Clinical trials: Hypoperfusion
Hypotension and Shock, Hypoperfusion
Non-invasive Objective Assessment of Hemodynamics in Preterm Neonates
Study type: Prospective Observational trial Study design: Longitudinal Population: Preterm newborns <32 weeks gestational age Hypothesis: The inclusion of non-invasive physiological measures of cardiac output, peripheral…
- Conditions
- Hypotension and Shock, Hypoperfusion, Hemodynamic Instability, Intraventricular Hemorrhage
- Trial name
- NOAH (NCT04538079)
- Testing
- Multimodal objective non-invasive Monitoring
- Where
- Ireland
- Volunteers
- 56 people
- Sponsor
- University College Cork
Lactate, Metabolism
Lactate Metabolism in the Hypoperfused Critically Ill
Investigating lactate metabolism in critically ill patients whom are hypoperfused by preforming metabolomics via liquid chromatography-mass spectrometry.
- Conditions
- Lactate, Metabolism, Hypoperfusion, Metabolomics
- Trial name
- NCT05582824
- Testing
- Blood and urine test
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- University of Copenhagen
Cerebral Hypoperfusion
Real-Time Decision Support for Improving Intraoperative Cerebral Perfusion Pressure
Across broad surgical populations, cerebral hypoperfusion is associated with increased mortality, stroke, brain cellular injury, and poor functional outcomes.
- Trial name
- NCT03285971
- Testing
- Electronic CPP pager alert
- Where
- United States
- Volunteers
- 53 people
- Sponsor
- University of Michigan
Intrauterine Growth Retardation, Feeding Patterns
The Effect of Neonatal Feeding Modalities on Splanchnic Oxygenation
OBJECTIVES: The main purpose of this study was to evaluate the impact of drip versus intermittent feeding on splanchnic oxygenation in preterm infants with intrauterine growth restriction (IUGR).
- Conditions
- Intrauterine Growth Retardation, Feeding Patterns, Splanchnic Hypoperfusion
- Trial name
- NCT05513495
- Testing
- The effect of drip versus intermittent feeding on splanchnic oxygenation
- Where
- Turkey (Türkiye)
- Volunteers
- 51 people
- Sponsor
- Ozge Surmeli Onay
Acute Kidney Injury, Hypoperfusion
The Predictive Performance of Renal Ultrasound on Changes in Renal Clearance
The study will examine the ability of renal ultrasound (Doppler and Contrast Enhanced Ultrasound (CEUS)) in distinguishing ICU patients who exhibit increases in glomerular filtration rate (GFR) in response to fluid loading, from…
- Conditions
- Acute Kidney Injury, Hypoperfusion, Fluid Overload
- Trial name
- NCT04198168
- Testing
- IV crystalloid fluid bolus
- Where
- Denmark
- Volunteers
- 2 people
- Sponsor
- Aarhus University Hospital
Premedication, Endotracheal Intubation
Cerebral NIRS Profiles During Premedication for Neonatal Intubation
Observational ancillary study of the PRETTINEO study (ClinicalTrials.gov Identifier: NCT01490580) which is a multicenter double blind randomized controlled trial comparing "atropine+propofol" vs "atropine+atracurium+sufentanil"…
- Conditions
- Premedication, Endotracheal Intubation, Cerebral Hypoperfusion
- Trial name
- NCT02700893
- Testing
- atropine+ propofol, atropine + atracurium + sufentanil
- Where
- 2 sites in France
- Volunteers
- 28 people
- Sponsor
- Centre Hospitalier Intercommunal Creteil
Infant, Premature, Hypoperfusion in Newborn
Monitoring of Systemic or Organ Perfusion for Preterm Infants
To investigate biomarker reflects systemic or specific organ perfusion well, we are going to the observational comparison study using several hemodynamic monitoring methods in the premature infants.
- Conditions
- Infant, Premature, Hypoperfusion in Newborn, Necrotizing Enterocolitis of Newborn, Sepsis Newborn
- Trial name
- NCT03136172
- Testing
- NIRS (near Infra-red spectroscopy)
- Where
- South Korea
- Volunteers
- 85 people
- Sponsor
- Inha University Hospital
Identify the Presence of a Marker of Ischemia/Hypoperfusion of the Brain Via Peripheral Blood, Ischemia/Hypoperfusion of Brain
Biomarkers of Ischemia: Xanthine, Hypoxanthine and Inosine Levels During Carotid Stenting Procedures
The purpose of the study is to determine if a new blood test can help the doctor determine if there is brain injury or ischemia. Ischemia occurs when not enough oxygen gets to the brain.
- Trial name
- NCT01639534
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Virginia Commonwealth University
Hypoperfusion
Using Fluorescence Angiography to Detect Occult Shock
The purpose of this study is to determine if fluorescence angiography can detect occult shock (hypoperfusion).
- Trial name
- NCT02846727
- Testing
- skin perfusion image
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Yale University
Hypovolemia, Renal Hypoperfusion
Evaluation of Hemodynamics and Amount of Blood Flowing Through the Kidneys by Measuring Some Physiological Substances in Blood and Urines
The purpose of this study is to verify any existing relationship between mixed oxygen saturation (from central venous catheter) and urinary sodium, potassium, chloride in determining the volemic state and renal perfusion of…
- Trial name
- NCT01650103
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- Azienda Ospedaliera di Padova
Hypovolemia During Liver Transplantation, Renal Hypoperfusion During Liver Transplantation
Evaluation of Hemodynamics and Amount of Blood Flowing Through the Kidneys During Liver Transplant by Measuring Some Physiological Substances in Blood and Urines
The purpose of this study is to verify any existing relationship between urinary parameters (such as excretion of sodium, chlorine, urinary partial CO2 pressure [PuCO2]) and general volemic indicators (such as PiCCO, ScvO2, O2…
- Trial name
- NCT01650116
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- Azienda Ospedaliera di Padova
Heart Failure, Dilated Cardiomyopathy
Brain Function and Perfusion in Patients With Heart Failure
The investigators will evaluate the determinants of cerebral impairment in patients with non-ischemic heart failure compared to controls, and its relation to cognitive function.
- Conditions
- Heart Failure, Dilated Cardiomyopathy, Perfusion, Cognitive Impairment
- Trial name
- BRAIN-HF (NCT01756014)
- Where
- Netherlands
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University Medical Center Groningen
Gastrointestinal, Hypoperfusion
Effects of Citrulline on Gut Functioning During Excercise
During exercise, splanchnic perfusion is compromised, resulting in organ damage in healthy individuals. Improving the availability of NO might result increase splanchnic perfusion and prevent organ damage during exercise.
- Conditions
- Gastrointestinal, Hypoperfusion, Gut Damage
- Trial name
- NCT01239303
- Testing
- Citrulline, alanine
- Where
- Netherlands
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Carotid Stenosis, Hypoperfusion
Physiological Magnetic Resonance Imaging (MRI) to Improve Carotid Endarterectomy Outcomes
The carotid arteries are blood vessels in the neck that supply blood to the brain. Carotid stenosis disease is defined as a narrowing of these arteries due to the build up of plaque.
- Conditions
- Carotid Stenosis, Hypoperfusion, Transient Ischemic Attack
- Trial name
- NCT01272843
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- Sunnybrook Health Sciences Centre
Brain Hypoperfusion
Hydroxyethyl Starch 130/0.4 and Sodium Chloride Injection as Adjunctive Therapy in Subjects With Internal Carotid Artery Hypoperfusion
The aim of this study is to evaluate the effectiveness, safety and tolerability of consistent dosages of the study drug (hydroxyethyl starch 130/0.4 and sodium chloride injection, Vuloven) administrated intravenously for 7 days.
- Trial name
- NCT01192581
- Testing
- hydroxyethyl starch 130/0.4 and sodium chloride injection
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Xijing Hospital
Brain Hypoperfusion Syndrome, Ischemia Brain
Efficiency Study of Siwu Tang to Treat Brain Hypoperfusion Syndrome
Brain hypoperfusion patients may cause vascular dementia results from their hypoperfusion state except that is a risk factor for stroke.
- Trial name
- NCT01221662
- Testing
- Siwu Tang
- Where
- Taiwan
- Volunteers
- 80 people
- Sponsor
- China Medical University Hospital
Left Ventricular Dysfunction, Coronary Artery Bypass Surgery
Laboratory Outcome Predictors in Coronary Surgery
Evaluate less employed markers of tissue hypoperfusion as venoarterial carbon dioxide partial pressure difference (ΔPCO2) and estimated respiratory quotient (eRQ) combined to other classically studied markers as predictive…
- Conditions
- Left Ventricular Dysfunction, Coronary Artery Bypass Surgery, Tissue Hypoperfusion
- Trial name
- NCT01178866
- Where
- Brazil
- Volunteers
- 87 people
- Sponsor
- University of Sao Paulo