Clinical trials: Hypertension (HTN), open to volunteers
Hypertension (HTN), Hypertension
IMPACT-HTN Study of Patients With Hypertension
An estimated 120 million people have high blood pressure (hypertension) in the US, of which approximately 10% have resistant hypertension.
- Conditions
- Hypertension (HTN), Hypertension, Blood Pressure, High
- Trial name
- NCT07579260
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- Vivek Bhalla
Cardiometabolic Conditions, Hypertension (HTN)
To Test the Effectiveness and Implementation Approach of a 3-month PILI Pasifika Program Lifestyle Program With Components of Social Determinants of Health Activities in Real-world Settings (Clinical and Non-clinical Settings) Across 3 Years
In this study, the investigators are conducting a Type 3 hybrid effectiveness-implementation trial to evaluate the implementation of the Community Health Workers (CHW)-delivered PILI Pasifika Program (PPP) across 3 regions, the…
- Conditions
- Cardiometabolic Conditions, Hypertension (HTN), Dyslipidemia, Pre-diabetes
- Trial name
- NCT07387393
- Testing
- PILI (Partnership for Improving Lifestyle Intervention) Pasifika Program
- Where
- 2 sites in United States
- Volunteers
- 400 people
- Sponsor
- University of Hawaii
Food Insecurity, Diabetes in Adults
RUSH Food is Medicine Veggie Rx - GusNIP Produce Prescription
The goal of this clinical trial is to assess nutrition incentives and produce vouchers to measure the impacts of food insecurity-related chronic health conditions in adults with hypertension and/or diabetes.
- Conditions
- Food Insecurity, Diabetes in Adults, Hypertension (HTN)
- Trial name
- NCT07376044
- Testing
- Food is Medicine
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- Rush University Medical Center
Hypertension (HTN)
Actions to Decrease Disparities in Risk and Engage in Shared Support for Blood Pressure Control (ADDRESS-BP) in Blacks
To use practice facilitation (PF) + community health worker (CHW) facilitation as a practical and sustainable implementation strategy to support the implementation and evaluation of three multi-level evidence-based interventions…
- Trial name
- NCT05208450
- Testing
- Practice support And Community Engagement (PACE)
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- NYU Langone Health
Hypertension (HTN)
The Effect of Nurse-led Health Coaching on Blood Pressure Control and Disease Self-management Among Patients With Hypertension in Huayuan County, Western Hunan, China: a Randomized Controlled Trial
Background: Effective self-management of hypertension (HTN) is the key to adequate blood pressure control. The self-management education for patients with HTN has not been widely provided in Huayuan County, Western Hunan, China.
- Trial name
- NCT07606768
- Testing
- Nurse-led Health Coaching, Health guidance and follow-up management
- Where
- China
- Volunteers
- 39 people
- Sponsor
- The Third Xiangya Hospital of Central South University
Pregnancy, Pregnancy - Prenatal Testing
Effect of Isometric Handgrip Exercise on Blood Pressure in Pregnant Women
Hypertension during pregnancy is a major public health concern, increasing the risk of cardiovascular complications for both the mother and the fetus.
- Conditions
- Pregnancy, Pregnancy - Prenatal Testing, Hypertension (HTN)
- Trial name
- GRIP4HEALTH (NCT07607795)
- Testing
- Isometric Handgrip Exercise, Control Rest
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Poitiers
Hypertension (HTN)
QLS1410 in Participants With Uncontrolled Hypertension
The goal of this clinical trial is to measure the efficacy and safety of QLS1410 in participants with uncontrolled hypertension (uHTN) or treatment-resistant hypertension (rHTN).
- Trial name
- NCT07489612
- Testing
- Dose 1 of QLS1410, Dose 2 of QLS1410, Dose 3 of QLS1410
- Where
- China
- Volunteers
- 260 people
- Sponsor
- Qilu Pharmaceutical Co., Ltd.
Hypertension (HTN), Heart Failure With Preserved Ejection Fraction (HFpEF
Clinical Feasibility of Cardiac Neuromodulation Therapy for Heart Failure With Preserved Ejection Fraction
This is an open-label pilot study to evaluate the feasibility of Cardiac Neuromodulation Therapy (CNT) in patients with high blood pressure and heart failure who require dual-chamber pacemaker implantation or replacement.
- Conditions
- Hypertension (HTN), Heart Failure With Preserved Ejection Fraction (HFpEF, Hypertension, Systolic
- Trial name
- NCT07598760
- Testing
- Moderato Plus device with Cardiac Neuromodulation Therapy
- Where
- 2 sites in Georgia
- Volunteers
- 20 people
- Sponsor
- BackBeat Medical Inc
Atrial Fibrillation (AF), Hypertension (HTN)
Out-of-office Monitoring for Rhythms Of Normal Versus Atrial Fibrillation
The goal of this clinical trial is to learn if screening for atrial fibrillation (AFib), a common irregular heart rhythm, through daily home blood pressure monitoring will decrease the time to atrial fibrillation diagnosis in…
- Conditions
- Atrial Fibrillation (AF), Hypertension (HTN), High Blood Pressure
- Trial name
- OMRON-AF (NCT07582523)
- Testing
- Blood Pressure Monitor Without AFib Detection, Blood Pressure Monitor With AFib Detection
- Where
- United States
- Volunteers
- 1,910 people
- Sponsor
- University of California, San Francisco
Vascular Stiffness, Hypertension (HTN)
Low Energy Availability and Hypertension in Division I HBCU Athletes
Low energy availability (LEA) occurs when the body does not get enough calories to support both daily life and exercise. This can happen when athletes train hard but do not eat enough to match their energy needs.
- Conditions
- Vascular Stiffness, Hypertension (HTN), Nutritional Deficiency Related Cardiovascular Risk in Athletes
- Trial name
- CORE-DI (NCT07583940)
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- North Carolina Agriculture & Technical State University
Hypertension (HTN)
Automatically Transmitted Home Blood Pressure and Automated Patient Feedback in Hypertension Care: the AUTO 2 Trial
The purpose of this study is to evaluate the effectiveness of automatically-generated medical advice to patients about to their home blood pressure monitoring results sent through patient portal messages compared to no automated…
- Trial name
- AUTO 2 (NCT07397260)
- Testing
- Self report of home measured blood pressure via patient EHR portal, Automated feedback about home blood pressure results, Automated Transmission of Remotely Measured Blood Pressure
- Where
- United States
- Volunteers
- 1,304 people
- Sponsor
- Northwestern University
Type 2 Diabetes Mellitus (T2DM), Hypertension (HTN)
Cohort Study of Metabolic Disease and Hypertension
The goal of this observational study is to learn how type 2 diabetes and high blood pressure develop over time in adults in Mexico.
- Trial name
- NCT07577063
- Testing
- Observational Study
- Where
- Mexico
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- Coordinación de Investigación en Salud, Mexico
Blood Pressure Monitoring, Hypertension (HTN)
Community Health Worker Coaching to Reduce Cardiovascular Risk Among Women After a Hypertensive Disorder of Pregnancy
The goal of this clinical trial is to find out whether an enhanced program works better than remote blood pressure monitoring (RBPM) alone for women who had high blood pressure during pregnancy.
- Conditions
- Blood Pressure Monitoring, Hypertension (HTN), Pregnancy
- Trial name
- HERHEART (NCT07457970)
- Testing
- Enhanced Care Group, Remote Blood Pressure Monitoring alone
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- University of South Carolina
Hypertension (HTN), Pre Hypertension
The Effects of Brief Periods of Exercise on Blood Pressure
High blood pressure is a common medical condition that affects the body's arteries. It's also called hypertension. Untreated hypertension increases the risk of heart attack, stroke and other serious health problems.
- Trial name
- NCT07453550
- Testing
- wall-squat, wall-squat-tradition
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Hartford
Hypertension (HTN), Type 2 Diabetes
Integrating Care for Hypertension-Diabetes MULTImorbidity in Guatemala Through HEARTS Implementation
The purpose of this study is to find out whether a program called HEARTS can improve care for people who have both high blood pressure and diabetes.
- Trial name
- MULTI-HEARTS (NCT07536919)
- Testing
- HEARTS implementation strategies, Supply chain strengthening
- Volunteers
- 1,440 people
- Sponsor
- University of Michigan
Hypertension (HTN)
WEARABLE-BP: Wearable Everyday Automated Readings to Enable Assessment of Blood Pressure Control
The WEARABLE-BP study will evaluate the clinical value of obtaining continual measurements using the Aktiia G1 Optical Blood Pressure Monitoring (OBPM) device in hypertensive patients, compared to using a traditional upper arm…
- Trial name
- WEARABLE-BP (NCT07523269)
- Testing
- Aktiia G1 BP monitor for 12 months, Traditional BP monitor for 6 months / Aktiia G1 BP monitor for 6 months
- Where
- United States
- Volunteers
- 164 people
- Sponsor
- Aktiia SA
Hypertension (HTN), Age More 60yr
Empirical Study on Lifestyle Intervention for Elderly Hypertensive Patients in Community Based on TTM Theory
This study intervention is based on TTM theory and implements lifestyle interventions, including nutritious diet, regular exercise, social support, sleep optimization, avoidance of addictive substances, and stress management.
- Trial name
- NCT07492290
- Testing
- Lifestyle medicine
- Volunteers
- 106 people
- Sponsor
- Qu Shen
Hypertension (HTN), Hyperhomocysteinemia
Homocysteine and Early Diastolic Dysfunction in Newly Diagnosed Hypertension
This prospective single-center observational study aims to evaluate the relationship between elevated plasma homocysteine levels and early echocardiographic abnormalities in patients with newly diagnosed essential hypertension.
- Conditions
- Hypertension (HTN), Hyperhomocysteinemia, Diastolic Dysfunction
- Trial name
- HHT-EDD (NCT07480265)
- Testing
- Homocysteine Measurement and Echocardiography
- Where
- Turkey (Türkiye)
- Volunteers
- 500 people
- Sponsor
- Necmettin Erbakan University
Hypertension (HTN)
NR and Exercise for Blood Pressure
Hypertension continues to pose a significant global health challenge, with rates of optimal blood pressure control remaining low - particularly in China, where fewer than 5% of individuals with hypertension achieve…
- Trial name
- NCT07475208
- Testing
- Brisk walking, Nicotinamide Riboside 1000 mg
- Volunteers
- 112 people
- Sponsor
- ZHANG Jiaqi
Hypertension (HTN), Cardiometabolic Diseases
Genetic Architecture of Natriuretic Peptides and Blood Pressure Response
Natriuretic peptides (NPs) are hormones produced by the heart and play an important role in maintaining cardiovascular health and have favorable metabolic benefits.
- Trial name
- NCT07118592
- Testing
- Low Salt Diet, High Salt Diet, Saline Infusion
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham