Clinical trials: Hypopigmented Skin
Cross Syndrome
Comparison of Stretching and MET in Lower Cross Syndrome
The aim of the study is to compare the effects of stretching exercises \& muscle energy techniques in the management of lower cross syndrome and to find the effective treatment in the lower cross syndrome management.
- Trial name
- NCT04668040
- Testing
- Muscle energy technique, Stretching
- Where
- Pakistan
- Volunteers
- 58 people
- Sponsor
- Riphah International University
Vitiligo
Vitiligo Extent Score (VES) Score in Comparison to Vitiligo Area and Severity Index (VASI) Score
All patients with vitiligo attending dermatology outpatient clinic at Kasr Alainy Teaching Hospital will be enrolled in this study to compare VES and VASI scores and evaluate them as assessment methods
- Trial name
- NCT03411135
- Testing
- VES and VASI scores as assessment methods for vitiligo
- Volunteers
- 101 people
- Sponsor
- Cairo University
Phototherapy, Vitiligo
Maintenance Therapy of Narrow-band UV-B Therapy in Patients With Vitiligo
Although vitiligo is difficult to cure, recurrences are frequent after treatment, and many patients suffer from concerns about recurrence as well as disease.
- Conditions
- Phototherapy, Vitiligo, Maintenance Therapy, Narrow-band UV-B
- Trial name
- NCT03384342
- Testing
- Narrow-band UV-B therapy
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- The Catholic University of Korea
Non-segmental Vitiligo
A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of VYN201 Gel in Subjects With Non-segmental Vitiligo.
The purpose of this study is to evaluate the efficacy, safety, and pharmacokinetics of VYN201 Gel in subjects with non-segmental vitiligo.
- Trial name
- NCT06493578
- Testing
- VYN201 Gel, Vehicle Gel
- Where
- 49 sites in United States, Canada
- Volunteers
- 205 people
- Sponsor
- Vyne Therapeutics Inc.
Vitiligo
Safety and Tolerability Study of Cerdulatinib Gel, 0.37% in Adults With Vitiligo
This is a phase 2a, randomized, double-blind, vehicle-controlled study to assess the safety, tolerability, and systemic exposure of cerdulatinib gel, 0.37% in adults with vitiligo
- Trial name
- NCT04103060
- Testing
- Cerdulatinib 0.37% gel, Vehicle gel
- Where
- 2 sites in United States
- Volunteers
- 33 people
- Sponsor
- Dermavant Sciences GmbH
Gingival Pigmentation
Microneedling With Vitamin C Versus Injectable Vitamin C for Depigmentation in Gingival Melanin Hyperpigmentation
The study is a randomized controlled clinical trial comparing the use of microneedling with vitamin C against injecting vitamin C for depigmentation in physiological gingival melanin hyperpigmentation in a group of patients…
- Trial name
- NCT05786885
- Testing
- Microneedling will be done with application of topical vitamin C paste for depigmentation, Vitamin C injection
- Volunteers
- 22 people
- Sponsor
- Cairo University
Vitiligo, Depigmented Scars
Comparative Study Using Dermabrasion vs CO2 Laser & Collagen Dressing vs Vaseline Gauze in MKTP
The purpose of this study is to: 1. Compare two different techniques in the melanocyte keratinocyte transplant procedure: Use of carbon dioxide laser versus use of dermabrasion 2.
- Conditions
- Vitiligo, Depigmented Scars, Depigmentation
- Trial name
- MKTP (NCT02038257)
- Testing
- MKTP (melanocyte keratinocyte transplant procedure), Collagen Dressing, Vaseline Impregnated Gauze
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Henry Ford Health System
Vitiligo Vulgaris
Efficacy and Safety of Pimecrolimus for the Treatment of Vitiligo Vulgaris
Patients with vitiligo vulgaris are treated with Pimecrolimus twice a day during 6 months. After a baseline visit, patient returns for a control visit after 3 and 6 months of treatment.
- Trial name
- NCT00372307
- Testing
- Application of pimecrolimus
- Where
- Belgium
- Volunteers
- 26 people
- Sponsor
- University Hospital, Ghent
Vitiligo
Comparing Recipient Site Preparation Using Dermabrasion, Dermaroller and Liquid Nitrogen Induced Blister in Non Cultured Epidermal Cell Suspension in Stable Vitiligo
A COMPARATIVE STUDY BETWEEN RECEPIENT SITE PREPARATION USING DERMABRASION, LIQUID NITROGEN INDUCED BLISTER AND DERMAROLLING SYSTEM IN AUTOLOGOUS NON CULTURED EPIDERMAL CELL SUSPENSION PROCEDURE IN STABLE VITILIGO PATIENTS
- Trial name
- NCT03668834
- Testing
- Dermabrasion with NCES, Dermaroller with NCES, Liquid nitrogen induced blister with NCES
- Where
- India
- Volunteers
- 36 people
- Sponsor
- Post Graduate Institute of Medical Education and Research, Chandigarh
Vitiligo
The Value of Adding Mini-oral Pulse Steroid Therapy in Preventing Peri-lesional Halo Post Non-cultured Epidermal Cell Suspension (NCES) in Cases With Stable Segmental and Non-acral Vitiligo.
The goal of this clinical trial is to learn if adding mini-oral pulse steroid therapy improves the results of non-cultured epidermal cell suspension (NCES) surgery in patients with stable vitiligo.
- Trial name
- NCT07472816
- Testing
- Non-cultured epidermal cell suspension (NCES) surgery, Oral mini pulse, Excimer Sessions
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
SCAD, Addison Disease
Spontaneous Coronary Artery Dissection (SCAD) and Autoimmunity
This case control study aims to determine whether spontaneous coronary artery dissection (SCAD) is associated with autoimmune diseases and to update the incidence of SCAD in a population-based cohort.
- Conditions
- SCAD, Addison Disease, Ankylosing Spondylitis, Antiphospholipid Antibody Syndrome
- Trial name
- NCT03941184
- Where
- United States
- Volunteers
- 114 people
- Sponsor
- Mayo Clinic
Vitiligo
Atorvastatin in Active Vitiligo
Condition: Non segmental and active vitiligo of adulthood. Main objective: To evaluate the efficacy of a daily treatment with atorvastatin 80mg/d combined to UVB compared to UVB alone in active vitiligo after 6 months of…
- Trial name
- NCT02432534
- Testing
- Atorvastatin, UVB
- Where
- 2 sites in France, Indonesia
- Volunteers
- 28 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Vitiligo
Virus Early Transcription Factor (VETF) Multicenter Phototherapy Protocol
Background Phototherapy UVB TL01 currently represents the first choice in treatment to induce the repigmentation of vitiligo spots.
- Trial name
- VETF (NCT00525395)
- Testing
- Sequential phototherapy, Continuous phototherapy
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- Istituti Fisioterapici Ospitalieri
Vitiligo
Prostaglandin F2-alpha (PGF2α) in Vitiligo
study the cutaneous expression of PGF2α in vitiligo patients and compare it with normal control subjects.
- Trial name
- NCT03755830
- Testing
- Skin biopsy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Postural; Defect
Effect of Pilates on Balance and Spinal Curvature In Upper Crossed Syndrome
The study will be conducted to investigate the effect of Pilates exercise on spinal curvature and balance in patients with the upper cross syndrome. .
- Trial name
- UCS (NCT05591729)
- Testing
- Pilates exercises, postural correction exercise
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Upper Cross Syndrome
Effects of Post Isometric Relaxation With Scapular Stabilization Exercises
The levator scapulae is an important postural muscle that tends to shorten or become tight because of overactivity and bad posture, leading to neck and shoulder pain.
- Trial name
- NCT05973682
- Testing
- Post-isometric relaxation and Conventional treatment, Conventional Physical Therapy
- Where
- Pakistan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Hermanski-Pudlak Syndrome, Colitis
Medical Treatment of Colitis in Patients With Hermansky-Pudlak Syndrome
This study will determine if medical treatment of colitis (inflammation of the colon resulting in loose bowel movements, rectal bleeding, and belly pain) that is used for other colitis conditions, such as Crohn's disease and…
- Conditions
- Hermanski-Pudlak Syndrome, Colitis, Cytokines, Lymphocytes
- Trial name
- NCT00514982
- Testing
- Mesalamine, Infliximab, Corticosteroids
- Where
- United States
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Vitiligo
A Proof of Concept, Phase 1 Study of CGB-600 for the Topical Treatment of Non-Segmented Facial Vitiligo
The goal of this clinical trial is to learn if drug CGB-600 works to treat vitiligo on the face and neck in participants between 18-60 years of age. It will also learn about the safety of CGB-600.
- Trial name
- NCT07357870
- Testing
- Drug: CGB-600 gel, experimental drug
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- CAGE Bio Inc.
Upper Crossed Syndrome
Effect of Cervicothoracic Mobilization on Upper Crossed Syndrome
PURPOSE: To investigate the effect of cervicothoracic mobilization on Craniovertebral angle (CVA), sagittal shoulder angle (SSA), kyphotic angle and pain intensity level in upper crossed syndrome.
- Trial name
- NCT05665296
- Testing
- cervicothoracic mobilization, CCE
- Volunteers
- 60 people
- Sponsor
- Cairo University
Vitiligo, Treatment
Efficacy of Intralesional Triamcinolone Injection in the Treatment of Vitiligo
A randomized split-body pilot study was planned to confirm efficacy of intralesiona triamcinolone injection in patients with vitiligo
- Conditions
- Vitiligo, Treatment, Intralesional Injection, Corticosteroid
- Trial name
- NCT03365141
- Testing
- Triamcinolone acetonide 0.4mg/cc, Phototherapy (NBUVB or excimer laser), Topical tacrolimus
- Where
- South Korea
- Volunteers
- 12 people
- Sponsor
- The Catholic University of Korea