Clinical trials: Hypoglycemia (Diabetic)
Type 1 Diabetes Mellitus (T1DM), Diabetes Distress
GlycoQuest: An AI-Adaptive CGM-Integrated Serious Game for Pediatric Type 1 Diabetes
Type 1 diabetes diagnosed in childhood requires rapid acquisition of complex self-management skills while children and caregivers are also adapting emotionally and socially to a chronic condition.
- Conditions
- Type 1 Diabetes Mellitus (T1DM), Diabetes Distress, Hypoglycemia (Diabetic), Family Conflict
- Trial name
- GlycoQuest (NCT07726680)
- Testing
- GlycoQuest Digital Therapeutic, Enhanced Digital Psychoeducation
- Where
- Pakistan
- Volunteers
- 110 people
- Sponsor
- Shifa International Hospital
Diabetes Mellitus
Effect of Pulsatile IV Insulin on Circulating Risk Markers of Vascular and Metabolic Complications in Pts With Diabetes
The purpose of this study is to determine the effect of Pulsatile Intravenous Insulin therapy on circulating blood markers. These blood markers are selected due to their correlation to and possible pathogenetic roles in vascular…
- Trial name
- NCT00361907
- Testing
- Effect of Pulsatile IV insulin on diabetic pt blood markers, Effect of Pulsatile IV Insulin on blood markers
- Where
- United States
- Volunteers
- 105 people
- Sponsor
- Florida Atlantic University
Diabetes Mellitus, Type 2
Dosage Reduction and Acute Glycemic Complications in People With Type 2 Diabetes Who Fast During Ramadan
Every lunar year, during the month of Ramadan, Muslims abstain from food and drink between dawn and nightfall. People with type 2 diabetes who fast during Ramadan are at an increased risk of acute glycemic complications.
- Trial name
- NCT04237493
- Testing
- Metformin and Glimepiride (Low Dosage), Metformin and Vildagliptin (Low Dosage), Metformin and Insulin Glargine U100 (Low Dosage)
- Where
- Jordan
- Volunteers
- 687 people
- Sponsor
- University of Jordan
Diabetes Mellitus, Hypoglycemia (Diabetic)
Continuous Bloodsugar Monitoring System With a Sensor Compared to Fingerstick Bloodsugar Monitoring
This clinical trial aims to compare a continuous glucose monitoring system with traditional fingerstick blood glucose monitoring.
- Conditions
- Diabetes Mellitus, Hypoglycemia (Diabetic), Hypoglycemia Night, Hyperglycemia
- Trial name
- GLUCOSENS (NCT06473480)
- Testing
- Abbott FreeStyle Libre System 2 Plus, Abbott Freestyle Libre Pro
- Where
- 2 sites in Denmark
- Volunteers
- 329 people
- Sponsor
- Odense University Hospital
Infants of Diabetic Mothers, Placenta
Placental Weight in Infants of Gestational Diabetic Mothers
This prospective cross-sectional study examined the relationship between placental weight and early neonatal outcomes, such as blood glucose levels within the first 24 hours and early neonatal morbidities in infants born to…
- Conditions
- Infants of Diabetic Mothers, Placenta, Hypoglycaemia
- Trial name
- NCT07765784
- Testing
- Blood Glucose Level
- Where
- Turkey (Türkiye)
- Volunteers
- 98 people
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Diabetes Mellitus Type 2
Vildagliptin vs Sitagliptin add-on to Insulin - Impact on Glycemic Profile and Correlation of Hypoglycemic Episodes and Heart Function
Vildagliptin and Sitagliptin both belong to the class of DPP-4 inhibitors, but differ in their pharmacokinetic profile as well as in their approved application (Vildagliptin, 2x 50 mg daily, Sitagliptin, 1x 100 mg daily).
- Trial name
- CGM-VISIT (NCT01686932)
- Testing
- Vildagliptin, Sitagliptin
- Where
- 11 sites in Germany
- Volunteers
- 51 people
- Sponsor
- Novartis Pharmaceuticals
Hypoglycemia, Hypoglycemia Acute
Electronic Platform for Diabetic Patients Activation
The purpose of this study is to assess the efficacy of an electronic platform for doctor-patient communication in order to reduce severe and non-severe hypoglycemia events as well as inadvertent hypoglycemia events.
- Trial name
- INSULINCOM (NCT04595383)
- Testing
- ti.care
- Volunteers
- 106 people
- Sponsor
- Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana
Diabetes, Diabetes Mellitus, Type 1
Comparison of Insulin Detemir and NPH With Respect to Lowering the Blood Sugar and Symptoms Experienced by Type 1 Diabetics During Hypoglycaemia
This trial is conducted in UK. The aim of this clinical trial is to investigate lowering the blood sugar and symptoms experienced during hypoglycaemia
- Trial name
- NCT00760448
- Testing
- insulin detemir, insulin NPH
- Where
- United Kingdom
- Volunteers
- 25 people
- Sponsor
- Novo Nordisk A/S
Type 2 Diabetes Mellitus, Colonoscopy
Abnormal Blood Sugar Tests in Diabetic Patients During Colonoscopy Preparation
Type 2 diabetes is rapidly increasing globally and has been associated with an increased risk of colorectal cancer. Therefore, the numbers of diabetic patients who will undergo colonoscopic screening are expected to grow…
- Trial name
- NCT03109951
- Testing
- Colonoscopy preparation using polyethylene glycol
- Where
- South Korea
- Volunteers
- 187 people, healthy volunteers welcome
- Sponsor
- Catholic Kwandong University
Acute Coronary Syndrome, Type 2 Diabetes
Evaluation of Continuous Glucose Monitoring in Patients With ACS and Type 2 Diabetes in ICU
The investigators hypothesize that the use of a continuous glucose monitoring system (CGMS) can reduce glycemic variability assessed by coefficient of variation (CV) during the acute phase of acute coronary syndrome (ACS) in…
- Trial name
- EVASION (NCT04822740)
- Testing
- Control Glucose Monitoring System
- Where
- France
- Volunteers
- 2 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Neonatal Hypoglycemia, Infant, Small for Gestational Age
Effect of Tahneek on Hypoglycemia in Newborn Infants
Tahneek is an Arabic word which means putting something sweet such as dates, in the infant's mouth after the birth. Neonatal hypoglycemia is common in the first few days after birth.
- Conditions
- Neonatal Hypoglycemia, Infant, Small for Gestational Age, Macrosomia, Fetal, Intrauterine Growth Restriction
- Trial name
- THIN (NCT03726697)
- Testing
- Tahneek
- Where
- Saudi Arabia
- Volunteers
- 324 people
- Sponsor
- King Abdullah International Medical Research Center
Obstetric Labor, Pregnancy in Diabetics
Intrapartum Glucose and Insulin Compared to Glucose Alone in Diabetic Women
This study aims to examine the effect of intrapartum treatment of diabetic women with combined glucose and constant insulin infusion compared to glucose alone on the incidence of neonatal hypoglycemia.
- Trial name
- NCT03273881
- Testing
- glucose solution and Insulin, glucose solution only
- Where
- Israel
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- HaEmek Medical Center, Israel
Infant, Newborn, Diseases, Pregnancy in Diabetics
Diazoxide In the Management Of Hypoglycemic Neonates
Diazoxide is an oral hyperglycemic medication. Diazoxide has been proven effective for treating hypoglycemia in infants and children with some types of persistent hyperinsulinemic hypoglycemia.
- Conditions
- Infant, Newborn, Diseases, Pregnancy in Diabetics, Infant, Diabetic Mother, Hypoglycemia
- Trial name
- DIMOHN (NCT00994149)
- Testing
- Diazoxide, Ora-plus
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- University of Saskatchewan
Diabetes, Diabetes Mellitus, Type 1
Liraglutide as add-on to Insulin in Type 1 Diabetes
The purpose of this study is to: Part 1: To investigate how 12 weeks treatment with liraglutide affects glycemic control in poorly controlled patients and how the treatment affects gastric emptying rate during hypoglycemia.
- Trial name
- T1DMLIRA (NCT02092896)
- Testing
- Liraglutide
- Where
- Denmark
- Volunteers
- 40 people
- Sponsor
- Hvidovre University Hospital
Type 1 Diabetes Mellitus
Efficacy of Islet After Kidney Transplantation
Type 1 diabetes is an autoimmune disease in which the insulin-producing pancreatic beta cells are destroyed, resulting in poor blood sugar control.
- Trial name
- NCT00468117
- Testing
- Islet transplantation, Antithymocyte Globulin, Daclizumab or Basiliximab
- Where
- 10 sites in United States, Canada
- Volunteers
- 24 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
End-Stage Kidney Disease, Type 2 Diabetes Mellitus
Glucose Containing and Glucose Free Hemodialysate in Type 2 Diabetic Patients
The purpose of this study is to investigate differences in glycemia during the whole hemodialysis day and the whole freeday during hemodialysis, during the evening and the night after hemodialysis and at the same time intervals…
- Trial name
- NCT02009514
- Testing
- Glucose-containing compared to glucose-free hemodialysate
- Volunteers
- 10 people
- Sponsor
- Tampere University Hospital
Hypoglycemia, Diabetes Mellitus, Type 1
Comparison Between Hypoglycemic Counter Regulatory Responses in Type 1 Diabetics vs Control Subjects
This study compares the hypoglycemic counter regulatory response in type 1 diabetics and in healthy control subjects with and without antecedent hypoglycemia
- Trial name
- NCT03034226
- Testing
- Glucose clamp technique
- Where
- Denmark
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Old Age, Institutionalized in EHPAD (French Nursing Home)
Screening for Hypoglycemia in an Institutionalized Elderly Diabetic Population.
Diabetes is a major public health problem that has been growing steadily in recent years. Its prevalence is very high in the elderly, in whom there is an increased risk of hypoglycemia.
- Conditions
- Old Age, Institutionalized in EHPAD (French Nursing Home), Diabetes, Hypoglycemic Syndrome
- Trial name
- HAGED (NCT03656887)
- Testing
- Continuous interstitial glucose sensor, Sensor Scan
- Where
- France
- Volunteers
- 29 people
- Sponsor
- Centre Hospitalier Universitaire Dijon
Hyperglycaemia (Diabetic)
Development of Agents to Diminish the Risk of Hypoglycemia-induced Brain Injury in Type 1 Diabetes
To determine the effect of re-activation of brain glucose metabolism induced by dichloroacetate (DCA) on cognitive function and counterregulatory hormone responses in patients with type 1 diabetes (T1DM) with recurrent…
- Trial name
- NCT03356457
- Testing
- Dichloroacetate
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Yale University
Diabetes Mellitus, Type 1 Diabetes, Cardiovascular Diseases (CVD)
Relationship Between Insulin Dose and Complications in Type 1 Diabetes
The goal of this observational study is to better understand how the amount of insulin people with type 1 diabetes are using relates to blood glucose control and the risk of complications.
- Conditions
- Diabetes Mellitus, Type 1 Diabetes, Cardiovascular Diseases (CVD), Severe Albuminuria, Estimated Glomerular Filtration Rate (eGFR)
- Trial name
- iDose-EDC (NCT07911033)
- Testing
- Routine/prescribed exogenous insulin dose
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Rachel Miller