Clinical trials: Hypertrophic Scars
Scars, Hypertrophic
Treatment of Fibrotic Scars With Rapid Acoustic Pulse (RAP) Device
A multi-treatment proof of concept clinical study is to evaluate the safety, and efficacy of multiple treatments with Soliton's Rapid Acoustic Pulse (RAP) device for the improvement in the appearance of fibrotic scars
- Trial name
- NCT04702529
- Testing
- Treatment of hypertrophic scars (Soliton's Rapid Acoustic Pulse (RAP) Device)
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Soliton
Scar, Hypertrophic
Intralesional Treatment of Keloids
Intralesional injection in treatment of keloid
- Trial name
- NCT06729840
- Testing
- Injection
- Where
- Egypt
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Sohag University
Hypertrophic Scars
Using Skin Blood Flow to Measure the Effect of Different Doses of Negative Pressure Therapy
Introduction. Skin blood flow (SBF) is crucial for transporting nutrients during healing to treat scarring. Negative pressure therapy (NPT) is a promising option to enhance SBF.
- Trial name
- Negative press (NCT06690749)
- Testing
- Negative pressure therapy, NPT
- Where
- Taiwan
- Volunteers
- 36 people
- Sponsor
- Asia University
Hypertrophic Scars, Burn Scar Patients
Effect of PRF & Fractional CO2 Laser in Postburn Hypertrophic Scars
Recent advancements in scar management include the use of Plasma Rich Fibrin (PRF) injections and fractional CO2 laser treatments.
- Trial name
- NCT06664268
- Testing
- Plasma rich in growth factors (PRGF-Endoret), Fractional CO2 laser assisted PDT
- Volunteers
- 30 people
- Sponsor
- Assiut University
Acne Scars - Mixed Atrophic and Hypertrophic, Acne
Pilot Study Investigating the Efficacy of Fat Grafting as a Treatment for Male and Female Facial Acne Scarring
This single-center, clinical trial consists of a one autologous fat grafting treatment followed by 3-month and 6-month post-treatment visits in order to assess the efficacy of fat grafting when used by men and women with facial…
- Trial name
- NCT04559022
- Testing
- Fat Grafting
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Hypertrophic Scars
Electromotive Drug Administration of Magnesium Sulphate on Hypertrophic Scar
In this study 80 patients will be randomly assigned into two equal groups (40 patients for each group): 1. Group A: Experimental: Magnesium Sulphate Iontophoresis for Postburn Hypertrophic Scar The study group includes 40…
- Trial name
- NCT06649188
- Testing
- Magnesium Sulphate Iontophoresis, traditional physical therapy program
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Cairo University
Scar Tissue, Hypertrophic Scar
Effectiveness of Dry Needling in Linear Scar Tissue
Scar tissue can cause serious complications that significantly impact a patient's quality of life. Common complications include stiffness and contractions, which can restrict joint mobility and make daily activities challenging.
- Conditions
- Scar Tissue, Hypertrophic Scar, Hypertrophic Scar of Upper Arm (Disorder), Hypertrophic Surgical Scar
- Trial name
- NCT06033430
- Testing
- True dry needling
- Where
- 2 sites in United States, Iran
- Volunteers
- 80 people
- Sponsor
- Iran University of Medical Sciences
Acne Scars - Mixed Atrophic and Hypertrophic, Scar
Impact of Tripolar Radiofrequency on Acne Scar
The aim of this study is to investigate the therapeutic efficacy of tripolar radiofrequency on acne scar
- Conditions
- Acne Scars - Mixed Atrophic and Hypertrophic, Scar, Radiofrequency
- Trial name
- NCT06492356
- Testing
- Tripolar radiofrequency therapy, medical treatment
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Scars, Hypopigmented Scar
Treatment of Hypopigmented Scars With Bimatoprost
Patients who have hypo-pigmented burn scar will have two scars chosen and randomized to treated scar and control scar. The subject will then have both scars treated with fractional ablative CO2 laser (FLSR).
- Conditions
- Scars, Hypopigmented Scar, Hypopigmented Skin, Burn Scar
- Trial name
- NCT06122090
- Testing
- Bimatoprost, Saline
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Medstar Health Research Institute
Acne Scars - Mixed Atrophic and Hypertrophic, Ice Pick Scars
Evaluation of Efficacy and Safety of HCC_45 for the Correction of Acne Scars of the Face
Acne scars represent a frequent complication of moderate/severe acne and may negatively impact on psychosocial and physical well-being of acne patients.
- Conditions
- Acne Scars - Mixed Atrophic and Hypertrophic, Ice Pick Scars, Rolling Scars, Boxcar Scars
- Trial name
- NCT05691049
- Testing
- HCC_45
- Where
- Italy
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- IBSA Farmaceutici Italia Srl
Hypertrophic Scar
Effect of Nd-YAG Laser on Hypertrophic Scar
A hypertrophic scar is a serious health concern in the industrialized world. Two groups of patients were treated with standard medical care. The experimental group received additional laser therapy.
- Trial name
- Nd-YAG (NCT06347081)
- Testing
- Nd- YAG laser at 532nm wavelength
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Hypertrophic Scar
Study to Evaluate Efficacy of OLX10010 in Reducing Recurrence of Hypertrophic Scarring After Scar Revision Surgery
Phase 2a, prospective, randomized, double-blind, intra-subject, placebo-controlled, proof of concept study. Approximately twenty subjects will be randomized 1:1 to one of two treatment arms: Arm A: 2.0 mg/cm OLX10010 biweekly…
- Trial name
- NCT04877756
- Testing
- OLX10010
- Where
- 6 sites in United States
- Volunteers
- 22 people
- Sponsor
- Olix Pharmaceuticals, Inc.
Hypertrophic Scar
Hypertrophic Scar Prevention by Novel Topical Gel Application
Researchers are trying to find out more about the side effects of topical (applied to the skin) Pentamidine, to determine if it is safe for use in people.
- Trial name
- NCT03403621
- Testing
- Pentamidine Isethionate
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Mayo Clinic
Acne Scars - Mixed Atrophic and Hypertrophic
Safety and Efficacy of Sofwave Treatment for Acne Scars Appearance Improvement
Open-label, non-randomized, prospective, multi-center, self-controlled clinical study with masked evaluation.
- Trial name
- NCT05358860
- Testing
- Sofwave
- Where
- 4 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sofwave Medical LTD
Burn Scar, Hypertrophic Scar
Characterization of Dyschromic Hypertrophic Scar
Currently, there are limited prevention or treatments available for dyschromia in burn hypertrophic scars (HTSs). The limited available techniques involve transferring melanocytes from unaffected areas to the scar to adjust…
- Conditions
- Burn Scar, Hypertrophic Scar, Hyperpigmentation, Hypopigmented Scar
- Trial name
- NCT04619589
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Medstar Health Research Institute
Acne Scars - Mixed Atrophic and Hypertrophic
Safety and Efficacy Investigation on the Effects of ClearSkin Non-ablative ER:Glass 1540nm Laser Module in the Treatment of Acne Scars.
The ClearSkin module, Er: Glass 1540nm, is largely used in the treatment of acne vulgaris and acne scars. The non-ablative ER:Glass 1540 nm laser deeply penetrates the skin, causing thermal damage to the sebaceous glands…
- Trial name
- NCT06102343
- Testing
- Alma Harmony
- Where
- Portugal
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Alma Lasers
Hypertrophic Scar
Clinical Investigation to Evaluate the Performance of Hyaluronic Acid for the Treatment of Hypertrophic Scars
The study includes two study groups, one involves treatment with auto-cross-linked Hyaluronic acid by intralesional and hypodermic injection, repeated after two weeks (T14), while the control arm provides an equal treatment but…
- Trial name
- NCT04614415
- Testing
- Autocrosslinked Hyaluronic aid
- Where
- 4 sites in Italy
- Volunteers
- 78 people
- Sponsor
- Fidia Farmaceutici s.p.a.
Acne Scars - Mixed Atrophic and Hypertrophic
Clinical Evaluation of the Safety and Performance of FRF for the Treatment and Reduction of Acne Scarring
Prospective, single centre, evaluator-blind study of the safety and performance of fractional radiofrequency (RF) for the treatment and reduction of acne scarring.
- Trial name
- NCT04827680
- Testing
- Venus Viva MD
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Venus Concept
Acne Scars - Mixed Atrophic and Hypertrophic
enLighten Laser With MLA Handpiece for Treatment of Moderate and Severe Acne Scars
The purpose of this pivotal investigation is to evaluate the efficacy and safety of the Cutera enlighten multi-wavelength 532 nm and 1064 nm Nd:YAG picosecond pulse duration laser and an investigational micro-lens array (MLA)…
- Trial name
- NCT03284333
- Testing
- other
- Where
- 2 sites in United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Cutera Inc.
Hypertrophic Scar
Botulinum Toxin Type a Iontophoresis for Postburn Hypertrophic Scar
The goal of this clinical trial study: is to determine the effect Botulinum toxin type A iontophoresis in hypertrophic scars for post burned patients.
- Trial name
- NCT05771623
- Testing
- Iontophoresis drug delivery device, Traditional physical therapy
- Where
- Egypt
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Cairo University