Clinical trials: Hypertension (HTN)
Post-induction Hypotension (PIH), Hypertension (HTN)
Hemodynamic Effects of Lithotomy Position in Surgical Patients (PH-LITHO)
Anesthesia-induced hypotension is a common occurrence in elderly hypertensive patients and is closely associated with increased postoperative morbidity This study aims to investigate whether the lithotomy position, a…
- Conditions
- Post-induction Hypotension (PIH), Hypertension (HTN), Geriatric Anesthesia
- Trial name
- PIH-LITHO (NCT07549152)
- Testing
- Pre-induction Lithotomy Position, Standard Supine Position
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Trabzon Karadeniz Teknik Universitesi
Atrial Fibrillation (AF), Hypertension (HTN)
Out-of-office Monitoring for Rhythms Of Normal Versus Atrial Fibrillation
The goal of this clinical trial is to learn if screening for atrial fibrillation (AFib), a common irregular heart rhythm, through daily home blood pressure monitoring will decrease the time to atrial fibrillation diagnosis in…
- Conditions
- Atrial Fibrillation (AF), Hypertension (HTN), High Blood Pressure
- Trial name
- OMRON-AF (NCT07582523)
- Testing
- Blood Pressure Monitor Without AFib Detection, Blood Pressure Monitor With AFib Detection
- Where
- United States
- Volunteers
- 1,910 people
- Sponsor
- University of California, San Francisco
Vascular Stiffness, Hypertension (HTN)
Low Energy Availability and Hypertension in Division I HBCU Athletes
Low energy availability (LEA) occurs when the body does not get enough calories to support both daily life and exercise. This can happen when athletes train hard but do not eat enough to match their energy needs.
- Conditions
- Vascular Stiffness, Hypertension (HTN), Nutritional Deficiency Related Cardiovascular Risk in Athletes
- Trial name
- CORE-DI (NCT07583940)
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- North Carolina Agriculture & Technical State University
Hypertension (HTN)
Automatically Transmitted Home Blood Pressure and Automated Patient Feedback in Hypertension Care: the AUTO 2 Trial
The purpose of this study is to evaluate the effectiveness of automatically-generated medical advice to patients about to their home blood pressure monitoring results sent through patient portal messages compared to no automated…
- Trial name
- AUTO 2 (NCT07397260)
- Testing
- Self report of home measured blood pressure via patient EHR portal, Automated feedback about home blood pressure results, Automated Transmission of Remotely Measured Blood Pressure
- Where
- United States
- Volunteers
- 1,304 people
- Sponsor
- Northwestern University
Type 2 Diabetes Mellitus (T2DM), Hypertension (HTN)
Cohort Study of Metabolic Disease and Hypertension
The goal of this observational study is to learn how type 2 diabetes and high blood pressure develop over time in adults in Mexico.
- Trial name
- NCT07577063
- Testing
- Observational Study
- Where
- Mexico
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- Coordinación de Investigación en Salud, Mexico
Blood Pressure Monitoring, Hypertension (HTN)
Community Health Worker Coaching to Reduce Cardiovascular Risk Among Women After a Hypertensive Disorder of Pregnancy
The goal of this clinical trial is to find out whether an enhanced program works better than remote blood pressure monitoring (RBPM) alone for women who had high blood pressure during pregnancy.
- Conditions
- Blood Pressure Monitoring, Hypertension (HTN), Pregnancy
- Trial name
- HERHEART (NCT07457970)
- Testing
- Enhanced Care Group, Remote Blood Pressure Monitoring alone
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- University of South Carolina
Hypertension (HTN), Pre Hypertension
The Effects of Brief Periods of Exercise on Blood Pressure
High blood pressure is a common medical condition that affects the body's arteries. It's also called hypertension. Untreated hypertension increases the risk of heart attack, stroke and other serious health problems.
- Trial name
- NCT07453550
- Testing
- wall-squat, wall-squat-tradition
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Hartford
Hypertension (HTN), Type 2 Diabetes
Integrating Care for Hypertension-Diabetes MULTImorbidity in Guatemala Through HEARTS Implementation
The purpose of this study is to find out whether a program called HEARTS can improve care for people who have both high blood pressure and diabetes.
- Trial name
- MULTI-HEARTS (NCT07536919)
- Testing
- HEARTS implementation strategies, Supply chain strengthening
- Volunteers
- 1,440 people
- Sponsor
- University of Michigan
Hypertension (HTN)
A Phase I Clinical Study of ART101 Injection in Healthy Adult Subjects
This is a Phase I clinical study, which is a randomized, double-blind, placebo-controlled, single-dose, dose-escalation study. The purpose of this study is to evaluate the safety, tolerability, pharmacokinetics (PK), and…
- Trial name
- NCT07529600
- Testing
- Subcutaneous (SC) single dose
- Where
- 2 sites in China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Arnatar Therapeutics, Inc.
Hypertension (HTN)
WEARABLE-BP: Wearable Everyday Automated Readings to Enable Assessment of Blood Pressure Control
The WEARABLE-BP study will evaluate the clinical value of obtaining continual measurements using the Aktiia G1 Optical Blood Pressure Monitoring (OBPM) device in hypertensive patients, compared to using a traditional upper arm…
- Trial name
- WEARABLE-BP (NCT07523269)
- Testing
- Aktiia G1 BP monitor for 12 months, Traditional BP monitor for 6 months / Aktiia G1 BP monitor for 6 months
- Where
- United States
- Volunteers
- 164 people
- Sponsor
- Aktiia SA
Hypertension (HTN), Age More 60yr
Empirical Study on Lifestyle Intervention for Elderly Hypertensive Patients in Community Based on TTM Theory
This study intervention is based on TTM theory and implements lifestyle interventions, including nutritious diet, regular exercise, social support, sleep optimization, avoidance of addictive substances, and stress management.
- Trial name
- NCT07492290
- Testing
- Lifestyle medicine
- Volunteers
- 106 people
- Sponsor
- Qu Shen
Hypertension (HTN), Hyperhomocysteinemia
Homocysteine and Early Diastolic Dysfunction in Newly Diagnosed Hypertension
This prospective single-center observational study aims to evaluate the relationship between elevated plasma homocysteine levels and early echocardiographic abnormalities in patients with newly diagnosed essential hypertension.
- Conditions
- Hypertension (HTN), Hyperhomocysteinemia, Diastolic Dysfunction
- Trial name
- HHT-EDD (NCT07480265)
- Testing
- Homocysteine Measurement and Echocardiography
- Where
- Turkey (Türkiye)
- Volunteers
- 500 people
- Sponsor
- Necmettin Erbakan University
Hypertension (HTN)
NR and Exercise for Blood Pressure
Hypertension continues to pose a significant global health challenge, with rates of optimal blood pressure control remaining low - particularly in China, where fewer than 5% of individuals with hypertension achieve…
- Trial name
- NCT07475208
- Testing
- Brisk walking, Nicotinamide Riboside 1000 mg
- Volunteers
- 112 people
- Sponsor
- ZHANG Jiaqi
Hypertension (HTN), Cardiometabolic Diseases
Genetic Architecture of Natriuretic Peptides and Blood Pressure Response
Natriuretic peptides (NPs) are hormones produced by the heart and play an important role in maintaining cardiovascular health and have favorable metabolic benefits.
- Trial name
- NCT07118592
- Testing
- Low Salt Diet, High Salt Diet, Saline Infusion
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Hypertension (HTN), Diabetes (DM)
Community Health Workers Led Integrated Management of Hypertension and Diabetes in Nepal
Hypertension (HTN) and diabetes mellitus are significant global public health challenges, contributing to 13.5% of premature deaths, 54% of incident strokes, and 47% of coronary heart disease cases (HTN), and increasing risks of…
- Trial name
- NCT07432126
- Testing
- Integrated management of hypertension and diabetes using group care approach
- Where
- Nepal
- Volunteers
- 398 people
- Sponsor
- Kathmandu University School of Medical Sciences
Hypertension, Hypertension (HTN)
Effects of Beetroot Extract on Blood Pressure and Exercise in Hypertensive Older Women
The goal of this clinical trial is to learn about the acute effects of beetroot extract in older women with high blood pressure.
- Trial name
- NCT07444138
- Testing
- Beetroot Extract (Nitrate-rich), Exercise, Rest (Control Condition)
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- São Paulo State University
Hypertension (HTN), Diarrhea
Mortality Control Program for Economically Productive Age Group in Tribal Area of Melghat.
Background: Age specific mortality rate (ASMR) of 16-60 years is very high in Indian tribal areas due to communicable and non-communicable diseases.
- Conditions
- Hypertension (HTN), Diarrhea, Pneumonia, Malaria Fever
- Trial name
- MCPEPAG (NCT07436104)
- Testing
- Trained village health workers (VHWs) , provided treatment of HTN, diarrhoea, malaria, pneumonia, asthma and COPD by Amlodipine, ORS, Norfloxacin, Chloroquine, Azithromycin, salbutamol rotacaps, Appropriate referral
- Where
- India
- Volunteers
- 72,564 people, healthy volunteers welcome
- Sponsor
- MAHAN Trust
Laparascopic Sleeve Gastrectomy, Obesity & Overweight
Impact Of Laparoscopic Sleeve Gastrectomy On Obesity-Related Comorbidities In Patients Over 65 Years
This study compares laparoscopic sleeve gastrectomy (a type of weight-loss surgery) with non-surgical care in adults aged 65 or older who have severe obesity and related health problems like type 2 diabetes, high blood pressure…
- Conditions
- Laparascopic Sleeve Gastrectomy, Obesity & Overweight, Obesity Type 2 Diabetes Mellitus, Obstructive Sleep Apnea (OSA)
- Trial name
- NCT07437716
- Testing
- Laparoscopic Sleeve Gastrectomy (LSG), Structured Dietary Counseling
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Kafrelsheikh University
Resistant Hypertension, Hemodynamic Instability
Effect of Electrical Stimulation and Exercise on Blood Flow in Patients With Resistant High Blood Pressure
The goal of this clinical trial is to learn if the combination between transcutaneous electrical nerve stimulation (TENS) and isometric exercise (IE) can improve blood pressure in men and women between 50 to 60 years old suffered…
- Conditions
- Resistant Hypertension, Hemodynamic Instability, Essential (Primary) Hypertension, Abdominal Obesity
- Trial name
- NCT07383220
- Testing
- Transcutaneous Electrical Nerve Stimulation, Isometric Exercise, Aerobic, Dynamic Resistance, stretch and Breathing Exercises and Lifestyle Modification Advices
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Mohamed Mohamed Ali Morgan
Hypertension (HTN)
Effects of a Health Literacy-tailored Self-management Intervention on People With Hypertension
This project aims to investigate the effects of a health literacy-tailored self-management intervention among people with hypertension and low health literacy.
- Trial name
- NCT07369479
- Testing
- health literacy-tailored self-management intervention
- Volunteers
- 170 people
- Sponsor
- Chinese University of Hong Kong