Clinical trials: Hypopnea Syndrome
Heart Failure, Sleep Apnea Syndromes
Treatment of Sleep Disordered Breathing In Acute Decompensated Heart Failure Patients
Heart Failure affects 5-6 million Americans and there are about 550 thousand new cases of heart failure every year. There are approximately 3 million hospital admission for acute decompensated heart failure with hospital…
- Trial name
- ARIA-II (NCT00804349)
- Testing
- Autotitrating Positive Airway Pressure
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Albert Einstein Healthcare Network
Obstructive Sleep Apnea (OSA), Polysomnography
Multimodal Deep Learning Model for Predicting the Apnea-Hypopnea Index in Obstructive Sleep
This study aims to develop a multimodal deep learning model that integrates noninvasive signals to predict the severity of obstructive sleep apnea.
- Trial name
- NCT07447999
- Testing
- electronic stethoscope, fingertip pulse oximeter, pressure-sensing mattresses
- Where
- Taiwan
- Volunteers
- 150 people
- Sponsor
- Fu Jen Catholic University
Endometriosis, Obstructive Sleep Apnea-hypopnea
Assessment of the Occurrence of Obstructive Sleep Apnea Hypopnea Syndrome (OSAHS) in Women Suffering from Endometriosis
This observational study aims at establishing the proportion of patients suffering from endometriosis and for whom an Obstructive Sleep Apnea Hypopnea Syndrome (OSAHS) diagnosis is established.
- Trial name
- ENDOSAS (NCT06060756)
- Testing
- questionnaires completion
- Volunteers
- 80 people
- Sponsor
- Elsan
OSA
Effects of Lemborexant as a Treatment for Moderate-to-severe OSA Patients With Low Arousal Threshold
The goal of this randomized, placebo-controlled, double-blind, crossover trial (1-week wash out period) is to compare 1 night of 5 mg Lemborexant to placebo administered before sleep in 10 moderate to severe OSA patients with low…
- Trial name
- LOSALAT (NCT05763329)
- Testing
- Lemborexant 5 MG Oral Tablet [Dayvigo] Day 1, Lemborexant 5 MG Oral Tablet [Dayvigo] Day 2
- Where
- Thailand
- Volunteers
- 10 people
- Sponsor
- Chulalongkorn University
Obstructive Sleep Apnea, Transverse Maxillary Deficiency
Obstructive Sleep Apnea Hypopnea Syndrome (OSAHS) and Transverse Orthodontic Deficiency in Children
OSAHS (Obstructive Sleep Apnea Hypopnea Syndrome) in children is a frequent respiratory disorder, whose prevalence is estimated at between 1.2 and 5.7%, and which, if left untreated, can cause severe medical complications.
- Trial name
- ASCOT (NCT07086612)
- Testing
- over nigtht ventilatory polysomnograph test
- Where
- France
- Volunteers
- 102 people
- Sponsor
- Fondation Hôpital Saint-Joseph
Obstructive Sleep Apnea-hypopnea Syndrome
Physical Activity Level in Patients With OSAS During Covid-19 Pandemic
As long as the people stay at home because of the Covid 19 outbreak, the investigators assume that the sleep quality of OUAS patients, like everyone else, and the sleep quality of COVID-19 outbreak are reduced due to anxiety and…
- Trial name
- NCT04451993
- Where
- Turkey (Türkiye)
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Ahi Evren Chest and Cardiovascular Surgery Education and Research Hospital
Sleep Apnea, Cardiovascular Diseases
Oxidative Stress and Cardiovascular Morbidity in Sleep Apnea-Hypopnea Syndrome (SAHS)
The purpose of this study is to compare the levels of 8-isoprostane and other oxidative stress biomarkers in plasma and condensed exhaled air between patients with SAHS and cardiovascular complications, patients with SAHS without…
- Trial name
- OSCAMSA (NCT00487929)
- Testing
- nasal CPAP
- Where
- Spain
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hospital Universitario La Paz
Obstructive Sleep Apnea
Nightly Wearable Monitoring During Home-Based Submental Electrical Stimulation for Obstructive Sleep Apnea
This single-arm pilot study evaluates the feasibility of nightly wearable monitoring with a ring-type sleep monitor during a 4-week home-based program of submental transcutaneous neuromuscular electrical stimulation in adults…
- Trial name
- NCT07921329
- Testing
- Submental transcutaneous neuromuscular electrical stimulation (RS-18), Ring-type sleep monitor (Belun Ring BLS-100)
- Where
- Taiwan
- Volunteers
- 50 people
- Sponsor
- E-DA Hospital
Obstructive Sleep Apnea, OSA
Treating Obstructive Sleep Apnea Using Targeted Hypoglossal Neurostimulation
Multi-center, open-label, prospective, randomized clinical trial of the aura6000(R) System for the reduction of apnea and hypopneas in adult patients with moderate to severe obstructive sleep apnea who have failed or are…
- Conditions
- Obstructive Sleep Apnea, OSA, Apnea, Apnea, Obstructive
- Trial name
- OSPREY (NCT04950894)
- Testing
- Hypoglossal Nerve Stimulation
- Where
- 19 sites in United States
- Volunteers
- 107 people
- Sponsor
- LivaNova
Obstructive Sleep Apnea
Obstructive Sleep Apnea and Comprehensive Remotely-supervised Rehabilitation Program
The purpose of this study is to investigate the feasibility and effect of a 12-week remotely-supervised rehabilitation program in male patients between 25-65 years old with newly diagnosed obstructive sleep apnea with…
- Trial name
- NCT04759456
- Testing
- Remotely-supervised rehabilitation program
- Where
- Czechia
- Volunteers
- 60 people
- Sponsor
- Brno University Hospital
Sleep Apnea, Obstructive
The Effects of Trazodone on Sleep Apnea Severity
In Obstructive sleep apnea (OSA), the upper airway closes over and over again during sleep. This leads to disrupted sleep (waking up during the night), daytime sleepiness, and an increased risk for developing high blood pressure.
- Trial name
- NCT01817907
- Testing
- Trazodone
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Brigham and Women's Hospital
Obstructive Sleep Apnea
Predicting Cardiometabolic Risk in Mild-to-Moderate Obstructive Sleep Apnea: Inflammation vs. Apnea/Hypopnea Index
The purpose of the study is to compare the relative contribution of systemic inflammation vs. Obstructive Sleep Apnea (OSA) severity (as measured by Apnea Hypopnea Index) in predicting cardiovascular and metabolic aberrations…
- Trial name
- NCT03062748
- Where
- United States
- Volunteers
- 196 people
- Sponsor
- Milton S. Hershey Medical Center
Narcolepsy, Sleep Apnea, Obstructive
PROVIGIL® (Modafinil) Treatment in Children and Adolescents With Excessive Sleepiness Associated With Narcolepsy or Obstructive Sleep Apnea/Hypopnea Syndrome
The primary objective of the study is to evaluate the safety and tolerability of treatment with PROVIGIL in children and adolescents with excessive sleepiness (ES) associated with narcolepsy or OSAHS (obstructive sleep…
- Trial name
- NCT00107848
- Testing
- Modafinil
- Where
- 61 sites in United States, Canada
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- Cephalon
Obstructive Sleep Apnea Hypopnea Syndrome (OSAHS), Head and Neck Cancers
Innovative OSA Screening in Head and Neck Cancer Patients With the Apneal App
Obstructive sleep apnea syndrome is a common but often underdiagnosed condition, with significant impacts on quality of life, such as fatigue, attention disorders, and an increased risk of heart attack or stroke.
- Trial name
- NCT06896448
- Testing
- Specialized sleep consultation and overnight recording using the APNEAL application
- Where
- France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Caen
Obstructive Sleep Apnoea
Dynamic Alterations of Tongue in Sleep Apnoea Hypopnea Syndrome During Sleep
The aim of this study was to evaluate the dynamic changes of the tongue in patients with obstructive sleep apnoea hypopnea syndrome (OSAHS) during sleep and while awake by using Ultrafast Magnetic Resonance Imaging (UMRI)
- Trial name
- NCT01687855
- Testing
- Ultrafast Magnetic Resonance Imaging
- Where
- China
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Wenzhou Medical University
Hypertensive Disorder of Pregnancy, Sleep Apnea, Obstructive
Positive Airway Pressure Treatment of Obstructive Sleep-disordered Breathing in Hypertensive Disorders of Pregnancy
The purpose of this study is to conduct a pilot randomized, controlled trial to evaluate the feasibility and obtain pilot outcome data for a subsequent definitive trial evaluating the effects of postitive airway pressure (PAP)…
- Trial name
- NCT03309826
- Testing
- Positive Airway Pressure, Nasal Dilator Strip
- Where
- Canada
- Volunteers
- 48 people
- Sponsor
- Dr John Kimoff