.
- Trial name
- NCT02967029
- Testing
- Esmolol Hydrochloride, Remifentanil Hydrochloride
- Where
- Turkey (Türkiye)
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Hypotension on Induction
Carotid Artery Corrected Flow Time and Respiratory Variation of Blood Flow Peak Velocity for Prediction of Hypotension After Induction of General Anaesthesia in Adult Patients With Chronic Liver Disease
Baseline Measurements For the ultrasound parameters, it is the average of three readings In supine position . The investigators will continuously monitoring during induction and 10 minutes after.
- Trial name
- NCT07370103
- Where
- Egypt
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Cirrhosis, Liver, Acute-On-Chronic Liver Failure
20% Albumin vs. Balanced Salt Solution as Resuscitation Fluid in Cirrhosis With Sepsis Induced Hypotension
Patients with cirrhosis patients have a high incidence of sepsis which can trigger decompensation and may result in prolonged hospital stay and increased mortality.
- Conditions
- Cirrhosis, Liver, Acute-On-Chronic Liver Failure, Shock, Septic, Shock Hypovolemic
- Trial name
- NCT05441878
- Testing
- 20% albumin, Balanced salt solution
- Where
- India
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Hypotension on Induction
Effect of Carotid Ultrasound-guided Fluid Management on Anesthetic-induced Hypotension in Elderly Patients Undergoing Gastrointestinal Surgery
The goal of this clinical trial is to learn about Whether carotid ultrasound guided fluid management can reduce the incidence of hypotension after general anesthesia induction in elderly patients undergoing gastrointestinal…
- Trial name
- NCT05891951
- Testing
- Fluid therapy under the guide of Carotid ultrasound
- Where
- China
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Min Su
Hypotension on Induction
The Role of Left Ventricular Outflow Tract (LVOT) Velocity-time Integral (VTI) and Respiratory Variability at Peak Rate (Vpeak) in Predicting Hypotension After General Anesthesia Induction
Preoperatively, patients will undergo transthoracic echocardiography measurements approximately 15-30 minutes before induction. TTE will be performed on all patients by an experienced observer; the echocardiography device will be…
- Trial name
- LVOT-VTI-hypot (NCT07121699)
- Testing
- Inotrope
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Aydin Adnan Menderes University
Hypotension on Induction
Perfusion Index as a Predictor of Postinduction Hypotension of General Anesthesia in Geriatric Patients
The influence of hemodynamic aberrations during anesthesia on adverse outcomes is an important clinical issue. There is evidence that hypotension and hypertension during general anesthesia are independently associated with…
- Trial name
- NCT04682717
- Testing
- perfusion index monitoring for postinduction hypotension
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cairo University
Phenylephrine, Cesarean Birth
Comparison of Two Different Doses of Phenylephrine on Oxytocin Hemodynamic Effect
Cesarean section is one of the commonly performed surgical procedures in the world. Once baby is delivered during the surgical procedure anesthesiologist administer Oxytocin drug through IV cannula which helps the Uterus to…
- Trial name
- NCT07420127
- Testing
- Phenylephrine bolus 75 micrograms, Phenylephrine bolus 50 micrograms
- Where
- Pakistan
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Rawalpindi Medical College
Spinal Anesthesia
Effect of Vasopressors on Spinal Anaesthesia Induced Hypotension
160 pregnant patients will be enrolled in this study. Participants will divide in to 4 groups. Spinal anaesthesia will perform with 5% marcain heavy 2 ml+20 microgram fentanyl to the all patients.
- Trial name
- NCT03163914
- Testing
- Epinephrine, Norepinephrine, Phenylephrine
- Where
- Turkey (Türkiye)
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Peripheral Perfusion, Postoperative Pain
Effects Magnesium Sulfate and Labetalol Infusion on Peripheral Perfusion and Pain in Nasal Surgeries
One of main risk of controlled hypotension during nasal surgeries is impaired perfusion. Peripheral perfusion of non-vital organs usually impaired earlier than vital organs.
- Trial name
- NCT04688203
- Testing
- Magnesium Sulfate Injection, Labetalol Injectable Solution
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Cesarean Section, Preoperative Anxiety
Effects of Sedation on Spinal Anesthesia-induced Maternal Hypotension
Background: This study was designed to investigate the effect of sedation on the occurrence of maternal hypotension in preoperatively anxious parturients undergoing urgent category-1 Cesarean section (C/S) under spinal…
- Conditions
- Cesarean Section, Preoperative Anxiety, Spinal Anesthesia, Sedation
- Trial name
- NCT02732197
- Testing
- Sedation, No sedation
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Van Training and Research Hospital
Vascular Stiffness, Hypotension on Induction
The Relationship Between BCM, Arterial Stiffness and Hemodynamic Instability During Induction of General Anesthesia
Arterial hypotension during induction of general anesthesia is a risk factor for developing postoperative cardiovascular complications.
- Conditions
- Vascular Stiffness, Hypotension on Induction, Anesthesia; Reaction
- Trial name
- NCT03237429
- Testing
- bioimpedance spectroscopy
- Where
- Romania
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Grigore T. Popa University of Medicine and Pharmacy
Hypotension on Induction
PPV for Predicting PIH in the Elderly
The purpose of this observational study is to investigate the predictive power of pulse pressure variability during forced inhalation（PPVfi） on the occurrence of hypotension in elderly patients after induction of general…
- Trial name
- PPVfi-PIH (NCT07166562)
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Second Xiangya Hospital of Central South University
Post Induction Hypotension
Effects of Esketamine and Bilateral Lower Limb Elevation on Hemodynamic Stability During Induction of General Anesthesia in Elderly Patients Undergoing Thoracic Surgery
Video-assisted thoracoscopic surgery (VATS) is widely used in thoracic surgery due to small incisions, low stress response, and high patient tolerance.
- Trial name
- NCT07374458
- Testing
- Esketamine, Bilateral Lower Limb Elevation
- Volunteers
- 292 people, healthy volunteers welcome
- Sponsor
- Nanjing First Hospital, Nanjing Medical University
Hypovolemia
Effect of Preoperative Fluid Therapy on Post-induction Hypotension
Although preoperative dehydration is a known risk factor for post-induction hypotension, evidence regarding preemptive weight-based fluid therapy remains limited.
- Trial name
- NCT06231472
- Testing
- weight-based fluid therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Mustafa Burgac
Hypotension on Induction
Analyzing the Relationship Between Speed Propofol is Given and Low Blood Pressure
The objective of this study is to evaluate the hemodynamic changes related to Propofol administration rate. We hypothesize that slow administration of IV propofol will have less hemodynamic disturbances and will require less…
- Trial name
- NCT05415436
- Testing
- Propofol slow administration
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Toledo
Intraoperative Hypotension, Jugular Veins
Internal Jugular Vein Ultrasound and Acute Kidney Injury After Abdominal Surgery
This observational study aims to learn whether changes in the internal jugular vein during anesthesia induction can help predict low blood pressure and kidney injury after surgery. The main questions it aims to answer are: 1.
- Conditions
- Intraoperative Hypotension, Jugular Veins, Hypotension on Induction, General Anesthesia With Propofol
- Trial name
- PRO-JUGULAR (NCT07638306)
- Testing
- Internal Jugular Vein Ultrasound Assesment
- Where
- Romania
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Tîrgu Mureș Emergency Clinical County Hospital, Romania
Anesthesia, Spinal, Cesarean Section
Post Spinal Anesthesia Hypotension and Preoperative Hydration
Study of the impact of preoperative oral rehydration on the incidence of spinal anesthesia-induced hypotension for scheduled cesarean section.
- Trial name
- NCT04450667
- Testing
- Nutricia PreOp
- Where
- Belgium
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Brugmann University Hospital